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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
03.08.2026journal-article

The Journal of Adult Protection

Therapeutic lying in dementia care: social workers’ decision-making and attitudinal dimensions

Rubén Yusta-Tirado

Purpose This study aims to examine the differential roles of the person-focused and lie-focused dimensions of the Attitudes toward Lying to People with Dementia scale (ALPD) in relation to therapeutic lying among social workers. Design/methodology/approach A cross-sectional online survey was conducted with 253 Spanish social workers working with older adults. Correlations, t-tests, logistic regression and linear regression models were performed. Findings Both ALPD dimensions were strongly correlated but showed diff …

03.08.2026journal-article

Nutrients

Natural Bioactive Compounds Targeting Key Hallmarks of Aging: Functional Food Potential of Spermidine, Fisetin, Berberine, and Urolithin A

Wojciech Rzeski, Weronika Rzeska

Naturally derived bioactive compounds that modulate aging-associated mechanisms have attracted growing research interest, yet few reviews examine how such compounds might act together. This narrative review examines four mechanistically distinct compounds, namely spermidine, fisetin, berberine, and urolithin A, as emerging functional food ingredients with scientifically supported effects on key hallmarks of human aging. Spermidine, a dietary polyamine from wheat germ and fermented foods, induces autophagy through E …

03.08.2026journal-article

Journal of the American Geriatrics Society

Patient and Caregiver Expectations for Patient Portal Communication With Providers: Perspectives From an Academic Geriatric Primary Care Practice

Michael G. Rydberg, Meredith A. Gilliam, Casey J. Kelley, Sophia Lourduraj, Joshua D. Niznik

ABSTRACT Background Electronic patient portals play an increasingly important role in healthcare delivery, facilitating communication between patients and providers. Little is known about how and why older adults and their caregivers use the electronic patient portal and perceive its value. Methods We performed a mixed‐methods survey‐based study of patients and caregivers receiving care in a large academic geriatrics practice to characterize electronic patient portal use in this population. All patients receiving c …

03.08.2026journal-article

Journal of Forensic Sciences

Forensic psychiatric evaluation of legal capacity in older adults: Clinical and cognitive correlates

Mehmet Murat Kırpınar, Zeynep Özge Dağoğlu, Sarp Yoldaş, Merve Rana Altunel Ülkü, İrem Yıldırım, Ömer Faruk Demirel

Abstract Forensic psychiatric evaluation of capacity is commonly requested in clinical practice, particularly in relation to financial decision‐making and power of attorney. However, empirical data describing real‐world assessment processes and associated clinical factors remain limited. This study examined patients referred for forensic psychiatric evaluation of capacity in a specialized outpatient setting and explored the relationship between routinely administered cognitive screening measures and clinical determ …

03.08.2026journal-article

Sensors

A Novel Approach to Characterizing Patterns of Real-World Upper-Extremity Use During Walking and Activities of Daily Living in People with Subacute Stroke

Aishwarya Shenoy, Kit B. Beyer, William McIlroy, Karen Van Ooteghem, Kyle S. Weber, Janice J. Eng, Jennifer Yao, Sean P. Dukelow, Gentson Leung, Michael D. Hill, Robert Teasell, Adria Quigley, Marilyn Mackay-Lyons, Anita Mountain, Nathania Liem, Benjamin R. Ritsma, Mark T. Bayley, Courtney L. Pollock

In accelerometer-based measurement, the inclusion of upper extremity (UE) activity during walking can overestimate real-world functional UE use in people post-stroke. This study introduces a comprehensive, accelerometer-based approach to examining real-world UE use, including the contribution of UE activity during walking, and compares UE use during walking versus ADL-based activities. People with subacute stroke wore bilateral wrist and ankle inertial measurement units (IMU) for one week (24 h/day). Agreement betw …

03.08.2026journal-article

PLOS One

Prevalence and related factors of high myopia among adults aged 50 years and older in Fujian Eye Study

Yang Li, Qinrui Hu, Bin Wang, Xiangdong Luo, Mingqin Zhang, Xiaoxin Li

Purpose This study aimed to assess the prevalence of high myopia and its associated demographic and ocular factors among residents aged 50 and older in Fujian Province, Southeast China. Methods A population-based cross-sectional eye study was conducted from May 2018 to October 2019, enrolling residents aged 50 and older. Participants completed a questionnaire covering education, income, medical history, and lifestyle habits (including smoking, drinking, and tea consumption). They also underwent physical and ophthal …

03.08.2026journal-article

Frontiers in Aging Neuroscience

Stereological sampling-based estimates of dopaminergic and cholinergic neuron numbers in young adult and aged male and female Fischer 344 × Brown Norway F1 hybrid rats

