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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
29.08.2026journal-article

The International Journal of Medical Robotics and Computer Assisted Surgery

Efficacy and Safety Analysis of Single‐Port Robotic Assisted Cholecystectomy Using a Novel Surgical Platform: A Bicentre, Single‐Arm, Prospective Phase II Clinical Study

Chao Jing, Kun Liu, Guowei Zhang, Hongwei Wu, Zhe Jia, Guoxin Li, Yaping Zhao, Zhongtao Zhang, Wei Guo

ABSTRACT Background Single‐port robotic cholecystectomy offers minimally invasive benefits. This trial evaluated the feasibility and safety of a novel system, MicroPort SA‐1000. Methods In this dual centre, single‐arm, prospective study, eligible patients underwent single‐port robot‐assisted cholecystectomy with MicroPort SA‐1000. The primary endpoint was the completion rate, while secondary endpoints included estimated blood loss, operating time, hospital length of stay and complications. Results From June 2023 to …

29.08.2026journal-article

Journal of Ayurvedic Herbal and Integrative Medicine

CARIES REMINERALIZATION THERAPY – AN IN VITRO EVALUATION OF THE EFFICACY OF THREE REMINERALIZING AGENTS BY SEM AND EDS ANALYSIS

Geeta IB, Pranjul Sharma, Rayala Lokesh, Urvashi Patel

Dental caries, by definition, is one of the most common diseases worldwide. It is dependent on biofilm, diet, and other factors. It causes mineral loss, disrupting the balance between demineralization and remineralization. This has led to the development of various treatment approaches for initial carious lesions. Remineralization requires a natural pathway to restore the mineral loss of hydroxyapatite (HAP) crystals. Many materials have been clinically evaluated and have demonstrated promising results.

29.08.2026journal-article

Healthcare

Artificial Intelligence in Prehospital Tele-Emergency Medicine: A Survey of Acceptance and Attitudes

Nadezhda Durdova, Mathias Schmidt, Hanna Schröder, Pia Thoma, Dominik Groß, Saskia Wilhelmy

Background/Objectives: Artificial intelligence (AI) is increasingly being used in medicine to improve the efficiency, accuracy, and timeliness of patient care. In prehospital tele-emergency medicine, AI also has the potential to address various challenges and support tele-emergency physicians. This study focuses on a specific AI-based decision support system being developed for use by practitioners. While technical feasibility is a prerequisite for the successful implementation of this system, social, ethical, and …

29.08.2026journal-article

The Nursing Scope

Occupational Stress and Nursing Performance in In-Patient Care: Organizational Determinants in a Nigerian Tertiary Hospital

Abiodun FATUKASI

Background: Occupational stress remains a major challenge in nursing practice, particularly in inpatient care settings characterized by demanding workloads, complex clinical responsibilities, and resource constraints. Persistent workplace stress can adversely affect nurses’ performance, clinical decision-making, communication, and patient safety. Despite growing concerns about occupational stress among nurses, evidence regarding its organizational determinants and impact on nursing performance in Nigerian tertiary …

29.08.2026journal-article

Cancers

Comprehensive Genomic Profiling Reveals the Mutational Spectrum and Clinical Significance of BRCA1/2 and Other Cancer-Susceptibility Genes in Breast Cancer Patients from Southern Tunisia

Nihel Ammous-Boukhris, Rania Abdelmaksoud-Dammak, Wala Ben Kridis, Dorra Ben-Ayed-Guerfali, Souhir Guidara, Ameni Feki, Hassen Kamoun, Afef Khanfir, Jamel Daoud, Gérard-Hubert Lizard, Ali Gargouri, Raja Mokdad-Gargouri

Background/Objectives: This study aims to investigate the mutational spectrum of BRCA1 and BRCA2 genes in a cohort of breast cancer (BC) patients from southern Tunisia, and to evaluate their clinical and prognostic significance. Additionally, this study explores the contribution of other cancer predisposition genes and the prevalence of variants of uncertain significance (VUS). Results: Among the 165 patients included, pathogenic or likely pathogenic variants (P/LPVs) in BRCA1/BRCA2 were identified in 19 cases (11. …

