Frag' FlorenceEvidenz. Klar. Anwendbar.
Uhr 7/8Sources Journal Tree
Easy Demo

Florence Themenbrowser · Alle Themen · Seite 116

Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

Themen erkunden

Aktuelle Forschung nach Fachgebiet

24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
31.08.2026journal-article

World Journal of Advanced Research and Reviews

Social determinants of health and health inequalities in Alzheimer's Disease in the United Kingdom: A Systematic Review of the Evidence between 2018 and 2024

Oluwabisifunmi Joshua Egwaoje

Background: Alzheimer's disease (AD) accounts for 60–70% of dementia cases worldwide and remains a leading cause of death in England and Wales (Leahy et al., 2023; WHO, 2021). Its prevalence, progression and management are shaped not only by biological ageing but also by health inequalities and the social determinants of health (SDoH), yet the mechanisms linking these factors to AD outcomes in the UK remain fragmented across the literature. Aim: This systematic review synthesises evidence on how health inequalities …

31.08.2026journal-article

World Journal of Advanced Research and Reviews

ENHANCING MENTAL HEALTH ACCESS: A TELEHEALTH APPROACH FOR RURAL YOUNG ADULTS

Christy Ugo Peters

The rural young adults between 18 and 25 years are still among the most underserved groups in the systems of global mental health with compounded stigma, provider shortages, geographic isolation, and limited digital infrastructure. The literature review will focus on the importance of telehealth as a tool of increasing access to mental health among this population based on five empirical studies published between the years 2020 and 2024. The study was a synthesis of evidence on qualitative, quantitative, mixed-meth …

31.08.2026journal-article

World Journal of Advanced Research and Reviews

THE ASSOCIATION BETWEEN STRESS MANAGEMENT AND EMOTIONAL WELL-BEING AMONG NURSING STAFF IN SAUDI ARABIA'S MAKKAH HEALTH CLUSTER

Reem Hamzah Alshotiri, Hafizah Che Hassan

Stress has been among the most widespread occupational risks among nurses, especially in high-demanding healthcare environments like the Makkah Health Cluster in Saudi Arabia. Persistent stress has an adverse effect on emotional health resulting in burnout, decreased job satisfaction, and low-quality patient care. This following systematic review aimed to address the following question: What is the association between stress management interventions and emotional well-being among nursing staff in the Makkah Health …

31.08.2026journal-article

Open Research Africa

Digital communication for maternal and newborn health in sub-Saharan Africa: evidence, implementation and AI implications

Richard Kimera, Emily Downey, Rogers Mwavu, David Bamutura, Liam McCoy, Jospeh Ngonzi, William Wasswa, Leo Anthony Celi, Fred Kaggwa

Digital health interventions are increasingly used to communicate antenatal, intrapartum, postnatal and newborn-care information in sub-Saharan Africa, but their effects depend on more than message delivery. This narrative review examines what recent evidence shows about the mechanisms, implementation conditions and outcomes of patient-facing and provider-facing digital interventions, with particular attention to rural and semi-rural settings. Peer-reviewed studies and authoritative guidance published from 2000 to …

31.08.2026journal-article

LAW & PASS: International Journal of Law, Public Administration and Social Studies

Artificial Intelligence and the Right to Equal Education: A Legal Framework for Algorithmic Educational Justice

Sally Awad Elsakka, Nasr Al-Sayed Rashid, Hassan H. Ghofair

The rapid adoption of artificial intelligence (AI) in education is reshaping how learners access knowledge, receive instruction, are assessed, and are classified by educational institutions. Although AI can expand personalization, accessibility, and educational efficiency, its deployment may also generate new forms of inequality through unequal access to advanced technologies, algorithmic bias, opaque profiling, data-intensive surveillance, and differential quality of AI-mediated learning. This article examines whe …

