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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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Aktuelle Forschung nach Fachgebiet

24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
03.08.2026journal-article

Pakistan Journal of Positive Psychology

Hearing Loss and Depression in Older Adults: Social Isolation and Loneliness as Mediating Pathways. A Narrative Review with Implications for Pakistan

Bisma Imtiaz

Age-related hearing loss is among the most prevalent chronic conditions of later life, and a large observational literature links it to depressive symptoms in older adults. The mechanism most often proposed is psychosocial: hearing loss degrades conversational participation, which produces social disconnection, which produces depression. This review asks whether that pathway carries the effect and which component of disconnection matters, because the answer determines how the problem should be addressed. It establi …

03.08.2026journal-article

Journal of Clinical Medicine

Clinical Characteristics and Determinants of Healing in Older Adults with Chronic Lower Extremity Ulcers: A Retrospective Cohort Study

Berkay Temel, Hale Nur Ertugay Aral, Esra Adışen, Ahmet Burhan Aksakal

Background/Objectives: Chronic lower extremity ulcers are a major cause of morbidity in older adults. However, real-world data on clinical characteristics, microbiological findings, treatment patterns, and outcomes in older adults remain limited. The objective of this study was to evaluate the clinical characteristics and factors associated with healing in older adult patients with chronic lower extremity ulcers. Methods: This retrospective cohort study included patients aged ≥65 years with chronic lower extremity …

03.08.2026journal-article

Journal of the American Geriatrics Society

Missed Opportunities for Fall Prevention: Primary Care Follow‐Up After Emergency Department Discharge in Older Adults

Thomas K. Hagerman, Maryam Nour, Chandana Cherukupalli, Christine Henry, Denicia Peterson, Fabrice Mowbray, Joseph Miller, David Willens

ABSTRACT Introduction Evaluation by a primary care provider (PCP) after an emergency department (ED) visit for a fall is crucial for preventing future falls. However, little is known about the current practice of fall risk assessments and interventions across community and academic primary care clinics. Methods We performed a retrospective chart review of adults 65 and older discharged home after a fall from 9 EDs in Michigan. All primary care visits within 90 days of the index ED visit were included. Patients were …

03.08.2026journal-article

Healthcare

Mental Health Help-Seeking Intentions and Perceived Barriers Among Filipino American Older Adults: An Exploratory COM-B-Informed Cross-Sectional Study

Andrew Thomas Reyes, Reimund Serafica, Franz Henryk Vergara, Marlon Garzo Saria, Carol Manilay-Robles, Erwin William E. Leyva, Lorraine S. Evangelista

Background/Objectives: Filipino Americans are one of the least likely Asian American subgroups to use formal mental health services, even when mental health needs are present. This study used the Capability–Opportunity–Motivation–Behavior (COM-B) framework to examine mental health symptomatology, perceived social support, help-seeking intentions, and perceived barriers to mental health treatment among Filipino American older adults residing in the United States. Methods: We used a cross-sectional descriptive correl …

03.08.2026journal-article

Stresses

Hormetic Stress Responses in Aging: From Molecular Mechanisms to Clinical Translation

João Miguel Alves Ferreira, Sergii Tukaiev

Aging is characterized by a progressive decline in physiological resilience and increased susceptibility to chronic diseases, including neurodegenerative disorders. Emerging evidence indicates that low-dose stressors (collectively termed hormetic stimuli) activate adaptive cellular responses that enhance stress resistance, promote repair mechanisms, and ultimately extend healthspan. This narrative review synthesizes current knowledge on hormesis in the context of aging, with a focus on key molecular pathways includ …

03.08.2026journal-article

Sexuality & Culture

Hierarchies Within Hierarchies: How Race/Ethnicity and Skin Tone Contribute to Body Image Concerns for Men and Gender Diverse People Who Have Sex with Men

Sarah Bonell, Scott Griffiths

Abstract Body image discourse has historically excluded the experiences of men and gender diverse People of Colour who have sex with men (MPCSM). Across 805 Grindr users, we examined associations between race/ethnicity, skin tone, and body image variables for men and gender diverse people who have sex with men (MPSM). We found that MPCSM reported experiencing greater skin tone surveillance than White participants, but that other body image variables did not differ between races/ethnicities. Further, there was a cur …

