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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
28.08.2026journal-article

Malignant tumours

Sebaceous carcinoma of the vulva: a clinical case and a literature review

V. V. Saevets, A. Yu. Shamanova, N. K. Kuzmin, L. V. Yarina

Background. Vulvar cancer (VC) is a rare malignancy in women, accounting for no more than 4 % of all cancers. Sebaceous histologic subtypes of VC are exceptionally uncommon. We summarize our own experience and that of other authors regarding presentation, diagnosis, and management. Objective. To present a clinical case of vulvar sebaceous carcinoma and synthesize the available literature to clarify the clinicopathologic features, diagnostics, treatment, and prognosis of this malignancy. Materials and Methods. We de …

28.08.2026journal-article

BMC Oral Health

Calcifying odontogenic cyst mimicking endodontic pathology: a case of unnecessary endodontic treatment of vital teeth

Hosam Zebda, Sarah Obeidat, Amr Abdelmoez, Ali Fahd

Abstract Background Calcifying Odontogenic Cyst (COC) is a rare developmental odontogenic lesion that may present as a periapical radiolucency, mimicking inflammatory pathology and posing a diagnostic challenge. Case presentation In this report, a 17-year-old female patient was referred to an oral surgery practice with a history of recurrent swelling and pain in the anterior mandible. Teeth 31, 41, and 42 (according to the FDI International two-digit system) had been endodontically treated by the referring dentist …

28.08.2026journal-article

Економіка та суспільство

DIGITAL MATURITY: EVIDENCE FROM A 24-COMPANY ASSESSMENT WITH THE RR-FRAMEWORK

Роман Резніков

The article presents a cross-industry empirical assessment of business resilience and digital maturity in twenty-four organizations using the RR-framework. The study addresses the need for reproducible diagnostics that connect maturity gaps with crisis exposure and prioritized action. The method combines a 424-item assessment across seventeen domains, confidence adjustment, crisis stress testing, fuzzy resilience posture, and analytic and Monte Carlo tail-risk estimation, followed by descriptive and correlation ana …

28.08.2026journal-article

Frontiers in Medicine

Hemoptysis risk in hospitalized patients with bronchiectasis: development and external validation of a clinical prediction model

Zhijing Gong, Yi Wang, Xinxiu Liu, Jian Lu, Zhigang Cai

Background Hemoptysis is a complication of bronchiectasis, but risk prediction in hospitalized patients remains insufficiently characterized. Existing bronchiectasis severity scores were developed to predict mortality, hospitalization, or exacerbations rather than hemoptysis. We aimed to develop and externally validate a model for in-hospital hemoptysis risk and interpret its predictors within prespecified clinical domains. Methods This retrospective two-center study included 320 hospitalized adults with bronchiect …

28.08.2026journal-article

PLOS Mental Health

Beyond the clinic: The role of the psychiatrist in practicing pragmatic solidarity

Anne Berhe, Abishek Bala, Tobi Okopie, Jennifer Agwagom, Manal Khan, Suzan J. Song

Psychiatrists are trained to evaluate biological, psychological, and social dimensions of illness simultaneously, yet the dominant frameworks governing psychiatric practice remain oriented toward individual symptom management rather than the structural conditions that produce these symptoms. This essay argues that psychiatrists working in global mental health contexts carry an ethical obligation that extends beyond diagnosis and treatment: to practice what Paul Farmer termed pragmatic solidarity, the practice of st …

28.08.2026journal-article

Sercapo Journal Scientific

La moda digital y los avatares virtuales: Un nuevo mundo para el diseño de modas

María Belén Chávez Dávalos, Andrea Sofía Sánchez López, Nancy Raquel Ramírez Bonilla, Carlos Luis Gusqui Guananga

El objetivo de este artículo fue analizar la contribución de una propuesta formativa basada en moda digital, avatares virtuales y realidad aumentada aplicada al desarrollo de destrezas de diseño de modas en participantes vinculados a procesos creativos, técnicos y proyectuales. La investigación se planteó como un estudio cuasi experimental, de enfoque correlacional descriptivo, con grupo de control y grupo experimental, integrado por 40 participantes entrenados en cuatro centros de formación. Se elaboró un test de …

28.08.2026journal-article

JAMA Network Open

Nursing Activities and Role Variation in Veterans Health Administration Primary Care

Chelsea McConnell, Elvira E. Jimenez, Charlene Pope, Rong Guo, Traci Solt, Laura Coyle, Jami Falk, Evelyn T. Chang

This quality improvement study surveyed Veterans Health Administration (VHA) nurses to better understand primary care nursing activities and their alignment with nurses’ training and scope of work.

