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Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
21.08.2026journal-article

Environmental Science & Technology

Nontarget Analysis of the Volatile and Semivolatile Chemical Profile of Wildland Firefighter Gear: Insight into Occupational Exposure and Health Implications

Patrica-Ivy Agorsor, Husam Kafeenah, Margaret D. Taiwo, Robin Verble, Michael O. Eze

Abstract Prescribed fire releases a complex mixture of volatile and semivolatile organic compounds to the environment. Firefighters are directly exposed to these hazardous mixtures through occupational activities. This study investigated the volatile and semivolatile chemical contamination profile of firefighter protective gear and the effectiveness of laundering as a decontamination strategy. Our results revealed that firefighter gear accumulated a broad spectrum of combustion-derived contaminants, predominantly c …

21.08.2026journal-article

European Heart Journal: Acute Cardiovascular Care

Injectable antiplatelet therapies in acute coronary syndromes: Current status and Emerging Therapies. A position paper of the Task Force of Antithrombotic therapy of the ACVC

Uwe Zeymer, Sogol Koolaji, Diego Araiza-Garaygordobil, Peter Clemmensen, Mario Gramegna, Konstantin A Krychtiuk, Christoph B Olivier, Andrea Rubboli, Benedikt Schrage, Christophe Vandenbriele, Kurt Huber, Diana A Gorog

Abstract Injectable antiplatelet agents can provide immediate and effective platelet inhibition in patients with acute coronary syndromes (ACS). These agents are able to overcome many of the limitations of oral antiplatelet agents, and maybe of particular benefit in patients with ST-elevation myocardial infarction (STEMI), especially those presenting with cardiogenic shock or rescuscitated cardiac arrest. In these patients, factors such as vomiting, altered physiology, sedation, mechanical ventilation or therapeuti …

21.08.2026journal-article

International Journal of Molecular Sciences

Single-Exposure Prophylactic Transcranial Nano-Pulsed Laser Therapy Promotes Functional Resilience Following Mild Blast-Induced Neurotrauma

Nikita Gupta, Katherine N. Sheffield, Mohammadhossein Khanmirzaei, Auston C. Grant, Jutatip Guptarak, Ian J. Bolding, Kathia M. Johnson, Rinat O. Esenaliev, Donald S. Prough, Maria-Adelaide Micci

Blast-induced traumatic brain injury is a prevalent and underreported condition, particularly among military service members, for whom effective prophylactic interventions are lacking. Nano-pulsed laser therapy (NPLT) is a non-invasive neuromodulatory approach that delivers short pulses of near-infrared light to generate optoacoustic effects within cerebral tissue and has previously demonstrated therapeutic benefit following TBI. In this study, we evaluated whether a single pre-exposure application of NPLT could co …

21.08.2026journal-article

Applied Sciences

Manual Diaphragm Therapy and Masseter Muscle Activity in Healthy Young Women: An Exploratory Randomized Study of sEMG, Mandibular Motor Function, and Perceived Stress

Joanna Golec, Monika Nowak, Joanna Balicka-Bom, Sara Gamrot, Iwona Sulowska-Daszyk, Monika Michalik, Jędrzej Golec, Aneta Wieczorek

This exploratory randomized study examined whether manual diaphragm therapy is associated with masseter muscle activity, mandibular motor function, and perceived stress in healthy women. Forty-two asymptomatic women aged 20–30 years were randomized to an intervention group (n = 20), receiving six sessions over two weeks, or a no-intervention control group (n = 22). Before and after the intervention period, bilateral masseter surface electromyography (sEMG) was recorded at rest and during standardized mandibular mot …

21.08.2026journal-article

Tạp chí Y học Quân sự

ĐÁNH GIÁ THỰC TRẠNG Ô NHIỄM HƠI TNT TRONG MÔI TRƯỜNG LAO ĐỘNG VÀ NHIỄM TNT NGHỀ NGHIỆP TẠI MỘT SỐ KHO QUÂN KHÍ NĂM 2025

Đào Thị Lê Dung, Hoàng Thị Lan Anh, Phạm Quyết Chiến, Nguyễn Văn Đông, Ngô Quang Hải, Nguyễn Kiên Cường

