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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
04.08.2026journal-article

Aging Clinical and Experimental Research

Radiofrequency Echographic Multi-Spectrometry for bone health assessment in prostate cancer patients receiving Androgen deprivation therapy: A prospective comparative observational study

Manuela Montatore, Riccardo Guglielmi, Amanda Isaac, Maria Grazia Capasso, Antonio Corvasce, Federica Masino, Giuseppe Guglielmi

Abstract Background Androgen deprivation therapy (ADT), used in selected patients with prostate cancer (PCa), is associated with accelerated bone loss and increased fragility fracture risk. Radiofrequency Echographic Multi-Spectrometry (REMS) is a non-ionizing ultrasound-based technique for axial bone mineral density (BMD) assessment. Aim To evaluate REMS-derived BMD at the lumbar spine and femoral neck in men with PCa receiving ADT and in age- and body mass index-matched healthy controls. Methods In this cross-sec …

04.08.2026journal-article

SocietàMutamentoPolitica

Legal Aid at the Margins: Realizing Rights for People Experiencing Homelessness in Italy

Maria Chiara Pedroni

Legal aid is widely recognised as a key mechanism for enabling access to justice, however its inherent ambivalences and structural limitations have been highlighted in the literature. This paper explores how access to rights is enacted in everyday practice through a qualitative study of a volunteer-based organisation of “street lawyers” operating in Italy, which provides free legal aid to people experiencing homelessness. Drawing on volunteers’ accounts of their everyday practices, role interpretations, and encount …

04.08.2026journal-article

Frontiers in Psychiatry

Social isolation, loneliness, disability progression, and mortality among older adults with cardiac disease: a longitudinal NHATS study

Xiaoyu He, Yuxiao Sun, Chang Zhou, Yue Yu, Shangwei Huang, Tianwen Wei, Jieyun You, Qi Zhang

Background Cardiac disease is the leading cause of morbidity and mortality among older adults, yet the psychosocial pathways through which it accelerates functional decline remain poorly characterized. Social isolation and loneliness are plausible mediators, but their longitudinal roles in the cardiac disease–disability–mortality cascade have not been examined in an integrated framework. Methods We analyzed 5,654 US Medicare beneficiaries aged ≥65 from the National Health and Aging Trends Study (NHATS) followed acr …

04.08.2026journal-article

Genes & Nutrition

Epigenetic changes reveal that vitamin B12 intake is associated with lower insulin resistance in older adults

Chao-Qiang Lai, Laurence D. Parnell, Yu-Chi Lee, Bruce S. Kristal, Oladimeji J. Akinlawon, Margaret P. Winderman, Tamara K. Reed, Liam Fouhy, Kelsey M. Mangano, Josiemer Mattei, Katherine L. Tucker, José M. Ordovás

Abstract Background Dietary choices influence both risk and development of type 2 diabetes (T2D), but the precise mechanisms remain incompletely described. Dietary intake and lifestyle behaviors can alter epigenetic states with subsequent modulations on gene expression which then can change the risk of T2D. Methods An epigenome-wide association study was conducted to identify any epigenetic links to diabetes risk by investigating epigenetic changes during a 6-year follow-up in 374 participants who were free of T2D …

04.08.2026journal-article

Frontiers in Public Health

Caregiving experiences and support challenges of older caregivers from the perspective of the digital divide: a qualitative study

Qi Liu, Lisha Xia, Chun Wu, Weina Dang, Juelian Li, Yali Liu, Chao Shang, Yu Deng, Jinxia Zhang

Purpose This study aims to explore the caregiving experiences and support challenges faced by older caregivers when using digital health technologies. By examining these experiences through the lens of the digital divide, this research seeks to provide empirical evidence to support the development of inclusive and age-friendly digital health services. Methods This study employed a qualitative descriptive design. Using purposive sampling, 16 older caregivers of hospitalized older patients were recruited from the car …

04.08.2026journal-article

Therapeutic Recreation Journal

The Empowering Language Framework: A Model for Recreational Therapy to Foster Autonomy in Older Adults

Shelly Bates, Carmen Bowman

With the increasing number of older adults living in nursing and assisted living homes, Certified Therapeutic Recreation Specialists (CTRSs) proactively address issues that impact well-being, such as decreased autonomy. CTRSs serving older adults in the United States utilize a skill set that is uniquely positioned to promote autonomy through therapeutic relationship development and a person-centered care ideology. This conceptual paper proposes the Empowering Language Framework (ELF), an applied practice model that …

