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Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
20.08.2026journal-article

Zoo Biology

The Responsibility of Zoos to Advance the Rights and Interests of Indigenous People

Jack Pascoe, Sally Sherwen

ABSTRACT The Earth is in its 6th mass extinction event, in 2022, in response to this crisis, 196 countries adopted the Kunming–Montreal Global Biodiversity Framework (GBF), a legally binding international agreement that aims to halt and reverse the trajectory of biodiversity loss by 2030. It is clear that Zoos have a role to play in this conservation effort; however, there has been less guidance for zoo and regarding how they can support the rights of Indigenous Peoples within this movement. In this paper, we explo …

20.08.2026journal-article

AGING MEDICINE

Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities

Xiaoming Wang, Cuntai Zhang

ABSTRACT Dysregulation of the renin‐angiotensin‐aldosterone system (RAAS) constitutes a pivotal factor in the onset and progression of various geriatric diseases, including cardiovascular diseases, diabetes, and chronic kidney disease (CKD), all closely linked to adverse cardiorenal outcomes in older patients. Excessive activation of the mineralocorticoid receptor (MR) drives inflammation, fibrosis, and oxidative stress across tissues and organs, representing a fundamental mechanism underlying systemic metabolic di …

20.08.2026journal-article

BMC Urology

Preoperative frailty and multidimensional concurrent correlates among older adults scheduled for radical cystectomy: a social ecological model-informed cross-sectional study

Yanhong Yan, Lina Wang, Yuehong Zhou, Xuejing Wang, Qiaoling Jiang, Ting Lu, Haiyan Ma, Jian Qian

Abstract Background Frailty is common in older adults considered for radical cystectomy (RC), but the nutritional, muscular, functional, psychological, behavioral, and social features that accompany frailty before surgery remain incompletely characterized. Using the Social Ecological Model as an organizational framework, we estimated frailty prevalence and examined concurrent correlates among older adults scheduled for RC. Methods This single-center cross-sectional study consecutively screened 151 adults aged 65 ye …

20.08.2026journal-article

BMC Infectious Diseases

People living with HIV and proportion diagnosed in Aotearoa New Zealand: first published national estimates from two modelling approaches

Julia Scott, Andrew Anglemyer, Susan McAllister, Jason J. Ong, Peter Saxton

Abstract Background Aotearoa New Zealand (NZ) is a country of low HIV incidence and prevalence where men who have sex with men (MSM) are most affected, and indigenous Māori inequitably affected by late diagnosis. NZ aims for 95% of people living with HIV (PLWH) diagnosed. We estimated PLWH and proportion (%) diagnosed in 2024 using two mathematical models; the first estimate by local researchers. Methods We used the European Centre for Disease Prevention and Control (ECDC) HIV Modelling tool and Spectrum Case Surve …

20.08.2026journal-article

Addiction

Prescribed alternative stimulants among people who use unregulated stimulants: Examining the association between maximum dose reached and medication discontinuation in the first 3 years of implementation in British Columbia, Canada

Bin Zhao, Kevin Hu, Roshni Desai, Shania Au, Kali‐olt Sedgemore, Vitor Tardelli, Addie Carter, Paxton Bach, Christian Schutz, Amanda Slaunwhite, Alexis Crabtree, Heather Palis

Abstract Background and aims In 2020, British Columbia (BC), Canada, introduced ‘Prescribed Alternatives’ (PA) as an approach to offering regulated substances to people accessing the unregulated supply. This study aimed to estimate and compare prescribing characteristics of dextroamphetamine and methylphenidate stimulant PAs in BC, to estimate medication discontinuation probabilities for each PA type by episode order, and to estimate the hazard ratio for medication discontinuation comparing episodes that reached a …

20.08.2026journal-article

Journal of Proteome Research

Integrated Hepatic Lipidome Analysis in Aging Mice

Punyatoya Panda, Christina R. Ferreira, Allison J. Schaser, Uma K. Aryal

Abstract The liver is a metabolically active organ vital for carbohydrate, protein, and lipid metabolism as well as detoxification of harmful substances. Here, we integrated multiple reaction monitoring (MRM) profiling, untargeted lipidomics, and desorption electrospray ionization-mass spectrometry imaging (DESI-MSI) to identify age-associated changes in lipid profiles in the liver of adult mice across three age groups: adult (3–4 months), midaged (10 months), and old (19–21 months). Comparative lipidomic analysis …

20.08.2026journal-article

Arthritis Care & Research

Factors Associated With Fibromyalgia Diagnosis Among People Meeting Criteria: Results From UK Biobank

