Vollständiger Abstract
Worum geht es in dieser Arbeit?
Abstract Clinical Trial Centers (CTCs) manage complex multi-site trials under rising regulatory and operational demands. Traditional workflows are labor-intensive and error-prone. Existing AI handles narrow and siloed tasks. We introduce Agent System for TRial Automation (ASTRA), a proposed multi-agent CTC in which a central Coordinator Agent and site-level Agents orchestrate domain-specialized AI-agent teams under human supervision. In this framework, agents follow standard messaging using shared environments and a version-controlled knowledge base. This manuscript introduces ASTRA as a design framework and summarizes key implementation and regulatory challenges for this hybrid automation-plus-oversight model.
Bibliografischer Nachweis
Publikationsdaten
- Autor:innen
- Bjorn Redfors, Weishen Pan, Chen Lyu, Mario Gaudino, Fei Wang, Hua Judy Zhong
- Quelle
- npj Digital Medicine
- Publikation
- 2026-01-01
- Band / Ausgabe
- Nicht angegeben
- Seiten
- Nicht angegeben
- ISSN / ISBN
- 2398-6352
- Zitationen
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Zitierfähiger Nachweis
Bjorn Redfors, Weishen Pan, Chen Lyu, Mario Gaudino, Fei Wang, Hua Judy Zhong (2026). Towards a multi-agent Clinical Trial Center framework to support modern clinical trials. npj Digital Medicine. https://doi.org/10.1038/s41746-026-03158-4
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