31.08.2026journal-article

al-Qanatir: International Journal of Islamic Studies

REPUTATIONAL RISK MANAGEMENT IN MALAYSIAN ISLAMIC PUBLIC INSTITUTIONS: TOWARDS A MAQĀṢID AL-SHARĪʿAH-BASED TRACKING MODEL

Mohammad Mahyuddin Khalid, Azri Bhari, Mohd Faiz Mohamed Yusof, Mohd Yusra Abdullah, Zulaipa Ruzulan, Zakiah Samori

Malaysian Islamic public institutions, specifically the Department of Islamic Development Malaysia (JAKIM) and State Islamic Religious Councils (SIRCs), play a pivotal role in managing religious affairs and public resources such as zakat and waqf. The effectiveness of these institutions depends on public trust and the capacity to maintain administrative integrity. This article examines the necessity of implementing formal reputational risk management within Islamic public institutions. Drawing on Islamic governance …

31.08.2026journal-article

Journal of Pharmacy Technology

Impact of Nonmedical Adalimumab Switches in a Rheumatology Patient Population

Stefania DelPrete, Krista Dessureault, Molly Bachman, Morgan Merchand, Derek Devine, Amanda G. Kennedy, Julie MacDougall

Background: Adalimumab is an antitumor necrosis factor agent approved by the U.S. Food and Drug Administration in 2002 for the treatment of various rheumatologic diseases. Recent approval of adalimumab biosimilars presents an important area of study to determine real-world efficacy and cost savings of biosimilars. Objectives: The primary objective was to evaluate the impact of nonmedical, insurance-mandated adalimumab switches on disease activity. The secondary objective was to assess the financial impact of these …

31.08.2026journal-article

Frontiers in Public Health

Sex and age are associated with host immune responses and multi-organ dysfunction in hospitalized patients with COVID-19

Guochao Zhang, Yingying Zhao, Xiaoxia Chang, Qi Gao, Yunchao Zhang, Yanjun Lai

Objectives Sex- and age-related disparities are independent risk factors for poor COVID-19 outcomes, but underlying mechanisms remain unclear. Methods This retrospective cohort study included 395 hospitalized COVID-19 patients (December 2022–March 2023). Biomarkers of multi-organ injury and immune responses were analyzed to evaluate the impact of sex and age on disease progression and clinical outcomes. Normality was assessed with the Shapiro–Wilk test; Student’s t or Mann–Whitney U tests were used accordingly, wit …

31.08.2026journal-article

Frontiers in Public Health

Digital compassion fatigue in nurses: an evolutionary concept analysis

Xiaobing Wu, Xia Yang

Electronic health records, telehealth and home monitoring are changing the psychosocial conditions of nursing work, and digital compassion fatigue in nurses has recently been proposed to describe compassion fatigue that may evolve within technology-mediated care. Direct evidence remains minimal, comprising two concept studies and one commentary, and the boundaries with compassion fatigue, burnout, technostress, moral distress and digital fatigue are unsettled. This study applied Rodgers' evolutionary concept analys …

31.08.2026journal-article

Journal of Korean Gerontological Nursing

Factors associated with gerontological nursing practice among nurses in comprehensive nursing care service units: A cross-sectional descriptive study

Hye Bin Park, So Young Shin

Purpose: In comprehensive nursing care service units (CNCSUs), where family caregivers are rarely present, nurses are primarily responsible for both medical treatment and daily care, making professional gerontological nursing practice essential. This study investigated factors associated with gerontological nursing practice among nurses in CNCSUs. Methods: A cross-sectional descriptive study was conducted. The participants included 153 nurses at two general hospitals in Korea. A structured self-reported questionnai …

31.08.2026journal-article

Frontiers in Medicine

Risk stratification of ibrutinib toxicity co-administered with triazole antifungals: insights from real-world pharmacovigilance and clinical evidence

