Vollständiger Abstract
Worum geht es in dieser Arbeit?
The aim of the study was to determine the feasibility of de-escalation of the volume of lymphodissection by performing selective target biopsy of the sentinel lymph node in patients with initial stage cN1 disease who progressed to cN0 after NACT and demonstrate that this approach does not result in worsening oncological outcomes or local recurrences. For this purpose, 345 patients with primary operable breast cancer were studied. In the first stage, the patients received NACT followed by radical surgery in the period 2023–2024. The results revealed that 98.2% of patients had no signs of tumor growth in thе regional areas and achieved a complete clinical response after NACT. This provides grounds for abandoning extended axillary dissections.
Bibliografischer Nachweis
Publikationsdaten
- Autor:innen
- D.A. Karseladze, K.S. Titov, I.N. Lebedinsky, I.N. Kutz, D.D. Dolidze, S.S. Lebedev, A.A. Tatarova, E.Yu. Neretin
- Quelle
- Effective Pharmacotherapy
- Publikation
- 2026-01-01
- Band / Ausgabe
- Nicht angegeben
- Seiten
- Nicht angegeben
- ISSN / ISBN
- 2307-3586
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Zitierfähiger Nachweis
D.A. Karseladze, K.S. Titov, I.N. Lebedinsky, I.N. Kutz, D.D. Dolidze, S.S. Lebedev, A.A. Tatarova, E.Yu. Neretin (2026). Justification for the Redundancy of Wide Axillary Llymphodissection in Patients with Early Breast Cancer who Developed Ttransformation from Iinitial cN1 to Complete Clinical Response after Neoadjuvant Chemotherapy. Effective Pharmacotherapy. https://doi.org/10.33978/2307-3586-2026-22-22-20-23