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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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Aktuelle Forschung nach Fachgebiet

24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
20.08.2026journal-article

BMC Sports Science, Medicine and Rehabilitation

Trainability of repetitions-in-reserve estimation in younger and older adults: a parallel-group repeated-measures study

Tim Wiedenmann, Daniel Kunellis, Ludwig Rappelt, Steffen Held, Pamela Wicker, Lars Donath

Abstract Background Effort-based resistance training (RT) approaches, such as repetitions (reps) in reserve (RIR), aim to enhance RT individualization, which is of particular relevance for older adults. However, evidence regarding the accuracy of RIR estimation and its trainability in this population remains limited. This study aimed to (I) compare RIR estimation accuracy between younger and older adults, and (II) determine whether six training sessions improve estimation accuracy in both groups. Methods The study …

20.08.2026journal-article

Research on Aging

From ‘a Normal Part of Aging’ to ‘an Explanation for my Symptoms’: Insights From Patient-Care Partner Dyad Interviews About the Cognitive Impairment Diagnosis Process in Primary Care

Maren S. G. Henderson, Meghan M. JaKa, Laura J. Zibley, Bethany K. Crouse, Ann Werner, Patrick J. O’Connor, Heidi L. Ekstrom, Soo Borson, Rebecca C. Rossom, Leah R. Hanson

Despite increasing pressure on primary care clinicians to provide accurate and timely assessment and diagnosis of cognitive impairment (CI), many remain unprepared. To inform improvement, we conducted interviews with 20 dyads of recently diagnosed patients and their care partners (spouses or adult children) to better understand experiences with CI assessment and diagnosis in primary care. Dyads reported wide variation in how primary care responded to their initial cognitive concerns, ranging from compassionate prio …

20.08.2026journal-article

Eurosurveillance

Antibiotic treatment and antimicrobial resistance in urinary tract infections among the older population in Denmark, 1999 to 2023

Majda Attauabi, Diana Schultz Christensen, Laura Marie Christensen, Jonas Kähler, Ute Wolff Sönksen, Anne Byriel Walls

BACKGROUND Antimicrobial resistance is highly correlated with inappropriate antimicrobial use. Urinary tract infections (UTIs) are the main infections treated with antibiotics in the population ≥ 70 years. AIM We aimed to investigate antibiotic prescribing patterns for UTIs treatment among older people in Denmark and resistance trends to assess impact of antibiotic stewardship interventions and quality improvement strategies. METHODS This national register-based surveillance study included people ≥ 70 years in Dani …

20.08.2026journal-article

O Mundo da Saúde

Atenção domiciliar às pessoas idosas: caracterização do cuidado na Atenção Primária à Saúde

Thamiris Grizante Aurelio, Luís Eduardo Genaro, Aylton Valsecki Júnior, Fernanda Lopez Rosell

O Brasil enfrenta uma rápida transição demográfica, com aumento da população idosa e expectativa de vida. Juntamente a isso ocorre uma transição nutricional e epidemiológica que se correlacionam a partir da má-alimentação e da prevalência de doenças crônicas, especialmente nas pessoas idosas. Essa transição que apresenta o envelhecimento da população ressalta a necessidade de cuidados primários dessas pessoas. Neste contexto, a atenção domiciliar (AD) é definida como um conjunto de ações e serviços destinados à pro …

20.08.2026journal-article

African Journal of History and Archaeology

A Critical Review of Shokpeka’s Account of the Traditions of Origin of the Indigenous People of Etsako

Michael Eshioke Okemi

This study critically examines Shokpeka’s account of the tradition of origin of Etsako and Okpella people and its variant, and Masagbo’s traditions of origin of Okpekpe people to ascertain who the original inhabitants of Etsako land were before the arrival of Benin migrants. The question has been, who were the original inhabitants of Etsako land before the arrival of Benin migrants? How do we identify them? Was there a change in the language, dress, culture, tradition etc. of the people when the migrants arrived? C …