Mục tiêu: Mô tả thực trạng ô nhiễm hơi TNT trong môi trường lao động, nhiễm TNT nghề nghiệp ở người lao động và xác định nhóm công việc có nguy cơ phơi nhiễm cao tại một số kho quân khí, năm 2025. Đối tượng và phương pháp: Nghiên cứu mô tả cắt ngang 711 người lao động và 418 mẫu môi trường lao động tại 16 đơn vị kho quân khí, từ tháng 9-12/2025. Đánh giá kết quả theo QCVN 03:2019/BYT và Quy trình kĩ thuật thường quy của Viện Sức khỏe nghề nghiệp và Môi trường. Kết quả: Tỉ lệ mẫu TNT trong không khí tại nơi làm việc …

21.08.2026journal-article

ACS Materials Letters

Biomaterial-Assisted Strategies to Improve Islet Encapsulation and Transplantation for Type 1 Diabetes Therapy

Haofei Li, Peihua Long, Wenxuan Qin, Xingyu Chen, Chuanlong Liao, Haoting Shi, Yang Liu, Lu Gao

Abstract Islet transplantation is a promising therapy for type 1 diabetes mellitus (T1DM), but its clinical application is limited by host immune rejection and insufficient mass transfer. Biomaterial-assisted strategies hold the potential to address these challenges by providing an immune-isolated microenvironment and facilitating nutrient and oxygen supplementation. Therefore, this review outlines the primary bottlenecks in islet transplantation and then discusses current biomaterial engineering approaches to over …

21.08.2026journal-article

Frontiers in Immunology

YBX1 as an adaptive RNA hub in cancer: linking state-dependent RNA regulation to tumor immunity, metabolic reprogramming, and therapy resistance

Zhang XiaoTian, Wang YiTong, Feng Chongchong

Y-box binding protein 1 (YBX1) has been implicated across an unusually broad range of malignancies and processes: immune remodeling, epithelial plasticity, metabolic rewiring, epitranscriptomic reading, and resistance to chemotherapy, targeted agents, and checkpoint blockade. A linear one-gene/one-pathway oncogene model does not readily accommodate this breadth. We argue that the apparent diffuseness reflects a context-dependent regulatory node rather than experimental noise, and develop the hypothesis that YBX1 ac …

21.08.2026journal-article

The Oncologist

IUC26698-96 Durvalumab + BCG therapy in BCG-naïve, high-risk NMIBC: efficacy and safety analyses from POTOMAC

S Hussain, N Shore, H Nishiyama, J Palou Redorta, M Krawczynski, A Seyitkuliev, F Guerrero-Ramos, M Kato, T Powles, M De Santis

Abstract Background Durvalumab (D) plus BCG induction (I) + maintenance (M) vs BCG (I+M) demonstrated statistically significant, clinically meaningful improvement in disease-free survival (DFS) in patients with BCG-naïve, high-risk non-muscle-invasive bladder cancer (NMIBC; POTOMAC, NCT03528694). We report in-depth efficacy and safety analyses for D+BCG (I+M) vs BCG (I+M). Methods Patients were randomized 1:1:1 D+BCG (I+M), D+BCG (I), or BCG (I+M). For D+BCG (I+M) vs BCG (I+M), we report time to cystectomy (TTC; se …

21.08.2026journal-article

Neuro-Oncology Advances

Combination of EZH2 and MEK inhibitors as an Effective Therapy for Neurofibromatosis Type 1-Associated Malignant Peripheral Nerve Sheath Tumors

Sogo Oki, Yukitomo Ishi, Shigeru Yamaguchi, Manabu Natsumeda, Christine A Pratilas, Michiyuki Hakozaki, Hideki Tanizawa, Zen-ichi Tanei, Miki Fujimura

Abstract Background Neurofibromatosis type 1 (NF1)–associated malignant peripheral nerve sheath tumors (MPNSTs) are aggressive sarcomas with poor outcomes and limited therapeutic options. Although mitogen-activated protein kinase kinase (MEK) inhibitors are active in benign plexiform neurofibromas, their efficacy in MPNST treatment is modest. Enhancer of zeste homolog 2 (EZH2) inhibitors are preclinically efficacious in MPNST treatment, but their mechanisms of action remain unclear. We evaluated the therapeutic pot …

21.08.2026journal-article

Applied Sciences

Rehabilitation of Shoulder Disorders: An ICF-Oriented Lexical Network Analysis of the Literature

Daniele Coraci, Gianluca Regazzo, Gianpaolo Ronconi, Gabriele Santilli, Cristina Razzano, Lucrezia Tognolo, Stefano Masiero

