Vollständiger Abstract
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Introduction: Adolescents and young adults living with HIV (AYLHIV) experience poor outcomes across the care continuum, and most reside in sub-Saharan Africa. The African Cohort Study (AFRICOS) provides an opportunity to examine HIV outcomes in this population across Kenya, Nigeria, Tanzania, and Uganda. Methods: We conducted a cross-sectional analysis of AYLHIV aged 15–29 years, enrolled in AFRICOS 2013-2023, and on antiretroviral therapy (ART) ≥ six months. Primary outcomes were HIV viremia and 30-day ART non-adherence. Factors included HIV acquisition route, ART duration, ART class, and site. We used multivariate robust Poisson regression to estimate relative risks (RRs) and 95% confidence intervals (CIs). Site directors were surveyed to assess youth-friendly services. Results: Among 656 participants, the median age was 20.0 years (IQR 17.5–23.3); 41.6% were male, 61.6% had perinatally-acquired HIV, and median duration since HIV diagnosis was nine years. At enrollment, 83.8% had viral suppression (
Bibliografischer Nachweis
Publikationsdaten
- Autor:innen
- Marie A. Brault, Aima A. Ahonkhai, Seth Frndak, Susannah Colt, Trevor A. Crowell, Ajay Parikh, Emma R. Duff, Valentine Sing’oei, John Owuoth, Jonah Maswai, Zahra Parker, Emmanuel Bahemana, Hannah Kibuuka, Sten H. Vermund, Neha Shah, Julie A. Ake
- Quelle
- JAIDS Journal of Acquired Immune Deficiency Syndromes
- Publikation
- 2026-01-01
- Band / Ausgabe
- Nicht angegeben
- Seiten
- Nicht angegeben
- ISSN / ISBN
- 1525-4135, 1944-7884
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Marie A. Brault, Aima A. Ahonkhai, Seth Frndak, Susannah Colt, Trevor A. Crowell, Ajay Parikh, Emma R. Duff, Valentine Sing’oei, John Owuoth, Jonah Maswai, Zahra Parker, Emmanuel Bahemana, Hannah Kibuuka, Sten H. Vermund, Neha Shah, Julie A. Ake (2026). Factors associated with viral suppression and antiretroviral therapy adherence among adolescents and young adults living with HIV in the African Cohort Study. JAIDS Journal of Acquired Immune Deficiency Syndromes. https://doi.org/10.1097/qai.0000000000003959