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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
30.08.2026journal-article

Journal of Clinical Apheresis

Predicting Non‐Target Neutrophil Collection During HPC (A): Implications for Research Protocols in Apheresis

Yandy Marx Castillo‐Aleman, Carlos Agustin Villegas‐Valverde, Yendry Ventura‐Carmenate, Shinnette Lumame, Jay Mary Rose‐Roque, Marlene Cato, Hamda Ali, Ruaa Mousa Ali, Rachely Hernandez‐Corrales, Anil Sarode, Yaima Zuñiga‐Rosales, Vianed Marsan‐Suarez, Antonio Alfonso Bencomo‐Hernandez

ABSTRACT Neutrophils are unintentionally co‐collected during HPC(A) procedures using mononuclear cell collection protocols. Although non‐target granulocyte co‐collection is generally clinically acceptable, excessive neutrophil content may compromise certain translational research applications. This study aimed to develop a predictive model for neutrophil yield during routine HPC(A). A retrospective single‐center analysis of 377 HPC(A) procedures performed between January 2023 and April 2026 was conducted. Donor dem …

30.08.2026journal-article

International Journal of Methods in Psychiatric Research

Comparing Administrative Data and Resident Assessment Instrument Data for Mental Health Surveillance in Home Care and Long‐Term Care Populations

Ruth Ann Marrie, James M. Bolton, Xueyi Chen, Erind Dvorani, Okechukwu Ekuma, Zahra Goodarzi, Andrea Gruneir, Jin Luo, Nathan Herrmann, Matthias Hoben, David B. Hogan, Andrea Iaboni, Dallas Seitz, Randy Walld, Walter P. Wodchis, Colleen J. Maxwell, EMHLTH‐CC Research Team

ABSTRACT Objectives To compare mental illness prevalence, and agreement between mental illness measures, in home care (HC) and long‐term care (LTC) using administrative definitions and Resident Assessment Instrument (RAI)‐diagnoses. Methods Applying a common protocol to linked administrative‐RAI datasets in Alberta, Manitoba, and Ontario, Canada, we selected adults receiving HC or LTC between 2012 and 2023. Cross‐sectionally, we compared administrative definitions with RAI‐diagnoses (depression, anxiety, bipolar di …

30.08.2026journal-article

Clinical and Experimental Pharmacology and Physiology

ANGII Initiated HSF2 Trans‐Activating HIF ‐1α Through Induction of ER Stress to Promote Cardiac Hypertrophy

Renchuang Cao, Qingying Meng, Gengyuan Li, Shumei Yuan, Chunmei Li, Xin Zhao, Dongmei Zhang

ABSTRACT Heat shock factor 2 (HSF2) and hypoxia‐inducible factor 1α are activated by angiotensin II (ANGII) in cardiomyocytes. The endoplasmic reticulum (ER) stress plays a critical role in cardiac hypertrophy. Moreover, HIF‐1α is known to be regulated by HSF2 in tumour cells. In this study, we hypothesised and clarified whether HSF2 trans‐activated HIF‐1α through initiation of ER stress in hypertrophic cardiomyocytes. Myocardial hypertrophy was induced by the treatment of ANGII. Expression of the gene or protein w …

30.08.2026journal-article

Physical Rehabilitation and Recreational Health Technologies

Adjunctive Soft-Skills Training Combined with Group-Based Psychosocial Support for Future Web Developers Screening Positive for Post-Traumatic Stress Symptoms During Wartime: A Three-Arm Quasi-Experimental Study

Nina Pidbutska, Anastasiia Knysh, Yuliia Chebakova, Yuliia Demidova

Purpose. Ukrainian web-development students face prolonged wartime stressors, yet psychosocial support tailored to this group remains scarce. We examined whether adding brief soft-skills training to group-based psychosocial support produced greater reductions in self-reported post-traumatic stress symptoms than support alone in students screening positive for probable PTSD. Materials & Methods. In a three-arm quasi-experimental study with random allocation (March–September 2024), 181 students scoring ≥33 on the PCL …

30.08.2026journal-article

Precision Radiation Oncology

Precise delineation of radiation targets for thoracic tumors in the immunotherapy era: from immune mechanisms to clinical practice

Xiaoying Chen, Minxiao Yi, Yu Deng, Qian Shen

Abstract As a core modality for local control of thoracic tumors, including lung and esophageal cancers, radiotherapy (RT) shows synergistic effects with immunotherapy, fundamentally reshaping the landscape of cancer treatment. Given the rapid advancements in immunotherapy, this review explores the critical role of precise delineation of radiotherapy targets in achieving synergistic effects between RT and immunotherapy. It elucidates the dual‐edged nature of RT, which can both activate antitumor immune responses an …

30.08.2026journal-article

Clinical Medicine (Russian Journal)

