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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
28.08.2026journal-article

Frontiers in Digital Health

An LLM-supported just-in-time adaptive intervention delivered by a socially assistive robot for cognitive training in mild cognitive impairment: study protocol for an assessor-blinded randomized controlled trial

Jingzheng Yan, Yahui Cheng, Yaning Wang, Yingjuan Cao

Background Mild cognitive impairment (MCI) is a clinically important stage at which non-pharmacological interventions may help preserve cognitive function and daily functioning. Existing digital cognitive training programs are often limited by static task progression, declining engagement, and insufficient responsiveness to moment-to-moment cognitive and emotional states. Objective This study protocol describes a single-center, parallel-group, assessor-blinded randomized controlled trial evaluating an adaptive cogn …

28.08.2026journal-article

Frontiers in Education

Comprehensively understanding K-12 teachers’ occupational health: a convergent mixed-methods exploration of stress and wellbeing

Cynthia A. Wiltshire, Christopher J. McCarthy, Caroline Weppner, Richard G. Lambert, Yijie Tian

Stress has detrimental impacts on K-12 teachers’ occupational health, yet there is no consensus on how best to define and measure it. As such, the present study implemented quantitative and qualitative methodologies, including a physiological measure of stress, to comprehensively assess and understand teacher stress in one independent school district in the southern United States. Forty-four public school teachers participated by completing self-reported measures of stress and occupational health, providing a hair …

28.08.2026journal-article

World Journal of Radiology

Imaging-guided adaptive radiation therapy in limited-stage small cell lung cancer: Current evidence and clinical perspectives

Omer Sager

Small cell lung cancer (SCLC) remains among the most aggressive thoracic malignancies and continues to present major therapeutic challenges despite advances in multimodality treatment. Limited-stage SCLC (LS-SCLC), representing approximately one-third of cases, is conventionally managed with concurrent chemoradiotherapy delivered with curative intent. Radiation therapy (RT) is central to treatment; however, rapid treatment related anatomical and volumetric changes may alter target geometry and reduce the accuracy o …

28.08.2026journal-article

Russian Journal of Clinical Dermatology and Venereology

Tacrolimus ointment: a selective T-cell immunosuppressant in dermatology

S.I. Bobko, D.D. Petrunin, V.S. Dolgikh, D.V. Nazarenko, A.M. Zemskov, M.A. Zemskov

Tacrolimus ointment is a topical calcineurin inhibitor with potent anti-inflammatory activity that suppresses T-cell activation and the production of pro-inflammatory cytokines. Unlike topical glucocorticosteroids, the drug does not cause skin atrophy and epidermal thinning, making it particularly valuable for long-term use in steroid-sensitive areas — such as the face, skin folds, and the anogenital region. In addition to its primary anti-inflammatory effect, tacrolimus ointment possesses clinically significant an …

28.08.2026journal-article

Stroke

Prevalence and Clinical Relevance of Antiphospholipid Antibodies in Ischemic Stroke: A Systematic Review and Meta-Analysis

Nathan W. Watson, Syed Bukhari, Sina Rashedi, Mariana Pfeferman, Francisco Ujueta, Bassil Bacare, Brittany N. Weber, Mehrdad Zarghami, Yogendra Kanthi, Eric A. Secemsky, Jean M. Connors, Geoffrey D. Barnes, Sacha Uljon, Samuel Z. Goldhaber, Jeffrey I. Weitz, Karen H. Costenbader, Harlan M. Krumholz, Gregory Piazza, Mary Cushman, Christopher D. Anderson, Mitchell S. V. Elkind, Behnood Bikdeli

BACKGROUND: Antiphospholipid antibodies (aPL) are associated with an increased risk of thrombosis. However, individual studies have reported conflicting findings regarding the prevalence of aPL in patients with ischemic stroke and their association with first or recurrent events. METHODS: Systematic searches of PubMed and Embase through May 13, 2025 were conducted to identify case-control, cohort, or cross-sectional studies investigating 3 questions related to aPL seropositivity (defined as positivity for either im …

28.08.2026journal-article

Journal of Engineering Research and Reports

Secure Artificial Intelligence for Asset Performance in Critical Infrastructure: A Critical Narrative Review of Safety, Operational Excellence and Continuous Quality Improvement

Adeyemi Adebukunola Ishekwene, Christopher Ugbong Akeke, Akinde Michael Ogunmolu, Busola Motunrayo Olawale, Cornelia Ifeoma Ejoh