03.08.2026journal-article

Healthcare

Exercise Habits in Older Adults: A Scoping Review

Ruotong Peng, Jing Chang, Yishu Zhu, Ronghua Yang, Hui Feng, Yinan Zhao

Exercise habits may support long-term exercise maintenance in older adults, yet the construct has been inconsistently defined and measured. This scoping review examined how exercise habits were conceptualized and operationalized, health-related evidence, and factors reported in relation to exercise initiation and maintenance. PubMed, Embase, Web of Science, EBSCOhost, and the Cochrane Library were searched from inception to July 2025 following PRISMA-ScR guidance, and methodological quality was appraised using the …

03.08.2026journal-article

Frontiers in Public Health

Predictors of childhood vaccination and recent influenza vaccination in older Brazilian adults: an analysis using conventional regression and machine learning approaches

Xianglong Xu, Biying Wang, Kubra Maqsood Memon, Chen Sun, Yang Cheng, Fuquan Long

Background Vaccination is an important public health intervention across the life course but its determinants may differ by life stage. We aimed to identify and compare predictors of childhood vaccination and recent influenza vaccination among older adults using conventional and machine learning approaches. Methods We used data from the second wave (2019–2021) of the Brazilian Longitudinal Study of Aging (ELSI-Brazil), a nationally representative cohort of individuals aged 50+. Analyses included 9,211 participants …

03.08.2026journal-article

International Journal of Clinical Science and Medical Research

The Spectrum and Burden of Otologic Disorders in a Geriatric Nigerian Population: A Cross-Sectional Study

Eustace Oseghale, Immaculata Ogechi Akpalaba, Bodeno Ehis

Background: The global population is aging, leading to an increased prevalence of age-related health conditions, including otologic disorders. Objective: To determine the prevalence, pattern, and associated characteristics of otologic disorders in a geriatric population in Southern Nigeria. Methods: A prospective cross-sectional study was conducted over six months (December 2024-June 2025) at the General Practice Clinic. A total of 423 consecutive patients aged 60 years or more were enrolled. Data were collected wi …

03.08.2026journal-article

Healthcare

Beyond Diagnosis: Characterising Symptom Profiles of Dementia in a Resource-Limited South African Clinical Setting

Mphumzi Andreas Dlamini, Laston Gonah, Sibusiso Cyprian Nomatshila

Background: The demographic and clinical heterogeneity of dementia is well recognised; however, the consistency of core symptom profiles across age and gender in clinical populations remains underexplored. This study aimed to determine the burden and distribution of dementia-related symptoms in selected rural health facilities in South Africa. Methods: A retrospective cross-sectional study was conducted among 260 patients with a diagnosed dementia condition. Data on demographics and key symptoms (memory loss, short …

03.08.2026journal-article

Frontiers in Aging Neuroscience

DNA hydroxymethylation-mediated epigenetic modifications in alcohol use disorder

Sampath Raghul Kannan, Krishna Santhoshkumar, Ramasamy Tamizhselvi

Alcohol use disorder (AUD) is a chronic neuropsychiatric condition that causes an increased risk of dementia and deaths worldwide. Evidence indicates that alcohol misuse can induce changes in genetic factors. Alcohol-induced DNA epigenetic modification alters brain function and contributes to AUD. Among these modifications, DNA methylation is highly implicated in AUD; however, 5-hydroxymethylation of 5-methylcytosine mediated by ten-eleven translocation (TET) enzymes produces 5-hydroxymethylcytosine (5hmC), which h …

03.08.2026journal-article

Barongko: Jurnal Ilmu Kesehatan

Faktor Yang Berhubungan Dengan Healthy Aging Pada Lanjut Usia (Lansia) Di Komunitas

Djusmadi Rasyid, Rezqiqah Aulia Rahmat

Latar Belakang: Peningkatan angka harapan hidup menyebabkan jumlah penduduk lanjut usia (lansia) terus meningkat. Kondisi tersebut diikuti oleh meningkatnya kebutuhan terhadap upaya untuk mencapai healthy aging, yaitu proses mempertahankan kemampuan fungsional yang memungkinkan lansia tetap sehat, mandiri, aktif, dan memiliki kualitas hidup yang baik. Healthy aging dipengaruhi oleh berbagai faktor biologis, psikologis, sosial, ekonomi, gaya hidup, serta akses terhadap pelayanan kesehatan. Identifikasi faktor-faktor …

03.08.2026journal-article

Frontiers in Immunology

Risk of systemic rheumatic diseases in people with irritable bowel syndrome: a global-federated cohort analysis

Shuo-Yan Gau, Yu-Jung Su, Shih-Chi Yang, Chien-Chin Chen, Solomon Chih-Cheng Chen, Hui-Chin Chang, Meng-Che Wu

