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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
24.08.2026journal-article

Frontiers in Medicine

High-intensity focused ultrasound combined with syndrome differentiation-based individualized herbal therapy and 12-month outcomes in patients with adenomyosis: a prospective non-randomized study

Cuiling Zhang, Lijun Zhang, Shuping Zhao, Yanyan Huang, Liangqian Zhao, Rongxing Wang, Yuling Wang, Deyan Sun, Yongsheng Ma, Qiuling Shi

Objective To evaluate the association of high-intensity focused ultrasound (HIFU) combined with syndrome differentiation-based individualized traditional Chinese medicine (TCM) herbal therapy with 12-month clinical outcomes compared with HIFU monotherapy in patients with adenomyosis (AM). Methods This prospective non-randomized, patient-preference, parallel-controlled study enrolled 88 patients with adenomyosis between November 2021 and November 2023; 87 completed 12-month follow-up and were analyzed (HIFU, n = 45; …

24.08.2026journal-article

Journal of Early Hearing Detection and Intervention

Exploring Speech-Language Pathologists’ Development of Hearing Loss Health Literacy

Ellie Cooper, Krystal L Werfel

Purpose. This qualitative study examined how speech-language pathologists (SLPs) develop hearing loss health literacy through academic training and on-the-job experience. Specifically, it explored SLPs’ perspectives on how graduate coursework and clinical exposure contributed to their readiness to work with children who are deaf or hard of hearing (DHH). Method. Participants included 48 SLPs with a range of specialty academic coursework and on-the-job experience working with children who are DHH. SLPs were categori …

24.08.2026journal-article

Audiology Research

The Temporal Resolution Needed for Speech Intelligibility Assessed with Mosaic Speech: Effects of Block Duration, Age, and Word Familiarity

Gerard Remijn, Yuna Uzuhashi, Emi Hasuo, Kazuo Ueda, Yoshitaka Nakajima

Background/Objectives: Mosaic speech was used to further investigate the auditory system’s temporal resolution needed for speech intelligibility. Mosaic speech is a form of degraded speech segmented in frequency × time blocks with no discernible temporal fine structure and with degraded amplitude envelope cues. Methods: We performed a listening experiment with mosaic speech consisting of 20 frequency bands segmented into 20, 40, 80, 160, and 320 ms. Younger listeners (<25 years; n = 20), with self-reported normal h …

24.08.2026journal-article

Language and Speech

Prosody Influences Real-Time Processing When Grammar Allows but Plays Less of a Role in Final Interpretation: An Eye-Tracking Study on VP Ellipsis and Stripping

Haerim Hwang

This study examines whether prosody affects how people process and interpret two types of sentences that both have missing material but differ in ambiguity. Stripping sentences (e.g., Grandma hugged the kid at home and Grandpa too ) are ambiguous because the argument after and can be read as either the subject of the missing verb or the second object of the audible/visible verb. In contrast, verb phrase (VP) ellipsis sentences (e.g., Grandma hugged the kid at home and Grandpa did too ) are unambiguous, only allowin …

24.08.2026journal-article

Arthroscopy

Bone Marrow‐Derived Cell Therapy Plus Core Decompression Enhanced Efficacy Compared With Core Decompression Alone in Treating Osteonecrosis of the Femoral Head: A Systematic Review and Meta‐analysis of Randomized Controlled Trials

Xiao‐Na Xiang, Hao‐Nan Wang, Hong‐Chen He, Jian Li, Cheng‐Qi He

Purpose To systematically determine whether bone marrow‐derived cell therapy combined with core decompression could result in better improvements in pain relief, function, and radiographic progression, higher survival of hip joints, and an equivalent rate of adverse events than hip‐preserving techniques alone in individuals with osteonecrosis of the femoral head (ONFH). Methods We searched randomized controlled trials of core decompression with or without cell‐based therapy in osteonecrosis of the femoral head acro …

24.08.2026journal-article

American Journal of Perinatology

Early speech therapy is associated with decreased length of stay in preterm infants <28 weeks gestational age.