29.08.2026journal-article

Journal of Separation Science

Bridging the Gap Between Chemiluminescence Immunoassay and Liquid Chromatography‐Tandem Mass Spectrometry for Infliximab Monitoring: Method Validation and Clinical Comparability Study

Ying Xia, Ming‐Mei Zhu, Meng‐Qing Xiao, Chen‐Chun Zhong, Yu‐Jun Zhou, Yi‐Hao Xue, Shi‐Wei Zheng, Li Li, Feng Chen

ABSTRACT Infliximab (IFX) is a cornerstone biologic for pediatric inflammatory bowel disease, where therapeutic drug monitoring (TDM) is essential but complicated by inter‐platform variability. Systematic comparison of automated immunoassays with reference methods is therefore warranted. This study aimed to validate an in‐house chemiluminescence immunoassay (CLIA) for IFX quantification and evaluate its agreement with liquid chromatography‐tandem mass spectrometry (LC‐MS/MS). A CLIA kit was validated by assessing t …

29.08.2026journal-article

Journal of Clinical Medicine

Nocturnal Autonomic Dysregulation and Admission-Window Clinical Suicide-Risk Assessment in Hospitalized Children and Adolescents

Qiyuan Cao, Jiaqi Xu, Wenjing Li, Yan Zhang, Xuehua Huang, Kexin Zhou, Jinquan Zhang, Lijun Jiang

Background/Objectives: Suicide-risk assessment during child and adolescent psychiatric hospitalization draws on patient report, clinical history, and professional observation. Whether nocturnal autonomic physiology is concurrently associated with a structured admission-window assessment after accounting for depressive symptoms and self-reported suicidal ideation remains uncertain. Methods: We analyzed 212 hospitalized children and adolescents receiving inpatient care for a major depressive episode. All had a Nurses …

29.08.2026journal-article

Eurasian Journal of Anesthesiology and Intensive Care

Antibacterial effects of levobupivacaine against staphylococcus aureus in a patient-controlled epidural analgesia model: an in vitro experimental study

Gülay Akıncı

Aims: Catheter-related infections remain an important complication of epidural analgesia. Local anesthetics may contribute to infection prevention because of their antimicrobial properties. This study aimed to evaluate the antibacterial effects of clinically relevant concentrations of levobupivacaine against Staphylococcus aureus in a simulated patient-controlled epidural analgesia (PCEA) model. Methods: An in vitro experimental PCEA infusion system was established using epidural catheter tubing and 0.2-µm bacteria …

29.08.2026journal-article

Journal of the Pediatric Infectious Diseases Society

Neonatal Infectious Harm Reduction Benefits of Maternal Substance Use Treatment: A Dyad-Based Retrospective Review

Lindsey E Hastings, Ellen F Eaton, Rachel G Sinkey, Claudette L Poole

Abstract Background Substance use disorders (SUD) in pregnancy can disrupt routine prenatal care and have been linked to increased risk of congenital syphilis as well as perinatal exposure to hepatitis C (HCV) and human immunodeficiency virus (HIV). Moreover, inconsistent adherence to universal HCV maternal screening recommendations, fragmented care, and frequent removal of infants for child welfare often make timely identification of maternal HCV or syphilis infection challenging and follow-up screening of exposed …

29.08.2026journal-article

Psychiatry and Clinical Neurosciences

Brain Network Convergence of Abnormal Gray Matter and Functional Activity of Pathological Dissociative Symptoms

Xuhan Cui, Leyi Zhang, Yangpan Ou, Yong Liu, Bing Lang, Wenbin Guo

Aim Pathological dissociation is a complex clinical symptom widely observed across various psychiatric disorders. Dissociative symptoms prolong the duration of hospitalization and are associated with a poor clinical prognosis. Although several pathological models (e.g., the frontal‐limbic overmodulation model and the defense cascade model) have been proposed to interpret dissociative symptoms, heterogeneous regional‐level imaging findings impede our comprehension of the neural changes underlying dissociative sympto …