Sung‐A Kim, Gary J. Macfarlane, Marcus J. Beasley

Objective The diagnosis of fibromyalgia (FM) is challenging due to the absence of definitive biomarkers, numerous overlapping comorbidities, and its reliance on patient‐reported symptoms. Discrepancies between diagnostic criteria and clinical practice imply the possibility of diagnostic biases, complicating timely and accurate identification. This study aimed to identify factors associated with receiving an FM diagnosis among individuals who met 2016 criteria and explore potential barriers to diagnosis. Methods Usi …

20.08.2026journal-article

Frontiers in Public Health

Construction strategies and implementation pathways of resilience governance system for care risks in older adult care institutions from a social-ecological perspective

Chunyan Li, Yang Xie, Weiping Liu

Against the backdrop of population ageing, the governance of care risks in older adult care institutions has become a global challenge. This paper aims to construct a resilience governance system for care risks in older adult care institutions based on social-ecological systems theory, exploring its construction strategies and implementation pathways. The article first reviews the development trajectory of resilience governance theory in social sciences, then introduces social-ecological systems theory into the res …

20.08.2026journal-article

Archives of Medical Science

The unequal burden of interstitial lung disease mortality in older US adults: a 22-year analysis and projections to 2030

Tong Feng, Pengcheng Zheng, Yue Cao, Ding Han, Ran Duan

Introduction Interstitial lung disease (ILD) comprises a heterogeneous group of disorders characterized by progressive lung fibrosis, respiratory failure, and substantial mortality, particularly among older adults. While prior studies have described historical ILD mortality trends, comprehensive analyses incorporating future projections, detailed geographic disparities, and socioeconomic variation remain limited. Material and methods We analyzed CDC WONDER underlying-cause-of-death data for US adults aged ≥ 65 year …

20.08.2026journal-article

Aging Cell

Aged Mitochondrial DNA Is Associated With Aberrant Acute Exercise‐Induced Redox Responses in Human Skeletal Muscle

Bradley A. Ruple, Nicholas A. Carlini, Jason S. Kofoed, Helya Rostamkhani, Brady E. Hanson, Jesse C. Craig, Shelby C. Osburn, Allison M. Manuel, Paul A. Stewart, Jonathan Wanagat, Ryan M. Broxterman, Joel D. Trinity

ABSTRACT Redox imbalances and mitochondrial dysfunction are key contributors to age‐related declines in skeletal muscle and may contribute to impaired exercise responsiveness. Here, we investigated the influence of aging on skeletal muscle redox at rest and in response to acute exercise, examining how mitochondrial quality and quantity relate to skeletal muscle redox status. Skeletal muscle biopsies were obtained from 12 young (22 ± 4 years) and 10 older adults (66 ± 7 years) before and immediately after 60‐min of …

20.08.2026journal-article

Frontiers in Nutrition

Luteolin promotes healthy aging in adult females but shortens lifespan after embryonic exposure in Drosophila melanogaster

Quanyong Wu, Boya Ouyang, Hui Cao, Min Zhang, Mohamed A. Farag, Thomas Efferth, Jesus Simal-Gandara, Jianbo Xiao

Introduction Luteolin is a dietary flavonoid widely distributed in fruits, vegetables, and medicinal plants and is recognized for its antioxidant and health-promoting properties. However, its effects on physiological aging and the influence of developmental stage and biological sex remain poorly understood. Methods In this study, Drosophila melanogaster was exposed to luteolin during either adulthood or embryonic development and evaluated for lifespan, healthspan, metabolic regulation, and aging-related molecular c …

20.08.2026journal-article

Revista Ibero-Americana de Humanidades, Ciências e Educação

AVANÇOS E DESAFIOS NA INCLUSÃO DE PESSOAS COM DEFICIÊNCIA EM ESCOLAS DO CAMPO NO DISTRITO DE SÃO GONÇALO, SOUSA-PB

Luzenira Carneiro Lacerda, Helmara Giccelli Formiga Wanderley Junqueira, Paulo Abrantes de Oliveira, Sthelio Braga da Fonseca, Girlan Guedes dos Santos, Michael Douglas Sousa Leite

A inclusão escolar de estudantes com deficiência em contextos rurais constitui um desafio que envolve condições pedagógicas, estruturais e sociais específicas. Nesse contexto, esse estudo teve como objetivo analisar a percepção dos responsáveis legais dos estudantes com deficiência acerca do processo de inclusão escolar nas escolas rurais do Distrito de São Gonçalo, em Sousa (PB), considerando acesso, infraestrutura, recursos de apoio, barreiras e participação familiar. Trata-se de estudo de caso, exploratório e de …