Amanda Mosher, Jennifer Check, Kaylee Freid, Jessica Walker, Peter Porcelli, Parvesh Mohan Garg

Objective The aim of this study was to assess the timing of speech therapy (ST) on the length of stay (LOS) and developmental outcomes at 6 and 12 months in preterm infants. Study design: Infants delivered 24-28 weeks gestational age (GA) who received ST from 2022-2025 were enrolled. Analysis comparing postmenstrual age (PMA) at speech therapy initiation determined two cohorts. Demographic, imaging studies and clinical outcomes were compared between cohorts using R-software. Multivariable regression adjusting for c …

24.08.2026journal-article

Language, Speech, and Hearing Services in Schools

Promoting Children's Rights Through Breastfeeding Support: A Randomized Controlled Trial of a Speech-Language Pathologist–Led Intervention Among Migrant Mothers in Primary Health Care

Ana Cláudia Lopes, Pedro Sá Couto, Marisa Lousada

Purpose: This randomized controlled trial evaluated a culturally adapted breastfeeding intervention led by speech-language pathologists (SLPs) for migrant mothers, grounded in the Convention on the Rights of the Child (CRC). The intervention addressed the rights to nondiscrimination (CRC Article 2), best interests of the child (CRC Article 3), survival and development (CRC Article 6), highest attainable standard of health (CRC Article 24), full potential (CRC Article 29), and cultural identity (CRC Article 30). The …

24.08.2026journal-article

Leukemia

TP53-mutant CHIP defines a pro-inflammatory phenotype and predicts adverse outcomes after CAR T-cell therapy

Giulia Rappa, Frank Ziemann, Kieron White, Linus Kruk, Samar Shamas, Amelie Muth, Kayleen Shi, Cristina Zucchinetti, Savanna Süß, Maja Rothenberg-Thurley, Alessandra Holzem, Tobias Tix, Agnese Petrera, Bianka Ksienzyk, Charlotte Bentenrieder, Katharina S. Götze, Fabian Müller, Veit Bücklein, Kai Rejeski, Marion Subklewe

Abstract Clonal hematopoiesis of indeterminate potential (CHIP) has been well-characterized in patients receiving chemotherapy and hematopoietic cell transplantation. However, its immunologic relevance and potential role in modulating chimeric antigen receptor T-cell (CAR-T) therapy-related toxicities, inflammation, and clinical outcomes remains incompletely defined. In this exploratory study of 104 CAR-T recipients, we investigated the prognostic impact of pre-existing CHIP clones on toxicity and survival, and exa …

24.08.2026journal-article

Pakistan Journal of Medical Sciences

Efficacy of lenvatinib combined with sintilimab and transcatheter arterial chemoembolization in conversion therapy for unresectable hepatocellular carcinoma

Jianwu Long, Jingli Zheng, Shiyi Chen, Peng Ou, Xianzhou Lu

Objectives: To compare the efficacy of lenvatinib combined with sintilimab versus transcatheter arterial chemoembolization (TACE) in the conversion therapy for unresectable hepatocellular carcinoma (HCC). Methodology: A retrospective analysis of the clinical data of 153 patients with unresectable HCC admitted to the Affiliated Hospital of Nanhua University from January 2023 to December 2024 was performed. According to the treatment regimens, the patients were divided into two groups: the study group (n=79) treated …

24.08.2026journal-article

Small

Driving Drugs Deeper: Force‐Driven Microneedle Systems for Active Therapy and Their Road Towards Clinical Implementation

Majed Amini, Phoebe Li, Hamed Shahsavan, Mahla Poudineh

ABSTRACT Transdermal delivery of macromolecules and biologics is constrained by the barrier function of skin. First‐generation microneedle arrays address this issue by penetrating the stratum corneum; however, their passive, diffusion‐based release limits delivery depth, kinetics, and adaptability. In this review, we discuss force‐driven microneedles (F‐MNs) as a shift from passive permeation to active propulsion. F‐MNs integrate mechanisms that generate localized physical driving forces to rapidly and controllably …

23.08.2026journal-article

Quality in Sport

Efficacy and safety of semaglutide and tirzepatide in the therapy of obesity and type 2 diabetes – current state of knowledge

Julianna Rozalia Chyl, Łukasz Kowalewski, Oliwia Barbara Gutowska, Weronika Nowak, Wiktoria Magdalena Kostuch, Agata Zimon, Maria Aleksandra Styczyńska, Olga Błażowska-Danielska, Martyna Zielnik, Alicja Jurewicz

Background. The diabesity epidemic (obesity and type 2 diabetes) requires a shift from a glucocentric to a holistic approach, making weight reduction a clinical goal equal to glycemic control. Incretin-based therapies (semaglutide, tirzepatide) represent a breakthrough due to their pleiotropic effects. Aim. This study analyzes their efficacy, safety, molecular mechanisms, and cardio/nephroprotection in light of recent trials and guidelines. Material and methods. PubMed and Google Scholar were searched (2018–2026) u …