20.08.2026journal-article

Focus Localis

Osallisuus ja siihen yhteydessä olevat tekijät yksin asuvien ikääntyneiden kuvauksissa

Aino Asunmaa, Hanna Ristolainen, Jenni Kulmala, Elisa Tiilikainen

Strengthening social inclusion of older people has been defined as an important social policy goal, but little is known about older people's own views and experiences of inclusion. The study examines how social inclusion, and its conditions are expressed by older people living at home and which factors are related to the experience of inclusion. Data were derived from group discussions (n=4) including a total of 19 older people aged 70 and over living alone. The results show that inclusion is a multifaceted experie …

20.08.2026journal-article

Scientific Reports

Ulnar styloid fractures and early clinical outcomes in older patients with conservatively treated distal radius fractures: a TriNetX database-based retrospective cohort study

Huu Dat Nguyen, Thanh Tan Nguyen, Phuoc Giau Dang, Yi-Jie Kuo, Lien-Chen Wu, Yu-Pin Chen

Abstract While ulnar styloid fractures (USF) are common concomitants of distal radius fractures (DRF), their impact on recovery in conservatively treated geriatric patients remains controversial. This study evaluated whether concomitant USF was associated with early healthcare-recorded outcomes. Using the TriNetX US Collaborative Network database (2005–2023), we identified patients ≥ 65 years with conservatively managed DRF. A total of 18,032 patients with distal radius fracture and concomitant ulnar styloid fractu …

20.08.2026journal-article

Journal of Gastroenterology and Hepatology

Gaps in the Cascade of Care Contribute to Poor Liver Cancer Outcomes Among People Living With Hepatitis B: A Multicenter Observational Cohort Study

Dina Moussa, Joan Ericka Flores, Michael Macisaac, Jack Wallace, Joseph Doyle, Marno Ryan, Thai Hong, Brett Knowles, Adrian Fox, Ashu Jhamb, Tom Sutherland, Stuart Roberts, William Kemp, Ammar Majeed, Marie Sinclair, Rohit Sawhney, Stephen Bloom, Amanda Nicoll, Zina Valaydon, Gauri Mishra, Sid Sood, Diana Lewis, A. Thompson, J. Howell

ABSTRACT Background Chronic hepatitis B virus (HBV) remains a major cause of hepatocellular carcinoma (HCC) in Australia, despite the availability of effective, subsidized antiviral therapy. We aimed to describe the clinical characteristics, HBV care cascade, and outcomes among people with HBV‐related HCC in Victoria, Australia. Methods We conducted a multicenter cohort study of all incident HCC cases across eight tertiary health networks in Victoria, Australia. Cases were identified retrospectively (January 1, 201 …

20.08.2026journal-article

Journal of Internal Medicine

Habitual fasting duration and accelerated multimorbidity in older adults

Luis Kalmbach, David Abbad‐Gomez, Giorgi Beridze, Fernando Rodríguez‐Artalejo, Davide Liborio Vetrano, Amaia Calderón‐Larrañaga, Adrián Carballo‐Casla

Abstract Background Prolonged fasting has been linked to metabolic benefits in younger adults, but its effects on chronic diseases in older populations remain unclear. Objective To examine the association between habitual fasting duration and 15‐year chronic disease accumulation in older adults, overall, within organ systems, and between age groups. Methods Data were drawn from the Swedish National study on Aging and Care in Kungsholmen, a longitudinal population‐based cohort of 2981 predominantly community‐dwellin …

1 Zitationen
20.08.2026journal-article

international journal of advanced research in computer science

INVESTIGATING LINK-STATE ADVERTISEMENT AGING IN OSPF FOR NETWORK FAULT DIAGNOSIS

Amit Sharma

Open Shortest Path First (OSPF) utilizes Link-State Advertisements (LSAs) to keep precise information about network topology. This research empirically examines the aging behavior of LSAs and their significance in diagnosing faults within OSPF networks. In a simulated OSPF environment, different fault scenarios including link failures, adjacency instability, and inconsistencies within the database are introduced and assessed based on LSA age variations among various LSA types. The findings indicate that unusual agi …

