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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
26.08.2026journal-article

NCVS Insights

Is It Self-Awareness or Is It Sensory Feedback? Difficulties in Self-Perception of One's Own Voice in People with Parkinson's Disease

Francisco Contreras-Ruston

Parkinson’s disease (PD) is widely known for its impact on movement: tremor, rigidity, and slowed gait. Less visible, but equally disabling, are the changes it imposes on the voice (Duffy, 2020). Most people with PD (PwPD) develop hypokinetic dysarthria, the first symptom of which is usually reduced vocal intensity (a hallmark of hypophonia), along with a diminished pitch range and reduced articulatory precision (Duffy, 2020). These changes compromise communication quality and, consequently, social participation an …

26.08.2026journal-article

Journal of General Education and Humanities

Existence of The Menyilaq Tradition Among the Sasak People in the Face of The Advance of Modern Information Technology

Suhadah Suhadah, Fathurrijal Fathurrijal, Nur Ilham, Naoval Rahman, Baiq Ida Astini, Kadri Kadri

This study aims to examine the existence of the menyilaq tradition among the Sasak people, identify the dynamics of change resulting from the development of modern information technology, and uncover the adaptation and preservation strategies used to maintain cultural and social values, as well as local wisdom, in the digital age. The study employs a qualitative descriptive approach, with research sites in Mataram City, West Lombok Regency, and North Lombok Regency that represent urban, suburban, and indigenous com …

26.08.2026journal-article

Frontiers in Aging

Repurposing MK0873 as a non-covalent hTERT-Targeting compound: a proof of concept study

Maham Ansari, Abdul Wali, Mohhamed Rasul, Kristina Gemzell Danielsson, Twana Alkasalias, Muhammad Mushtaq

Telomerase is a key regulator of both cellular immortality and aging, making it an attractive target for cancer therapy and age associated pathologies. Its clinical exploitation has been limited by structural complexity and challenges in achieving specificity. Recent structural insights into human telomerase reverse transcriptase (hTERT) have enabled the identification of selective inhibitors. Here, we repurposed MK0873, a PDE4 inhibitor previously evaluated in Phase II clinical trials for rheumatoid arthritis and …

26.08.2026journal-article

WORLD JOURNAL OF INNOVATION AND MODERN TECHNOLOGY

Environmental Education Programs for Discouraging Destruction of Aquatic Lives Among Kalabari People in Rivers State

Ijeoma Roseline John

This study examined environmental education programmes for discouraging destruction of aquatic lives among kalabari people in Rivers State, Nigeria. Three research objectives, and three null hypotheses were used for the study. The study adopted a descriptive survey research design. The population of the study consists of 522 community inhabitants, comprising 326 male and 196 female fisher folks that are members of registered fishing folk’s association in the study area. The entire population was used for the study …

26.08.2026journal-article

Health Science Reports

Burden of Tension‐Type Headache Among Older Adults in the Middle East and North Africa Region, 1990–2023

Saeid Safiri, Ali‐Asghar Kolahi, Maryam Beigrezaee, Mostafa Araj‐Khodaei, Reza Aletaha, Mark J. M. Sullman, Koroush Gharagozli

ABSTRACT Background and Aims Tension‐type headache (TTH) is an under‐recognized but substantial contributor to disability and diminished quality of life among older adults. This study evaluated the burden of TTH among adults aged 60 years and older in the Middle East and North Africa (MENA) region and changes in burden between 1990 and 2023. Methods Data from the Global Burden of Disease (GBD) Study 2023 were used to report the prevalence, incidence, and years lived with disability (YLDs) due to TTH among adults ag …

26.08.2026journal-article

Addiction

Exploring the influence of user‐generated content on alcohol‐related attitudes and behaviours among young people: A systematic review

Alessandro Crocetti, Nichole Lister, Jennifer Browne, Florentine Martino, Kathryn Backholer, Benjamin Riordan, Peter Miller, Matthew Dunn

Abstract Background and aims Alcohol‐related content on social media, particularly user‐generated content (UGC), is an increasingly normal feature of young people's digital lives and has been linked to increased alcohol use; however, a critical gap remains in understanding how different subgroups of young people are exposed to and engage with such content, and how this may be associated with their alcohol‐related attitudes and behaviours. This systematic review aimed to synthesise evidence on the association betwee …

26.08.2026journal-article

Diseases

A Pilot Study on the Evaluation of an Inpatient Glycaemic Management Protocol for Enteral Feeding in People with Diabetes

