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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
26.08.2026journal-article

The Journal of Aging and Social Change

Promoting and Implementing Active Aging in Italy

Franca Maino, Antonio Talarico, Manuela Cristaldi, William Revello

Aging is a significant challenge: The number of people aged 80 and over is expected to rise from 142 million in 2020 to 426 million by 2050, per the World Health Organization. In Italy, where older adults represent a substantial share of the population, innovative models are needed to promote active, healthy, and inclusive aging beyond traditional care-based approaches. This article presents an exploratory qualitative case study named Abitare Villa Mater, focusing on the design and implementation process of a pilot …

26.08.2026journal-article

Frontiers in Aging Neuroscience

Two serial MoCA assessments may support biomarker-sparing triage between Parkinson’s disease/Lewy body dementia and frontotemporal dementia: a progressive inclusion analysis of 1,129 participants

Wei Lin, Sanjeet S. Grewal, Richard W. Byrne

Reliable differentiation of Parkinson’s disease/Lewy body dementia (PD/LBD) from frontotemporal dementia (FTD) affects treatment strategy and clinical trial eligibility, yet confirmatory biomarker testing remains costly and unevenly available. Whether routine cognitive trajectories can support testing prioritization has not been systematically quantified. We performed a progressive inclusion analysis of 1,129 National Alzheimer’s Coordinating Center participants with PD/LBD ( n = 385) or FTD ( n = 744) to determine …

26.08.2026journal-article

Frontiers in Nutrition

Day-7 caloric intake as an early dynamic prognostic marker for subsequent mortality in older patients with dysphagia: a landmark cohort analysis

Jianxian Zhang, Xiaojing Yun, Yan Xue

Background Early nutritional status may influence prognosis in older adults with dysphagia receiving artificial nutrition. However, the predictive value of caloric intake shortly after initiation of enteral or parenteral nutrition remains unclear. This study aimed to investigate the association between day-7 caloric intake and subsequent all-cause mortality in older Japanese patients with dysphagia and assess its potential as an early dynamic prognostic marker. Methods We conducted a day-7 landmark cohort analysis …

25.08.2026journal-article

International Journal of Molecular Sciences

Effects of 12-Week Resistance Training on Metabolic and Immune Responses in Normal-Weight and Older Women with Obesity

Nicolás Vidal-Seguel, Alexis Sepúlveda-Lara, Juan Carranza-Leiva, Carlos Márquez, Nolberto Huard, Jorge Sapunar, Luis A. Salazar, Sergio Sanhueza, Solange Torres, Estefanía Nova-Lamperti, Gabriel Nasri Marzuca-Nassr

Ageing and obesity represent major public health challenges and are associated with metabolic dysfunction, chronic inflammation, and loss of skeletal muscle mass. Resistance training (RT) is an effective strategy to increase muscle mass; however, its effects on metabolic and immune parameters in older women with obesity remain unclear. The study aimed to compare the effects of 12-week progressive overload RT programme on metabolic and immune responses in women aged 60–79 years with obesity and normal-weight women. …

25.08.2026journal-article

Transportation Research Record: Journal of the Transportation Research Board

Practical Long-Term Oven-Aging Protocols for Balanced Mix Design: From Mixture Design to Production

Ilker Boz, Elie Y. Hajj, Jhony Habbouche, Stacey Diefenderfer

The implementation of balanced mix design (BMD) frameworks by state highway agencies has increased the emphasis on performance-indicative tests for asphalt mixture design and production. However, although short-term oven aging (STOA) is routinely applied to simulate production and early-life conditions, long-term oven aging (LTOA) methods remain underutilized owing to their logistical complexity. To address this gap, the Virginia Department of Transportation (VDOT) evaluated streamlined LTOA protocols for dense-gra …

25.08.2026journal-article

Frontiers in Psychology

Psychometric properties of the Kogan Attitudes toward Older People Scale: evidence from a German general-population survey

Birgit Teichmann, Fany Pegiou, Shengze Zhi, Burcu Akpinar Söylemez

Introduction The Kogan Attitudes toward Older People Scale (KAOP) has been translated and validated in numerous languages, although a German version does not yet exist. The present study aimed to translate, adapt, and psychometrically evaluate the KAOP for German-speaking populations. Methods A convenience sample of 419 participants completed the 34-item German KAOP Scale (KAOP-D-34), 211 of whom took part in the retest after four weeks. Reliability was assessed using internal consistency, item analysis, and test–r …

