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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
05.08.2026journal-article

Frontiers in Nutrition

Personalized nutrition for healthy aging: precision diets based on genomic, metabolic, and microbiome profiles

Claudia Reytor-González, Náthaly Mercedes Román-Galeano, Janeth Castano Jimenez, Oki Yonatan Oentiono, Washington A. Yoong, Martha Montalvan, Daniel Simancas-Racines

The global increase in life expectancy has been accompanied by a parallel rise in the burden of chronic diseases, many of which are influenced by diet and lifestyle. Conventional dietary guidelines, though broadly beneficial, often fail to account for the wide heterogeneity in nutritional needs, metabolic responses, and health trajectories observed among older adults. This limitation has spurred interest in personalized nutrition—a precision approach that leverages individual genomic, metabolomic, and gut microbiom …

05.08.2026journal-article

The EMBO Journal

P-selectin delineates conserved functional heterogeneity in early hematopoietic stem cell aging in humans and mice

Chong Yang, Tong Wang, Yue Chai, Lisha Wang, Yixuan Wang, Weili Wang, Fang Dong, Toshio Suda

Abstract Progressive aging of bone marrow hematopoietic stem cells (HSCs) underlies clonal hematopoiesis and age-associated hematologic disorders. Defining early molecular events driving HSC functional decline is essential for rejuvenation strategies. Here, we identify P-selectin (Selp) as a surface marker that stratifies HSCs into conserved functional and transcriptional states during organismal aging in humans and mice. P-selectin expression increases early during aging and remains elevated in old HSCs. Selp high …

05.08.2026journal-article

International Journal of Environmental Research and Public Health

Nutritional Status, Abdominal Obesity, and Predictors of BMI Categories Among Community-Dwelling Older Adults in Southern Thailand: A Cross-Sectional Study

Urai Jaraeprapal, Pornchanuch Chumpunuch, Arthit Boonrodchu, Uraiwan Pantong, Ladda Thiamwong

Geriatric nutritional problems are increasingly characterized by the co-existence of undernutrition and obesity, yet community-level evidence from Southern Thailand remains limited. Grounded in the social determinants of health (SDH) framework, this cross-sectional study examines the prevalence and independent predictors of BMI categories and abdominal obesity among 13,458 community-dwelling older adults across 20 sub-districts in Southern Thailand. Anthropometric measurements and structured interview data were ana …

05.08.2026journal-article

Frontiers in Public Health

Digital literacy and subjective well-being among Chinese older adults: the mediating role of social support

Hubin Ming, Mingxia Zhang, Xiaowei Wang, Yamin Yuan, Xichao Xia, Fengxia Wang

Objective This study aimed to investigate the current status of digital literacy, subjective well-being, and social support among older adults, analyze their interrelationships, and examine the mediating role of social support between digital literacy and subjective well-being. Methods A cross-sectional study was conducted from July to December 2025 using a multi-stage stratified random sampling method. A total of 1,260 older adults (aged ≥60 years) from six provinces in China were surveyed using the Digital Litera …

05.08.2026journal-article

Journal of Dementia and Alzheimer's Disease

Burden and Risk Factors of All-Cause Dementia in South Asia: An Analysis of Global Health Data and a Framework for Future Dementia Longitudinal Studies in Low-Resource Settings

Dushani L. Palliyaguru, Nipuni Palliyaguru, Camila Vieira Ligo Teixeira, Nicole M. Armstrong, Sanka Liyanage, Upul Senarath, Carukshi Arambepola, Saroj Jayasinghe, Chamila Dalpatadu

Background: Dysregulated brain aging leads to dementia in some older adults. South Asia is one of the most populous regions of the world with a rapidly growing older adult population. Yet, very few studies have focused on quantifying the status and risk factors driving aging-related conditions such as dementia in this part of the world. Objectives: We explored multiple sources of global health data to quantify and compare all-cause dementia indices in South Asian countries. Design: Afghanistan, Bangladesh, Bhutan, …

06.08.2026journal-article

The Gerontologist

Intergenerational homesharing between older adults and university students: a scoping review

Alison Craswell, Karen Watson, Tamara Sysak, Kristen Tulloch, Apil Gurung, Susanna Curry, Daniel P Wadsworth

Abstract Background and Objectives Housing needs for older people wishing to age in place and university students are different, yet both groups face unmet needs. To support older adults to remain in their homes longer, many countries have policies for aging in place with in-home support. Housing affordability, a growing issue globally, leaves older adults and students vulnerable to homelessness or precarious housing. This scoping review aimed to explore the concept of intergenerational homesharing, where older adu …