04.08.2026journal-article

Frontiers in Built Environment

Summer indoor thermal-humidity environment and thermal comfort of older adults in renovated nursing homes: a case study in Changsha, China

Fupeng Zhang, Lei Shi, Ying Zhang, Simian Liu, Meizhen Long, Wenqian Jiang

With the increasing demand for urban building stock renewal and elderly care facilities, nursing homes renovated from existing buildings have become increasingly common in hot-summer and cold-winter regions. However, whether their indoor thermal-humidity environments can meet the comfort and health needs of older adults remains insufficiently investigated. This study selected three typical renovated nursing homes in Changsha, China, as case buildings. Field measurements, subjective questionnaire surveys, and therma …

04.08.2026journal-article

Healthcare

Weak-Supervision Expectation–Maximization Framework for Identifying Decisional Vulnerability in Older Emergency Department Patients

Devin Sandlin, Steve Arze, Jacob Lane, Ayan Bhakta, Jennifer A. Walker, Anirudh Rayanki, Jenna R. Williamson, Nathan Hoot, Hao Wang

Background and Objectives: Decision-making capacity is essential for informed consent, yet its assessment in emergency departments (EDs) is often subjective and inconsistently documented. Older adults are particularly vulnerable to impaired capacity during acute illness. We aimed to develop a scalable, electronic health record (EHR)-based approach to support early identification of older ED patients at risk of decisional vulnerability using the Medical Information Mart for Intensive Care (MIMIC)-IV database. Method …

04.08.2026journal-article

BMC Geriatrics

Accelerometry-derived physical activity patterns and clinical correlates in Swiss geriatric inpatients: a cross-sectional study

Caroline Yvonne Tanner, Frank Stoller, Miriam Gaehwiler, Livia Vinzens, Dzuza Papik, Jessica Scherz, Patrick Eggenberger, Martina Betschart

Abstract Background Physical activity among hospitalized geriatric patients is very low, contributing to functional decline and delayed recovery. However, posture-sensitive thigh-worn accelerometry has not yet been used to assess physical activity and its clinical correlates in Swiss acute geriatric inpatients. This multicenter cross-sectional study aimed to (a) quantify physical activity patterns and (b) examine associations with demographic and clinical characteristics. Methods Inpatients from two acute geriatric …

04.08.2026journal-article

Video Journal of Education and Pedagogy

Children’s Play with Digital Technologies: Connecting Digital and Non-digital, People, Place, Embodiment and Affect

Lois Peach, Maria Clara Selina Rivera, Lisa Kervin

Abstract There is much concern surrounding children’s digital technology use. Research has shown that educators feel uncertain about, and would like more examples of, how to integrate quality digital pedagogy into their practice. Drawing upon video data of a simulated surfing experience, this article contends with three core hesitations surrounding children’s digital play: that it is sedentary; that it is isolating; and that it disconnects children from offline worlds. The authors engage with theories of affective …

04.08.2026journal-article

Infectious Microbes and Diseases

Efficacy and Renal Safety of Bictegravir/Emtricitabine/Tenofovir Alafenamide (BIC/FTC/TAF) Among People Living With HIV With Early or Mild Renal Injury: A Real World Retrospective Study in China

Yining Zhao, Qinlan Li, Chengyu Gao, Jialu Li, Liangxi Zhu, Jiang Xiao, Hongxin Zhao

Renal dysfunction is common in people living with HIV because of HIV infection and/or adverse effects of some antiretroviral therapy (ART) regimens. Our study aimed to investigate the efficacy and safety of bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) among people living with HIV (PLWH) with early or mild renal injury after 48 weeks of treatment initiation. We enrolled 266 ART-naïve and 39 ART-experienced PLWH who received care at Beijing Ditan Hospital from January 2022 through December 2023. All …

04.08.2026journal-article

Frontiers in Medicine

Beyond chronological age: a decision tree model integrating nutritional and renal function indicators for risk prediction in pre-frail older adults with hepatolithiasis

Yi Qin, Feiyuan Zeng, Rilian Ou, Yun Huang, Yuan Yu, Zhongying Su

Objectives This study develops a decision tree model to predict risks and identify key factors in pre-frail older adults hepatolithiasis patients and performance of models. Methods The study included 451 pre-frail older adults. Two balanced sample groups totaling 294 cases were obtained via Propensity Score Matching (PSM). Risk prediction models for hepatolithiasis were constructed based on the full sample and the two groups via applying the Classification and Regression Tree algorithm. Models’ performance was eval …