20.08.2026journal-article

Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz

Walkability im Alter – Umweltfaktoren der Wohnumgebung und funktionssensitive Messung im urbanen Raum

Daniela Koller, Eva Grill, Ralf Strobl

Zusammenfassung Walkability beschreibt die Gehfreundlichkeit einer Nachbarschaft und ist ein zentrales Konzept zur Förderung von Mobilität, körperlicher Aktivität und sozialer Teilhabe im Alter. Bestehende Ansätze bilden die spezifischen Bedürfnisse älterer Menschen bislang nur unzureichend ab, insbesondere bei funktionellen Einschränkungen. Der Beitrag zeigt, wie Walkability im höheren Lebensalter konzeptionell weiterentwickelt, funktionssensitiv erfasst und in einem urbanen Kontext empirisch untersucht werden kan …

20.08.2026journal-article

Scandinavian Journal of Public Health

Future trends in dementia incidence and mortality: projecting the burden of dementia on long-term care in Finland by 2040

Maria Guzman-Castillo, Kaarina Korhonen, Michael Murphy, Pekka Martikainen

Aims: We projected the future number of individuals with dementia and long-term care (LTC) residents in Finland by education level through 2040. We also examined the impact of different future scenarios regarding declining dementia and LTC trends, as well as the effect of past educational expansion on the future prevalence of dementia and LTC. Methods: A multistate model tracks the population aged 65 years and over through states characterised by the presence of dementia, LTC residence, or death. We calculated age, …

20.08.2026journal-article

Aging Cell

Molecular Mechanisms of Age‐Related Taste Dysfunction Deciphered by Spatiotemporal Transcriptomics

Wandong Zhao, Xudong Cha, Yingqi Xie, Enhao Wang, Wenlu Xing, Zengyi Xu, Langchao Liang, Changhai Xiong, Morong Zhou, Penghui Fu, Zhe Wang, Xin Liu, Yiqun Yu, Huanhai Liu, Hanbo Li, Wenwen Ren

ABSTRACT Age‐related taste dysfunction impairs nutrition and quality of life, contributing to metabolic disorders and frailty in the elderly, yet its cellular and molecular basis remains poorly understood. By integrating single‐cell RNA and spatial transcriptomics sequencing, we systematically mapped murine taste bud aging across five developmental stages from neonatal to aged. Our findings reveal that age‐associated taste impairment is driven by the progressive depletion of stem/progenitor cell differentiation cap …

19.08.2026journal-article

Journal of Human Hypertension

The association between mobility and asleep blood pressure alterations in frail and non-frail adults 80 years and older

Fernando G. Blauth, Fernando L. Scolari, Laís A. S. Vilar, Victor C. B. Pontes, Vanessa B. V. de Carvalho, Júlio C. Moriguti, Nereida K. Lima

Abstract The influence of mobility on asleep blood pressure among adults aged 80 years and older, particularly considering frailty, remains poorly understood. This cross-sectional study aimed to examine the association between objectively measured mobility parameters and asleep blood pressure alterations in a frail and non-frail population aged 80 years and older. Seventy-one participants (mean age 85 ± 4 years; 33 non-frail and 38 frail) completed both ambulatory blood pressure monitoring (ABPM) and objective mobi …

19.08.2026journal-article

Horizonte Sanitario

<b>Adaptación transcultural </b><b>de la escala de estrés en personas con hipertensión arterial</b>

Doris Berdazco Pintado, Ana Laura Carrillo Cervantes, Nissa Yaing Torres Soto, Reyna Torres Obregón

Objective: To adapt and validate the "Stress Scale for People with Arterial Hypertension" for its subsequent use in the assessment of stress in hypertensive patients. Materials and methods: An observational, cross-sectional study was conducted. An anonymous and voluntary survey was administered. The sample consisted of 181 individuals (110 women and 71 men) residing in the city of Saltillo, Coahuila, Mexico, with diagnosis of arterial hypertension, with a mean age of 55.34 years (SD = 13.93). The instrument include …

19.08.2026journal-article

Australasian Journal on Ageing

Upskilling Allied Health Professionals and Judo Coaches to Teach Safe Falling Skills to Older Adults: A Train‐the‐Trainer Intervention