Shayna Xueli Lin, Di Zhang, Khee Ling Choo, Qinghua Tan, Puja Sharda, Nur Kalimallah Khairul Anwar, Xin Yi Hannah Luah, Zongwen Wee, Priscilla Chiam Pei Sze, Angela Koh Fang Yung, Sueziani Bte Zainudin, Ling-Jun Chen

Aims: International diabetes guidelines recommend inpatient glycaemic management protocols for bolus enteral feeding in people with diabetes to improve clinical outcomes. This study aims to evaluate before and after hospital-wide implementation of an inpatient bolus enteral feeding protocol: (1) the incidence of hyperglycaemia (>13.9 mmol/L) and hypoglycaemia (<4.0 mmol/L), (2) medication prescribing practices and capillary blood glucose monitoring and (3) health care professionals’ knowledge and confidence levels. …

26.08.2026journal-article

AIDS

Long-term effectiveness of bictegravir/emtricitabine/tenofovir alafenamide in people with HIV and resistance-associated mutations

Cinthia S. Lamaizón, Diego Cecchini, Martin Brizuela, Gastón Copertari, Brenda Bacelar, Macarena Roel, Edgardo Bottaro, Lidia I. Cassetti

Resistance-associated mutations (RAMs) limit treatment options for HIV. We evaluated virologic outcomes in people with HIV harboring RAMs who switched to bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) in a real-world cohort during 4 years of follow-up. Virologic suppression was sustained across RAM subgroups, including M184V/I with additional nucleoside reverse transcriptase inhibitor (NRTI)-RAMs. Stratification by genotypic susceptibility score (GSS) suggests robust effectiveness. B/F/TAF demonstrates d …

26.08.2026journal-article

BMC Infectious Diseases

Seroprevalence update of Hepatitis B Virus, Hepatitis C Virus, and human immunodeficiency virus among people who inject drugs in Kuwait: a cross-sectional study at a national addiction treatment center

Haya Altawalah, Farah Altannak, Karima Abounouh, Sayeh Ezzikouri

Abstract Background People who inject drugs (PWID) represent a key population disproportionately affected by blood-borne viruses. Updated epidemiological data are crucial for informing public health interventions. This study provides a 2024 update on the seroprevalence and correlates of Hepatitis B (HBV), Hepatitis C (HCV), and Human Immunodeficiency Virus (HIV) among PWID at Kuwait’s national addiction treatment center, building on a previous 2017 baseline. Methods A cross-sectional study was conducted from Januar …

26.08.2026journal-article

Frontiers in Public Health

The PATHS survey: a participatory-informed, multilingual instrument for assessing tobacco and nicotine-related knowledge, attitudes, and behaviours among people with a migration background in Switzerland

Kris Schürch, Tayisiya Krasnova, Nathalia Gonzalez-Jaramillo, Emilia B. Nordmeyer, Luciano Ruggia, Annika Frahsa

Introduction Research on tobacco and nicotine use among people with migration backgrounds is characterised by methodological limitations, including a predominant focus on behavioural outcomes, limited integration of knowledge and attitudes, and a lack of participatory approaches. Standard population surveys further restrict linguistic accessibility and often fail to capture the complexity of migration-related experiences, thereby limiting the interpretability of observed health inequalities. We thus aimed to develo …

26.08.2026journal-article

Bulletin of Faculty of Physical Therapy

Current state of entry-level geriatric physiotherapy curriculum in Kenya

Karen M. Blood, Justin T. Mierzwicki, Barbara Billek-Sawhney

Abstract Background Kenya is experiencing a shift in the demographic profile towards a higher percentage of older adults. Physiotherapists must possess a strong knowledge base to meet the unique needs of older adults to ensure quality outcomes. The purposes of this study were to evaluate the level of preparation of Kenyan physiotherapists related to the examination and treatment of older adults and identify the format with which geriatric physiotherapy education is delivered in entry-level physiotherapy programs. M …

26.08.2026journal-article

Canadian Journal of General Internal Medicine

The appropriate use of chemical and physical restraints for older adults

Shehraz Riar, Justin Lee

Abstract Restraint use remains common (and often overused) in older adults. In the Canadian healthcare system, 1 in 4 medical inpatients are physically or chemically restrained. Given the limited benefit and serious harms associated with restraint use, the decision to restrain a patient or not demands strong ethical and clinical justification. This review operationalizes the least restraint principle, synthesizes restraint practice recommendations, and provides a framework to support clinicians in determining the a …

26.08.2026journal-article

Nursing Reports

Effectiveness of M-Health Interventions to Improve Medication Adherence in People with Schizophrenia Spectrum Disorder: A Systematic Review