A non-invasive method for verification of acute mesenteric blood flow disorder

Magomed D. Dibirov, Rasul U. Gadzhimuradov, Igor P. Parfenov, Darya I. Sidorova, Vladimir S. Fomin

Acute mesenteric perfusion disorder (AMP) is a critical emergency condition characterized by a sudden reduction in blood flow through the mesenteric vessels to the intestine, leading to inadequate perfusion of the small intestine. Mortality from this pathology ranges from 50% to 97% and is primarily due to its rapid progression and subsequent development of intestinal necrosis. Diagnosis of AMP and intestinal ischemia remains a challenge for clinicians due to the lack of pathogmonic symptoms of the disease. In the …

30.08.2026journal-article

Health Science Reports

Mediterranean Diet and Micronutrient Adequacy in Relation to Relapsing‐Remitting Multiple Sclerosis Risk: A Case‐Control Study

Maryam Ahmadi‐Khorram, Alireza Hatami, Mostafa Shahraki Jazinaki, Yasaman Aali, Maedeh Nojoumi, Fatemeh Keykhaei, Ali Jafarzadeh Esfehani, Mohsen Nematy

ABSTRACT Background Multiple sclerosis (MS) is a chronic autoimmune and neurodegenerative disease influenced by environmental factors, including diet. The Mediterranean Diet (MeDi), rich in anti‐inflammatory and antioxidant compounds, and micronutrient adequacy may reduce MS risk and progression. Aim This study aims to examine the associations between the Mediterranean Diet Score (MDS), Mean Adequacy Ratio (MAR), and MS risk in a case‐control setting. Methods This case‐control study included 197 newly diagnosed rel …

30.08.2026journal-article

Journal of Artificial Intelligence and Information

From Diagnosis to Treatment: Advances in Clinical Research on Severe Pneumonia

Sheng Wang, Xiaoli Wu, Xiaoshuai Wu

Severe pneumonia is a life-threatening infectious disease associated with high mortality and is frequently complicated by acute respiratory distress syndrome, septic shock, and multiple organ dysfunction. The current diagnostic and therapeutic paradigm is shifting from empirical broad-spectrum treatment toward individualized management based on precise pathogen identification and assessment of the host response. The pathogenesis of severe pneumonia involves a broad range of bacterial, viral, and fungal pathogens, t …

30.08.2026journal-article

Health and Biosciences

<b>Investigação de surto de tuberculose em clínica de hemodiálise: uma ação intersetorial de saúde pública</b>

Maíce Vieira Marinho Henriques, Nayane Silva Almeida, Maria Luiza Vitoraci de Souza, Leticia Barletta, Murilo Soares Costa

Tuberculosis is an infectious disease whose transmission occurs through the air and the time of exposure to the pathogen. It presents itself as a major challenge to global public health and can be potentiated in hemodialysis units where patients with weakened immunity due to immunosuppression are found. Intersectorality, in turn, is the integration of services with the purpose of putting public policies into practice. The objective of the study was to describe the intersectoral investigation conducted in response t …

30.08.2026journal-article

Public Health Journal

Efektivitas Pemberian Jeruk Nipis Kecap Terhadap Balita ISPA di Wilayah Kerja UPTD Puskesmas Koncara Tahun 2026

Irena Endang Widuri, Nova Rati Lova, Elma Theana

Acute Respiratory Infection (ARI) is one of the common health problems among toddlers. Symptoms such as cough and respiratory discomfort may affect children's comfort and health status. One non-pharmacological supportive approach is the administration of lime juice combined with sweet soy sauce. This study aimed to determine the effectiveness of lime and soy sauce administration in reducing ARI symptoms among toddlers in the working area of Koncara Public Health Center in 2026. A quasi-experimental pretest-posttest …

30.08.2026journal-article

Journal of Gazi University Health Sciences Institute

Adherence of the Turkish Population's Dietary Pattern to the EAT-Lancet Planetary Health Diet Recommendations

Merve Esra Çıtar Dazıroğlu

The EAT-Lancet Planetary Health Diet (PHD) has emerged as a global dietary model that supports both human health and environmental sustainability within sustainable food systems. However, the evidence regarding adherence of the Turkish population to the PHD remains limited. This study evaluated adherence to the EAT-Lancet PHD among the Turkish population using the data from the Türkiye Nutrition and Health Survey (TNHS)-2017. EAT-Lancet reference values were adjusted according to the mean daily energy intake of eac …

30.08.2026journal-article

Journal of Gazi University Health Sciences Institute

Design, Synthesis, and Cholinesterase Inhibitory Evaluation of Novel 5-(Benzylthio)-1,3,4-thiadiazole Derivatives