Agathe Daria Jadczak, Meera Verma, Michael Headland, Renuka Visvanathan

ABSTRACT Objectives Learning safe falling skills, adapted from judo, is a promising strategy to reduce the risk of falls and fall‐related injuries in older adults. This study aimed to upskill allied health professionals and judo coaches to teach safe falling skills to community‐dwelling older adults. Methods A Train‐the‐Trainer program including a 2‐day workshop (13 h) on teaching safe falling and how to work with older adults, followed by weekly attendance at an 8‐week judo‐based safe falling program for older adu …

19.08.2026journal-article

JMIR Aging

Demoralization and Mental Disorders in Community-Dwelling Older Adults: Cluster Analysis

Alice Onofrio, Maria Ferrara, Ilaria Domenicano, Martino Belvederi Murri, Tommaso Toffanin, Maria Giulia Nanni, Alessandra Canuto, Kerstin Weber, Jana Volkert, Holger Schulz, Martin Härter, Sylke Andreas, Luigi Grassi

Abstract Background Demoralization negatively affects the quality of life, especially in people with mental disorders. Objective This study aims to assess demoralization in a cohort of community-dwelling older adults, to identify groups of individuals who share similar characteristics in terms of mental health conditions and the severity of demoralization domains, and to investigate the different characteristics across these groups. Methods Participants were enrolled in 3 centers as part of the cross-sectional Ment …

19.08.2026journal-article

Gerontology

construction and evaluation of sarcopenia risk prediction model for non-obese older adults

Xin Liu, Shichen Wang, Yanan Wei, Qian Xue, Jingtong Wang

Introduction: Sarcopenia is common in older adults, with distinct features in non-obese individuals. This study developed and validated a nomogram to predict sarcopenia risk specifically in non-obese older adults. Methods: Data from 1,654 CHARLS participants were used for model development and internal validation, and 263 NHANES participants for external validation. LASSO regression selected predictors. A nomogram was constructed and assessed using AUC (discrimination), calibration curves (accuracy), and decision c …

19.08.2026journal-article

Frontiers in Psychiatry

Effects of visual art therapy on cognitive function in older adults: a systematic review and meta-analysis

Zhenhua Guo, Yingcong Liu, Shan Zhu, Yupeng He

Objective To systematically review the evidence on the effects of visual art therapy on global cognitive function in older adults, and to examine its impact on verbal fluency, naming ability, and activities of daily living. Methods A systematic search was conducted in PubMed, Web of Science, Embase, the Cochrane Library, China National Knowledge Infrastructure (CNKI), the Chinese Biomedical Literature Database, Wanfang Database, and VIP Database for randomized controlled trials (RCTs) published from database incept …

19.08.2026journal-article

Journal of the American Geriatrics Society

Geriatric Medicine Competencies in Postgraduate Training Programs Across Specialties

Janani Thillainadesan, Grace Pearson, Gregory M. Ouellet, Marcia C. Mecca, Terri R. Fried, Tim J. Wilkinson

ABSTRACT Background Aging populations require physicians skilled in competencies essential for the care of older adults. The extent to which such geriatric competencies are included in non‐geriatric postgraduate medical training programs is not known. Therefore this study examined the inclusion of 13 geriatric competencies in postgraduate training programs in Australia and New Zealand, the United Kingdom, and the United States. Methods Thirteen core geriatric competencies were identified and defined: aging physiolo …

19.08.2026journal-article

Frontiers in Aging Neuroscience

Tai Chi for improving motor symptoms in Parkinson’s disease patients: a systematic review of mechanisms

Zhi Li, Xiupan Wei, Pengyi Gao, Jiayi Zhang, Qian Wang, Pei Wang, Ting Zhou, Hongxing Wang

Background In recent years, Tai Chi (TC) training has played an increasingly important role in the management of motor disorders in Parkinson’s disease (PD) patients. A thorough understanding of the therapeutic mechanisms of TC is crucial for optimizing its clinical efficacy. The long-term practice of TC has been shown to enhance patients’ balance and postural stability, thereby reducing the risk of falls and improving their walking ability. Objectives This systematic review seeks to elucidate the mechanisms throug …

19.08.2026journal-article

EDUJAVARE: International Journal of Educational Research

Multicultural Education from an Islamic Perspective and Its Relevance to the Lives of the People of Papua

Muhammad Irwan Putra, Yudha Dharma Buana, Florensia Ruri Renaningtyas

This article specifically examines the concept of multiculturalism from an Islamic perspective by relating it to the social realities of communities in Papua. Based on a conceptual and normative study, Islam views plurality as sunnatullah, meaning that diversity is part of God’s natural order; therefore, universal values such as justice, brotherhood (ukhuwah insaniyyah), and tolerance constitute important foundations for peaceful social life amid differences. Through an integrative approach that connects the teachi …