25.08.2026journal-article

Frontiers in Neuroscience

Mapping and modulating brain dynamics in aging and neurodegeneration with electroencephalography and integrated neurotechnologies in primates

Ankur Gupta, Yulia Dembitskaya, Anton Pushkarev, Alexander Popov

Non-human primates (NHPs) provide an essential translational platform for investigating neural mechanisms underlying brain aging and neurodegenerative diseases. Their neuroanatomical organization, cortical complexity, and cognitive capacities share close parallels with those of humans, enabling a degree of experimental precision that rodent models cannot achieve. Electroencephalography (EEG) offers a non-invasive method for monitoring neuronal population activity with high temporal resolution, capturing oscillatory …

25.08.2026journal-article

Journal of Nephrology

Associations of sedentary behavior and physical activity with serum uric acid in middle-aged and older adults with and without chronic kidney disease

Jihoon Kim, Keisei Kosaki, Shoya Mori, Masahiro Matsui, Masaki Yoshioka, Koichiro Oka, Seiji Maeda, Yoshio Nakata, Makoto Kuro-o, Kunihiro Yamagata

Abstract Background Elevated serum uric acid (UA) level is a major health risk, and its accumulation is exacerbated by impaired renal function. Physical activity is a modifiable determinant of serum UA levels. This study used an isotemporal substitution model to examine the associations of reallocating time between activity behaviors with serum UA levels in middle-aged and older adults with and without chronic kidney disease (CKD). Methods A total of 294 middle-aged and older adults with and without CKD (45–85 year …

25.08.2026journal-article

Transdigital

Nivel de autoestima en adultos mayores del municipio de Querétaro, México, mediante la Escala de Autoestima de Rosenberg

Sandra Jenny Cortés Heredia, Victorina Castrejón Reyes, Blanca Judith Lavoignet Acosta, Guadalupe Santes Saavedra

La autoestima, como factor clave en el bienestar, determina cómo las personas enfrentan su vida, influyendo en sus relaciones, confianza y emociones, siendo esencial para promover un envejecimiento activo y saludable. El objetivo del estudio fue comparar los niveles de autoestima entre hombres y mujeres adultos mayores, identificando posibles diferencias significativas entre ambos grupos. Para ello, se utilizó un diseño transversal y descriptivo, con una muestra no probabilística de 53 participantes (24 mujeres y 2 …

25.08.2026journal-article

Journal of Librarianship and Information Science

Serious leisure, information practices, and social support in active aging: Evidence from Taiwan’s senior fitness clubs

Yu-Jung Cheng, Chia-Tung Ho

This study applies Stebbins’s Serious Leisure Perspective to examine how information seeking and social support mediate the relationship between sustained leisure engagement and active aging. Drawing on data from Taiwan’s Senior Fitness Clubs, a mixed-method design was employed, combining a survey of 311 older adults with 15 semi-structured interviews. Structural Equation Modeling tested the relationships among six serious leisure traits and three dimensions of active aging, namely health promotion, social particip …

25.08.2026journal-article

People and Nature

The influence of acoustic characteristics and anthropogenic noise on restorative perceptions of natural soundscapes

Konrad Uebel, Melissa Marselle, Claire Buchan, Simon J. Butler, Nicholas Hanley, Anthony Higney, Eleanor Ratcliffe

Abstract Natural soundscapes are an important cultural ecosystem service that can promote mental health and well‐being. However, the role of specific acoustic characteristics in delivering these benefits and the constraining effects of anthropogenic noise are currently unclear. To address these gaps, we conducted two complementary studies, a representative UK online study ( N = 1529) and a lab‐based study ( N = 62), in which participants listened to nine soundscape samples that differed in both acoustic characteris …

25.08.2026journal-article

Frontiers in Nutrition

Comparative effectiveness of protein or protein-related supplementation combined with resistance or functional exercise for sarcopenia in older adults: a systematic review and network meta-analysis

