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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
20.08.2026journal-article

Healthcare

Effects of a Fully Immersive Virtual Reality Exercise Game on Fear of Movement, Pain, and Disability in People with Chronic Non-Specific Low Back Pain: A Pilot Randomized Controlled Trial

Hana Alsobayel, Kholoud Almufaireej, Dalia Alimam, Hamad Alduaij, Afaf Shaheen, Hend Al-Khalifa

Background/Objectives: Low back pain (LBP) is a leading cause of disability worldwide, and exercise-based rehabilitation is recognized as an effective management strategy. However, adherence to exercise remains challenging. Fully immersive virtual reality (VR) exercise interventions may enhance engagement and clinical outcomes. This study aimed to examine the effect of a fully immersive VR exercise game on pain, fear-avoidance beliefs, and disability in individuals with chronic non-specific LBP. Methods: A single-b …

20.08.2026journal-article

American Journal of Speech-Language Pathology

A Qualitative Evidence Synthesis of Communication Partner Training: Exploring the Experiences of Communication Partners and People With Acquired Brain Injury

Nicholas Behn, Iben Christensen, Ian Kellar, Leanne Togher, Katerina Hilari, Madeline Cruice

Purpose: This study aimed to explore the experiences of adult communication partners (CPs) of individuals with acquired brain injury (ABI) who received communication training and, where reported, the experiences of individuals with ABI who attended or participated in the training. Method: A qualitative evidence synthesis was conducted. Electronic searches were completed in CINAHL Ultimate, APA PsycInfo, APA PsycArticles, Medline, Embase, AMED, Scopus, NeuroBITE, and PubMed for studies published until August 2025. I …

20.08.2026journal-article

PLOS Biology

Social interactions between people of same and different generations shape longitudinal changes in interpersonal neural synchrony, loneliness, and social connection

Ryssa Moffat, Guillaume Dumas, Emily S. Cross

Loneliness is globally acknowledged as a severe and burgeoning health risk, fueling interest in helping people of all ages form meaningful social connections. One promising approach consists of intergenerational social programs. While behavioral and qualitative evidence derived from such programs promise health and wellbeing benefits, the physiological consequences of repeated intergenerational encounters remain unknown. Insight into physiological changes will shed light on the mechanisms of social connection. We c …

20.08.2026journal-article

Surface Review and Letters

Effect of combined PM and aging treatment on the microstructural evolution and corrosion resistance of NiTi alloys

Qusay Abdulsattar Mohammed, Sokhiba Israilova, Akanksha Mishra, Ripendeep Singh, F. Nie

Nickel–titanium alloys produced through powder metallurgy were subjected to controlled aging treatments to examine how thermal exposure influences microstructural evolution, oxide formation, and corrosion performance. Aging at 600 °C for 1–3 h progressively reduced porosity and promoted the development of intermetallic phases such as Ni 3 Ti, Ni 4 Ti3, and Ti 2 Ni, along with increasingly uniform TiO 2 surface layers. SEM, EDS, and XRD analyses confirmed enhanced oxide coverage and phase redistribution with longer …

20.08.2026journal-article

Pathogens

Patient-Level Discordance Between SCORE2 Cardiovascular Risk and PD-1/PD-L1 Checkpoint-Expression Profiles in People Living with HIV: A Secondary Cohort Analysis

Bogusz Aksak-Wąs, Karolina Skonieczna-Żydecka, Danuta Cembrowska-Lech, Miłosz Parczewski, Filip Lewandowski, Karol Serwin, Kaja Mielczak, Mateusz Bruss, Franciszek Lenkiewicz, Milena Rafalska-Kosior, Laura Lesiewska, Paulina Niedźwiedzka-Rystwej

Background: Conventional cardiovascular risk scores do not directly characterize immune checkpoint-expression phenotypes in people with HIV. We examined patient-level alignment between SCORE2 and PD-1/PD-L1 checkpoint expression in a secondary analysis of a previously characterized parent cohort. Methods: Data from 100 PWH followed at a single HIV center were analyzed. SCORE2, lipid parameters, systolic blood pressure, CD4+/CD8+ ratio, and flow-cytometric PD-1/PD-L1 expression on T-cell, B-cell, and NK-cell subsets …

20.08.2026journal-article

JAMA Otolaryngology–Head & Neck Surgery

TERT Promoter Variants, Older Age, and Prognosis in Papillary Thyroid Carcinoma

Vicente R. Marczyk, Sophie Li, Chia Chin Wu, Matthew A. Loberg, Ying Henderson, Meghan Martin, Sarah Hamidi, Steven Waguespack, Naifa Busaidy, Ramona Dadu, Priyanka Iyer, Mimi Hu, Victoria Banuchi, Anastasios Maniakas, Stephen Lai, Mark Zafereo, Michelle D. Williams, Sayed Mohsen Hosseini, Quanhu Sheng, George J. Xu, Eric C. Huang, Vivian L. Weiss, Maria Cabanillas, Jennifer R. Wang