28.08.2026journal-article

Brazilian Journal of Implantology and Health Sciences

Alterações Endócrinas Induzidas por Esteroides Anabolizantes em Atletas: Atualizações sobre Diagnóstico, Manejo e Prevenção

Cássia Ellen Silva Castro, Ana Laura Freitas Queiroz, Hugo Marques Weiller, Fernando Gabriel Bertolini, Gustavo Gabriel Géa, João Roberto José Silva, Cliza Alves Silva, Roger Barros Ciriaco Camargo, Matheus Henrique Gutierris Vieira, João Pedro Javarez Vasconcelos, Luiz Felipe Pereira Rocha, Maria Fernanda Monteiro Costa, Luiza Roderjan Malucelli, Marcos Vinícios Portela Bezerra

Introdução: O uso de esteroides anabolizantes androgênicos (EAA) em doses suprafisiológicas é uma prática associada à busca por aumento de massa muscular e desempenho esportivo. Apesar de seus efeitos anabólicos, essas substâncias podem interferir profundamente no funcionamento endócrino, cardiovascular, hepático e reprodutivo. A Sociedade Brasileira de Endocrinologia e Metabologia destaca que não existe dose considerada segura para utilização inadequada com finalidade estética ou de performance. Objetivo: Revisar …

28.08.2026journal-article

Biomedicines

Implementation of a Laboratory-Integrated Clinical Decision Support System for CKD Screening and Progression Detection in Primary Care

Jordi Tortosa-Carreres, Jonnathan Acevedo-Galvis, Mónica Piqueras, William Harold, Carmen Ramos, Jose Luis Górriz, Enrique Rodríguez-Borja, Francisco Brotons-Muntó, Eugenia Avelino-Hidalgo, Pablo Molina, Begoña Laíz-Marro

Background: CKD remains substantially underdiagnosed and inadequately monitored. Objectives: To evaluate whether a laboratory-integrated CDSS enables opportunistic CKD detection and longitudinal surveillance in Primary Care via automated KDIGO stratification and progression detection. Methods: We implemented a CDSS embedded within the laboratory information system at Hospital Universitari i Politècnic La Fe, a tertiary university hospital in València, Spain. A one-time baseline profile screened patients with diabet …

28.08.2026journal-article

Medicina

Prevalence of Anxiety and Depression and Their Association with Health-Related Quality of Life Among Oncology Patients in Iraq: A Cross-Sectional Study

Ahmed Lateef Abed Alkhaqani, Miklós Sugár, Ammar Mahmood Jaber, Ali Abbas Rahi Al-Murshedi, Dávid Sipos, Nóra Rozmann, Bence Raposa

Background and Objectives: Anxiety and depression are among the most common psychological symptoms in patients with cancer and are associated with morbidity and impaired health-related quality of life (HRQoL), independent of the cancer stage. This study aimed to determine the prevalence of clinically significant anxiety and depression among adult oncology patients in Iraq and quantify the independent contribution of these symptoms to HRQoL. Materials and Methods: A cross-sectional study was conducted between 1 Nove …

28.08.2026journal-article

International Journal of Information Technology & Decision Making

An integrated decision-making framework for prioritizing the barriers and applications in medical digital twins under hesitant fuzzy linguistic environment with stochastic probabilistic distribution

Yan Zhang, Qun Wu, Ligang Zhou, Yuhan Wangzhu, Muhammet Deveci, Dragan Pamucar

The rapid evolution of digital twins (DTs) technology is reshaping the medical service system. As medical DTs (MDTs) are themselves complex, existing decisionmaking framework often ignored decision-makers’ (DMs’) hesitant fuzzy preference information and subjective cognitive biases. This research develops an integrated decision-making framework for prioritizing the MDTs barriers and applications with the hesitant fuzzy linguistic term sets (HFLTSs) incorporating stochastic probabilistic information. Aligned with th …

28.08.2026journal-article

Personality and Mental Health

Individual Differences in Sleep Quality: Exploring the Impact of Temperament on Sleep Through Anxiety and Depression

Stefano Lasaponara, Angelica Scuderi, Elisa Pellegrini, Ludovica Annarumma, Valentina Piga, Sara Lo Presti, Maurizio Gorgoni

ABSTRACT According to the functional ensemble of temperament (FET) model, individual differences in temperament arise from the balance of neurotransmitter systems also crucial for regulating circadian rhythms and sleep, suggesting a strong neurobiological link between temperament and sleep behavior. The present cross‐sectional study examined whether FET‐defined temperamental traits predict interindividual variation in sleep measures. A total of 394 healthy adults completed the Structure of Temperament Questionnaire …

28.08.2026journal-article

International Journal of Public Health and Medical Research

Brain Network and Synaptic Plasticity Changes Associated with Electroconvulsive Therapy for Depression: A Multilevel Review