05.08.2026journal-article

The Gerontologist

Social connection and disconnection: Older adults’ life course perspectives on information and communication technologies

Laura Hurd, Catherine Tran, Erika Delorme, Erica V Bennett, W Ben Mortenson

Abstract Background and Objectives Research has established that while most older adults use information and communication technologies (ICTs), loneliness and social isolation in later life is a pressing issue. Studies of older adults’ ICT use has largely been cross-sectional, focused on their attitudes and preferences, and conducted with white, well-educated individuals who were disproportionately aged 65 to 75. Using an intersectional life course perspective, the purpose of our study was to understand the meaning …

05.08.2026journal-article

BMC Health Services Research

What is required for digital care and support technologies to be experienced as good care by community-dwelling older adults? A qualitative study

Kasper Kruithof, Vivianne Dörenberg, Brenda Frederiks

Abstract Background Digital care and support technologies may support independent and healthy aging, and are promoted as means to reduce healthcare costs and improve access. Yet realizing this potential in practice remains challenging, particularly given the variability in how older persons experience these technologies. Therefore, to better understand their perceived value and, indirectly, support efficient and equitable elderly care, we explored what is required for such technologies to be experienced as good car …

05.08.2026journal-article

Avicenna Journal of Medical Biotechnology

Modulation of NF-κB, MMP-1, and HAase by Coriandrum sativum Seed Extract in UV-Induced Skin Aging Model

Meilinah Hidayat, Wahyu Widowati, Mariska Elisabeth, Anindita Putri Distya, Hanna Sari Widya Kusuma

ackground: Coriandrum sativum L. (coriander) contains abundant flavonoids and phenolic compounds that contribute substantially to its antioxidant capacity. These constituents exhibit strong free radical–scavenging activity, offering protection against cellular damage and premature skin aging, particularly under Ultraviolet (UV) exposure. This study evaluated the anti-aging effects of Coriander Seed Extract (CSE) in an in vitro UVB-induced photoaging model using human dermal fibroblasts (BJ cells). Methods: CSE was …

05.08.2026journal-article

Health and Quality of Life Outcomes

Health literacy and health outcomes among older adults in Korea: a secondary analysis of 2023 KNHANES data

Hyunjeong Kwon, Eunhee Lee, Shin-Ae Kim, Jinhee Park, Jayun Kim

Abstract Background Population aging has increased the prevalence of chronic diseases among older adults and increased the need for effective health information use. However, evidence regarding how health literacy is associated with health outcomes among older adults, and whether this association varies by chronic disease status, remains limited. Accordingly, this Korean study was conducted to evaluate the association between health literacy and health-related quality of life (HRQoL) and subjective health status am …

05.08.2026journal-article

Revista Interdisciplinar de Estudos em Saúde

Considerações sobre o envelhecimento de profissionais da segurança pública brasileira

Dante Ogassavara, Thais Silva-Ferreira, Jeniffer Ferreira-Costa, Ivan Wallan Tertuliano, Daniel Bartholomeu, José Maria Montiel

Em determinadas atuações profissionais, há maiores aspectos de insalubridade. A atuação dos profissionais de segurança pública envolve diversos fatores implicantes à saúde e, quando se considera o processo de envelhecer, evidencia-se a importância de compreender as variáveis envolvidas e geradas nesse contexto. Este estudo teve como objetivo compilar conhecimentos relativos aos aspectos envolvidos na atuação profissional na segurança pública e suas repercussões no processo de envelhecimento desses profissionais. Pa …

05.08.2026journal-article

Frontiers in Cellular and Infection Microbiology

Host–virus resilience networks and viral inflammaging circuits in aging and long COVID: a CMV-centered perspective

Ludmila Müller, Svetlana Di Benedetto, Viktor Müller

Aging and long COVID are increasingly recognized as states of disrupted host homeostasis characterized by chronic inflammation, immune remodeling, metabolic dysfunction, and impaired stress adaptation. These alterations may compromise the mechanisms that normally maintain viral latency, thereby increasing susceptibility to reactivation of persistent viruses such as Cytomegalovirus (CMV). In this mini-review, we propose a systems-level framework in which latent viral reactivation emerges as a manifestation of declin …

05.08.2026journal-article

OTJR: Occupational Therapy Journal of Research

Effects of Ageism, Depression, Physical Resilience, and Frailty on Quality of Life Among Older Women