Mahmut Gozelle, Burcu Kılıç

Alzheimer's disease remains one of the leading causes of dementia, and the development of novel cholinesterase inhibitors continues to attract considerable interest for symptomatic treatment. In this study, a series of five novel 5-(benzylthio)-1,3,4-thiadiazole derivatives bearing different nitrogen-containing substituents was designed, synthesized, and evaluated for their cholinesterase inhibitory activities. The target compounds were prepared through a straightforward synthetic route involving S-benzylation of 2 …

30.08.2026journal-article

Journal of Gazi University Health Sciences Institute

Solution-Focused Counseling in Nursing Practice

Hatice Tekin, Sultan Ayaz Alkaya

The necessity of addressing an individual’s psychosocial needs in addition to their physical care in the delivery of healthcare services has made the integration of counseling approaches into nursing care a priority. Solution-focused counseling is a short-term, structured approach that focuses on an individual’s strengths, available resources, and capacity to generate solutions rather than on their problems. This review examines the literature on the fundamental principles, techniques, and application of the soluti …

30.08.2026journal-article

Journal of Communication and Social Sciences

Dari Representasi Menuju Simulasi: Kesalehan Digital Haji Dan Umrah Di Instagram Dalam Perspektif Jean Baudrillard

Puput Aprilia Hermawati, Iqbal Muhamad Robani

ABSTRACT The digitalization of media has transformed how religious experiences are represented and interpreted in contemporary public spaces. In this context, Hajj and Umrah are no longer confined to sacred rituals but are increasingly produced, shared, and circulated through social media platforms. This study examines how Hajj and Umrah experiences are represented on Instagram and how such representations contribute to the construction of digital piety from the perspective of Jean Baudrillard. Employing a netnogra …

30.08.2026journal-article

Urologia Journal

Andrological emergencies in current emergency medicine: A narrative overview of clinical, psychological, and worldwide implications

Ghada Farouk Mohammed, Mohammed Saleh Al-Dhubaibi, Saleh Salem Bahaj, Ahmed Mohammed Al-Dhubaibi, Sameh Saad Aziz, Yasser Salem N. Saleh

Background: Andrological emergencies (AEs) constitute a critical subset of acute urogenital conditions requiring urgent recognition and intervention to preserve sexual and reproductive function while preventing long-term morbidity. Common AEs include testicular torsion, ischemic priapism, penile fracture, paraphimosis, Fournier’s gangrene, penile strangulation, and acute urinary retention. Aim: To provide a comprehensive synthesis of current knowledge on the clinical presentation, diagnostic approaches, therapeutic …

30.08.2026journal-article

Journal of Artificial Intelligence & Cloud Computing

Artificial Intelligence and Indigenous Language Revitalization: A Gadé Language Digitization Model

Obadiah GT

The marginalization of low-resource indigenous languages within contemporary Artificial Intelligence (AI) and Natural Language Processing (NLP) ecosystems poses a significant threat to global linguistic diversity and cultural heritage preservation. This study presents a comprehensive AI-driven Gadé Language Digitization Model designed to support the revitalization, preservation, and technological integration of the Gadé language of North-Central Nigeria. As a tone-rich Niger-Congo language characterized by complex …

30.08.2026journal-article

Uzbek Journal of Law and Digital Policy

The Impact of Digitalization Processes on the System of Legal Regulation of Labor Relations

Nikolay Kuryanov

This article examines how digitalization is transforming the system of legal regulation of labor relations, using Uzbekistan's labor legislation as a central case alongside comparative evidence from Russia, the European Union, France, Belgium, and the United States. Digitalization has produced two distinct forms of digital labor relations: the use of individual digital tools within otherwise traditional employment, such as electronic labor records, and the emergence of entirely new employment forms, such as remote …

30.08.2026journal-article

Frontiers on Healthcare Research

Inpatient Clinical Profile and Mortality Patterns at a Tertiary Referral Hospital in Indonesia: A Descriptive Study at RSUP Dr. M. Djamil Padang

Department of Statistics, Universitas Negeri Padang, Padang, Indonesia, Viora Antasya Viora, Dodi Vionanda Dodi, Dr. M. Djamil General Hospital, Padang, Indonesia, Alfitri Alfitri Alfitri

<p style="font-weight: 400;"><strong>Background:</strong> Hospital electronic medical records contain morbidity and mortality data that can be analyzed to provide a comprehensive picture of health profiles. However, most studies using inpatient data are limited in scope and do not integrate the distribution of diagnoses, mortality patterns, and case fatality rates into a single analytical framework. This study aimed to describe the characteristics of inpatients at Dr. M. Djamil General Hospital in Padang in 2025, i …

30.08.2026journal-article

International Journal of Health and Pharmaceutical (IJHP)