Hannah E. Phelps, Merritt R. Reese, Swetha Jeyagopal, Aryan Sahota, Wonn S. Pyon, Jennifer L. Bizon, Barry Setlow, Matthew R. Burns

Age is the primary risk factor for neurodegenerative disorders such as Parkinson’s disease and Alzheimer’s disease, which are characterized by profound loss of midbrain dopaminergic neurons and basal forebrain cholinergic neurons, respectively. In addition, loss of these neurons can occur even in “normal” (i.e., non-pathological) aging, and as a result there is growing recognition of the value of aged animals in studying both normal aging and age-related neurodegenerative disease. The Fischer 344 x Brown Norway F1 …

03.08.2026journal-article

Diabetes Technology & Therapeutics

Automated Insulin Delivery System Initiation Safely Improves Glycemic Outcomes in Older Adults with Type 1 Diabetes

Carmen Quirós, Montserrat Granados, María J. Picón, Lía Nattero-Chávez, Eva Aguilera-Hurtado, María del Rosario Vallejo-Mora, Pilar Beato-Víbora, Sharona Azriel-Mira, Jesús Moreno-Fernández, Olga Simó-Servat, Roxana Zavala-Arauco, Gonzalo Díaz-Soto, Nuria Alonso-Carril, María A. Martínez-Brocca, Olaia Diaz-Trastoy, Laura Guerrero, Paula Andújar, María Duran-Martínez, Rosa Márquez, María Piedra-León, Elisenda Climent, Ana Chico

Objective: To evaluate real-world glycemic outcomes, safety, treatment satisfaction, cognition, and frailty in older adults with type 1 diabetes (T1D) using advanced hybrid closed-loop (aHCL), and to compare them with those of matched older adults treated with multiple daily injections (MDIs). Research Design and Methods: Multicenter observational study including 100 adults with T1D from 19 Spanish hospitals who initiated aHCL at ≥65 years and 100 age- and sex-matched MDI users. Glycemic outcomes before aHCL initia …

1 Zitationen
03.08.2026journal-article

JNCI: Journal of the National Cancer Institute

Epigenetic aging during adjuvant chemotherapy for colon cancer and modification by a resistance training intervention

Alexandra M Binder, Erin Weltzien, Elizabeth M Cespedes Feliciano, Justin C Brown, Catherine Lee, Michelle Ross, Kristin L Campbell, Adrienne Castillo, Amalia Pena Perez, Jeffrey A Meyerhardt, Kathryn H Schmitz, Bette J Caan

Abstract Background Cancer survivors experience excess morbidity and functional decline compared with age-matched individuals without cancer, potentially reflecting acceleration of biological aging during cancer treatment. Epigenetic clocks derived from DNA methylation (DNAm) quantify biological aging, but whether changes in these measures during chemotherapy are modifiable remains unclear. Methods We evaluated longitudinal changes in epigenetic age acceleration among adults with stage II-III colon cancer undergoin …

03.08.2026journal-article

Smart and Sustainable Built Environment

Barriers and opportunities in age-friendly retrofitting of older residential buildings: a systematic literature review

Chen Qian, Don Amila Sajeevan Samarasinghe, Claire Flemmer, Vishal Kumar, Kelvin Zuo

Purpose The purpose of this study is to identify the key barriers and opportunities shaping the age-friendly retrofitting of older residential buildings. Design/methodology/approach A systematic literature review was conducted in accordance with Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines using Scopus and China National Knowledge Infrastructure databases. This review is primarily grounded in literature on urban older residential buildings in China, supplemented by relevant studies …

03.08.2026journal-article

Medical Gas Research

Oxidative stress, aging, metabolism, SIRT1, and the gut microbiota: the neurocardiac basis of cognitive loss

Kenneth Maiese

Cardiovascular disease and cognitive loss have a neurocardiac basis. Poor vascular perfusion can impair cognitive function in both Alzheimer’s disease and multiple sclerosis. However, a treatment gap exists because current approaches do not adequately address the shared underlying cellular mechanisms responsible for cognitive dysfunction in these conditions. Current treatments for cognitive impairment in diseases such as cardiovascular disease, Alzheimer’s disease, multiple sclerosis, and diabetes often fail to ful …

03.08.2026journal-article

Metals

Pre-Aging Prior to Delayed Artificial Aging Modulates Precipitation Behavior and Strengthening Response in an Al-Mg-Si-Cu Alloy