Yen-Chun Wang, Yi-Jung Chen, Chieh-Hsiu Liu, Kah Ying Yap, Yi-Ching Yang, Mark D. Griffiths, Ming-Ta Hsieh, Chung-Ying Lin

In Taiwan, as a super-aging society, older women face unique challenges that affect their health and quality of life (QoL). The present 1-year longitudinal study was conducted to examine changes in physical and psychosocial health and the relationship between these factors and QoL from March 2023 to June 2024. Women ( N = 114) aged over 60 years completed baseline assessments, which included demographic information and evaluations using standardized scales, and 48 completed the follow-ups conducted 1 year later. Fi …

05.08.2026journal-article

Biomedicines

Profile of People Living with HIV Switching Prior Antiretroviral Treatment to a Doravirine-Based Regimen in the Real-World Clinical Setting in Greece: The Retrospective DORAVITO Study

Antonios Papadopoulos, Myrto Astriti, Vasileios Papastamopoulos, Vassileios Paparizos, Helen Sambatakou, Symeon Metallidis, Konstantinos Protopapas, Charalampos Moschopoulos, Georgios Adamis, Panagiota Lourida, Charisis Totsikas, Varvara Vasalou, Theofilos Chrysanthidis, Panagiotis Kollaras, Eleni Boutselakou, Dimitris Tsokos, Georgios Trimis, Lazaros Poughias

Background: Doravirine (DOR) is a new-generation non-nucleoside reverse transcriptase inhibitor, which has emerged as an option for people living with HIV (PLWH) owing to its favorable efficacy and safety profile, unique resistance pathway and limited potential for drug-drug interactions. Methods: This retrospective chart review study aimed to better understand DOR-based treatment use in Greece, PLWH characteristics, and drivers of treatment switch. Eligible individuals were adult PLWH who were switched to a DOR-ba …

05.08.2026journal-article

Social Sciences

“Everyone’s Moving, and Learning Together”: Young People and Practitioners Working with Collective Care to Create Futures Without Gender-Based Violence

Lena Molnar, Sarah McCook

Gender-based violence may be considered a failure or absence of care across the interpersonal, symbolic, and structural levels. Feminist scholars have called for closer attention to an ethic of care as one vital pathway to shared solidarity for social justice and relations of non-violence. Works from Black, Indigenous, queer and disability writers and activists have similarly illustrated the transformative potential of collective care for building community and ending systems of oppression. In this paper, we draw o …

05.08.2026journal-article

Sociological Research Online

“Here, I Have My Neighbors”: Social capital, welfare, and aging-in-place among older migrant women

Ferhan S. Palaz, Ulaş Sunata

Aging-in-place is a central concept in gerontology, yet its underlying assumptions about family support, territorial stability, and care provision are increasingly challenged in contexts of migration. This study examines how aging-in-place is constructed through social capital and welfare structures among older migrant women living alone. Drawing on in-depth interviews with eight widowed migrant women aged 65 and older residing in Germany and the Netherlands, the article adopts a life-course and transnational persp …

05.08.2026journal-article

Life

Midlife Vascular and Lifestyle Determinants of Late-Life Cognitive Decline and Dementia: A Life-Course Prevention Framework with a Gulf (GCC) Perspective

Najeeb Qadi, Amaal Aldakheel, Eslam Shosha

Dementia is a growing global health challenge, yet many determinants of late-life cognitive decline emerge decades before symptoms appear. Midlife is a practical window for prevention because hypertension, diabetes, obesity, dyslipidemia, smoking, physical inactivity, unhealthy diet, sleep disturbance, and social isolation can be identified and modified before substantial brain injury becomes apparent. This narrative review synthesizes evidence linking midlife vascular and lifestyle exposures to late-life cognitive …

05.08.2026journal-article

European Review of Aging and Physical Activity

Real-world walking and activity patterns in community-dwelling older adults: a cross-sectional analysis of baseline data from the SMART-AGE trial

Tobias Eckert, Katharina Gordt-Oesterwind, Ann-Sophie Haas, Melissa J. Boettinger, Anna-Lena Schubert, Meike Snijder-Steinhilber, Hans-Werner Wahl, Juergen M. Bauer, Jochen Klenk, Jose Albites–Sanabria, Clemens Becker, Carl-Philipp Jansen

Abstract Background Digital mobility outcomes (DMOs) measured under real-world conditions allow for differentiated insights into mobility patterns of older adults. This study provides an advanced description of real-world walking in community-dwelling older adults and identifies correlates of walking amount, pattern and speed. Methods This cross-sectional study used baseline data from the SMART-AGE intervention trial with community-dwelling older adults (age ≥ 67 years). Assessment procedures included one-week moni …