29.08.2026journal-article

Journal of Feline Medicine and Surgery Open Reports

EXPRESS: Surgical management of bilateral atypical tibial fractures associated with long-term bisphosphonate therapy in a cat

Justin Koh Wei Wong, Stephanie Colthurst

An eight-year-old, indoor, male neutered Oriental mix cat was presented with acute bilateral pelvic limb lameness without preceding trauma. The cat had received oral alendronate for 4.5 years for the management of idiopathic hypercalcaemia. Radiographs revealed bilateral, closed, comminuted proximal tibial and fibular fractures with cortical sclerosis. Staged bilateral open reduction and internal fixation were performed using orthogonal locking compression plates. Alendronate therapy was discontinued, and the cat r …

29.08.2026journal-article

ACR Open Rheumatology

Reduction of CXCR3 + CCR6 + CD4 + T Cells and IL ‐17+ RORγt + CD4 + T Cells During Secukinumab Treatment Identifies Patients With Axial Spondyloarthritis Responsive to Subsequent Biologic Therapy

Addison Pacheco, Patricia Remalante‐Rayco, Nigil Haroon, Denis Poddubnyy, Robert D. Inman

Objective We recently reported an immune profile that stratifies patients with axial spondyloarthritis based on clinical response to secukinumab. We now undertake an exploratory study on the secukinumab nonresponder patients to determine if immunologic changes occur during their initial secukinumab treatment that could determine their next biologic response. Methods At the clinician's discretion, 18 patients who did not respond to secukinumab were either switched to a tumor necrosis factor inhibitor (TNFi; n = 8) o …

29.08.2026journal-article

EJNMMI Physics

Development of a multifunctional anthropomorphic phantom for performance evaluation in nuclear medicine imaging: preliminary PET/CT validation

Xuesong Su, Zuowei Zou, Yingmao Chen, Hao Hong, Zhiwen Chen, Xuejuan Wang, Jianhua Geng

Abstract Purpose To develop an anthropomorphic phantom that enables the simultaneous evaluation of key performance metrics for nuclear medicine imaging systems and to preliminarily validate its application in PET/CT. Methods The anthropomorphic phantom replicates thoracic and abdominal anatomy, simulating human skeletal structures, lung tissue, soft tissue, and tumors. The phantom is divided into five functional regions: a lung tumor detection region (right lung with spheres), an attenuation and scatter correction …

29.08.2026journal-article

Indian Journal of Radiology and Imaging

Prenatal Diagnosis of Thanatophoric Dysplasia Type I Based on Classical Ultrasound Findings During Anomaly Scan: A Case Report

Rajat Garg, Rashmi Singh

Abstract Thanatophoric dysplasia (TD), the most common lethal skeletal dysplasia, results from FGFR3 mutations causing impaired endochondral ossification. Where molecular testing is unavailable, ultrasound evaluation is the diagnostic cornerstone. We report a 24-year-old primigravida undergoing a routine anomaly scan at 22 weeks. Ultrasonography showed severe micromelia with femoral bowing (telephone-receiver appearance), a markedly narrow thoracic cage (thoracic circumference of 11.79 cm, falling below the fifth p …

29.08.2026journal-article

Journal of Clinical Medicine

The “Namaste Sign”—A Novel Coronal MRI Marker for the Evaluation of Anterior Cruciate Ligament Integrity

Shashank Chapala, Rajesh Botchu, Hasaam Uldin, Meili Jade Temsin Leung Chew, Kapil Shirodkar, Sang Bum Lee, Anoop Venkatapura Bylaswamy, Avneesh Chhabra

Magnetic resonance imaging (MRI) is universally recognized as the gold standard for evaluating anterior cruciate ligament (ACL) injuries. However, differentiating partial tears from complete ruptures using the standard sagittal plane remains a diagnostic challenge. The oblique coronal orientation of the ACL often leads to volume averaging artifacts and inaccurate interpretations. While axial imaging offers a favorable alternative, distal tears near the tibial attachment are frequently missed. This review synthesize …

