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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
27.08.2026journal-article

International Journal of Reproduction, Contraception, Obstetrics and Gynecology

Lifestyle modifications before medicines: early intervention in adolescent polyendocrine metabolic ovarian syndrome

Neeti Gupta, Megha Agrawal, Suchismita Das

Background: Polycystic ovary syndrome (PCOS) is a common endocrine disorder. Recently its name has been changed as polyendocrine metabolic ovarian syndrome (PMOS), However, the term PCOS is inaccurate, implying pathological ovarian cysts, obscuring diverse endocrine and metabolic features, delayed diagnosis, fragmented care, and stigma. So, in this study PMOS term will be used instead of PCOS but references will be used for PCOS term because newer studies are less with new terms. PMOS is characterized by hyperandro …

27.08.2026journal-article

Philosophical Transactions of the Royal Society B: Biological Sciences

Functions of the EGFR in health and disease

Thomas Bauer, Martin Holcmann, Maria Sibilia

Abstract The epidermal growth factor receptor (EGFR) is a critical mediator of cellular physiology, and its deregulation is implicated in a broad spectrum of pathological conditions, ranging from skin disorders to epithelial malignancies and brain tumours. Although lack of EGFR signalling primarily affects skin and brain development and tissue homeostasis, aberrant EGFR activation through overexpression or mutation converts the receptor into a potent oncogenic driver. This occurs particularly in human cancers such …

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27.08.2026journal-article

Journal of Health Organization and Management

Hospital work environment and perceived workforce productivity: a structure–process–outcome perspective from Thailand's healthcare sector

Zulfiqar Ali Jumani, Tachaya Sangkakool, Ruengrumpa Intaraksa, Chila Kaewpraek, Thitika Kaewsomwong

Purpose This study examines how hospital environmental conditions influence perceived workforce productivity through the mediating roles of organizational support and job satisfaction. Grounded in Donabedian's structure–process–outcome (SPO) framework and informed by motivational theory, the study conceptualizes productivity as an organizational outcome shaped by structural and psychosocial processes rather than as a purely technical measure. Design/methodology/approach A quantitative, cross-sectional survey was co …

27.08.2026journal-article

Developmental Medicine & Child Neurology

Deep brain stimulation outcomes and management of childhood‐onset dystonia and associated hyperkinetic movements disorders

Sinead Barkey, Laura Ainaga, Eva Maria Navarrete Muñoz, Verity McClelland, Keyoumars Ashkan, Richard Selway, Harutomo Hasegawa, Daniel E Lumsden, Jean‐Pierre Lin, Hortensia Gimeno

Abstract Aim To examine longitudinal changes in self‐selected goals and dystonia severity over 1 year, 2 years, and 5 years after deep brain stimulation (DBS) in children and young people (CYP) with dystonia and other hyperkinetic movement disorders, using CYP and caregiver reports. Method The retrospective cohort study included follow‐up to 5 years after DBS, with the number of participants varying across time points. In the CYP group, 62 participants were included at the 1‐year follow‐up, 50 at 2 years, and 17 at …

27.08.2026journal-article

Population, Space and Place

Boomerang Young Adults in Seoul, South Korea: Residential Pathways, Health and Social Attitudes

Gum‐Ryeong Park, Jiawei Wu

ABSTRACT Leaving the parental home is a key transition to adulthood. However, recent sociodemographic changes have produced more diverse residential pathways such as delayed home‐leaving or returning to the parental home (‘boomerang movers’). While prior research has focused on the characteristics and determinants of these patterns, few studies have examined how various residential pathways are related to trajectories of health and social attitudes in Korea. We used longitudinal data from the annual Seoul Young Adu …

27.08.2026journal-article

Clinical Journal of Health Sciences

Investigation of the Relationship Between Psychopathological Symptoms, Acculturation, and University Adjustment Among Students from Eastern and Western Türkiye Studying in the TRNC

Merve Nehir Kurt, Mehmet Çakıcı, Atakan Taşkıran

The aim of this study was to compare the acculturation attitudes, university adjustment levels, and psychopathological symptoms of university students from the eastern and western regions of Türkiye studying in the Turkish Republic of Northern Cyprus (TRNC), and to examine the relationships among these variables. This descriptive cross-sectional study included a total of 100 university students enrolled at Near East University, comprising 50 students from the eastern regions and 50 students from the western regions …

27.08.2026journal-article

BMC Psychology

Associations of war-related displacement and reintegration with mental health and academic experiences among university students in Lebanon: a cross-sectional study

Samer A Kharroubi, Rouba Ballout

Abstract Background The escalation of war in Lebanon has severely impacted many aspects of daily life, with university students particularly affected in terms of their mental health and academic experiences. This study aimed to examine the effects of the war, with a focus on displacement and reintegration, on students’ mental health and academic outcomes, using the American University of Beirut (AUB) as a case study. Methods Data was collected from AUB students using a cross-sectional, self-administered online surv …