Critical infrastructure operators increasingly deploy artificial intelligence (AI) to detect degradation, predict failures, optimise maintenance, identify cyber anomalies and support operational decisions. These capabilities create a plausible route to higher availability, reliability and quality, yet they also couple asset-performance decisions to data integrity, model uncertainty, software supply chains, human oversight and operational technology security. This critical narrative review examines how secure AI can …

28.08.2026journal-article

Arqueología y Territorio Medieval

Aromacología y salud: usos terapéuticos del perfume y cultura material entre las mujeres nazaríes (siglos XIII-XV)

Alba Abdel-fatah Martínez

In Nasrid society of the 13th and 14th centuries, perfumes and aromatic substances not only played an important symbolic and cultural role but also had therapeutic and health-related purposes, especially in women’s lives. This study analyses the use of aromatic remedies in women’s body care, connecting these practices with evidence from material culture, such as the perfume containers in the Alhambra Museum.Based on the analysis of Ibn al-Khatib’s medical texts and archaeological finds, the therapeutic uses of perf …

28.08.2026journal-article

Frontiers in Artificial Intelligence

Structured proxy features for multimodal NSCLC survival prediction from pretreatment CT

Huu Phong Nguyen, Delower Hossain, Ehsan Saghapour, Zhandos Sembay, Jake Y. Chen

Introduction Lung cancer results in roughly 1.8 million fatalities annually worldwide, with non-small cell lung cancer (NSCLC) comprising the majority of cases. Despite advancements in treatment, survival stratification remains challenging due to intratumoral heterogeneity inadequately captured by conventional descriptors. Standard radiomic and deep learning techniques regard imaging features as independent quantities, overlooking structured interactions between tumor characteristics. We evaluate whether structured …

28.08.2026journal-article

Scientific Reports

A large-scale integrated optical phased array with digital beamforming

Volkan Gurses, Debjit Sarkar, Aroutin Khachaturian, Reza Fatemi, Ali Hajimiri

Abstract Digital signal processing has driven much of the capacity growth in coherent fiber-optic communications, but its use in free-space coherent imagers and sensors has so far been limited. We report a 128-element optical phased array with a fully parallelized readout that performs beamforming in the digital domain at 1550 nm. The photonic integrated circuit consists of an array of waveguide grating antennas, each routed to its own balanced coherent receiver, with a common on-chip local oscillator delivered to …

28.08.2026journal-article

Management in Education

Digital leadership as a mediator in the relationship between digital transformation and quality of work life among primary school teachers in the Al-Jouf region

Ohud Abdulrahman Aldaghmi, Sanaa Mostafa Mohammed, Reda Ebrahim Mohamed Elashram

Despite growing research interest in digital transformation in education, the mechanisms through which institutional technological change translates into improvements in teachers’ professional quality of life remain insufficiently explored, particularly within Arab educational contexts. This study investigated the mediating role of digital leadership in the relationship between digital transformation and quality of work life among primary school teachers in the Al-Jouf region, Saudi Arabia. A quantitative descripti …

28.08.2026journal-article

Journal of Clinical Medicine

Comment on Inghilleri, G.; Franchini, M. Hypophosphatemia in Patients Receiving Intravenous Iron Supplementation for Iron-Deficiency Anemia: A Narrative Review. J. Clin. Med. 2026, 15, 4748

Ceren Çevik, Nur Düzen Oflas, Kamil Konur, Gökhan Tazegül, Nurhayat Özkan Sevencan, Muhammet Özbilen

We read with great interest the narrative review by Inghilleri and Franchini about hypophosphatemia in patients receiving intravenous iron supplementation for iron-deficiency anemia [...]

28.08.2026journal-article

Clinical Cancer Research

Feasibility and Activity of Concurrent Neoadjuvant Chemotherapy and Radiotherapy in Patients with High-risk Soft-Tissue Sarcoma

Elena Palassini, Sara Pizzamiglio, Emanuela Palmerini, Vittorio Quagliuolo, Javier Martin-Broto, Antonio Lopez Pousa, Sandra Aliberti, Antonella Brunello, Jean-Yves Blay, Oscar Tendero, Robert Diaz Beveridge, Virginia Ferraresi, Iwona Lugowska, Claudia Sangalli, Sandro Pasquali, Valeria Duroni, Giuseppe Bianchi, Davide Maria Donati, Andrea Marrari, Jean Michel Coindre, Silvia Bagué, Valeria Fontana, Carlo Morosi, Silvia Stacchiotti, Angelo Paolo Dei Tos, Paolo Verderio, Paolo Giovanni Casali, Alessandro Gronchi