04.08.2026journal-article

F1000Research

Protecting Older Persons in the Criminal Justice System: Procedural and Penal Responses in Emirati and French Laws

Gehad AbdelAziz, Enas Alqodsi

At a juncture where criminal law intersects with the vulnerability of the aging human body, age emerges as a decisive criterion for assessing the fairness of criminal justice systems and their commitment to human dignity. With advancing age, physical and psychological capacities often decline, increasing older persons’ exposure to the harms of criminal procedures and punitive measures. This reality calls for a reassessment of whether general legal rules are sufficient to ensure fair and humane treatment of elderly …

04.08.2026journal-article

International Journal of Computer Information Systems and Industrial Management Applications

Diagnosis of Alzheimer's Disease and Frontotemporal Dementia from Electroencephalography Signals

P. Gopala Krishna, J. Somasekar

Alzheimer’s Disease (AD) and Frontotemporal Dementia (FTD) are progressive neurodegenerative disorders that impair cognition, behaviour, and daily functioning, creating significant challenges for early and accurate diagnosis. Their overlapping clinical symptoms make difficult to distinguish AD, FTD, and Cognitively Normal (CN) individuals during the early stages, delaying appropriate intervention and treatment planning. Existing diagnostic approaches are limited by their reliance on binary classification, lack of d …

04.08.2026journal-article

Therapeutic Recreation Journal

Leisure Engagement, Loneliness, and Boredom in Residential Communities of Older Adults

Megan C. Janke, Katie Frankman, Angela Smith, Čedomir Stanojević, Ivanka Simić Stanojević

Research indicates that the prevalence of loneliness and boredom may be higher for older adults living in residential facilities compared to adults who are community-dwelling. Leisure engagement plays a critical role in addressing these public health concerns, and recreational therapists are well positioned to facilitate interventions aimed at reducing these issues. This pilot study examined the relationship between leisure engagement, loneliness, and boredom among 65 older adults living in two residential communit …

04.08.2026journal-article

JAMA

Alzheimer Disease Biomarkers and Assisted Dying

Stanley Lyndon, Lauren M. Behlke, Juan Carlos Urizar, Kirk R. Daffner

This Viewpoint discusses the expansion of blood-based biomarker testing for Alzheimer disease and outlines patient-physician communication strategies for end-of-life questions and physician-assisted death.

04.08.2026journal-article

Information Technology & People

Creating mental imagery of cultural creative product with AR: a mixed-methods study of the affordances and consumer responses

Bin Li, Zhou Qi

Purpose Cultural and creative products is embracing augmented reality (AR) as a new opportunity to explain traditional culture and revitalize heritage marketing. However, effects and psychological mechanisms of this intersection remain underexplored. This study draws upon affordance perspective and develops a conceptual framework based on mental imagery theory, aiming to elucidate affordances and consumer responses of AR cultural creative products through a mixed-methods design. Design/methodology/approach Firstly, …

04.08.2026journal-article

LATAM Revista Latinoamericana de Ciencias Sociales y Humanidades

Apoyo social y bienestar en personas con discapacidad: revisión de la literatura científica, 2021-2026

Andrés Alexander Calero Yupanqui, Monica Alessandra Calero Yupanqui, Katherine Jazmin Carlos Tiquillahuanca, Keiko Clara Campo Motta

El objetivo de la presente revisión sistemática fue analizar la relación entre el apoyo social y su efecto sobre el bienestar en personas con discapacidad. La revisión siguió el método prisma donde se incluyeron estudios de entre los años 2021 a 2026. La búsqueda se realizó en bases de datos de alto impacto como Scopus y Web of Science donde finalmente de 383 artículos recopilados, después de pasar por cada etapa del método prisma, se analizaron 10 artículos que eran los más relevantes. Los resultados evidenciaron …

04.08.2026journal-article

BMC Geriatrics

Effects of dairy product intake and home-based resistance exercise on the physical function in Japanese community-dwelling older adults: results of a real-world randomized controlled trial

Ryo Miyazaki, Naoki Sakane, Hitoshi Ando, Makoto Ayabe, Hirokazu Taniguchi, Masayuki Yamasaki