Importance Older age at diagnosis is associated with worse outcomes in papillary thyroid carcinoma (PTC). The current American Joint Committee on Cancer tumor-node-metastasis staging system incorporates an age of 55 years or older as staging criteria. TERT promoter variants are also associated with aggressive disease. Objective To evaluate the interplay between age, TERT promoter variants, and survival outcomes in PTC. Design, Setting, and Participants This multi-institutional retrospective cohort study was conduct …

20.08.2026journal-article

Frontiers in Aging

Collagen-induced restructuring of astrocytes and vessels in organotypic mouse brain slices

Eva Steiner, Valentin Wolfgang, Christian Humpel

Introduction The brain exhibits high plasticity and responds to many forms of external stimuli, such as trauma, seizures, drugs, and biomaterials. Collagen is a non-toxic biocompatible protein that participates in the plastic reformation of the brain. In this study, we explored whether collagen can reconstruct astrocytes and brain vessels by using microcontact printing on organotypic mouse brain slices. Methods Organotypic brain slices from postnatal days 8–10 were prepared and connected to collagen microcontact pr …

20.08.2026journal-article

Frontiers in Psychology

The impact of therapeutic landscapes on the mental health of older adults: a systematic review

Yan Han, Bin Li, Yuxin Hou, Juan Zhang

Therapeutic landscapes, as an important form of health-promoting environmental intervention, provide a feasible approach to improving the mental health of older adults. However, their modes of action and underlying mechanisms require further clarification. Following the PRISMA guidelines, this study systematically searched Web of Science, Scopus, JSTOR, ScienceDirect, PubMed, and PsycINFO. Studies were selected according to the PICOS framework and assessed using the Crowe Critical Appraisal Tool (CCAT) and the JBI …

20.08.2026journal-article

npj Science of Food

Krill oil attenuates skeletal muscle atrophy during D-galactose-induced accelerated aging via an AMPK-dependent mechanism

Zi-Jian Wu, Xin-Yue Zhao, Yu-Hong Yang, Cheng-Cheng Wang, Yan Zheng, Shi-Xiang Wu, Cheng-Yu Yang, Han-Ni Wei, Qing-Yan Zou, Yu-Ming Wang, Lei Du

Abstract The global aging trend highlights the critical challenge of sarcopenia, which severely compromises both quality of life and overall survival time. This study aimed to investigate the effects of Antarctic krill oil (KO) on accelerated aging-induced skeletal muscle atrophy and its underlying mechanisms. An accelerated aging mouse model was established via daily intraperitoneal injection of 400 mg/kg D-galactose (D-gal) for 12 consecutive weeks. Concurrently, mice received oral gavage of KO or fish oil (FO) a …

20.08.2026journal-article

Journal of Materials Science: Materials in Engineering

Mechanical stability and degradation kinetics of a natural fiber biogeosynthetic composite from Typha domingensis and Boehmeria nivea under accelerated aging

Emersson Guedes da Silva, Luiz Diego Vidal Santos, Francisco Sandro Rodrigues Holanda, Alarico José da Silva Azerêdo, Renisson Neponuceno de Araújo Filho, José Joatan Rodrigues Júnior, Cicero Inácio da Silva Filho, Jémison Mattos dos Santos, Eliana Midori Sussuchi, Alceu Pedrotti

Abstract Lignocellulosic biocomposites offer a renewable alternative to petroleum-derived materials, yet their photodegradation behavior under accelerated weathering remains insufficiently characterized from a reliability standpoint. This study evaluated the mechanical performance and degradation patterns of a laminar biotextile–biogrid biocomposite intended as a biodegradable geosynthetic analogue for short- to medium-term erosion-control and soil-protection applications. The material was assembled from a Typha do …

20.08.2026journal-article

JMIR Formative Research

Performance of Two AI Approaches in ASReview Compared With Manual Screening for Dementia Care Literature Screening: Comparative Analysis

Dirk Steijger, Stella Thissen, Sil Aarts, Hilde Verbeek, Marjolein E de Vugt, Hannah Christie

Abstract Background Literature reviews rely on rigorous title and abstract screening by researchers, which is time-consuming. AI-assisted literature screening tools have been proposed to improve efficiency by prioritizing titles and abstracts with the highest likelihood of meeting the inclusion criteria, thereby reducing the need to screen all records. Objective This study aims to evaluate the performance of two AI-assisted screening approaches in ASReview (version 1.3; Department of Methodology and Statistics, Utr …