Yihan Jiang, Xinying Jiang, Yuting Huang, Xiaohui Yu

Electroconvulsive therapy (ECT) is an important treatment for severe, treatment-resistant, or high-risk depression, yet the relationship between its antidepressant effects, brain network changes, and cellular and molecular processes remains incompletely understood. Recent advances in multimodal magnetic resonance imaging (MRI), magnetic resonance spectroscopy (MRS), molecular biology, and animal electroconvulsive stimulation models have provided multilevel evidence for understanding the neurobiological mechanisms o …

28.08.2026journal-article

International Journal of Public Health and Medical Research

Study on the Mechanism of Tooth Tissue Repair Based on Stem Cell Regeneration Technology

Jintong Lv

This study focuses on the mechanism of tooth tissue repair using stem cell regeneration technology, an interdisciplinary frontier in regenerative medicine and tissue engineering. Dental-derived mesenchymal stem cells, including Dental Pulp Stem Cells (DPSCs), Stem Cells from Human Exfoliated Deciduous Teeth (SHEDs), and Periodontal Ligament Stem Cells (PDLSCs), possess excellent proliferation ability and multi-directional differentiation potential, which provide a promising approach for functional repair of damaged …

28.08.2026journal-article

Frontiers in Artificial Intelligence

Deep generative modeling for AI-guided inverse design of perovskite photovoltaic devices

Parvez Amin Khan, Muhammad Tipu Sultan, Md Mahamudul Islam, Md. Emran Hossain, Samiur Rahman

Introduction Perovskite solar cells (PSCs) have rapidly approached the performance ceiling of mature single-junction photovoltaics, yet further improvement is constrained by the high-dimensional, non-linear coupling between device parameters and power-conversion efficiency (PCE). This work presents an end-to-end AI-guided inverse-design framework that learns the conditional distribution of device parameters given target photovoltaic figures of merit. Methods The framework is trained and validated on 49,998 drift-di …

28.08.2026journal-article

Jurnal Abdimas Universitas Insan Pembangunan Indonesia

OPTIMALISASI PENJUALAN UMKM MELALUI PELATIHAN PEMANFAATAN ARTIFICIAL INTELLIGENCE (AI) UNTUK PEMBUATAN MEDIA PROMOSI DAN PRODUK DIGITAL

Nana Supiana, Nurasiah, Yayah Yulia, Bonar Napitupulu, Didi Sutardi, Samsul Makin, Joni Iskandar, Ferdi Kuswandi, Karnawi Kamar, Gusli Chidir, Adiyanto, Firdaus Putra, Hatoli Waruwu, Admiral, Azhari, Yusuf Sudiono, M. Rizky Wijaya, Akhmad Farhan, Yeremia Mendrofa, Adi Widodo

Pengabdian ini bertujuan meningkatkan kapasitas pelaku UMKM dalam memanfaatkan kecerdasan buatan atau Artificial Intelligence (AI) untuk pembuatan media promosi dan produk digital guna mendukung optimalisasi penjualan. Permasalahan utama mitra adalah keterbatasan kemampuan membuat konten promosi yang menarik, keterbatasan waktu dalam produksi materi pemasaran, dan belum optimalnya pemanfaatan teknologi digital. Kegiatan dilaksanakan melalui pelatihan interaktif, praktik langsung, dan pendampingan penggunaan AI untu …

28.08.2026journal-article

Journal of Clinical Medicine

Surgical Management of Hidradenitis Suppurativa Using Staged Carbon Dioxide Laser Marsupialization

Sydney R. Resnik, Alexander R. Gomez-Lara, Lauren Fernandez, Irena Pastar, Akhil Wadhera, Paul G. Hazen, Barry I. Resnik

Background: Hidradenitis suppurativa (HS) is a chronic disease marked by symptoms of pain, drainage, and odor. Persistent abscesses, nodules, and scarred tunnels can be resistant to pharmacologic management, with chronic lesions often requiring complex surgical intervention. Treatments include en bloc excision with primary closure, tissue flaps or skin grafts. Such procedures are associated with post-operative challenges, including pain, infection, contractures, and high recurrence rates. Methods: Herein we report …

28.08.2026journal-article

Salud Medicina e Innovación Journal

Fenotipado multimodal basado en inteligencia artificial para el síndrome de Ehlers-Danlos hipermóvil: manifestaciones gastroenterológicas, mucocutáneas, neuro-ORL y emergenciológicas

Melany Sofia Paredes Astudillo, Erika Alejandra Zúñiga San Lucas, Miguel Santiago Ulquiango Barrera, Cristian David Naranjo Ibarra, Bryan David Alvarado Guaman

Introduction: Hypermobile Ehlers-Danlos syndrome (hEDS) is a heterogeneous connective tissue disorder characterized by joint hypermobility, instability, chronic pain, and multisystem manifestations, lacking a definitive genetic biomarker, which complicates early diagnosis and phenotypic stratification (Hakim, 2024; Malfait et al., 2017). Objective: To synthesize the available evidence on the application of multimodal AI-based phenotyping to identify phenotypic subgroups of hEDS with gastroenterological, mucocutaneo …

