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Long-term survival outcomes following resection of lung metastases (LM) from a colorectal primary.

Sangeetha Ramanujam, Catherine Dunn, Phillip Antippa, Suzanne Kosmider, Yat Hang To, Margaret Lee, Vanessa Wong, Susan Caird, Jeremy David Shapiro, Joseph James McKendrick, Hui-Li Wong, Brigette Ma, Stephanie Hui-Su Lim, Javier Torres, Allan Solomon Zimet, Belinda Lee, Peter Gibbs

Journal of Clinical Oncology · 2022

Vollständiger Abstract

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50 Background: Liver metastatectomy in oligometastatic colorectal cancer (CRC) can result in long-term disease control 1 . The benefit of resecting LM is unclear, with good survival outcomes from medical therapy (MT) alone and a recent randomised controlled trial failed to demonstrate an overall survival (OS) benefit 2 . Methods: We examined TRACC (Treatment of Recurrent and Advanced Colorectal Cancer), a multisite registry for metastatic colorectal cancer (mCRC) patients (pts) from September 2002 – July 2021, focusing on the longer-term outcomes for pts with lung only metastatic disease (LOM). Key clinicopathological, treatment and outcome variables were analysed. Survival outcomes were determined by Kaplan-Meier method. Results: Of 3928 pts, 341 (8.7%) had LOM. The median OS was significantly improved for LOM vs. all mCRC pts (44.5 months vs. 24.8 months, p =

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Autor:innen
Sangeetha Ramanujam, Catherine Dunn, Phillip Antippa, Suzanne Kosmider, Yat Hang To, Margaret Lee, Vanessa Wong, Susan Caird, Jeremy David Shapiro, Joseph James McKendrick, Hui-Li Wong, Brigette Ma, Stephanie Hui-Su Lim, Javier Torres, Allan Solomon Zimet, Belinda Lee, Peter Gibbs
Quelle
Journal of Clinical Oncology
Publikation
2022-01-01
Band / Ausgabe
Nicht angegeben
Seiten
Nicht angegeben
ISSN / ISBN
0732-183X, 1527-7755
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Sangeetha Ramanujam, Catherine Dunn, Phillip Antippa, Suzanne Kosmider, Yat Hang To, Margaret Lee, Vanessa Wong, Susan Caird, Jeremy David Shapiro, Joseph James McKendrick, Hui-Li Wong, Brigette Ma, Stephanie Hui-Su Lim, Javier Torres, Allan Solomon Zimet, Belinda Lee, Peter Gibbs (2022). Long-term survival outcomes following resection of lung metastases (LM) from a colorectal primary. Journal of Clinical Oncology. https://doi.org/10.1245/s10434-026-20313-z
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