(1) Background: The continuous growth of rehabilitation literature makes evidence synthesis increasingly challenging. Lexical network analysis may provide quantitative information on the organization of scientific knowledge. This study aimed to characterize the shoulder rehabilitation literature through an International Classification of Functioning, Disability and Health (ICF)-oriented lexical network approach. (2) Methods: PubMed was searched for papers on shoulder rehabilitation published from 2016 to 2025. ICF- …

21.08.2026journal-article

Healthcare

Thematic Structure of Clinical Rehabilitation Research in the Early Post-Pandemic Period: An LDA-Based Analysis of Publications from 2022 to 2025

Alina Alshevskaya, Ivan Khutornoy, Natalia Sivitskaya, Marat Fatkhullin, Elena Aksenova

Background/Objective: Recent advances in scientometric topic modeling have enhanced the capacity to rapidly assess evolving research priorities. This study aimed to characterize the thematic reorganization of clinical rehabilitation research during the early post-pandemic period and to compare how an Latent Dirichlet Allocation (LDA)-derived topic structure, SciVal, and OpenAlex represent this interdisciplinary research domain. Methods: Titles of 55,711 publications on clinical rehabilitation (2022–2025) were analy …

21.08.2026journal-article

Revista Ibero-Americana de Humanidades, Ciências e Educação

CONTRIBUIÇÕES DA TERAPIA COGNITIVO-COMPORTAMENTAL PARA A SAÚDE MENTAL DA POPULAÇÃO LGBT: UMA REVISÃO INTEGRATIVA DA LITERATURA

Joel Leal Pinto de Souza Moura, Paula Oliveira Silva, Silvia Helena Modenesi Pucci

Estudos descrevem que a população LGBT apresenta maior vulnerabilidade a transtornos mentais e sofrimento psicológico em comparação à população heterossexual e cisgênero, associada à exposição a estressores sociais crônicos, como preconceito, discriminação e exclusão. Nesse contexto, a Terapia Cognitivo-Comportamental é amplamente reconhecida como uma abordagem baseada em evidências para o manejo de condições em saúde mental. Objetivo: Analisar as contribuições de intervenções fundamentadas na TCC para a saúde ment …

21.08.2026journal-article

Power and Education

Defending the university against bad-faith policy interventions: Equality, diversity and inclusion, free speech, and institutional power

Sean Walton, Syra Shakir

Recently, there has been a resurgence of claims that equality, diversity, and inclusion (EDI) initiatives threaten freedom of speech in UK higher education. Using the Alumni for Free Speech (AFFS) report (2025) as an example of this, we argue that the opposition between free speech and EDI is a politically manufactured false binary that obscures how power, voice, and harm are unevenly distributed within universities. Drawing on Critical Race Theory, decolonial scholarship, Black Radical Politics, and critical polic …

21.08.2026journal-article

Journal of Health and Allied Sciences NU

Effect of Music Therapy on Physiological Parameters Among Patients on Mechanical Ventilation

Varsha Evare, Nutan Podar

Objectives Patients on mechanical ventilation in intensive care units often experience physiological instability. Music therapy is considered a supportive non-pharmacological intervention. The present study aimed to assess the effect of Carnatic music therapy (Raga Ananda Bhairavi) on physiological parameters in patients receiving mechanical ventilation. Material and Methods The study employed a single-group quasi-experimental pre-test and post-test design. The study involved 50 adult ventilated patients who were s …

21.08.2026journal-article

Medicine

Complete remission of Helicobacter pylori-negative gastric MALT lymphoma following eradication therapy

Hui Chen, Jingtong Tang, Lin Mo, Xi Wang, Guobin He

Rationale: Gastric mucosa-associated lymphoid tissue (MALT) lymphoma is typically associated with Helicobacter pylori infection; however, approximately 10% of cases are H pylori -negative. Management guidelines differ between the European Society for Medical Oncology (ESMO) and the National Comprehensive Cancer Network (NCCN) regarding first-line treatment for these patients. Here, we report a case of H pylori -negative gastric MALT lymphoma that achieved complete remission following standard eradication therapy. P …

21.08.2026journal-article

Medicine

Robot-assisted rehabilitation therapy for adhesive capsulitis

Seung Min Ryu, Jeong Hee Park, Woosung Choi, Joonhyoung Hong, Hui Ben, Hangsik Shin, In-Ho Jeon