Shiyun Li, Zijuan Li, Shiqiao Wang

Objective The co-administration of ibrutinib and triazole antifungals results in known pharmacokinetic interactions, but the comprehensive clinical risk profile and grading characteristics remain underexplored. This study integrated real-world pharmacovigilance data, clinical pharmacokinetic studies, and published clinical cases to evaluate the comparative safety profiles and risk gradients of these drug combinations. Methods Adverse drug events (ADEs) from the FDA Adverse Event Reporting System (FAERS) between Q1 …

31.08.2026journal-article

Frontiers in Microbiology

Prophage landscapes in clinical MRSA: safety profiling and discovery of Lys81, a broad-spectrum bacteriolytic enzyme

Fangfei Ran, Minglei Yang, Xiuxiu Zeng, Hui Su, Jiayi Dong, Guosheng Gao, Airong Hu, Yaoren Hu, Yuechao Sun

Introduction Methicillin-resistant Staphylococcus aureus (MRSA) poses a significant threat to global healthcare, requiring novel therapeutic strategies. Prophages, latent phage genomes integrated into bacterial chromosomes, are important resources for antimicrobial development due to their genomic stability and genetic engineering potential. Methods In this study, we performed genomewide sequencing on 329 MRSA isolates to predict prophage sequences, followed by analyses of these prophages—including examinations of …

31.08.2026journal-article

Frontiers in Public Health

Effects of the COVID-19 pandemic on working conditions and mental health among employees in health and social services

Claudia Peters, Madeleine Dulon, Jan Felix Kersten, Christofer Hartung, Albert Nienhaus, Anja Schablon

Background The COVID-19 pandemic has posed major challenges in the workplace. This exploratory, cross-sectional study investigated the association between occupational activities and mental health. Methods In 2023, 576 employees from health and social care institutions were surveyed about their occupational situation, their self-assessed ability to work, health-related issues, as well as their mental health and quality of life. Results The respondents were predominantly women with an average age of 49 years. Of the …

31.08.2026journal-article

Journal of Neurosciences in Rural Practice

Proactive integrated mental health care (PIMHC) model for hospitalized surgical patients: Development and feasibility study

Kewithinwangbo Newme, Abhilash Goyal, Jay Kishor Soren, Ashok Puranik, Nibedita Das, Ramdas Ransing

Objectives: Mental health disorders (MHDs) adversely affect the surgical outcomes, including pain, hospital stay, complications, and mortality. Proactive consultation–liaison (C-L) psychiatry models are widely used for surgical patients in high-income countries, but they have yet to be developed and systematically evaluated in Indian healthcare settings. The present study aims to develop and evaluate the feasibility of a proactive integrated mental health care (PIMHC) model for surgical inpatients in a tertiary cen …

31.08.2026journal-article

Alzheimer's & Dementia

Longitudinal functional network connectivity changes across the clinical stages of C9orf72 hexanucleotide repeat expansion carriers

Liwen Zhang, Suvi Häkkinen, Youjin Jung, Maria Luisa Mandelli, Dana Leichter, Chiadi U. Onyike, Julio C. Rojas, Jolina Lombardi, Maria Luisa Gorno‐Tempini, Jennifer S. Yokoyama, Virginia E. Sturm, Joel Kramer, Brad F. Boeve, Adam L. Boxer, Leah K. Forsberg, Hilary W. Heuer, Kejal Kantarci, Eliana Marisa Ramos, Howard J. Rosen, Bruce L. Miller, William W. Seeley, Taru M. Flagan, Suzee E. Lee, the ARTFL/LEFFTDS/ALLFTD Consortia

Abstract INTRODUCTION Intrinsic functional connectivity network abnormalities in C9orf72 hexanucleotide repeat expansion carriers emerge during the asymptomatic phase, yet longitudinal studies remain limited. We examined cross‐sectional abnormalities and longitudinal connectivity changes across clinical stages. METHODS We analyzed task‐free functional magnetic resonance imaging (fMRI) and structural MRI data in 36 asymptomatic (aSxC9), 17 prodromal (proC9), and 29 symptomatic (SxC9) carriers, and 107 healthy contro …

