Vollständiger Abstract
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Strophanthus hispidus DC (Apocynaceae) is a valued African plant that has been used as a remedy of various disease conditions. This study identified compounds present using GC-MS as well as the potential antidiabetic effects of the n-butanol, ethyl acetate, and aqueous fractions. Gas Chromatography Mass Spectrometry (GC-MS) was carried out using the Agilent 7890 A GC with a J&W HP-5MS column (30 m x 0.320 mm i.d. x 0.25 μm). The effects of the fractions (100 mg/kg each) on blood glucose levels, body weight, biochemical parameters, lipid profile, serum insulin, hepatic glycogen, and haemoglobin levels were evaluated in alloxan-induced hyperglycaemic rats. The GC-MS analysis revealed the presence of Decanoic acid methyl ester; methyl 15-acetoxy hexadecanoate; Hydrazine propyl; and Cyclobut-1-enyl methanol. A significant (p
Bibliografischer Nachweis
Publikationsdaten
- Autor:innen
- Muyiwa SAMUEL FAGEYINBO, Temitayo ESTHER ADEYEOLUWA, Abidemi JAMES AKINDELE, Esther OLUWATOYIN AGBAJE
- Quelle
- African Journal of Pharmacy and Alternative Medicine
- Publikation
- 2026-01-01
- Band / Ausgabe
- Nicht angegeben
- Seiten
- Nicht angegeben
- ISSN / ISBN
- 3005-6306, 3005-6306
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Zitierfähiger Nachweis
Muyiwa SAMUEL FAGEYINBO, Temitayo ESTHER ADEYEOLUWA, Abidemi JAMES AKINDELE, Esther OLUWATOYIN AGBAJE (2026). Gas Chromatography-Mass Spectrometry Analysis and Antidiabetic Effect of Fractionated Extract of Strophanthus hispidus. African Journal of Pharmacy and Alternative Medicine. https://doi.org/10.58460/ajpam.v5i02.196
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