The correlation between depression and haemodialysis adequacy in chronic kidney disease patients in South Africa

Vollständiger Abstract

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Background: Chronic kidney disease (CKD) is a global health concern projected to be the fifth most prevalent chronic disease by 2040, associated with high mortality and significant psychosocial burdens. Aim: This study aimed to explore and describe the correlation between depression and haemodialysis adequacy in CKD patients. Setting: Research was conducted across five units in the Free State and Northern Cape provinces, South Africa. Methods: This quantitative, cross-sectional, prospective analytic study included 78 patients selected via convenience sampling, and trustworthiness and ethical principles were adhered to throughout the study. A biostatistician analysed the raw data using the statistical analysis system (SAS). Data collected over 3 months involved objective measurements of online dialysis adequacy (Kt/V) and pathology (creatinine, urea), alongside subjective depression assessments using the Beck Depression Inventory (BDI). Results: The median BDI score was 17 (Interquartile range [IQR]: 13–22), r