20.08.2026journal-article

Journal of General Internal Medicine

Bridging Social Determinants of Health and Multidimensional Frailty Among Older Adults: A Domain-Specific Latent Class and Network Analysis

Ying Gao, Denise Shuk Ting Cheung, Pui Hing Chau

Abstract Background Social determinants of health (SDoH) are increasingly recognized as key contributors to frailty, yet their multidimensional associations remain underexplored. This study examined how multiple SDoH domains and specific variables relate to distinct frailty domains among Chinese community-dwelling older adults. Methods We analyzed 10,654 adults aged ≥ 60 years in the 2020 China Health and Retirement Longitudinal Study. Five SDoH domains, defined by the Healthy People 2030 framework, were assessed: …

20.08.2026journal-article

Journal of the American Heart Association

Amyloid‐Related Imaging Abnormalities Summit Special Proceedings: Cardiovascular and Stroke Considerations for β‐Amyloid Immunotherapy in Alzheimer Disease

Steven M. Greenberg, Costantino Iadecola, Sherry H.‐Y. Chou, Petrice M. Cogswell, Mitchell S. V. Elkind, William J. Hicks, Caitlin Le, Deborah A. Levine, Richard Lipton, Lauren Massimo, Stephanie M. Mohl, Sudha Seshadri, Heather M. Snyder, Kristine Yaffe, Kori S. Zachrison, Robert Adams, Marc Agronin, Alireza Atri, Mary Ann Bauman, James L. Bernat, Alessandro Biffi, Sonja Blum, Thierry Bussiere, Tara C. Carlisle, Maria C. Carrillo, Gloria Chiang, Kenrick Cato, Alexander Chaitoff, Suzanne Bakken, Matthew W. Schelke, Salvador Cruz‐Flores, Janice Y. Chyou, Colin Derdeyn, Amar Dhand, David A. Evans, Cameron Gettel, Larry B. Goldstein, Joshua Grill, Makoto Ishii, Ambar Kulshrestha

Background New antiamyloid therapies (AAT) for treating patients with early Alzheimer disease (AD) have become available in the past 3 years. Although AAT can be beneficial in slowing progression of AD, they also come with potentially serious side effects, particularly for patients requiring anticoagulation or thrombolysis for cardiovascular conditions. Given that most patients with AD are older and likely to have cardiovascular risk factors, there is urgent need for additional guidance for clinicians about potenti …

20.08.2026journal-article

Annals of Clinical Endocrinology and Metabolism

Risk Factors and Their Impact on Diabetes Mellitus in Elderly People

Bilić-Komarica Edina

Diabetes mellitus is a metabolic disorder characterized by chronic hyperglycemia and disrupted carbohydrate, fat, and protein metabolism, representing a growing health issue in Bosnia and Herzegovina, particularly among the elderly. This study evaluated the accumulation and distribution of identified risk factors among 108 elderly patients with type 2 diabetes (54 females and 54 males) treated at the Clinical Center University of Sarajevo. Evaluated risk factors included age, sex, hyperlipidemia, adiposity, family …

20.08.2026journal-article

Nuclear Medicine Communications

Whole body fluorine-18 fluorodeoxyglucose parametric PET/computed tomography in people with long coronavirus disease: the ERASE-LC trial protocol

Hairil Rashmizal Abdul Razak, W. David Strain, Patrick Rogers, Mark A. Faghy, Lindsay Skipper, Sascha H. Kranen, Kinan Mokbel, Tom Bewick, Ruth Ashton, Kayle-Anne Sands, Helen Neilens, Amber Lord, Helen Hambly, Jade Chynoweth, Victoria Allgar, Michelle Scott-Cleasby, Jackie Hoare, Karen M. Knapp

The ERASE-LC feasibility trial will evaluate the feasibility of using remdesivir for the treatment of long coronavirus disease (COVID) with a wide range of outcome measures. This paper focuses on the nested parametric PET/computed tomography study and outlines the novel protocol utilized. The PET/computed tomography scans will be performed at one of the sites in 20 participants with an overall recruitment target of 72 participants across both centers. The PET/computed tomography scans will be performed at day 11 fo …

