Future Pharmacology
Pharmacogenomic vs. Non-Pharmacogenomic Treatment in First-Episode Depression: A Randomized Clinical Trial
Background: Due to drug efficacy, adverse reactions, and individual differences, clinicians face significant challenges in drug selection for the treatment of depression. However, the study on predicting antidepressant treatment response based on pharmacogenomics has not yet been determined. Methods: A total of 178 participants were recruited and randomly assigned to either pharmacogenomics-guided antidepressant treatment or regular antidepressant treatment. All participants completed pharmacogenomic sampling at ba …