29.08.2026journal-article

Journal of Clinical Medicine

Prospective Assessment of Carboxyhemoglobin and Methemoglobin Levels in Operating Room Personnel During HIPEC/Peritonectomy Compared with Standard Colorectal Surgery

Emil Kinda, Petar Matosevic, Sanda Smud Orehovec, Ivan Romic, Rudolf Radojkovic, Branko Bogdanic

Background/Objectives: In the operating room, surgical staff are exposed to inhalation of smoke from the combustion of tissues when using electrocautery. By introducing HIPEC/peritonectomy in the treatment of malignant neoplasms of the peritoneum, exposure to smoke is significantly increased. To adequately perform this procedure, high-power monopolar cautery is used. The aim of this study was to assess carbon monoxide exposure associated with surgical smoke generated during peritonectomy procedures and to compare i …

29.08.2026journal-article

Obesity Surgery

Weighed Down by Paperwork: Identifying Barriers to Metabolic and Bariatric Surgery Evaluation in the United States

Rylee Barber, Stephen Moorhead, Kalina Siehl, Ronit Pathak, Mary K Bryant

Abstract Background Obesity affects over 42% of U.S. adults, yet access to metabolic and bariatric surgery (MBS) remains limited despite its proven efficacy. While use of GLP-1 receptor agonists has risen in the past three years, MBS volume has declined over 25% during the same period. Reported barriers to MBS include long wait times, societal sigma, fear of surgery, and insurance restrictions. This study investigated appointment accessibility and program requirements for patients seeking MBS. Methods We conducted …

29.08.2026journal-article

JAMA

LDL Cholesterol Lowering With Evolocumab Before Percutaneous Coronary Intervention for Acute Myocardial Infarction

Gilles Montalescot, Emile Ferrari, Géraud Souteyrand, Claire Bouleti, Grégoire Range, Laure Batias-Moreau, Marco Chioccioli, Andrea Picchi, Jean-Guillaume Dillinger, Giovanni Esposito, Giuseppe Patti, Flavien Vincent, Nassim Braik, Stéphane Ederhy, Pierre Coste, Sinda Hannachi, Nassim Redjimi, Michel Zeitouni, Benjamin Duband, Etienne Fourrier, Paul Guedeney, Niki Procopi, Pierre Sabouret, Abdourahmane Diallo, Karine Brochard, Amel Chamam, Nicolas Vignolles, Mathieu Kerneis, Johanne Silvain, J. Wouter Jukema, François Mach, Angel Cequier-Fillat, Holger Thiele, Stanislaw Bartus, Leonardo Bolognese, Eric Vicaut, AMUNDSEN Investigators of the ACTION Study Group, Denis Angoulvant, Anne Bellemain-Appaix, Farzin Beygui

Importance Proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibition is recommended as second- or third-line lipid-lowering therapy after myocardial infarction (MI), resulting in prolonged periods of inadequate low-density lipoprotein cholesterol (LDL-C) control. Whether in–catheterization laboratory decision of PCSK9 inhibition, started before mechanical reperfusion, could improve LDL-C control and clinical outcomes at 1 year is unknown. Objective To evaluate evolocumab as first-line therapy vs standard car …

29.08.2026journal-article

International Journal of Prognostics and Health Management

Multiscale Ordinal Complexity Analysis for Wind Turbine Bearing Fault Diagnosis

Paulo R. L. Almeida, Thyago L. V. Lima, Alisson V. Brito, Abel C. Lima Filho

Permutation-entropy methods for bearing fault diagnosis in wind turbines are typically validated on laboratory test rigs without enforcing specimen-level separation in cross-validation or quantifying axis-specific diagnostic contributions. This study addresses these limitations using the Fraunhofer LBF operational wind turbine bearing dataset, applying multiscale permutation entropy (MPE) to triaxial front-bearing accelerometer signals across 44 bearing specimens (18 healthy, 10 inner race, 4 outer race, 12 roller …