Boran Yang, Xueyi Chen, Gaiping Yuan, Xinxin Zhang, Dongsheng Lu

Background Resistance and functional exercise are core non-pharmacological strategies for sarcopenia management. Protein or protein-related supplementation is commonly used to support exercise-induced adaptations, but the comparative effects of different supplementation strategies when added to exercise remain unclear. Objective This systematic review and network meta-analysis compared the additional effects of different protein or protein-related supplementation strategies combined with resistance or functional ex …

25.08.2026journal-article

PLOS Mental Health

Changes in quality of life among people with psychosis and their caregivers participating in a community-based rehabilitation intervention in Malawi: A mixed-methods analysis

Mia Buono, Abigail M. Morrison, Hillary Mortensen, Katherine Waddell, Thuy Dao, Bonginkosi Chiliza, Melissa A. Stockton, Bradley N. Gaynes, Kazione Kulisewa, Brian W. Pence

Psychotic disorders are a leading cause of disability in Malawi. Community-based rehabilitation (CBR) interventions may improve quality of life (QOL) for people with lived experience of psychosis (PWLE) and their caregivers by addressing functional challenges and promoting empowerment and social reintegration. However, understanding how QOL may evolve over the course of participation in CBR in low-resource settings remains unknown. This analysis examined changes in QOL among PWLE and their caregivers participating …

25.08.2026journal-article

Periodontology 2000

Dental implant survival, success, and failure in older populations: Beyond chronological age to systemic and local risk profiles

Liza Harutyunyan, Yvonne L. Hernandez‐Kapila

Abstract Aim Assess the effect of chronological aging on dental implant outcomes by reviewing clinical evidence on implant survival, success, failure, and marginal bone loss in elderly populations. Methods An electronic literature search of PubMed/MEDLINE and the Cochrane Library identified human studies published from January 1990 to July 2025 evaluating implant outcomes in elderly patients or age‐stratified cohorts. Randomized controlled trials, systematic reviews, meta‐analyses, cohort, case–control, and cross‐s …

25.08.2026journal-article

British Journal of Occupational Therapy

Bariatric equipment and housing adaptations for people with severe obesity in the community: A detailed micro-costing study

Kath Williamson, Eleanor Grieve, Michael E. J. Lean, David N. Blane

Background: Few data exist on bariatric equipment and housing adaptations prescribed by occupational therapists and used by community-dwelling people with severe obesity (PwSO; body mass index (BMI) ⩾ 40 kg/m 2 ). This study aimed to document the use and costs of equipment and home adaptations by community-dwelling PwSO. Methods: An observational, cross-sectional study was conducted with 25 consenting PwSO. During home visits an investigator-administered questionnaire captured use of community equipment and housing …

25.08.2026journal-article

Autism

English-Language Autism Terminology Preferences of Autistic People and their Parents in the United States: Clustering Illuminates Diverse Views

Patrick Dwyer, Zachary J. Williams, Jennifer E. Magnuson, Tiffany G. Woynaroski

Autism terminology preferences are the subject of considerable debate and various studies, the results of which sometimes conflict. This study examined diversity in terminology preferences in a U.S. sample of 3,181 non-autistic parents and 2,098 autistic people (including 451 autistic parents). The study also examined a particularly wide range of language issues: participants rated terms for autism, possible subgroups within autism, autistic people, autism likelihood, and autistic characteristics. Non-autistic pare …

25.08.2026journal-article

Substance Use & Addiction Journal

Health Harms Associated With Forced Displacements Among People Who Use Drugs in San Francisco, California

Esther O. Chung, Cariné E. Megerian, Leslie W. Suen, Lynn D. Wenger, Bradley Ray, Barrot H. Lambdin, Alex H. Kral

Background: Forced displacements may increase overdose risk among people who use drugs (PWUD) through disruptions to naloxone, safer drug use supplies, and substance use disorder (SUD) treatment access. We investigated whether forced displacements were associated with nonfatal overdose, naloxone access, and SUD treatment access among PWUD in San Francisco, California. Methods: We conducted a cross-sectional survey of 790 PWUD from September 2024 to September 2025. Participants reported number of forced displacement …

25.08.2026journal-article

Journal of Neurophysiology

Age-Related Hearing Loss Begins with Gain, Not Silence: Physiological Compensation in Dorsal Cochlear Nucleus Fusiform Cells During Auditory Aging