Worku Animaw Temesgen, Yuen Yee Lai, Ho Nam Suen, Wai Yan Chan, Pui Tik Yau, Wai Tong Chien, Yuen Yu Chong

Background: Mobile health interventions offer a potential solution to adherence challenges, yet evidence regarding their collective efficacy in schizophrenia spectrum disorders has not been formally synthesized. This systematic review evaluates the impact of mobile health (mHealth) interventions on medication adherence as a primary outcome and on daily functioning and psychotic symptoms as secondary outcomes in individuals with schizophrenia spectrum disorders. Methods: Using the Population, Intervention, Compariso …

26.08.2026journal-article

Frontiers in Robotics and AI

An online survey of encouragement strategies for older adults’ daily worries: a conversational robot versus a human partner

Lingxuan Xiang, Marin Nishimura, Hideaki Kikuchi

Conversational robots are increasingly proposed to provide everyday emotional support for older adults. However, it remains unclear which encouragement strategies are perceived as effective and whether interpersonal strategy preferences transfer to Human–Robot Interaction (HRI). This study compared the perceived effectiveness of five encouragement strategies when delivered by a conversational robot versus a human partner, examined moderation by worry type, and explored associations with recipients’ emotional states …

26.08.2026journal-article

Journal of Organizational Effectiveness: People and Performance

Beyond compliance: emerging ethical and strategic challenges in managing neurodiverse talent in the tourism and hospitality industry

Santus Kumar Deb, Hiran Roy, Md Istiaq Mohhamad Shuvo, William Phanuel Kofi Darbi

Purpose This study aims to evaluate the ethical dilemmas and challenges in managing neurodiverse talent in tourism and hospitality, and to understand how inclusion practices can move beyond compliance. Design/methodology/approach This study adopts a qualitative research design in which a semi-structured questionnaire was created for Key Informant Interview and In-Depth Interview with 19 respondents, including top executives from luxury hotels, family members of neurodiverse individuals, travel agencies, tour operat …

26.08.2026journal-article

Russian Bulletin of Obstetrician-Gynecologist

Evaluation of the effectiveness of local hormone therapy in older patients with pelvic descension

N.V. Yudina, A.E. Brylyaeva, S.N. Buyanova

Objective. To evaluate the results of pelvic descension correction in patients of the older age group on the background of combined treatment, including surgical intervention in combination with the use of local hormone therapy at the stages of preoperative preparation and postoperative rehabilitation. Materials and methods. The prospective study was conducted from 2024 to 2025 on the basis of the Moscow Regional Research Institute of Obstetrics and Gynecology named after Academician V.I. Krasnopolsky. The study in …

26.08.2026journal-article

Proceedings of the National Academy of Sciences

Aging limits neuronal regeneration from glia in the mouse retina

Jugasmita Deka, Ying Han, Sucheta Bhattacharya, Samantha Sutton, Galina Bachay, William J. Brunken, Levi Todd

Reprogramming resident glia into neurons holds great therapeutic promise for neurodegenerative diseases across the central nervous system, yet these strategies have been developed largely in young animals. Because aging is the primary risk factor for neurodegeneration, whether glia-to-neuron reprogramming remains effective in aged tissue is a critical unanswered question. Here, using the retina as an accessible part of the central nervous system, we show that aging is a major barrier to glia-to-neuron reprogramming …

26.08.2026journal-article

Pharmacoepidemiology and Drug Safety

The Process of Deprescribing in Older Adults With Potentially Inappropriate Medication or Polypharmacy: A Scoping Review

Mengnan Zhao, Zhaoyan Chen, Ying Zhang, Fangyuan Tian

ABSTRACT Objectives Deprescribing is increasingly recognized as an effective strategy for reducing potentially inappropriate medication (PIM) use and polypharmacy in older adults. However, existing deprescribing frameworks often lack detailed operational guidance, which may hinder their routine implementation in clinical practice. To systematically map and characterize the reported deprescribing processes in older adults with PIM use or polypharmacy and identify gaps in their operationalization. Methods PubMed, Emb …

26.08.2026journal-article

Cosmetics

A Well-Tolerated Supercritical CO2 Extract Derived from Helichrysum italicum Distillation Co-Products with Retinoid-Associated Anti-Aging Activity

Géraldine Lemaire, Malvina Olivero, Virginie Rouquet, Stéphanie Rivoire, Amélie Thepot, Morgan Dos Santos, Pascal Portes, Valérie Cenizo