Qingyong Zheng, Huixue Jiang, Yuxing Tian, Guanmei Niu, Mingchao Yu, Xiaobin Guo, Zhihao Zhao, Gaowu Qin, Hutian Li

Room-temperature storage after solution treatment and quenching is often unavoidable during the industrial processing of Al-Mg-Si-Cu alloys, but its interaction with pre-aging and the subsequent artificial aging response remains insufficiently quantified. Here, we demonstrate a pre-aging-assisted delayed artificial aging strategy to regulate β″/L precipitation and improve the strengthening response of an Al-Mg-Si-Cu alloy after short-term room-temperature storage. After solution treatment and quenching, the alloy w …

03.08.2026journal-article

Frontiers in Aging

Promoting physical activity and physical functioning among residents in nursing homes – lessons learnt by the PROGRESS project

Vera Belkin, Berit K. Labott, Claudia Voelcker-Rehage

Introduction Nursing home residents show high sedentary behavior and limited physical functioning, while structural constraints hinder sustainable prevention. This study examined how group-based physical exercise and environmental interventions, such as activity-promoting materials and interior design, can be integrated into everyday care to promote a physical activity–promoting culture in nursing homes and identified key organizational and individual determinants of sustainable implementation. Methods PROGRESS was …

03.08.2026journal-article

The Gerontologist

Aging Alone: Lifestyle and Unmet Needs Among Unpartnered Middle-Aged Adults Preparing for Later Life in Urban Taiwan

Shen-Min Wang, Ching-Ju Chiu, Szu-Yu Hou

Abstract Background and Objectives Population aging, delayed marriage, one-person households, and weakening assumptions of spouse-based care make unpartnered aging an emerging concern in Taiwan. This study examined how unpartnered middle-aged adults in urban Taiwan prepare for later life and developed two grounded models of solitary aging. Research Design and Methods A convergent, qualitatively weighted mixed-methods design was used. Eleven unpartnered adults aged 43–56 completed interviews and questionnaires asses …

03.08.2026journal-article

Current Alzheimer Research

The Black Hole of the Brain: A Novel Energy-Based Therapeutic Perspective for Alzheimer’s Disease

Shima Motamedi, Isaac Karimi

Abstract: Alzheimer’s Disease (AD) is considered a devastating and often underrecognized global health burden. Despite extensive ongoing research, effective treatments remain limited by an incomplete understanding of its multifarious pathogenesis, more than a century since the first report of AD in 1906. This review proposes a novel conceptual framework that draws parallels between entropy- driven systemic collapse in physical systems and neurodegeneration in AD. Specifically, it highlights how entropy may lead to …

03.08.2026journal-article

Frontiers in Public Health

Risk factors for skin tears in the older adults: a systematic review and meta-analysis

Aixuan Guan, Yuxin Huang, Yating Guo, Huimin Huang, Jing Lv, Chaoqun Yang, Shi Wei, Bihong Chen

Background A skin tear is a traumatic wound caused by mechanical forces, including removal of adhesives and patient handling, the depth of which may vary (not extending through the subcutaneous layer). With the global trend of an aging population, it has become a problem that requires great attention in clinical care. Previous studies have investigated the risk factors for ST in older adults (e.g., age, history of ST, malnutrition, etc.). However, the results of the studies varied widely, and the correlation coeffi …

1 Zitationen
03.08.2026journal-article

Frontiers in Aging Neuroscience

Joint trajectories of obesity and depressive symptoms and risk of incident glaucoma: a 16-year prospective cohort study from the Health and Retirement Study

XiaoDan Xu, Yuting Hu, Fuju Shi, Jingtao Wu, Yongfeng Wu, Yanfeng Zhu, Jing Yang

Background Obesity and depression frequently co-occur in older adults and share pathways potentially relevant to glaucoma, yet their dynamic co-evolution and joint contribution to glaucoma risk remain poorly characterized. Objectives This study aimed to identify joint longitudinal trajectories of body mass index (BMI) and depressive symptoms and evaluate their association with incident glaucoma. Methods Among 6,154 participants from the Health and Retirement Study (2000–2016) in the United States, we applied group- …

03.08.2026journal-article

JKG (JURNAL KEPERAWATAN GLOBAL)

Toward an Empowerment-Based Nursing Framework for Managing Multimorbidity in Older Adults<b></b>

Argi Virgona Bangun, Minerva B. De Ala, Marietta Fabros, Marcus Ochoa

Background: Population aging presents major challenges for healthcare systems, particularly in managing the complex needs of older adults with multiple chronic conditions (multimorbidity). This study explores behavioral, cognitive, and contextual factors influencing how older adults navigate complex treatment regimens, with the goal of developing an empowerment-based nursing framework. Methods: This sequential explanatory mixed-methods study involved 127 older adults with chronic conditions in the quantitative phas …