Background Irritable bowel syndrome (IBS) is a prevalent disorder of gut–brain interaction increasingly linked to immune and inflammatory dysregulation. Whether IBS predisposes to systemic rheumatic diseases remains uncertain. Methods We conducted a retrospective cohort study using the TriNetX Global Collaborative Network, which integrates anonymized electronic health records from more than 150 healthcare organizations and 150 million patients worldwide. Adults (≥18 years) diagnosed with IBS (≥2 visits) between 201 …

03.08.2026journal-article

Frontiers in Oncology

A study on the effect of remimazolam on cellular immune function during the perioperative period in older adults who are having laparoscopic surgery for colorectal cancer

Jiafang Wang, Lan Li, Zhong Qi, Zhijun Chen

Objective To investigate the effect of remimazolam on perioperative cellular immune function in elderly patients undergoing laparoscopic colorectal cancer surgery. Methods Sixty elderly patients were randomly assigned to receive either propofol (Group P, n=30) or remimazolam (Group R, n=30) for anesthesia induction and maintenance. Hemodynamic parameters, Bispectral Index (BIS), emergence time, vasopressor requirement, and adverse reactions were recorded. T lymphocyte subsets (CD3 + , CD4 + , CD8 + ) and NK cells w …

03.08.2026journal-article

Australian Journal of Primary Health

Supporting access to primary care for people experiencing homelessness in Australia: a rapid review of the literature

Juliet Thottunkal, Nilakshi Gunatillaka, Elizabeth Forbes, Caroline Arthur, Elizabeth Sturgiss, Jane Desborough

Homelessness affects >122,000 Australians, and is linked to significantly reduced life expectancy and a heightened risk of preventable acute and chronic health conditions. Optimum management by primary care services enables those experiencing homelessness to avoid exacerbations and unnecessary presentations to hospital emergency departments. The aim of this review was to search the available literature to identify strategies that are effective in supporting people who are experiencing homelessness to engage with …

03.08.2026journal-article

Успехи геронтологии

ЭФФЕКТИВНОСТЬ ГЕРИАТРИЧЕСКОЙ РЕАБИЛИТАЦИИ ПАЦИЕНТОВ С РИСКОМ НЕДОСТАТОЧНОСТИ ПИТАНИЯ

Н.К. Рунихина, В.С. Остапенко, Н.В. Шарашкина, М.С. Арефьева, Т.А. Бондаренко, И.П. Малая, Ю.С. Онучина, С.Н. Лысенков, Е.Е. Попов, А.А. Арефьева, Е.Н. Дудинская, О.Н. Ткачева

Цель работы — оценка эффективности 21-дневных комплексных программ восстановления функциональной активности у пациентов 60 лет и старше с риском мальнутриции (РМ+) и нормальным статусом питания (РМ–). В исследование вошли 482 пациента (доля женщин — 80,9 %), риск недостаточности питания выявлен у 96 (19,9 %). На 1-м визите была выполнена комплексная гериатрическая оценка, составлена индивидуальная программа гериатрической реабилитации. 2-й визит проводили после завершения реабилитационных программ для оценки эффект …

03.08.2026journal-article

Успехи геронтологии

ВИЗУАЛЬНЫЙ ВОЗРАСТ И ПРЕЖДЕВРЕМЕННОЕ СТАРЕНИЕ

Ю.А. Мезенцев, О.А. Осипова, А.А. Степанянц, О.М. Павлиди

Визуальный возраст отражает совокупность внешних признаков старения, формирующихся под влиянием генетических факторов, условий окружающей среды, образа жизни и состояния здоровья человека. Отмечена взаимосвязь визуального возраста с биологическим возрастом и развитием сердечно-сосудистых и метаболических нарушений. Рассмотрены основные морфологические изменения кожи и мягких тканей лица, а также роль эндотелиальной дисфункции и окислительного стресса в ускорении процессов старения. Оценка визуального возраста может …

03.08.2026journal-article

Frontiers in Aging

Guided positional stabilization: a hypothesis on the role of targeted interfaces in enhancing upright stability among frail older adults

Mayur Bhatt, Harikrashna Bhatt

Elderly adults are at a higher risk of falls due to many reasons including issues in balance, coordination and overall sensory responsiveness. Falls ultimately threaten health and result in the fear of falling this causes restricted mobility and further decrease in health. Although there are traditional interventions such as railings, walkers or balance therapy which aim to reduce falls, they often function on compensatory mechanisms with little for postural regulation. We hypothesize that Guided Positional Stabili …