27.08.2026journal-article

BMC Oral Health

Evaluation of activated irrigation techniques for the removal of calcium hydroxide from simulated internal root resorption cavities: an in vitro comparative study

Amira Shafie Ibrahim Mohamed, Dalia Mohamed Mukhtar Fayyad, Dalia Abd-Allah Mohamed

Abstract Background This study aimed to compare the calcium hydroxide [Ca(OH)₂] removal efficiency of six irrigation‑activation techniques and conventional syringe irrigation (control) from simulated internal root‑resorptive cavities in vitro. Materials and methods Seventy single-rooted human teeth were standardized to a length of 18 mm, prepared, and split longitudinally. A standardized hemispherical resorptive cavity was created in each root half; the halves were then reassembled and filled with premixed Ca(OH)₂. …

27.08.2026journal-article

Health Research Journal of Indonesia

Faktor-Faktor yang Mempengaruhi Kepatuhan Terhadap Pengobatan di Komunitas Pedesaan : Peran Pengetahuan, Dukungan Keluarga, dan self eficacy

Raya Raya, Bayu Budi Laksono

Kepatuhan terhadap pengobatan merupakan faktor penting dalam pengendalian hipertensi. Faktor kognitif dan psikososial, seperti pengetahuan, dukungan keluarga, dan self-efficacy, diduga berperan dalam membentuk kepatuhan pasien, khususnya di komunitas pedesaan. Tujuan penelitian ini adalah untuk menganalisis hubungan pengetahuan, dukungan keluarga, dan self-efficacy dengan kepatuhan terhadap pengobatan pada pasien hipertensi di komunitas pedesaan wilayah kerja Puskesmas Lamunti. Penelitian menggunakan desain survei …

27.08.2026journal-article

Journal of the American Heart Association

Socioeconomic Position in Early Life and Childhood Cardiovascular Health Measures: An International Cross‐Cohort Study

Kavindi Gamage, Susanna Pätsi, Tong Chen, Kate Mooney, Sylvain Sebert, Naomi Priest, Toby Mansell, David Burgner, the Barwon Infant Study Investigator Group

Background Cardiovascular disease is socioeconomically patterned, and risk accrues from early life. Evidence in younger populations is scarce. We investigated the extent to which early life socioeconomic position is associated with cardiovascular health in children and adolescents, and the extent of mediation by body mass index. Methods We analyzed 5 longitudinal birth cohorts: BIS (the Barwon Infant Study; Australia; mean age 4.1 years; n=708); BiB (Born in Bradford; United Kingdom; mean age 9.3 years; n=4576); LS …

27.08.2026journal-article

Hospital Pediatrics

Development and Validation of a Prediction Model for Alarm-Triggered Interventions in Pediatrics

Shogo Akahoshi, Shun Nagasawa, Mana Sakatani, Hidehiro Minegishi, Nanako Kawata, Kazuki Iio, Kentaro Fukuda, Akiko Kinumaki, Hiroshi Hataya, Funato Sato, Tetsuji Kaneko, Yoshihiko Morikawa

BACKGROUND Alarm fatigue in pediatric wards stems from frequent, nonactionable alarms that do not lead to clinical intervention. Predicting alarm-triggered clinical interventions is essential for optimizing monitoring strategies. OBJECTIVE To identify factors associated with alarm-triggered interventions and to develop a predictive model to reduce the alarm burden through an action-oriented approach. METHODS This prospective cohort study was conducted in 2 pediatric wards of a tertiary hospital (2018-2019). A perso …

27.08.2026journal-article

The Journals of Gerontology, Series B: Psychological Sciences and Social Sciences

Associations between indicators of self-rated health, cognitive function, risk of cognitive impairment, and dementia: A coordinated data analysis

Eileen K Graham, Kayla Garner, Emorie D Beck, Kathryn L Jackson, Jing Luo, Gabrielle N Pfund, Tomiko Yoneda, Rongxin Cheng, Adam Nissen, Anne Zola, Chloe Fawns-Ritchie, Lily Pieramici, Winnie Wang, Stephen Antonoplis, Philip J Batterham, Tom Booth, Raul A España, Matthew J D Pilgrim, Christopher Beam, Katherina K Hauner, Andrew Steptoe, Elizabeth Zelinski, Simon R Co, Martijn Huisman, William J Chopik, Daniel K Mroczek

Abstract Objectives A growing body of literature suggests that self- or patient- reported health may be associated with objective health outcomes. Self-reported health could thus be a non-invasive and low-cost way of identifying who is at risk of poor health in later life. However, no prior study has systematically examined this relationship using multiple large datasets. The goal of the current study was thus to examine the extent to which self-rated health was associated with cognitive function, a distinct outcom …