Abstract Purpose: The ISG-STS 1001 was an international, randomized, phase III trial for localized, high-risk, soft-tissue sarcoma comparing neoadjuvant chemotherapy (ChT) with epirubicin and ifosfamide (EI) versus a histology-tailored regimen. The trial also included a cohort of patients not randomized but just registered and treated with EI. In this study, we analyzed the tolerability and activity of concurrent EI and radiotherapy (RT) in the ISG-STS 1001 trial. Patients and Methods: EI consisted of epirubicin 12 …

28.08.2026journal-article

Journal of Continuing Education in the Health Professions

A Skills-Based Longitudinal Intervention for Clinician Educators: Addressing Implicit Bias in Patient Care and the Clinical Learning Environment

Hana Khidir, Savanna Carson, Stefanie Vassar, Arash Nafisi, Gezman Abdullahi, Sural Shah, Hrishikesh K. Belani, Benjamin P. L. Meza, Arleen F. Brown, Cristina M. Gonzalez

Introduction: Implicit bias contributes to health care disparities. Addressing implicit bias is one focus of health professions education and learners desire instruction in the topic. Few faculties received skills-based instruction in addressing implicit bias during their own education and training and often feel ill-equipped to facilitate this instruction. Recognizing faculty are both learners and teachers in addressing implicit bias, the authors developed a longitudinal faculty development program informed by the …

28.08.2026journal-article

APIK Journal of Internal Medicine

Clinical Profile of Elderly Women in a Rural Area and the Impact of Health Service Camps

S. Karthik, Anand P. Ambali

Abstract Background: The elderly population is increasing, placing a greater strain on the healthcare system. In India, 71% of older adults live in rural areas. Elderly women outnumber men and face challenges related to the availability, affordability, and accessibility of health care. Understanding their profiles is essential to addressing these issues. This paper provides an overview of elderly women who visited our monthly camp, “Reaching the Unreached.” Objectives: To assess the clinicodemographic profile and t …

28.08.2026journal-article

International Journal for Quality in Health Care

Medication reconciliation documentation and documented discrepancies in a tertiary Saudi hospital: a retrospective observational study

Ashwaq H Alharthi, Marwan A Alrasheed, Yahya M Tawfik, Sara Z Almutairi, Aliyah Y Almobarak, Yousif A Asiri

Abstract Introduction Medication reconciliation is a key patient-safety process during transitions of care, but its routine documentation and associated medication-list findings are not well described in Saudi tertiary hospital practice. This study aimed to characterize medication reconciliation documentation, documented medication discrepancies, and documented medication-list modifications at King Saud University Medical City (KSUMC). Methods A retrospective observational study was conducted using routinely collec …

28.08.2026journal-article

International Journal of Healthcare Information Systems and Informatics

A Virtual Reality-Based Personalized Health Informatics System for Home Fitness and Sustainable Physical Health Promotion

Qingyang Yu

This study designed a personalized virtual reality health informatics system for home fitness and public health promotion. Built on a closed-loop informatics framework, the system integrated user profiling, real-time motion capture, adaptive feedback, and dynamic training adjustment to address poor personalization, low adherence, and insufficient guidance in conventional home exercise. Using virtual reality interactive technology and multidimensional data analysis, it delivered tailored programs, corrected movement …

28.08.2026journal-article

Brazilian Journal of Implantology and Health Sciences

Revisão Integrativa sobre aplicação de ácido hialurônico para fechamento de black triangles

José Cássio de Almeida Magalhaes, Lucca Barros de Martini, Fernando Martins Baeder, Gustavo Duarte Mendes, Elaine Marcílio Santos, Vittória Gomes, Ana Paula Taboada Sobral, Henrique Nogueira, Marcela Letícia Leal Gonçalves, Taianny Monteiro, Paola Fernanda Leal Corazza, Gabriela Traldi Zaffalon

A perda da papila interdental é um problema estético e é frequentemente referida como triângulos negros. Os triângulos negros podem ser consequência de periodontite, tratamento ortodôntico e diferenças anatômicas devido aos efeitos desses fatores na distância crítica entre o ponto de contato e a crista óssea. O espaço interproximal visível na região cervical abaixo do ponto de contato, que é causado pelo preenchimento incompleto da fenda pela papila interdental, desempenha um papel muito importante na estética do s …

28.08.2026journal-article

Online Information Review

ADHD in the digital age: exploring the well-being of adults with attention difficulties in Facebook support groups