03.08.2026journal-article

The Gerontologist

Smartphone technology, social network maintenance, and social participation among Mandarin-speaking older immigrants in Canada

Prince C Ekoh, Sepali Guruge, Jordana Salma, Zhixi C Zhuang, Bharati Sethi, Christine A Walsh

Abstract Background and Objectives The rapid global expansion of digital technologies has reshaped everyday life across generations, yet the role of smartphones in older immigrants’ social well-being remains insufficiently understood. Drawing on the sociotechnical perspective that ageing and technology are co-constituted; our study examines how Mandarin-speaking older immigrants in Canada use smartphones to overcome social isolation and sustain social participation. Research Design and Methods Data were obtained fr …

03.08.2026journal-article

The Journal of Adult Protection

Therapeutic lying in dementia care: social workers’ decision-making and attitudinal dimensions

Rubén Yusta-Tirado

Purpose This study aims to examine the differential roles of the person-focused and lie-focused dimensions of the Attitudes toward Lying to People with Dementia scale (ALPD) in relation to therapeutic lying among social workers. Design/methodology/approach A cross-sectional online survey was conducted with 253 Spanish social workers working with older adults. Correlations, t-tests, logistic regression and linear regression models were performed. Findings Both ALPD dimensions were strongly correlated but showed diff …

03.08.2026journal-article

Nutrients

Natural Bioactive Compounds Targeting Key Hallmarks of Aging: Functional Food Potential of Spermidine, Fisetin, Berberine, and Urolithin A

Wojciech Rzeski, Weronika Rzeska

Naturally derived bioactive compounds that modulate aging-associated mechanisms have attracted growing research interest, yet few reviews examine how such compounds might act together. This narrative review examines four mechanistically distinct compounds, namely spermidine, fisetin, berberine, and urolithin A, as emerging functional food ingredients with scientifically supported effects on key hallmarks of human aging. Spermidine, a dietary polyamine from wheat germ and fermented foods, induces autophagy through E …

03.08.2026journal-article

Journal of the American Geriatrics Society

Patient and Caregiver Expectations for Patient Portal Communication With Providers: Perspectives From an Academic Geriatric Primary Care Practice

Michael G. Rydberg, Meredith A. Gilliam, Casey J. Kelley, Sophia Lourduraj, Joshua D. Niznik

ABSTRACT Background Electronic patient portals play an increasingly important role in healthcare delivery, facilitating communication between patients and providers. Little is known about how and why older adults and their caregivers use the electronic patient portal and perceive its value. Methods We performed a mixed‐methods survey‐based study of patients and caregivers receiving care in a large academic geriatrics practice to characterize electronic patient portal use in this population. All patients receiving c …

03.08.2026journal-article

Journal of Forensic Sciences

Forensic psychiatric evaluation of legal capacity in older adults: Clinical and cognitive correlates

Mehmet Murat Kırpınar, Zeynep Özge Dağoğlu, Sarp Yoldaş, Merve Rana Altunel Ülkü, İrem Yıldırım, Ömer Faruk Demirel

Abstract Forensic psychiatric evaluation of capacity is commonly requested in clinical practice, particularly in relation to financial decision‐making and power of attorney. However, empirical data describing real‐world assessment processes and associated clinical factors remain limited. This study examined patients referred for forensic psychiatric evaluation of capacity in a specialized outpatient setting and explored the relationship between routinely administered cognitive screening measures and clinical determ …

03.08.2026journal-article

Sensors

A Novel Approach to Characterizing Patterns of Real-World Upper-Extremity Use During Walking and Activities of Daily Living in People with Subacute Stroke

Aishwarya Shenoy, Kit B. Beyer, William McIlroy, Karen Van Ooteghem, Kyle S. Weber, Janice J. Eng, Jennifer Yao, Sean P. Dukelow, Gentson Leung, Michael D. Hill, Robert Teasell, Adria Quigley, Marilyn Mackay-Lyons, Anita Mountain, Nathania Liem, Benjamin R. Ritsma, Mark T. Bayley, Courtney L. Pollock

In accelerometer-based measurement, the inclusion of upper extremity (UE) activity during walking can overestimate real-world functional UE use in people post-stroke. This study introduces a comprehensive, accelerometer-based approach to examining real-world UE use, including the contribution of UE activity during walking, and compares UE use during walking versus ADL-based activities. People with subacute stroke wore bilateral wrist and ankle inertial measurement units (IMU) for one week (24 h/day). Agreement betw …