29.08.2026journal-article

Pharmaceuticals

Trimetazidine in Chronic Coronary Syndrome and Coronary Artery Disease: A Narrative Review of Clinical Efficacy, Safety, and Current Guideline Position

Daniel Miron Brie, Cristian Mornoș, Alexandru Tîrziu, Roxana Popescu, Alina Diduța Brie

Background: Chronic coronary syndrome (CCS) is a major source of morbidity and healthcare utilization, and a substantial proportion of patients continue to experience angina despite contemporary revascularization and guideline-directed medical therapy. Trimetazidine, a metabolic anti-ischemic agent that does not affect heart rate or blood pressure, has been used for decades as a non-hemodynamic add-on. Its position in international guidelines, however, has shifted. We aimed to synthesize current evidence on the cli …

29.08.2026journal-article

Farabi Tıp Dergisi

Awake Tracheal Intubation Practice and Clinical Decision-Making in Brief Airway Scenarios Among Anesthesiologists in Türkiye: A Cross-Sectional Survey

Engin Çetin, Ahmet Yuksek

Objective: Awake tracheal intubation (ATI) is recommended for an anticipated difficult airway, yet its use remains limited. This study evaluated anesthesiologists’ ATI practices and scenario-based decision-making and identified factors associated with its use.Material and Methods: This cross-sectional, convenience-sampled online survey was conducted in Türkiye (13 March–13 April 2026). Anesthesiology residents and specialists completed an anonymous questionnaire covering demographics, three brief clinical scenarios …

29.08.2026journal-article

Advanced Materials

Switching Peroxymonosulfate Redox Routes by Manipulating Spinel Tetrahedral and Octahedral Site Activity for Multi‐Scenario Wastewater Treatment

Zhiyong Zhao, Yuanyuan Lv, Jiachen Zhang, Shuai Yue, Mengxue Yang, Yanxiao Li, Weitao Liu, Pengfei Wang, Sihui Zhan

ABSTRACT For diverse wastewater treatment scenarios, achieving controllable switching of reactive oxygen species within a unified catalytic system remains a major challenge. Here, an inert cation substitution strategy is proposed to regulate tetrahedral and octahedral Co activity in Co 3 O 4 , enabling controllable switching between radical and nonradical pathways. Octahedral‐Co‐enriched ZnCo 2 O 4 (ZCO) selectively directs peroxymonosulfate (PMS) activation toward the 1 O 2 pathway (95.8% contribution), whereas te …

29.08.2026journal-article

Journal of Trauma Anaesthesia, Resuscitation and Critical Care

Airway Management in a Patient with Extensive Maxillofacial Trauma: A Case Report

Abhishek Nagarajappa, Deepak Shanker S., Reshma Kalagara, Christopher Dass

Managing the airway in patients with severe maxillofacial trauma remains one of the most demanding challenges in trauma care. Facial fractures not only distort normal anatomy but can also lead to airway obstruction, bleeding, aspiration risk, and difficulty in ventilation and intubation. Effective airway management in these cases depends on rapid decision-making, readiness for alternative airway techniques, and close coordination between the anesthesiologist and surgeon. A well-planned, individualized approach is e …

29.08.2026journal-article

Translational Medicine

Translational medicine in abdominal military field surgery: from innovations to standards of care for abdominal gunshot wounds

V. A. Syusyura, R. I. Plishchuk, M. M. Magomedov, A. V. Pirogov, A. N. Kazantsev

The high mortality rate of abdominal gunshot wounds (15–60 %), rising antibiotic resistance, and the need for accelerated innovation necessitate a systematic analysis of current approaches to diagnostics, surgical tactics, and translational medicine in military field surgery. The objective of this review is to develop a comprehensive scientific and practical paradigm for abdominal military field surgery that integrates epistemological, translational, and prognostic aspects. The methodology included searching the Ru …