31.08.2026journal-article

Nursing Education Perspectives

Applying Metacognitive Strategies in Community Nursing Education: A BOPPPS Model Approach

Cheng Cheng

This study evaluated the use of a metacognitive-based program integrated with the BOPPS model (Bridge-in, Objective, Preassessment, Participatory Learning, Postassessment, and Summary) in a sample of 78 third-year nursing students. Metacognitive awareness (monitoring, evaluation, and regulation) was assessed using the Metacognitive Awareness Inventory before and after the course; reflective essays captured learning experiences. Paired-sample t tests and thematic analysis revealed significant gains in monitoring and …

31.08.2026journal-article

Hitit Sosyal Bilimler Dergisi

The merit principle in the public personnel regime in Türkiye: recent trends through the decisions of the Council of State

Abdurrahman Muhammet Banazılı, Umut Turgut Yıldırım

This study analyzes the judicial interpretation of merit principle in public administration within the framework of the current Council of State decisions. The main problem of the research concerns the normative criteria the administrative judiciary uses to assess the principle of merit, and its resultant consequences for the interrelation between administration’s discretion and rule of law. A deficiency in Turkish discourse on merit tends to discuss it exclusively within the purview of constitutional norms, legisl …

31.08.2026journal-article

INTERNATIONAL JOURNAL OF INNOVATIVE RESEARCH IN MULTIDISCIPLINARY EDUCATION

Building A Quality Ecosystem for Clinical Psychology: Integrating Competence, Ethics, Supervision, and Professional Regulation

Vu Xuan Huong

An important consideration in clinical psychology is that of professional quality. Having appropriate standards is not enough; they must shape both the training of clinical psychologists and the work that they do. Therefore, all of the elements that contribute to the professional quality of clinical psychologists, that is, competence, ethics, supervision, accreditation and regulation, must function together. This critical integrative review sets out to explore the relationships between these elements. A record-veri …

31.08.2026journal-article

Annals of Rehabilitation Medicine

Digital Health Approaches to Geriatric Rehabilitation: A Narrative Paper

Changwon Moon, Pamela Bregasi, Aminreza Khandan, Bijan Najafi

Rapid population ageing is widening the gap between geriatric rehabilitation needs and constrained care capacity. Digital health offers new ways to deliver rehabilitation beyond traditional settings, but its role and limitations in geriatric practice remain unclear. To provide a narrative synthesis of how digital health can support geriatric rehabilitation, highlighting advances, challenges, and future directions. We conducted a narrative review of digital health approaches in geriatric rehabilitation, informed by …

31.08.2026journal-article

Annals of Rehabilitation Medicine

Immediate Effects of Manual Muscle Stretching on Respiratory Capacity, Heart Rate Variability, and Diaphragmatic Function in Patients With COPD

Hsin-Lun Yang, Jian-Cheng Peng, Yu-Ting Huang, Hui-Ching Cheng, Ching-Hsia Hung, Chiung-Zuei Chen, Sheng-Yuan Wang, Chin-Wei Kuo, Kun-Ling Tsai

Objective: To investigate the acute physiological responses following a single session of manual muscle stretching in patients with moderate to severe chronic obstructive pulmonary disease (COPD).Methods: A single-group pre–post design was used. Nineteen participants with moderate to severe COPD received one session of manual stretching, incorporating passive stretching and muscle energy techniques targeting the anterior scalene, upper trapezius, pectoralis, and diaphragm muscles. Primary outcomes included spiromet …

31.08.2026journal-article

Frontiers in Dementia

Evaluating the correspondence of neuropsychological profiles with clinical diagnostic criteria for frontotemporal lobar degeneration and Alzheimer's disease: insights from k-means clustering

