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An Experimental Model: Modifications of the Chemical Silicone Medical Characteristics for an Improved Biocompatibility

Tian-Xi Li, Ming-Fei Lang, Di-Ya Su, Chen Zhang, Shi-Hui Wang, Xiao-Ying Dong, Cheng Han, Jie-Qing Wang, Jing Sun

Aesthetic Plastic Surgery · 2026

Vollständiger Abstract

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Abstract Objective Despite its good biocompatibility and processability, the severe surface hydrophobicity of polydimethylsiloxane (PDMS) limits its biomedical applications. This study aimed to enhance the surface properties of PDMS by depositing gelatin onto it via polydopamine (PDA) mediation and to evaluate the resulting cell–material interactions. Methods and Results The 1% gelatin-modified PDA-PDMS (G-PDA-PDMS) group showed the highest cell viability at 48 h. Surface hydrophilicity was significantly improved, with the contact angle reduced to 21.97° ± 2.06 ( p

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Autor:innen
Tian-Xi Li, Ming-Fei Lang, Di-Ya Su, Chen Zhang, Shi-Hui Wang, Xiao-Ying Dong, Cheng Han, Jie-Qing Wang, Jing Sun
Quelle
Aesthetic Plastic Surgery
Publikation
2026-01-01
Band / Ausgabe
Nicht angegeben
Seiten
Nicht angegeben
ISSN / ISBN
0364-216X, 1432-5241
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Tian-Xi Li, Ming-Fei Lang, Di-Ya Su, Chen Zhang, Shi-Hui Wang, Xiao-Ying Dong, Cheng Han, Jie-Qing Wang, Jing Sun (2026). An Experimental Model: Modifications of the Chemical Silicone Medical Characteristics for an Improved Biocompatibility. Aesthetic Plastic Surgery. https://doi.org/10.1007/s00266-026-05970-5
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