23.08.2026journal-article

Smart Molecules

Hj ‐aggregates of quinoline‐fused boron‐dipyrromethene nanoparticles for near‐infrared dualmodal photodynamic and photothermal therapy

Bo Zhang, Chuang Du, Yuewen Yang, Dongping Xu, Xin‐Dong Jiang, Hui‐Xin Liu, Gaowu Qin

Abstract Development of boron‐dipyrromethene (BODIPY)‐based phototherapeutic agents integrating photodynamic and photothermal therapy is limited by restricted modifiable sites on traditional scaffolds. Herein, we report a quinoline‐fused cyclic pyrrole Npy generated by an lithium diisopropylamide‐catalyzed [3 + 2] cyclization, which incorporates a nitrogen atom into a rigid polycyclic π‐system. Using this pyrrole Npy, a symmetric photosensitizer Npy‐BDP with absorption at 660 nm was prepared with a singlet oxygen q …

23.08.2026journal-article

British Journal of Occupational Therapy

Natural support networks’ role in habit formation for adults with obesity: A qualitative study using research circles

Jeanette Reffstrup Christensen, Julie Katrine Karstensen, Chloe Muntefering, Line Nørgaard Remmen, Kim lee, Christina Jessen-Winge

Introduction: Obesity poses a significant global health threat, with weight loss programmes often struggling to sustain long-term results. Everyday habits and lifestyle practices are widely recognized as critical components for maintaining weight loss over time. Despite the potential of natural support networks (NSNs) in aiding weight loss efforts, their specific role remains unclear in supporting habit formation. The aim was to explore how adults with obesity, occupational therapists (OTs), and researchers in obes …

23.08.2026journal-article

Occupational Medicine

Comparison of Job Performance, Job Satisfaction, and Job Commitment Before, During, and After the Menstrual Cycle among Teachers

A Jafari, A Mehdad

Background: The menstrual cycle and its related factors can influence women's job performance, job satisfaction, and job commitment at each stage of the cycle. This is due to the different hormonal and physiological changes that occur in women's bodies, along with their consequent mood effects. Therefore, the purpose of the present study was to compare job performance, job satisfaction, and job commitment in three stages: before, during, and after the menstrual period among female teachers. Methods: This descriptiv …

23.08.2026journal-article

International Journal For Multidisciplinary Research

Interpretable Brain-computer Interface for Emotion-aware Thought-to-speech using Eeg Signal Decoding

Abhimanyu Singh, Edith Paulin S

Restoring effective communication for people with severe speech impairment remains a most important concern in assistive healthcare. Electroencephalography (EEG)-Based Brain–Computer Interfaces (BCI) can decode imagined speech from neural activity; however, existing techniques have been limited by a lack of interpretability, reduced robustness across users, and inadequate integration of emotional context. In this study, we present an Interpretable Brain–Computer Interface for Emotion-Aware Thought-to-Speech that in …

23.08.2026journal-article

Journal of Dental Health and Oral Research

From Static Restorations to Adaptive Prosthodontics: Digital Twins, Occlusal Intelligence and Predictive Functional Rehabilitation: A Narrative Review

Douglas Javier Silva Salas, Ana Fernandez Sanchez, Arlet Sierra Plasencia, Arlety Acosta Muy, Yumey La Torre Rivero, Alejandra Hernandez Gutierrez

Digital technologies have transformed prosthodontic rehabilitation, yet treatment planning remains largely static, based on anatomical records captured before treatment begins. Digital twins offer a different model, integrating anatomical, functional, biomechanical and behavioral patient data into a computational representation that is updated throughout the care process. The aim of this narrative review was to evaluate the extent to which patient-specific digital twins can advance prosthodontics from a restorative …

23.08.2026journal-article

Journal of Oral Rehabilitation

Variables That Influence Changes in Temporomandibular Joint Structure

Jeff C. Nickel, Laura R. Iwasaki, Mansur Ahmed, Saulo L. Sousa Melo, Dillon Moya, Hongzeng Liu, Dongseok Choi, Yoly Gonzalez

ABSTRACT Background There are no objective measures which forecast longitudinal changes in the temporomandibular joint (TMJ). Objective To identify variables that predicted longitudinal changes in TMJ structure. Methods Over an average of 8 years, baseline and follow‐up computed tomography and magnetic resonance imaging data were reviewed by calibrated radiologists. Baseline to follow‐up changes in TMJ structure were grouped according to A = no changes, B = got better and C = got worse. For the current investigatio …