20.08.2026journal-article

Philosophical Transactions of the Royal Society B: Biological Sciences

How people use the peat swamp forests of the central Congo Basin

Cassandra Dummett, Ovide Emba Botuli, Shona J. Jenkins, Eustache Amboulou, Joe F. Langley, Jonas Ngouhouo-Poufoun, Corneille E. N. Ewango, Suspense Ifo, Simon Lewis

Abstract The central Congo Basin peatlands span 167 600 km2 and are the world's largest tropical peatlands. Hundreds of thousands of people live in the vicinity of the peatlands, but studies of how people use the peatlands do not, to our knowledge, exist. This article investigates people's use of peat swamp forests in three study sites in the Democratic Republic of Congo and the Republic of the Congo. Using participatory methods, we interviewed 407 people and learned that 100% of households use the peat swamp fores …

1 Zitationen
20.08.2026journal-article

Information Technology & People

Workarounds as work practice? Analysis of tension-resolving workarounds in organizations

Jakia Sultana, Say Yen Teoh, Stan Karanasios

Purpose This study examines the post-adoption workaround behavior by organizations using blockchain in the food supply chain, focusing on how they manage tensions that arise with blockchain use. It addresses a gap in existing research, which has largely concentrated on initial adoption decisions rather than ongoing use and adjustment. Design/methodology/approach This study employs a qualitative case-study design, examining organizations from two supply chains through 23 semi-structured interviews. Iterative themati …

20.08.2026journal-article

Diagnostics

Comparative Predictive Performance of Upper Gastrointestinal Bleeding Risk Scores and the CALLY Index in Geriatric Patients

Muge Gul Gulecoglu Onem, Soner Onem

Background/Objectives: Elderly patients with acute upper gastrointestinal bleeding (UGIB) are a high-risk group with significant morbidity and mortality. Various risk scoring systems have been devised to predict clinical outcome in UGIB, but their effectiveness in geriatric patients is unclear. The purpose of the present study was to evaluate the predictive performance of established UGIB risk scores in older adults and to compare the predictive performance of the C-reactive protein–albumin–lymphocyte (CALLY) index …

20.08.2026journal-article

Journal of health research and technology

Effects of an Integrated Knowledge, Exercise, and Blood Pressure Self-Monitoring Program on Older Adults With Hypertension: A Quasi-Experimental Study

Puji Setya Rini

Background: Hypertension management among older adults requires not only pharmacological treatment but also adequate knowledge, regular physical activity, and blood-pressure self-monitoring. However, the short-term effectiveness of integrated self-management interventions on knowledge and blood-pressure outcomes remains uncertain. Objective: This study aimed to evaluate the effects of an integrated hypertension education, structured exercise, and blood-pressure self-monitoring program on hypertension knowledge and …

20.08.2026journal-article

Working with Older People

Who cares for the caregivers? Job satisfaction, performance and loyalty among home caregivers of people with Alzheimer’s disease in Tunisia

Rym Khanfir

Purpose This study aims to explore the mechanisms that link job satisfaction, sense of self-efficacy and job loyalty of carers caring for Alzheimer’s patients at home in Tunisia, a non-Western context almost absent from the existing literature. Design/methodology/approach Exploratory qualitative study based on 12 semi-structured individual interviews (55 min on average, in Tunisian Arabic dialect), analyzed by manual reflexive thematic analysis in six steps (Braun and Clarke, 2006). Manual independent double-coding …

20.08.2026journal-article

FEBS Letters

The impact of aging on the gut‐liver axis in health and disease

Konstancja Gałat, Natalia Rzepka, Aleksandra A Kołodziejczyk

Aging is a complex biological process characterized by gradual impairment of organ function and increased susceptibility to disease. Among the systems most affected, the gut and liver are particularly important because of their role in metabolism, detoxification, and immune regulation. These two organs are closely connected through the portal vein and bile ducts, enabling continuous, bidirectional communication that coordinates homeostasis. Understanding how gut–liver communication changes with age is therefore cri …

20.08.2026journal-article

SECURITY AND PRIVACY

Privacy‐Preserving Federated Audio‐Visual Saliency Analysis and Data Sharing Architecture for Rehabilitation of People With Disabilities

Ning Fang

ABSTRACT Privacy constraints on facial, movement, and voice data restrict centralized model training across rehabilitation institutions. This study presents a privacy‐preserving federated audio‐visual saliency architecture, termed PPFAV, for edge‐based rehabilitation assessment. A three‐stream encoder represents speech instructions, dynamic action sequences, and static visual cues, while a self‐supervised cross‐modal alignment objective links synchronized instructions and movement responses. Before aggregation, cli …