Michal Isser, Tali Gazit

Purpose Facebook support groups provide opportunities for emotional support and social connection among individuals with shared health conditions. This study examined the relationships among online engagement, perceived social support, self-compassion and well-being among adults with attention difficulties (ADHD) participating in Facebook groups. Design/methodology/approach The sample included 405 adults who reported having ADHD or attention difficulties, recruited from two types of Facebook groups: members of ADHD …

28.08.2026journal-article

Scientific Reports

Enhancing clinical reasoning and diagnostic precision through scaling laws and multi-stage supervised fine-tuning in open-weight medical large language models

Lukasz Pawlik, Stanislaw Deniziak

Abstract The emergence of large language models offers unprecedented opportunities to transform clinical workflows. However, reliance on proprietary closed-source models poses significant risks to data privacy, institutional autonomy, and reasoning transparency. This study investigates the optimization of open-weight architectures, specifically the Llama-3.1-8B and Qwen2.5-14B-Instruct families, to function as specialized diagnostic tools rather than general-purpose conversational agents. Utilizing the MedQA USMLE- …

28.08.2026journal-article

Health Research Journal of Indonesia

Hubungan Pola Asuh Orang Tua dengan Perilaku Picky Eating pada Anak Usia Prasekolah di TK Islam Bakti Kauman Batang

Hesti Fathan Nurfais Fauziah, Fatikhah, Penthatasya, Yulia Ardiyanti

Latar Belakang: Picky eating merupakan salah satu masalah perilaku makan yang sering dijumpai pada anak usia prasekolah dan berkaitan dengan kecukupan asupan gizi serta pertumbuhan anak. Pola asuh orang tua merupakan aspek pengasuhan yang sering dikaji dalam hubungannya dengan perilaku makan anak, namun hasil penelitian sebelumnya masih menunjukkan temuan yang belum konsisten. Tujuan: Menganalisis hubungan pola asuh orang tua dengan perilaku picky eating pada anak usia prasekolah di TK Islam Bakti Kauman Batang. Me …

28.08.2026journal-article

Digital Policy, Regulation and Governance

From diffusion to internalization: digital policy, data institutions and eco-environmental governance performance in China

Zexin Lin, Pingyang Liu

Purpose This study aims to examine whether and under what conditions digital policy interventions are associated with stronger eco-environmental governance performance (EGP). Focusing on China’s National Big Data Comprehensive Pilot Zone (NBDCPZ) policy, it investigates how policy-induced digital-capacity expansion and data-governance conditions shape the spatial realization of governance returns, with particular attention to data openness, data circulation and their institutional complementarity in the shift from …

28.08.2026journal-article

Aquichan

Inadequate Self-Efficacy in Health: A Conceptual Analysis

Isabela Mendonça Rodrigues dos Santos, Diogo Matheus Barros da Silva, Maria Neyrian de Fatima Fernandes, Francisco Mayron Morais Soares, Isaura Leticia Tavares Palmeira Rolim

Introduction: Self-efficacy is a psychological construct developed by Bandura that is widely used in the health sciences; it refers to an individual’s belief in their ability to organize and perform the actions necessary to cope with future situations. In contrast, although inadequate self-efficacy is often described as a limited individual perception, it remains relatively undefined in the literature. Objective: To conduct a conceptual analysis of the term ‘inadequate health self-efficacy, focusing on its applicab …

28.08.2026journal-article

Business Information Review

AI literacy as an extension of digital literacy: A conceptual framework for knowledge work in AI-enabled organizations

Kha Huy Tran

Artificial intelligence (AI) is increasingly embedded in organizational information environments, reshaping how knowledge is created, interpreted, and applied. As AI systems become active participants in organizational information processes, employees are required not only to operate digital technologies but also to interpret algorithmic outputs and collaborate effectively with intelligent systems. While prior research has extensively examined digital literacy, human–AI collaboration, and AI literacy, these streams …

28.08.2026journal-article

International Journal of Public Health and Medical Research

Analysis on Cost-effectiveness and Budget Impact of Health Technology Assessment in Critical Care Medicine from the Global Health Perspective

Xuan Wang

Critical care medicine is relatively expensive in terms of medical resources. Cost-effectiveness analysis (CEA) and its subset, cost-utility analysis (CUA), are employed in health technology assessment (HTA) to determine the economic value of intervention measures, and a separate budget impact analysis is performed to assess how the introduction of new technology will affect the budget. Both are used to make selections. This paper reviews the progress of health technology assessment (HTA) in the field of global cri …