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Ensuring trustworthy AI assisted guideline development for clinical practice

Quan Zhang, Yuanyuan Fu

npj Digital Medicine · 2026

Vollständiger Abstract

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Abstract Li et al. introduce Quicker, an agentic large language model system that drafts clinical guideline recommendations through a GRADE-based workflow. Building on gaps in the authors’ own evaluation, we propose safeguards for trustworthy use: verifiable, design-aware evidence bundles with explicit scope; calibrated, uncertainty-aware deferral; targeted human validation and modular quality gates; and governance against contamination and over-reliance. Trustworthiness, however, is necessary but not sufficient for clinician trust.

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Publikationsdaten

Autor:innen
Quan Zhang, Yuanyuan Fu
Quelle
npj Digital Medicine
Publikation
2026-01-01
Band / Ausgabe
Nicht angegeben
Seiten
Nicht angegeben
ISSN / ISBN
2398-6352
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Zitierfähiger Nachweis

Quan Zhang, Yuanyuan Fu (2026). Ensuring trustworthy AI assisted guideline development for clinical practice. npj Digital Medicine. https://doi.org/10.1038/s41746-026-03098-z
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