23.08.2026journal-article

Diabetes, Obesity and Metabolism

Responders Vs. Non‐Responders or How to Predict the Response to GLP ‐1 or GLP ‐1/ GIP Receptor Agonist Therapy

Alina Kuryłowicz, Leszek Czupryniak

ABSTRACT Background Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and dual GLP‐1/GIP receptor agonists have transformed the pharmacological management of type 2 diabetes (T2D) and obesity, yet substantial interindividual variability in treatment response remains a defining clinical challenge. Methods Narrative review. PubMed was searched to 25 May 2026 (English language, human studies, 2005–2026) for biological, genetic, metabolic, hormonal, behavioural and psychosocial predictors of differential response. E …

23.08.2026journal-article

International Journal on Advanced Science, Engineering and Information Technology

Objective Motion Tracking for Rehabilitation: Quantitative Assessment Using Pose Estimation

Kok Swee Sim, Mahda Laina Arnumukti

Evaluation of the effectiveness of rehabilitation therapy is often based on patient outcomes and functional improvement over time. However, traditional approaches are subjective and heavily influenced by expert perspectives and perceptions, which can lead to inconsistencies in research. This study developed a motion measurement system that improves body positioning by using computer vision techniques to quantitatively assess elbow flexibility and range of motion during rehabilitation. The system uses a novel postur …

23.08.2026journal-article

Discover Public Health

Occupational distribution of acute stroke patients at a tertiary care center in Iran as a descriptive cross-sectional study

Samad Shams Vahdati, Alireza Ala, Naeimeh Hosseinzadeh, Maryam Rahimpour Asenjan, Gisou Gorashian, Amirreza Jabbaripour Sarmadian

Abstract Background Acute stroke remains a major public health concern, yet limited data exist on its distribution across occupational groups. This study aimed to investigate the occupational profiles of patients with acute stroke at a tertiary care center in Iran. Methods This descriptive, cross-sectional study was conducted from January to July 2020 in the emergency department of Imam Reza Hospital, Tabriz, Iran. Using census sampling, all confirmed stroke patients were enrolled. Demographic information, includin …

23.08.2026journal-article

Occupational Medicine

Prevalence of Acute and Chronic Pain and Associated Factors in COVID-19 Patients with an Occupational Health Approach

H Hoboubati, M Khoshbin, AM Abuei Mehrizi, M Sharif Yazdi, H Salehinia, MH Ahmadieh

Introduction: The COVID-19 pandemic and the associated symptoms have had significant impacts on individuals' health and functional abilities. This study aims to investigate the prevalence of acute and chronic pain among inpatients during the years 2020 to 2022 and explore the potential consequences on their functional capacity and return to work. Materials and Methods: This study was conducted in a selected hospital in Yazd Province. The study population consisted of 384 patients. Data were collected through a revi …

23.08.2026journal-article

International Journal of Scientific Research in Science and Technology

Smart Glove for Speech Disabled People

Ganesh Hiratot, Gauri Ingale, Vaibhav Bhujbal, Durvesh Suryavanshi, Prajakta Deshmukh

Communication is the most basic form of human interaction, yet for millions of individuals with speech and hearing impairments, it remains a significant hurdle. This project presents a "Smart Glove" designed to act as a real-time translator between manual sign language and spoken language. By employing five high-precision flex sensors (one for each finger) and a three-axis accelerometer, the system captures the intricate geometry and orientation of hand movements. These physical parameters are converted into digita …

23.08.2026journal-article

Physiotherapy Research International

Effects of Adding Incentive Spirometry to Hospital‐Based Cardiovascular Rehabilitation on Pulmonary Complications, Hospital Length of Stay, and Clinical‐Functional Recovery After Cardiac Surgery: A Randomized Controlled Trial

Bruna Elise da Silva Messias, Thamires Alessandra Silveira da Silva, Rafaela Anversa Schreiner, Letícia Torres, Jéssica Bischoff, Taís Flores de Oliveira, Vinicius Peringer, Francine Manara Bortagarai, Mateus Diniz Marques, Bruna Eibel, Carine Cristina Callegaro

ABSTRACT Background and Purpose This study investigated the effects of combining incentive spirometry with cardiac rehabilitation compared with cardiac rehabilitation alone on postoperative pulmonary complications, clinical‐functional recovery, and hospital length of stay in patients undergoing cardiac surgery. Methods Randomized controlled trial was conducted from May 2019 to October 2023 in two hospitals, including 46 inpatients undergoing cardiac surgery. Participants were assigned to incentive spirometry plus c …