Reginald J. Edwards, Michael R. Kasten, Kendall A. Hutson, Malcolm P. Lutz, Paul B. Manis

Age-related hearing loss (ARHL) is the most common cause of sensorineural hearing loss. The cochlear nucleus, the first central auditory structure to receive input from the cochlea, has been shown to be disrupted by ARHL. Fusiform cells (FC), the principal output cell of the dorsal cochlear nucleus (DCN), mature physiologically during hearing onset. Specifically, FCs increase in rate of action potential (AP) rise and decay, stabilizing by postnatal day 14 (P14) in mice. However, whether FC intrinsic electrophysiolo …

25.08.2026journal-article

Healthcare

From Sensory Deprivation to Psychosis: Environmental Mechanisms of Delirium in Dementia—An Eight-Year Retrospective Longitudinal Case Report and Narrative Review

Paulina Teodorczyk, Anna Różańska-Walędziak

Background/Objectives: Delirium in patients with dementia is a multifactorial condition traditionally attributed to acute medical triggers. However, emerging evidence suggests that non-biological factors, including sensory deprivation and environmental instability, may contribute to delirium vulnerability, particularly in vulnerable populations. To explore the temporal associations between non-biological and environmental factors, particularly sensory deprivation and recurrent delirium in a patient with advanced Al …

25.08.2026journal-article

Nursing Reports

Psychometric Evaluation of the Mutuality Scale in Older Adults with Multiple Chronic Conditions and Their Caregivers Living in a Low–Middle-Income Country

Dasilva Taci, Rocco Mazzotta, Manuela Saurini, Sajmira Aderaj, Alta Arapi, Alessandro Stievano, Ercole Vellone, Gennaro Rocco, Maddalena De Maria

Background/Objectives: Multiple chronic conditions (MCCs) are highly prevalent among older adults and require effective collaboration between the patient and caregiver. Mutuality, reflecting the quality of the dyadic relationship, is associated with better self-care and health outcomes. However, the Mutuality Scale (MS) has not been validated on patient–caregiver dyads managing MCCs living in a low–middle-income country (LMIC). Aim: This study seeks to evaluate the structural and convergent validity and reliability …

25.08.2026journal-article

JAMA

End-of-Life and Hospice Care for People Who Are Incarcerated

Nicole Mushero, Alia Moore, Brie Williams

This JAMA Insights discusses the need to expand prison hospice and compassionate release and enrich clinician understanding of the needs of dying patients who are incarcerated to provide compassionate and appropriate end-of-life care.

25.08.2026journal-article

JNCI: Journal of the National Cancer Institute

Epigenetic aging of colorectal mucosa in cancer development

Sheetal Hardikar, Biljana Gigic, Jacob K Kresovich, Victoria Damerell, Caroline Himbert, Jennifer Ose, Adetunji T Toriola, David Shibata, Christopher I Li, Jane C Figueiredo, Doratha A Byrd, Erin M Siegel, Christoph Kahlert, Alexander Brobeil, Peter Schirmacher, Cornelia M Ulrich, Timothy M Barrow

Abstract Background The past decade has seen the development of epigenetic models of aging that accurately estimate chronological age and predict disease incidence and mortality. These estimates are modulated by lifestyle and environmental factors linked to carcinogenesis, but to date this has primarily been studied in blood. Methods We examined epigenetic aging in normal colonic tissue (n = 96), adjacent mucosa (n = 245) and tumors (n = 208), using models trained on age (Horvath, Hannum, Zhang), mortality (PhenoAg …

25.08.2026journal-article

OTJR: Occupational Therapy Journal of Research

Factors Impacting Quality of Life in People Living With Complex Regional Pain Syndrome

Gretchen L. Bachman, Tara Packham, Dana S. Mills, Margo Kreger

Relationships among pain, sleep, and occupational engagement are well known; however, evidence on these relationships relative to quality of life (QOL) remains limited. This study examines pain, sleep, and occupational engagement (including social-emotional contexts) as predictors of QOL in persons with complex regional pain syndrome (CRPS). This descriptive survey research was conducted over 5 months. Participants were recruited through three organizations and were aged 18 or older, diagnosed with CRPS, English-sp …