20.08.2026journal-article

Tạp chí Y học Dự phòng

Tình hình và yếu tố liên quan đến tiêm ngừa vắc xin của người cao tuổi tại phường Ô Môn, thành phố Cần Thơ năm 2025

Minh Hữu Lê, Hoàng Hiếu Lê, Anh Thư Huỳnh, Thị Mỹ Như Trịnh, Hoàng Hải Lê, Uyên Nhi Đoàn Võ

Tiêm ngừa vắc xin đóng vai trò quan trọng cho người cao tuổi. Trên thế giới và tại Việt Nam đều có khuyếnnghị tiêm ngừa vắc xin hàng năm cho tất cả những người từ 60 tuổi trở lên. Mục tiêu nghiên cứu nhằmxác định tỷ lệ tiêm ngừa và mô tả một số yếu tố liên quan đến tiêm ngừa vắc xin của người từ 60 tuổi trởlên tại phường Ô Môn, Thành phố Cần Thơ năm 2025. Nghiên cứu cắt ngang mô tả có phân tích trên 420người từ 60 tuổi trở lên tại địa bàn nghiên cứu. Các thông tin thu thập: đặc điểm dân số - xã hội, tình hìnhtiêm c …

20.08.2026journal-article

Applied Cognitive Psychology

Do Momentary Stress and Busyness Predict Naturalistic Prospective Memory Differently in Younger and Older Adults?

Nicola Ballhausen, Maximilian Haas

ABSTRACT Everyday prospective memory (PM), such as remembering medication intake or appointments, is crucial for independence and quality of life, especially in older age. However, little is known about how momentary stress and busyness as contextual factors differentially affect naturalistic PM. Forty younger (18–27 years) and 40 older adults (60–84 years) completed a 14‐day ambulatory assessment of various naturalistic PM tasks, alongside time‐contingent reports of stress and busyness. Multilevel structural equat …

20.08.2026journal-article

Frontiers in Aging Neuroscience

Layered classification in Parkinson’s disease: a content analysis of clinical, prodromal, and biological criteria evolution

Aishanjiang Yusufujiang, Shan Zeng, Hongyan Li

Background Parkinson’s disease (PD) is no longer described through a single diagnostic vocabulary. Clinical criteria, prodromal probability models, and biological research classifications now operate in parallel after the 2024 NSD-ISS and SynNeurGe proposals. Objective To clarify how major PD criteria and research frameworks have justified diagnostic change and redistributed the roles of clinical signs, biomarkers, genetics, and prodromal markers. Methods We conducted a targeted document-based qualitative content a …

20.08.2026journal-article

European Geriatric Medicine

Integrated rehabilitation and ambulatory recovery in older adults with hip fracture according to muscle strength and sarcopenia status: a secondary analysis of a randomized controlled trial

Seung-Kyu Lim, Jae-Young Lim

Abstract Purpose Sarcopenia and impaired muscle strength are common in older adults with hip fractures and are strongly associated with poor functional recovery. Although integrated multidisciplinary rehabilitation improves outcomes after hip fracture, whether its benefits differ according to baseline muscle strength or sarcopenia severity remains unclear. This study aimed to examine whether the functional benefits of Fragility Fracture Integrated Rehabilitation Management (FIRM) vary according to sarcopenia status …

20.08.2026journal-article

eLife

Multiple molecular pathways to longevity with opposing gene expression programs defining distinct aging strategies in Caenorhabditis elegans

Zenith D Rudich, Jiaxi Guan, Aura A Tamez Gonzalez, Grant F Booth, Sonja K Soo, Ulrich Anglas, Meeta Mistry, Megan M Senchuk, Jeremy M Van Raamsdonk