05.08.2026journal-article

Frontiers in Aging Neuroscience

Hearing technology and the brain: cognitive function in different hearing device users

Bamini Gopinath, Jessica Turner, George Burlutsky, Shermin Lim, Alicia Zou, Ghazal Shineh, Kerry Sherman, Kompal Sinha, Diana Tang

Background There is an evidence-gap on how different hearing devices influence cognition. This study aimed to simultaneously compare cognitive performance across key domains among hearing aid, cochlear implant and bimodal device users. Methods Cross-sectional data were collected and analyzed as part of the Hearing Impairment in Adults: A Longitudinal Outcomes Study, during 2022–24. Adults aged ≥40 years old using hearing aids, cochlear implants, or bimodal hearing devices were recruited. Of 1054 approached, 617 par …

05.08.2026journal-article

Research on Aging

The Adverse Consequences of Material Hardship for Mattering in Later-Life

Alex Bierman, Fahimeh Mehrabi, Yeonjung Lee

We examine whether material hardship has adverse consequences for older adults’ mattering, and further consider this association in the context of the quality and quantity of older adults’ social interactions. Random- and fixed-effects models estimated using structural equation modeling examine the association between material hardship and mattering in a nationally representative longitudinal survey ( N = 4,009) of older Canadians. Even after taking unobserved time-stable sources of spuriousness into account, mater …

05.08.2026journal-article

European Geriatric Medicine

From memory clinics to Brain Health Services: implications for older adults and the future of cognitive care in Europe

T. J. Welsh, Y. Chen, S. P. Kennelly, T. J. Quinn, D. Religa, S. D. Shenkin, P. Soysal, H. M. Roitto

Abstract Aim To explore the implications of transitioning from traditional memory clinics to Brain Health Services (BHS) for older adults, and to advocate for a geriatric-informed, equitable, and function-oriented approach to brain health care. Methods This perspective article draws on discussions within the EuGMS Brain Health and Dementia Specialist Interest Group and relevant literature to examine the implications of emerging Brain Health Services for older adults. Results The emergence of Brain Health Services r …

05.08.2026journal-article

Jurnal Tata Rias

PENGGUNAAN TEKNIK MAKEUP GAYA KOREA PADA TATA RIAS WAJAH GERIATRI

Chelsea Hexa Widiasmara, Nia Kusstianti, Sri Dwiyanti, M.A. Hanny Ferry Fernanda

Penelitian ini bertujuan untuk mengetahui hasil tata rias wajah geriatri dengan menggunakan teknik makeup gaya Korea serta kualitas hasil rias ditinjau dari kemampuan penyamaran kerutan. Penelitian ini menggunakan metode deskriptif kuantitatif dengan desain one shot case study. Subjek penelitian adalah satu orang wanita geriatri berusia di atas 45 tahun dengan kondisi kulit wajah yang menunjukkan tanda-tanda penuaan. Teknik pengumpulan data dilakukan melalui observasi dan penilaian oleh tiga orang observer yang mem …

05.08.2026journal-article

Anales de la Academia Hispanoamericana de Doctores

Alimentación, estilos de vida y procesos de envejecimiento

Javier Aranceta Bartrina

The article analyzes the relationship between nutrition, lifestyles and the aging process, highlighting the importance of a balanced and adapted diet for the elderly. It points out that, although they require less energy, they need specific nutrients such as calcium, vitamin D and antioxidants. He proposes a food pyramid adapted to people over 70, with emphasis on vegetable proteins, complex carbohydrates and healthy fats, as well as recommending physical activity and nutritional supplements under medical supervisi …

05.08.2026journal-article

International Journal of Molecular Sciences

Convergent Gut Microbiome Remodeling Across Ischemic Stroke, Myocardial Infarction, and Longevity Reveals a Shared Ecological Signature of Aging and Disease

Chuisheng Zeng, Jianfang Chen, Xuetong Yong, Yongfang Xie

Gut microbiota dysbiosis has been associated with ischemic stroke (IS), myocardial infarction (MI), and aging, but whether these contexts share reproducible microbial features remains unclear. We conducted an exploratory and hypothesis-generating descriptive study of genus-level microbiota patterns across an internal IS cohort and publicly available external IS, MI, and age-stratified or longevity-associated datasets. Analyses were performed within predefined age strata and interpreted cautiously because of the sma …