Evaluation of The Completeness of Electronic Medical Records In Supporting Reporting of The Top 10 Diseases of Inpatients At Majalengka Regional Hospital

Nova Oktaviani Rahayu, Intan Pujilestari

The completeness of Electronic Medical Records (EMR) is one of the important factors that determine the quality of health information and the accuracy of reporting the top 10 diseases in hospitals. This study aims to evaluate the completeness of the EMR in inpatients in supporting the reporting of the top 10 diseases at Majalengka Regional Hospital, identify the top 10 diseases, analyze EMR support for reporting, and identify factors that influence EMR incompleteness. The study used a mixed method with a quantitati …

30.08.2026journal-article

Scientific Reports

Clinical characteristics associated with failure to achieve a prespecified guideline-directed medical therapy target at discharge in patients with HFrEF undergoing scheduled hospitalization: a secondary analysis of the HEROES study

Agata Galas, Robert Morawiec, Iwona Gorczyca-Głowacka, Agata Tymińska, Katarzyna Byczkowska, Jarosław D. Kasprzak, Aleksander Siniarski, Marek Kuch, Beata Wożakowska-Kapłon, Adrian Stefański, Witold Furmanek, Paweł Krzesiński

Abstract Guideline-directed medical therapy (GDMT) is crucial for the pharmacological management of heart failure (HF) with reduced ejection fraction (HFrEF). The aim of the study was to identify clinical characteristics associated with failure to achieve the prespecified stringent GDMT target in patients with HFrEF undergoing scheduled hospitalization. The analysis included 287 patients with reduced left ventricular ejection fraction (LVEF), which is a subset of the 1422 participants of the HEROES study, a prospec …

30.08.2026journal-article

JHN: Journal of Health and Nursing

HUBUNGAN MODEL PEMBERDAYAAN KELUARGA BERBASIS HEALTH BELIEF MODEL (HBM) DENGAN PENCEGAHAN STUNTING PADA ANAK DI WILAYAH KERJA PUSKESMAS LABUAN KABUPATEN DONGGALA

Maharani Chikita, Fadli Fadli, Ekafadly Jusuf

Stunting remains a public health issue with far-reaching impacts on the quality of human resources. The prevalence of stunting in the Labuan Community Health Center (Puskesmas) working area reached 34.2%, well above the national average (19.8%) and that of Central Sulawesi Province (26.1%). This study aimed to determine the relationship between a family empowerment model based on the Health Belief Model (HBM) and stunting prevention behaviors. An observational analytic study with a cross-sectional design was conduc …

30.08.2026journal-article

International Journal of Academic and Industrial Research Innovations(IJAIRI)

Quantum Topological Neural Operators and Digital Twin Intelligence for Multiscale Climate, Energy, Hydrological, Urban, Industrial and Health Systems

Murali Krishna Pasupuleti

Abstract: Complex climate, energy, hydrological, urban, industrial and health systems are increasingly monitored through heterogeneous sensor, simulation and observational infrastructures, yet their digital twins remain fragmented by domain-specific models, incompatible scales and weak representations of nonlinear topology. This paper develops a unified model-based framework termed Quantum Topological Neural Operator Digital Twin Intelligence (QTNODT). The framework combines persistent and graph-topological represe …

30.08.2026journal-article

Scientific Reports

Heritability, pregnancy determination, and clinical follow-up in fetal copy number variation: an eight-year single-center retrospective study

Meiying Cai, Wenqi Chen, Meimei Fu, Liangpu Xu, Na Lin, Hailong Huang

Abstract Copy number variation (CNV) is defined as a > 1-kb-long DNA fragment copy number increase or decrease, with fetal CNV judgment and genetic counseling posing difficulties. We tested and retrospectively analyzed fetuses using chromosomal microarray analysis (CMA), 169 with abnormal CNV being completely verified and followed up for pregnancy and postnatal outcomes. Among the 169 fetuses, 103 and 66 exhibited inherited and de novo CNV. Of the former, 50, 34, and 19 displayed hereditary pathogenic CNV (P-CNV) [ …

30.08.2026journal-article

Malaysian Journal of Paediatrics and Child Health

Navigating the Challenges of Oesophageal Atresia With Tracheo-Oesophageal Fistula: A Case-Based Review From Diagnosis to Recovery

Harridas Manickam, Azliana Aziz, Mohd Shahrulsalam Mohd Shah

Oesophageal atresia with distal tracheo-oesophageal fistula (Type C EA/TEF) is the most common anatomical subtype of EA/TEF and requires early diagnosis and surgical management. Delayed recognition increases the risk of aspiration-related complications. This report describes the presentation, multidisciplinary management and early postoperative outcomes of two neonates with Type C EA/TEF treated at a tertiary referral centre. Two neonates presented after birth with respiratory distress, excessive oral secretions or …