27.08.2026journal-article

Journal of Adolescent Research

“We Have Always Created Paths”: Learning From Black Girls About Navigating Intersectional Oppression

Ana Vasan, Leoandra Onnie Rogers

The present study explored the ways in which adolescent Black girls responded to oppressive stereotypes and expectations based on their racial, gender, and intersectional (race-x-gender) identities. Participants included 60 girls who were students at a predominantly Black, all-girls high school ( M age = 16.17 years) and completed a 1:1 semi-structured interview about their identity experiences. Expanding on existing research that offers modes of responding to oppression that are dichotomized and value-laden (i.e., …

27.08.2026journal-article

Population, Space and Place

Healing at Home or Re‐Marginalisation? Perceived Neighbourhood Environment, Sense of Belonging and Mental Health of Return Migrants in Peri‐Urban China

Lingling Su, Enyu Chang

ABSTRACT Amidst China's transition into a new phase of urbanisation, the mental health of return migrants has emerged as a critical issue. Whether returning to rural communities offers the spiritual solace of ‘healing at home’ or precipitates a descent into ‘re‐marginalisation’ remains poorly understood, particularly in metropolitan peri‐urban villages where remembered hometowns are being reshaped by urbanisation. Drawing on the survey of return migrants in peri‐urban Zhengzhou, this study constructs and validates …

27.08.2026journal-article

Med Phoenix

Association between Physical Activity and Mental Health among School Going Adolescents in Dhulikhel: A Cross-sectional Study

Smita KC, Prakash KC, Tenzing Norbu Lama

Introduction: Physical activity (PA) is important for both physical and mental health. However, many adolescents face mental health problems due to academic pressure, increased screen time, and lack of physical activity. The aim of the study was to find out the association between of physical activity and the presence of depression, anxiety, and stress among school adolescents in Dhulikhel. Materials and Methods: A cross-sectional study was conducted among 384 students aged 14–19 years from four schools in Dhulikhe …

27.08.2026journal-article

Journal of Pharmaceutical Health Care and Sciences

Impact of interventions for adverse events by oncology pharmacists before versus after medical examination in outpatient chemotherapy: a retrospective, comparative study

Shinsaku Washinosu, Tatsuya Hayama, Akihiro Uchiike, Shinya Tsuboi, Katsuyuki Hazama, Sakae Fukushima, Kei Saito, Katsuhiro Miura

Abstract Background While pharmacist interventions improve clinical outcomes in cancer treatment, their optimal timing remains unclear. To address psychological barriers to modifying prescriptions during conventional post-examination interventions, we shifted to a proactive, pre-examination approach. This study evaluated the impact of this proactive management on clinical outcomes in outpatients receiving chemotherapy. Methods We conducted a retrospective, comparative study of pharmacist interventions for chemother …

27.08.2026journal-article

Qualitative Health Research

Lived Experiences of Women Navigating End-of-Life Caregiving and Parenting During the COVID-19 Pandemic

Junhee Baek, Faye Ajmera, Paige Chu, Eryn Tong, Sally Bean, Breffni Hannon, Elie Isenberg-Grzeda, Madeline Li, Gary Rodin, Debbie Selby, Camilla Zimmermann, Sarah Hales, Rinat Nissim

The COVID-19 pandemic intensified the burden on informal caregivers, particularly those with dual caregiving roles. This grounded theory study explores the lived experiences of women who simultaneously cared for a hospitalized family member at the end of life and for minor children during the pandemic. We aimed to examine how the intersection of these roles influenced women’s experiences during caregiving and into bereavement. We analyzed 11 qualitative interviews with bereaved women caregivers in Toronto, Canada, …

27.08.2026journal-article

Brazilian Journal of Implantology and Health Sciences

MANEJO ODONTOLÓGICO DE CRIANÇAS COM TRANSTORNO DO ESPECTRO AUTISTA

Ana Paula Martins Melo, Letícia Gabriela de Almeida Freitas, Maria Izabel de Mendonça Alves

O Transtorno do Espectro Autista (TEA) é uma condição do neurodesenvolvimento caracterizada por alterações na comunicação e interação social, padrões restritos e repetitivos de comportamento, além de alterações sensoriais que podem comprometer significativamente a adaptação do indivíduo aos diferentes ambientes, incluindo o consultório odontológico. Em pacientes pediátricos, essas características podem dificultar o atendimento clínico, tornando necessária a adoção de estratégias específicas de manejo comportamental …

27.08.2026journal-article

Brazilian Journal of Implantology and Health Sciences

Análise transversal dos fatores associados à autopercepção ruim da saúde (2006-2024)