Marie Söntgerath, Simone Cutini, Angelika I. T. Thöne-Otto, Annerose Engel, Frank Regenbrecht, Maryna Polyakova, Karsten Mueller, Nico Scherf, Fabiola Boehm, Sarah Anderl-Straub, Bernhard Landwehrmeyer, Bernhard Danek, Janine Diehl-Schmid, Klaus Fassbender, Klaus Fliessbach, Holger Jahn, Holger Kornhuber, Martin Lauer, Johannes Prudlo, Matthis Synofzik, Jens Wiltfang, Markus Otto, Matthias L. Schroeter

Introduction Diagnosis of frontotemporal lobar degeneration (FTLD) is complicated by high heterogeneity within diagnostic groups and overlap between them. Using an unsupervised machine learning technique this study aimed to increase understanding of neuropsychological profiles in the spectrum of FTLD syndromes and to assess the consistency of these neuropsychological profiles with diagnostic criteria. Methods Data from the German FTLD Consortium (FTLD-c) including behavioral variant of frontotemporal dementia (bvFT …

31.08.2026journal-article

European Journal of Endocrinology

Metyrapone-Associated Improvements in Health-Related Quality of Life in Cushing's Syndrome

Emese Mezôsi, Lynnette K Nieman, Carla Scaroni, Marco Boscaro, Timo Deutschbein, Natacha Driessens, Carmen E Georgescu, Marcin Motyka, Alicja Hubalewska-Dydejczyk, Barbara Jarzab, Dominique Maiter, Martin Reincke, Paola Loli, Benedetta Zampetti, Aysegul Atmaca, Corin Badiu, Albert Beckers, Marek Bolanowski, Francesco Cavagnini, Nicole Unger, Roberta Giordano, Felicia Alexandra Hanzu, Massimo Terzolo, Arnau Domenech, Myriam Bou Nader, Ninet Sinaii, Judit Tőke, Miklós Tóth

Abstract Objective This analysis describes the evolution of HRQoL over 36 weeks of metyrapone treatment in the PROMPT study, identifying patterns of early, delayed improvement, or persistence using item-level resolution. Design and Methods Longitudinal analysis of patient-reported outcomes from PROMPT (NCT02297945), a prospective, open-label, multi-country study of metyrapone in 49 evaluable adults with confirmed endogenous CS. HRQoL was assessed with the CushingQoL (0-100; higher = better QoL) and Tübingen CD-25 ( …

31.08.2026journal-article

International Journal of Medical and Health Research

Enhancing Radiation Safety Practices and Patient Awareness in Rural Healthcare Facilities in Enugu State, South East Nigeria: A Cross-Sectional Public Health Study

Okechukwu Sixtus Oluebube, Odo Oliver Izuchukwu, Okike Abel Somadina, Chikamnele Favour Chimezirim, Olinya Josephine Chinenye, Chisom Franklin Omerike, Ahmad Aliyu Gulani, Shehu Muhammad Awwal, Eze Sunday Chiayalam, Casmir N. Ochie

Medical imaging utilizing ionizing radiation has significantly improved diagnostic accuracy and patient management in modern healthcare. However, inadequate radiation safety practices and poor patient awareness remain critical challenges, particularly in rural healthcare settings in developing countries. This study assessed radiation safety practices among healthcare workers and patient awareness regarding diagnostic radiation exposure in rural healthcare facilities in Enugu State, South East Nigeria. A descriptive …

31.08.2026journal-article

Clinical and Translational Medicine

Cancer cell‐selective ectopic expression of CD20 as an antigen enables rituximab repurposing for solid tumour immunotherapy

Ziyan Kong, Yile Wang, Yunqi Zhao, Lu Wang, Zhimin Fan, Yongqian Shu, Jinke Wang

Abstract Background Despite the clinical success of cancer immunotherapies, their efficacy is often compromised by antigen‐related problems, including downregulation, loss, and off‐tumour toxicity. Methods To overcome these limitations that challenge the current immunotherapies dependent on native antigens, we here describe a new cancer immunotherapy strategy that artificially and specifically expresses a clinically validated antigen on variant tumours and thus repurposes clinical antibody drugs to treat cancers no …