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One-Year Outcomes of M-TEER With the PASCAL System in Atrial and Ventricular FMR: Insights From the MiCLASP Postmarket Clinical Follow-Up Study

Amir A. Mahabadi, Tienush Rassaf, Tobias Kister, Thomas Schmitz, Tobias Geisler, Edith Lubos, Jörg Hausleiter, Ingo Eitel, Ralph Stephen von Bardeleben, Sergio Berti, Axel Linke, Christian Hengstenberg, Volker Rudolph, Bernhard Unsöld, Paolo Denti, Stephan Baldus, Georg Nickenig, Helge Möllman, Konstantinos Spargias, Nedy Brambilla, Christian Butter, Wolfgang Rottbauer, Markus Reinthaler, Martin Swaans, Fabien Praz, Adam Witkowski, Nicolas M. Van Mieghem, Mamta Buch, Frieder Wolf, Frank Edelmann, Leo Marcoff, Konstantinos Koulogiannis, Philipp Lurz

Circulation: Cardiovascular Interventions · 2026

Vollständiger Abstract

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BACKGROUND: Studies on mitral transcatheter edge-to-edge repair for atrial functional mitral regurgitation (AFMR) and ventricular functional mitral regurgitation (VFMR) are limited. METHODS: We report 1-year outcomes of mitral transcatheter edge-to-edge repair for AFMR and VFMR using the PASCAL transcatheter valve repair system in the MiCLASP multicenter European postmarket clinical follow-up study (REGISTRATION: URL: https://www.clinicaltrials.gov ; Unique identifier: NCT04430075). RESULTS: Analysis included 295 patients with functional mitral regurgitation (75.5±9.93 years old, 59.3% male) from the first 600 enrolled in the MiCLASP study, with AFMR in 17.6% (52) and VFMR in 82.4% (243). Patients with AFMR were older (79.7±6.67 versus 74.6±10.30 years), majority female (75.0% versus 33.3%), and had higher rates of hypertension (98.1% versus 82.3%) and atrial fibrillation (82.7% versus 60.1%) than patients with VFMR (all P

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Publikationsdaten

Autor:innen
Amir A. Mahabadi, Tienush Rassaf, Tobias Kister, Thomas Schmitz, Tobias Geisler, Edith Lubos, Jörg Hausleiter, Ingo Eitel, Ralph Stephen von Bardeleben, Sergio Berti, Axel Linke, Christian Hengstenberg, Volker Rudolph, Bernhard Unsöld, Paolo Denti, Stephan Baldus, Georg Nickenig, Helge Möllman, Konstantinos Spargias, Nedy Brambilla, Christian Butter, Wolfgang Rottbauer, Markus Reinthaler, Martin Swaans, Fabien Praz, Adam Witkowski, Nicolas M. Van Mieghem, Mamta Buch, Frieder Wolf, Frank Edelmann, Leo Marcoff, Konstantinos Koulogiannis, Philipp Lurz
Quelle
Circulation: Cardiovascular Interventions
Publikation
2026-01-01
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Seiten
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ISSN / ISBN
1941-7640, 1941-7632
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Amir A. Mahabadi, Tienush Rassaf, Tobias Kister, Thomas Schmitz, Tobias Geisler, Edith Lubos, Jörg Hausleiter, Ingo Eitel, Ralph Stephen von Bardeleben, Sergio Berti, Axel Linke, Christian Hengstenberg, Volker Rudolph, Bernhard Unsöld, Paolo Denti, Stephan Baldus, Georg Nickenig, Helge Möllman, Konstantinos Spargias, Nedy Brambilla, Christian Butter, Wolfgang Rottbauer, Markus Reinthaler, Martin Swaans, Fabien Praz, Adam Witkowski, Nicolas M. Van Mieghem, Mamta Buch, Frieder Wolf, Frank Edelmann, Leo Marcoff, Konstantinos Koulogiannis, Philipp Lurz (2026). One-Year Outcomes of M-TEER With the PASCAL System in Atrial and Ventricular FMR: Insights From the MiCLASP Postmarket Clinical Follow-Up Study. Circulation: Cardiovascular Interventions. https://doi.org/10.1161/circinterventions.126.016563
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