Arthur Novaes Tucunduva, João Pedro Constantino Bottura, Helena Pirani Bazi, Maria Luíza Angeli Manoel, Catarina Barbieri Raduan Miguel, Allana Flores Volpi, Paulo Gabriel Da silva Beckmann, Herika Paula Santana Soares, Gabriel Teixeira Campos Leite, Caio Yukio Fernandes Miada, Luiz Guilherme Marin Ledesma Pereira, Samuel Consiglieri Ferraz, Eric Donadoni Rugno, Márcio Hideki Kodani Junior, Enzo Novaes Tucunduva

Introdução: objetiva-se analisar os fatores correlacionados à autopercepção negativa da saúde, que compreende importante indicador de saúde. Metodologia: trata-se de estudo transversal com amostra de 833.217 adultos (≥ 18 anos). A autopercepção negativa da saúde representa o desfecho que será comparado com covariáveis como insônia e depressão, entre outras. Resultados: a amostra apresentou idade média de 47,8 anos (DP = 17,9) e prevalência de autopercepção ruim de saúde de 4,9% (n = 41.002). Observaram-se prevalênc …

27.08.2026journal-article

Healthcare

Development and Psychometric Evaluation of the Military Cadets’ Mental Health Risk Scale (MCMHRS) in Chinese Military Academy Cadets

Feifei Wang, Jia Guo, Guoyu Yang

Background: Military academy cadets face training, study, and adaptational pressures that elevate the risk for mental health problems and functional impairment. Existing tools are either generic symptom checklists or narrow resilience scales; none integrates environmental risk, individual vulnerability, and protective resources within a unified hierarchical model relevant to this population. Methods: We developed and psychometrically evaluated the Military Cadets’ Mental Health Risk Scale (MCMHRS). After item gener …

27.08.2026journal-article

Frontiers in Pediatrics

Association between placental histological chorioamnionitis and respiratory distress syndrome in preterm infants: a retrospective cohort study

Hua Ke, Dong Yang, Liangjuan Zhang, Chengyin Liu

Objective To evaluate the independent association between placental histological chorioamnionitis (HCA) and respiratory distress syndrome (RDS) in preterm infants and explore whether this association varied by gestational age and histological stage. The incremental predictive value of HCA beyond gestational age and birth weight was also assessed. Methods This single-center retrospective cohort study included 689 preterm infants born at <34 weeks of gestation between June 2020 and June 2025 with definitive placen …

27.08.2026journal-article

Nursing & Health Sciences

Walking Together: A Cross‐Cultural Study of the Relationship Between Religiosity and Substance Use Disorder

Camila Chagas, Leonardo Breno Martins, Tassiane Cristine Santos de Paula, Wellington Zangari, José Carlos Fernandes Galduróz

ABSTRACT The literature suggests that religiosity is a protective factor for substance use. However, individuals with substance use disorder (SUD) may actively cultivate their religiosity during substance use. This qualitative study analyzed the perceptions and meanings homeless people attribute to their substance use trajectories and religiosity, as well as the potential connections between these two themes. The analysis was conducted based on the content analysis technique proposed by Bardin. A total of 40 semi‐s …

27.08.2026journal-article

Sexual Health

Prevalence and risk factors of current hepatitis C infection among men who have sex with men aged 20–59 years: NHANES 1999–2016

Yan Zhang, Jiewei Liu, Yihao Lin, Agins Bruce, Yangyang She, Hongbo Jiang

Background Men who have sex with men (MSM) are a key population with a higher prevalence of hepatitis C virus (HCV) infection than the general population. Our study estimated the prevalence of current HCV infection and identified risk factors among MSM aged 20–59 years in the US from 1999 to 2016. Methods Data were obtained from the 1999–2016 National Health and Nutrition Examination Survey (NHANES). Current HCV infection was defined as having a positive HCV RNA test result. The prevalence of current HCV infection …

27.08.2026journal-article

Journal of Eating Disorders

Improvements in sleep, weight, and eating-disorder symptoms following off-label leptin treatment in an adolescent with chronic anorexia nervosa and insomnia: a case report

Alexander Dück, Hang Zhu, Judith Melinat, Monika Kruzer, Christoph Berger, Michael Kölch, Martin Reinhardt, Hannes Brehme, Annelie Zimmermann, Linda Frintrop, Olaf Reis

Abstract We report off-label administration of human recombinant leptin (metreleptin) over a 12-day period in a 17-year-old female adolescent with chronic anorexia nervosa (AN) and clinically significant insomnia. Two observation windows are distinguished throughout: a short-term window between day 1 (pre) and day 12 (post) of dosing, and a longer-term window between day 12 and the two-month follow-up (d + 60), capturing both changes temporally associated with leptin administration and the course of continued weigh …