03.08.2026journal-article

Journal of Adolescent Research

“Teenagers are a reflection of your parenting – everyone is judging”: Perceived Pressures and Coping Among Parents of Older Adolescents at the Transition

Katherine M. Ryan, Melanie J. Zimmer-Gembeck, Tanya Hawes, Elia Edwards, Riley Scott

Parents face unique challenges as their children leave secondary school and advance into the emerging adulthood years. This study explores parents’, primarily mothers’, experiences of parenting as their children (16 – 19 years) were in their last months of school. Thirty Australian parents (28 mothers and 2 fathers) were individually interviewed. Reflexive thematic analyses revealed two overarching themes with seven subthemes. Overarching themes were the pressures of parenting an older adolescent and parents’ ways …

03.08.2026journal-article

Frontiers in Public Health

Loneliness among community-dwelling older adults across biological, clinical and psychosocial domains before and during the COVID-19 pandemic: a systematic review

Georgia Casanova, Giorgia Fattorini, Sara Santini, Marta Balietti, Ilaria Barboni, Robertina Giacconi, Giovanni Lamura

Background Loneliness is a subjective and distressing experience resulting from a discrepancy between desired and actual social relationships and represents an important public health concern among community-dwelling older adults. Although it can occur throughout the life course, older adults are particularly vulnerable because of age-related conditions such as multimorbidity, mobility limitations, sensory impairments, widowhood, and retirement. These factors highlight the need to understand loneliness as a multifa …

03.08.2026journal-article

Head & Neck

Current Evidence on Best Practice Dental Survivorship Care for People With Head and Neck Cancer: An Overview of Systematic Reviews and Emerging Evidence

David G. Tighe, Rebecca Venchiarutti, Isidoro Ruisi, Purnima Sundaresan

ABSTRACT Introduction Head and neck cancer (HNC) survival is improving, increasing the need to address long‐term survivorship issues. Dental survivorship—care before, during, and after treatment—remains inconsistent across services. We conducted a review of systematic reviews and emerging evidence to inform contemporary dental survivorship care for HNC patients. Methods This review followed PRISMA guidelines. Eligible studies included adults with HNC receiving oral and dental interventions before, during, or after …

03.08.2026journal-article

Journal of Eating Disorders

Ethical issues related to restrictive practices for anorexia nervosa in young people

Angela Yan, Michele Yeo, Emily Wilson, Jenny O’Neill, Lynn Gillam

Abstract Background Anorexia nervosa (AN) is an eating disorder affecting many young people. In severe AN, complications associated with profound weight loss and malnutrition can arise, and restrictive measures (e.g., manual force, devices, or medications) may be employed to ensure treatment of patients at imminent risk of harm. This narrative review explores the ethical issues in restrictive practices or coercive treatment for young people with AN. Methods 345 papers were initially retrieved from online databases …

03.08.2026journal-article

Microorganisms

Aging-Induced Physicochemical Changes in Petroleum- and Biobased Microplastics Influence Depolymerization and Gut Microbiota in Tenebrio molitor Larvae

Yuan Tian, Meng-Qi Ding, Jie Ding, Xin-Ran Ren, Sheng-Qiang Fan, Bing-Feng Liu, De-Feng Xing, Lei Zhao, Zhi-Rong Zhang, Lu-Yan Zhang, Nan-Qi Ren, Shan-Shan Yang

In this study, we evaluated the influence of physicochemical aging on the biological processing and depolymerization performance of polyethylene (PE) and polylactic acid (PLA) by Tenebrio molitor larvae, with the goal of improving insect-based plastic treatment strategies. PE and PLA subjected to a sequential freezing–ultraviolet aging protocol showed modest increases in total larval consumption (approximately 11% for PE and 10% for PLA) compared with pristine materials. Aging also accelerated the processes related …

03.08.2026journal-article

Rainbow: Journal of Literature, Linguistics and Culture Studies

The Persistence of Social Power in Post-Catholic Ireland: A New Historicist Study of Sally Rooney's Normal People

Husein Asadus Shahra, Karina Hanum Luthfia

This study aims to examine how social power persists in post-Catholic Ireland as represented in Sally Rooney's Normal People (2018). Set against the backdrop of Ireland’s transition from a society strongly influenced by Catholic authority to a more liberal and secular social order, the novel reveals that the decline of religious influence does not necessarily eliminate mechanisms of social control. Using a qualitative descriptive method and Stephen Greenblatt’s New Historicist approach, this study analyzes how expe …