Abstract Purpose Although the combination of dairy product intake and resistance training has shown benefits for muscle health in older adults, most intervention studies have been conducted under highly controlled conditions, limiting their applicability to real-world settings. Methods We conducted a 12-week pragmatic, open-label randomized controlled trial involving community-dwelling Japanese older adults. Fifty-four adults aged ≥ 65 years were assigned to either a dairy product intake plus home-based resistance …

04.08.2026journal-article

Journal of the Peripheral Nervous System

Burden and Treatment Preference of Probable Neuropathic Pain in 13 592 people: A Cross‐Sectional and Discrete Choice Experiment in the General Population in Malaysia

Wee‐Kiat Tan, Maznah Dahlui, Azhari Rosman, Hiang Leng Tan, Noraidah Guntalib, Siew Pheng Chan, Shalini Sree Dharan, Pei Chiek Teh, Daniel Yi Jie Wong, Kenny Tan, Solomon Tesfaye, Lee‐Ling Lim

ABSTRACT Background and Aim Neuropathic pain (NeuP) is widely underdiagnosed, and treatment‐related adverse events often drive nonadherence. We investigated the probable NeuP prevalence, symptoms recognition, and treatment preferences among the general population in Malaysia. Methods We utilized a digital ID‐Pain questionnaire across nine tertiary hospitals to screen for probable NeuP. We also designed a discrete choice experiment (DCE) to assess participants' ability to differentiate NeuP from nociceptive symptoms …

04.08.2026journal-article

Journal of the American Heart Association

Association of Accelerometer‐Derived Physical Activity with Incident Cardiovascular Diseases and Mortality in People With Severe Mental Illness

Jing Du, Xingya Lei, Qiang Wang, Hongliang Feng, Zezhi Li, Ruizhi Zhang, Yaping Liu, Jihui Zhang, Yujing Zhou, Yannis Yan Liang

Background Cardiovascular vascular disease (CVD) is a leading cause of increased mortality in people with severe mental illness (SMI). This study aims to examine the dose–response and intensity‐specific associations between physical activity (PA) and CVD risk and mortality in people with SMI. Methods This prospective cohort study was conducted on 6313 participants with SMI with accelerometry data from UK Biobank from February 2013 to November 2021. Moderate‐to‐vigorous PA (MVPA) was categorized into 2 groups (<150 …

04.08.2026journal-article

Journal of the American Geriatrics Society

Cognitive Potentially Inappropriate Medications, Quality of Life, and Healthcare Use in Older Adults With Cognitive Disorders

Haowen Hsu, Collin M. Clark, Steven Feuerstein, Robert G. Wahler, Ranjit Singh, David M. Jacobs

ABSTRACT Background Older adults with cognitive disorders, including dementia and mild cognitive impairment, are particularly vulnerable to adverse effects from centrally acting medications. Cognitive potentially inappropriate medications (CogPIMs), including anticholinergics, antipsychotics, benzodiazepines (BZDs), and non‐benzodiazepine hypnotics (Z‐drugs), may worsen well‐being and increase healthcare utilization in this population. This study evaluates CogPIMs exposure and its association with health‐related qu …

04.08.2026journal-article

Journal of Consumer Behaviour

Feeling Younger, Choosing Complexity: How Subjective Age Influences Older Consumers' Preference for Visual Complexity

Xintao Yu, Qing Gu, Xiaochen Liu, Yuangeng Guo, Ou Li

ABSTRACT As population aging accelerates worldwide, older consumers are emerging as an increasingly important consumer segment. However, age stereotypes suggest that, as people grow older, they become increasingly conservative and prefer simplicity. This study challenges this view by examining whether and how feeling younger shapes older consumers' preferences for visual complexity. Building on self‐concept consistency theory, this research develops a theoretical framework and tests it across four experiments invol …

04.08.2026journal-article

Genes

Integrated Single-Cell and Bulk RNA-Sequencing Analysis Identifies an Aging-Related Gene Signature for Prognosis in Breast Cancer

Pengcheng Chen, Yindan Lin, Jingjia Li, Yiwei Gu, Xueyun Zhang

Background: Cellular senescence exerts a complex influence on BRCA progression and TME remodeling. However, the specific roles of ASIGs in regulating the TME and determining patient outcomes remain unclear. Methods: Using TCGA (training), METABRIC (validation), and single-cell RNA-seq datasets, we systematically characterized ASIGs in BRCA. Prognostic ASIGs were identified to define molecular subtypes and construct a 17-gene LASSO-Cox risk model, which was integrated with clinical factors to develop a prognostic no …