While aging is the greatest risk factor for the development of neurodegenerative disease, the role of aging in these diseases is poorly understood. Our previous work has shown that targeting aging pathways can be neuroprotective in animal models of neurodegenerative disease. Based on these findings, we believe that by gaining insight into the aging process that knowledge can be applied to identify novel therapeutic targets for neurodegenerative disease. To advance our understanding of aging, we used a genomics appr …

20.08.2026journal-article

npj Aging

Sex differences in aging acceleration: higher susceptibility in women, greater preventability in men

Ziye Ren, Shuiyue Quan, Fangyu Li, Longfei Jia

Abstract Aging acceleration contributes to heterogeneity of chronic disease risk and mortality; however, the sex differences of its risk factors and population attributable fractions (PAFs) remain poorly characterized. We conducted an exposure-wide association analysis (ExWAS) among 236,099 UK Biobank participants and examined sex differences in exposure factors of aging acceleration and corresponding PAFs. Our results indicated that environmental exposures, lifestyles, early-life factors, psychosocial factors, and …

20.08.2026journal-article

Frontiers in Psychiatry

Machine learning-based identification of anxiety symptoms in Chinese community-dwelling older adults: a comparative study of six algorithms with SHAP analysis and nomogram development

Peiyue Li, Chunxiao Yan, Jianbo Li, Qimi Zheng, Huiqi Zhang

Background Anxiety disorders are common among older adults but remain underrecognized in community settings, particularly in China where mental health resources are scarce. This study aimed to develop and compare multiple machine learning models for identifying anxiety symptoms in Chinese community-dwelling older adults and to construct a practical clinical tool. Methods A cross-sectional study included 5,331 community-dwelling older adults (aged ≥65 years) from Shenzhen, China. Anxiety symptoms were assessed using …

20.08.2026journal-article

Journal of Leukocyte Biology

Circulating Platelet-Natural Killer Cell Complexes are Elevated in People Living with HIV on Antiretroviral Therapy

Brita Ostermeier, Amber Douglass, Tomas Raul Wiche Salinas, Sanchita Pandey, Cheryl Clarkson-Paredes, Gregory M Cresswell, Anastas Propratiloff, Marc Siegel, Conrad Russell Y Cruz, Mirko Paiardini, Sanjay B Maggirwar

Abstract Natural killer (NK) cells stand as a critical pillar in the innate immune defense against viral infections, particularly human immunodeficiency virus (HIV). However, during HIV infection, NK cells demonstrate profound dysfunction, undermining effective immune control and accelerating disease progression along with viral persistence. Understanding the mechanisms driving NK cell dysfunction is essential for the development of innovative therapeutic strategies. This study reveals a significant increase in cir …

20.08.2026journal-article

Frontiers in Public Health

Effects of qigong and resistance exercise on improving balance and cognitive ability of community-dwelling older adults

Wen Fu, Li Zhang, Yu Liao, Qi Zheng, Xiaolei Peng, Jiayu Zou, Tingjin Duan, Xiaochun Chen

Background To address the challenges posed by an aging society and reduce the incidence of falls and cognitive decline, there is a need for scientifically validated training methods that enhance both balance and cognitive function in older adults. Objective To evaluate and compare the effects of Baduanjin and Resistance Band training on improving balance and cognitive function in community-dwelling older adults. Methods A total of 93 community-dwelling older adults (mean age: 64.86 ± 3.13 years) were assigned accor …

20.08.2026journal-article

Frontiers in Public Health

Effects of Tai Chi-based combined interventions on muscle function, muscle mass, and physical performance in older adults with sarcopenia, frailty, or risk of functional decline: a systematic review and meta-analysis

Xudong Jin, Enliang Hu, Caiduo Shi

Background and objective Sarcopenia and frailty involve declines in muscle strength, muscle mass, and physical performance, and single Tai Chi may be insufficient to cover all functional needs. Tai Chi-based combined interventions have emerged, but their overall effects remain unclear. This study evaluated their effects in older adults with sarcopenia, frailty, or risk of functional decline. Methods We systematically searched PubMed, Embase, CENTRAL, Web of Science, Scopus, CINAHL, ClinicalTrials.gov , CNKI, Wanfan …