10.3389/fpsyg.2012.00132

Vollständiger Abstract

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<h4>Background</h4>Patients undergoing colorectal cancer surgery are at risk of postoperative nutritional deterioration due to perioperative metabolic stress, inflammation, and transient gastrointestinal dysfunction. Evidence-based, nursing-led nutritional pathways may improve perioperative nutritional surveillance and timely nutrition support.<h4>Methods</h4>This retrospective study included 214 adults who underwent elective curative-intent colorectal cancer resection between January 2023 and December 2024. Patients receiving routine perioperative nursing care in 2023 were assigned to the control group (<i>n</i> = 106), whereas those receiving the nutrition-focused evidence-based nursing protocol in 2024 were assigned to the observation group (<i>n</i> = 108). The primary outcomes were change in Nutritional Risk Screening 2002 (NRS-2002) score and postoperative nutritional risk, defined as NRS-2002 ≥ 3 at postoperative day 7 or immediately before discharge.<h4>Results</h4>Baseline characteristics were comparable between groups. The observation group had lower postoperative NRS-2002 scores and smaller ΔNRS-2002 than the control group (both <i>P</i> < 0.001). Postoperative nutritional risk was also lower in the observation group (44.4% vs. 67.0%, <i>P</i> = 0.001). After multivariable adjustment, the observation group remained associated with lower odds of postoperative nutritional risk (adjusted odds ratio = 0.17, 95% confidence interval: 0.08-0.36; <i>P</i> < 0.001). Secondary findings showed less weight loss, smaller declines in albumin and prealbumin, lower discharge C-reactive protein, earlier feeding recovery, shorter postoperative hospital stay, fewer overall complications, and fewer nutrition-support-related safety events.<h4>Conclusions</h4>A nutrition-focused evidence-based nursing protocol was associated with more favorable postoperative nutritional risk status assessed by NRS-2002, as well as selected short-term recovery- and safety-related outcomes after colorectal cancer surgery. These findings should be interpreted as associative and require confirmation in prospective studies.

Abstract: PubMed · Datensatz