20.08.2026journal-article

Geriatrics

Navigating Adversity in Older Age: An Integrative Review of Contemporary Resilience Concepts and Measurement Challenges

Chonlakarn Songsri, Pras Ramluggun, Pimwalunn Aryuwat

Background/Objectives: Ageing populations face complex challenges, yet many older adults maintain well-being despite adversity. Understanding resilience offers critical direction for health promotion. This integrative review takes a conceptual and methodological approach to resilience in older adults, with clear implications for geriatric care. The review addresses: (1) how resilience is conceptualised and measured; (2) individual, social, and contextual factors linked to resilience; and (3) the effectiveness of in …

20.08.2026journal-article

Chinese Medical Journal

Aging-, obesity-, and diabetes-related sarcopenia: Pathogenesis and interventions

Shuang Han, Qianqian Xiong, Qingqian Wu, Chengyan Han, Yingjuan Zhang, Jiahuan Zou, Ruyi Guo, Yue Gao, Zhuo-Xian Meng

Abstract As global aging accelerates, sarcopenia has become an increasingly important public health concern. Although typically recognized as an age-related condition, sarcopenia can develop and progress more rapidly under certain pathological conditions, such as obesity and type 2 diabetes. With the ongoing advancement of related research, the mechanisms underlying sarcopenia are being progressively elucidated. Management strategies include both nonpharmacological and pharmacological interventions. Resistance exer …

20.08.2026journal-article

Nutrients

Systematic Hydration Rounds Versus a Socially Assistive Robot to Promote Fluid Intake in Institutionalized Older Adults: A Quasi-Experimental Study

Cristina Vallès-Carvajal, Laia Selva-Pareja, Olga Masot, Maria Falcón-Villaitodo, Carla Camí, Teresa Botigué

Background: Several strategies have been proposed to promote hydration among institutionalized older adults, including systematic hydration rounds and, more recently, the use of Socially Assistive Robots (SAR). However, their implementation in nursing homes remains limited. Objective: To compare changes in fluid intake over a one-month period among residents exposed to two hydration-promotion strategies and to identify baseline characteristics associated with fluid intake. Methods: A quasi-experimental study was co …

20.08.2026journal-article

Journal of Ageing and Longevity

Bridging the Digital Divide in Smart Home Health Technologies for Older Adults: A Scoping Review of Barriers, Design Considerations, and Policy Implications

Oishee Ghosh, Haixin Wang, Jeffrey Gajdacs, Ahmed Elsharnouby, Ian H. D. Phillips, Pasqualina Santaguida, Qiyin Fang, M. Jamal Deen

The global shift toward an aging population presents significant challenges for healthcare systems. This is compounded by rising disability rates, fragmented care models that struggle to meet complex needs, and a digital divide caused by the emergence of smart technologies. This work aims to evaluate how the digital divide affects the adoption, usability, and perceived benefits of smart home technologies designed to support activities of daily living and health monitoring. The influences of socioeconomic status and …

20.08.2026journal-article

Frontiers in Public Health

Unraveling the pathway from treatment burden to holistic health status in older adults with complex multimorbidity: the mediating roles of stress adaptation and depressive symptoms

Yajun Shi, Jie Su, Yujia Fu, Ying Zhang, Yu Sheng, Huafang Zhang, Jing Shao

Background Patients with complex multimorbidity are prone to fall into the cycle of “burden-management failure-deterioration” under the overspending of resources due to the complex management burden of cross-system chronic diseases superimposed on frequent visits and polypharmacy. Aim To investigate the relationship between treatment burden and holistic health status in older adults with complex multimorbidity, and to analyze the mediating effects of depressive symptoms and stress adaptation capacity on holistic he …

20.08.2026journal-article

Journal of The Electrochemical Society

Time and Temperature Dependent Aging Mechanisms in Commercial Lithium-Ion Cells with SiO x /Graphite Anodes

Jihed Ayari, Mintao Wan, Dominic Bresser, Thomas Waldmann

This work addresses the limited understanding of how changes in SiO x /graphite anodes and the N/P ratio induced by aging influence the temperature-dependent transition between degradation mechanisms. It provides insight into the potentially evolving risk of lithium plating and its implications for the safe and durable operation of batteries. Commercial 3.5 Ah Li-ion 18 650 cells with SiO x /graphite anodes (∼2.5 wt.% Si) and Ni-rich LiNi 1− x − y Mn x Co y O 2 cathodes were systematically aged in the temperature r …