28.08.2026journal-article

MENA Journal of Case Reports

Hereditary Angioedema with Varied Clinical Presentations: A Case Series

Hamna Hanif, Maha Ahmed, Sabiha Anis

IntroductionHereditary angioedema (HAE) is a rare, potentially life-threatening condition caused by deficiency or dysfunction of C1 esterase inhibitor (C1-INH). It is often misdiagnosed because it clinically resembles other causes of angioedema, such as allergic or acquired forms. Case Series presentationThis paper highlights two cases of adolescent boys with recurrent, non-pruritic angioedema, without associated urticaria. The first patient experienced mild facial edema without identifiable triggers, along with al …

28.08.2026journal-article

Journal of Mechanics in Medicine and Biology

A SMART HEALTH EVALUATION SYSTEM AND OPTIMIZATION MECHANISM FOR SPORTS ACTIONS INCORPORATING BigGAN

FAN ZHANG, TIANLI HAO, LONGYU HE

To meet the growing demand for sports motion recognition in training assistance, rehabilitation assessment, and intelligent monitoring, this study developed an auxiliary action-recognition evaluation framework incorporating a Big Generative Adversarial Network (BigGAN)-based data augmentation mechanism. An experimental subset was first constructed from representative sports actions in the Nanyang Technological University RGB[Formula: see text]D120 (NTU RGB [Formula: see text] D120) dataset, including running, jumpi …

28.08.2026journal-article

Frontiers in Psychology

Associations of anxiety and depression with sexual health among infertility patients: a systematic review

Changmin Niu, Yuxin Gao, Qiulian Xu, Fan Yang, Shikun Ma, Nuo Shen, Wenxuan Zhu, Yidi Kong, Lu Chen, Guiqin Wang

Purpose This study aims to systematically review the associations between anxiety, depression, and the sexual health of patients with infertility, providing a theoretical foundation for reproductive health professionals to develop targeted interventions. Methods A comprehensive literature search was conducted in four English databases (Cochrane Library, EMBASE, Web of Science, and PubMed) and two Chinese databases (CNKI and Wan Fang) from inception to December 31, 2025. Studies were selected following the Preferred …

28.08.2026journal-article

Cancers

Clinical Outcomes and Prognostic Factors Following Routine CT-Based Image-Guided Adaptive Brachytherapy for Cervical Cancer: A Retrospective Cohort Study

Pooriwat Muangwong, Ekkasit Tharavichitkul, Somvilai Chakrabandhu, Pitchayaponne Klunklin, Wimrak Onchan, Bongkot Jia-Mahasap, Piyapasara Toapichattrakul, Wannapha Nobnop, Anirut Watcharawipha, Razvan M. Galalae, Imjai Chitapanarux

Background/Objectives: Magnetic resonance imaging (MRI)-based image-guided adaptive brachytherapy (IGABT) is the preferred standard for cervical cancer, but access remains limited in many settings. Computed tomography (CT)-based IGABT provides a practical alternative. We evaluated clinical outcomes and prognostic factors following its routine implementation. Methods: This retrospective cohort study included patients with International Federation of Gynecology and Obstetrics (FIGO) 2018 stage I–IVA cervical carcinom …

28.08.2026journal-article

PLOS One

Electronic health record evidence suggests undercoding, underrecognition, and low antifibrotic use in progressive pulmonary fibrosis

Bradley A. Sheffield, Brian J. Cassel, Apostolos Perelas, Patricia Sime, Peter Jackson

Background Progressive pulmonary fibrosis (PPF) is a heterogeneous group of non-IPF ILDs characterized by fibrotic progression and poor prognosis. Antifibrotic therapies slow disease progression, yet widely variable real-world prevalence estimates suggest that PPF may be undercoded and potentially underdiagnosed. In preliminary TriNetX analyses using ICD-10 code J84.170, PPF prevalence was markedly lower than previous estimates. To explore a potentially undiagnosed and/or uncoded PPF cohort, we adapted a published …

28.08.2026journal-article

Journal of Smart Algorithms and Applications (JSAA)

Artificial Intelligence for Automated Semen Analysis from Microscopy to Clinical Translation

Shimaa B. bahy, Mostafa Ahmed, Ahmed A. Elngar

Male-factor infertility is commonly evaluated using semen analysis; however, manual assessment of sperm concentration, motility, and morphology remains susceptible to observer variability and laboratory heterogeneity. This review synthesizes artificial intelligence methods for automated semen analysis, covering sperm detection, segmentation, morphology classification, motility assessment, tracking, and hybrid computational pipelines. A literature search was conducted across PubMed/MEDLINE, IEEE Xplore, Scopus, Web …