Skin aging is characterized by various changes, including epidermal thinning, barrier dysfunction, dermis alteration, and dermal–epidermal junction flattening. These changes lead to wrinkles and loss of skin radiance. This study investigates the potential of a supercritical CO2 extract derived from Helichrysum italicum distillation co-products (CO2SC extract) to serve as a botanical anti-aging product, targeting epidermal renewal, barrier reinforcement, dermal–epidermal junction organization, and engagement of reti …

26.08.2026journal-article

Frontiers in Aging

Effect of sarcopenia and paraspinal muscle morphology on conservative treatment outcomes in lumbar spinal stenosis: a prospective cohort study

Zhangmeng Xu, Tao Xu, Jing Guo, Jinshun Zou, Jiajia Luo, Fan Chen, Xin Zhang, Ji Wu

Introduction The impact of sarcopenia on postoperative outcomes in lumbar spinal stenosis (LSS) is well documented, but its role in conservative treatment remains unclear. In this prospective cohort study, we examined the association between sarcopenia and outcomes after conservative treatment in elderly LSS patients and explored whether paraspinal cross-sectional area (CSA) and fat percentage mediate this relationship. Methods Elderly LSS patients undergoing conservative treatment at Sichuan Provincial Orthopedic …

26.08.2026journal-article

Health Science Reports

Factors Associated With Viral Suppression Among People Living With HIV (PLWH) in Kermanshah, Iran: A Retrospective Cohort Study

Etrat Javadirad, Mosayeb Rostamian, Seyedeh Shadi Vaziri, Leila Solouki, Bahare Andayeshgar, Sepideh Khodamoradi, Roya Chegene Lorestani, Keyghobad Ghadiri

ABSTRACT Background and Aims Despite the expanded availability of antiretroviral therapy (ART), HIV remains a major global health challenge. Viral load (VL) is the main indicator used to assess treatment response, and viral suppression is the ultimate goal of therapy. However, virological response is influenced by various patient‐ and treatment‐related factors. This study aimed to identify factors associated with viral suppression among PLWH in Kermanshah, Iran. Methods We included 2909 PLWH attending the Kermansha …

26.08.2026journal-article

Archives of Public Health

BMI and mortality among older adults in Belgium: the roles of age, sex, and frailty

Arne Noppe, Johan Van der Heyden, Hilde Baeyens, Ingrid Pelgrims, Sabine Drieskens, Anja Declercq, Brecht Devleesschauwer

Abstract Background Ageing populations and increasing prevalence of overweight are two of the main healthcare challenges worldwide. In 2023–2024, 49.7% of the Belgian population had overweight (BMI $$\ge$$ 25) and 3.1% of the population aged 65 years and above had underweight (BMI < 18.5). The health risks associated with high or low BMI and old age separately are well known. In addition, frailty is a key risk factor among older adults which is often associated with both mortality and BMI. Despite recent advances, …

26.08.2026journal-article

Interactive Journal of Medical Research

Digital Health Interventions Incorporating Behavior Change Techniques and Gamification for Bladder Health in Adults Aged 50 Years and Older: Rapid Review

Oscar Aguila-Gimeno, Norina Gasteiger, Emma Stanmore, Marius Brazaitis, Rima Solianik, Erika Karkauskiene, Laura Jarutienė, Júlia Romeu-Busquets, Javier Jerez-Roig

Abstract Background Urinary incontinence (UI) is the most prevalent pelvic floor dysfunction, with incidence increasing with age. Numerous studies have demonstrated the effectiveness of pelvic floor exercises in improving UI. However, access to pelvic floor treatment remains limited due to lengthy waiting lists and poor adherence to prescribed exercises. Digital solutions incorporating behavior change techniques (BCTs), including gamification elements, may support self-management of bladder health for individuals a …

26.08.2026journal-article

Frontiers in Neurology

Mortality patterns related to stroke and dementia among older adults in the U. S.: a CDC WONDER analysis from 1999 to 2024

Maryam Saghir, Eshal Saghir, Maliha Khalid, Muhammad Umar, Sahil Jairamani, Areej Dar, Hasiba Karimi, Muhammad Khalid Afridi, Syed Ijlal Ahmed, Jamal S. Rana, Elangovan Krishnan, Ishtiaq Ahmad, Suleman Sofian Suliman

Introduction Blood flow impairment due to stroke substantially causes neuronal loss, ultimately leading to cognitive decline. Dementia is a progressive neurocognitive disorder that represents a major public health challenge worldwide. Methods We analyzed stroke and dementia related mortality trends among older adults using the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research (CDC WONDER) database from 1999 to 2024. Age-Adjusted Mortality Rates (AAMRs) per 100,000 were c …