Background: Adhesive capsulitis, commonly known as frozen shoulder, presents with pain and restricted movement. Treatments include physical therapy focusing on stretching exercises, intra-articular corticosteroid injections, and surgical intervention if conservative management fails. The efficacy of robot-assisted rehabilitation therapy (RART) for adhesive capsulitis remains unexplored, necessitating clinical application and analysis. Methods: A prospective, randomized controlled trial was conducted involving patie …

21.08.2026journal-article

Archives of Health Science and Research

Executive Functions in Children with Speech Sound Disorders: A Qualitative Content Analysis of Studies Conducted in Türkiye

Nurdan CANKUVVET, Gizem Nur GÖR

Objective: Speech sound disorder (SSD) is common developmental communication disorders increasingly viewed as embedded within broader cognitive processes. Executive functions (EF) support speech production, phonological representation, and self-regulation; however, their multidimensional nature is not consistently reflected in SSD research. This study aimed to systematically examine how EF have been conceptualized, operationalized, and reported in studies of children with SSD conducted in Türkiye. Methods: A qualit …

21.08.2026journal-article

The Ukrainian Journal of Clinical Surgery

Neoadjuvant Hormone Therapy for Hormone-Receptor-Positive, HER2-Negative Breast Cancer: Experience of the Transcarpathian Anticancer Center

F. M. Pavuk, K. Ye. Rumyantsev, S. M. Chobei, M. F. Rishko

Objective. To summarize the experience of using neoadjuvant hormone therapy for hormone-receptor-positive, HER2-negative breast cancer in the real-world clinical practice of the Transcarpathian Cancer Center and to evaluate its impact on the frequency of breast-conserving surgery, long-term oncological outcomes, and patients’ quality of life.Materials and Methods. This retrospective study included 1,612 patients with hormone-receptor-positive, HER2-negative breast cancer who received treatment between 2010 and 2024 …

21.08.2026journal-article

INTERNATIONAL JOURNAL OF MULTIDISCIPLINARY RESEARCH AND ANALYSIS

Occupational Stress, Coping, and Work Motivation among Members of the Criminal Justice System: A Conceptual Paper

Shirleen Martins, Dr. Shahnaz Sheibani, Dr. Bilal Ahmad Lone

Members of the Criminal Justice System operate within high-stakes, ethically demanding, and emotionally taxing environments that may significantly influence their occupational stress, coping strategies, and work motivation. Drawing upon Person–Environment Fit theory, Coping Theory, and Herzberg’s Two-Factor Theory, this conceptual paper proposes an integrative framework explaining the interrelationships among occupational stress, coping, and work motivation in Criminal Justice System professionals. Ten hypotheses a …

21.08.2026journal-article

Journal of Marital and Family Therapy

Relational Therapy in Post‐Incarceration Reentry: A Scoping Review

Eman Tadros, Thita Lamsam, Chandni Anandha Krishnan

ABSTRACT An estimated 600,000 individuals returning home after incarceration each year face significant challenges that constrain their reentry and reintegration into society. A scoping review was conducted on how relational therapy is discussed in the literature on post‐incarceration. Utilizing the Preferred Reporting Items for Systematic Reviews and Meta‐Analysis, 19 out of 304 articles met the inclusion criteria for full review. Our findings highlight the limited empirical evidence on relational therapy interven …

21.08.2026journal-article

Journal of Occupational & Environmental Medicine

Mortality Patterns Among Utah Firefighters, 2001–2024: A Proportionate Mortality Study

Yanling Shi, Devinne Hart, Nicole Bissonette, Kyle Lunt, Xiaoming Sheng

Objective: Firefighters face exposures linked to chronic disease and suicide. This study evaluated cause-specific mortality among Utah firefighters versus other occupations. Methods: Utah death certificates (2001–2024) were analyzed using 2018 Census codes and NCHS causes. We estimated adjusted proportionate mortality odds ratios (aORs) for cancer, heart disease, diabetes, and suicide. Results: Analysis included 734 firefighter deaths and 366,952 others. After adjusting for demographics and tobacco use, firefighter …

21.08.2026journal-article

Neurosurgical Review

Intrathecal immune checkpoint inhibitors as adjunctive therapy for leptomeningeal disease: A case series and systematic review

Manav Daftari, Christian K. Ramsoomair, Anurag Aka, Vratko Himic, Anna Hudson, Manuela Aramburu Berckemeyer, Morgan Johnson, Victor M. Lu, Jay Chandar, Vaidya Govindrajan, Jose Lutzky, Michael E. Ivan, Ricardo J. Komotar, Ruham Nasany, Ashish H. Shah

Abstract Immune checkpoint inhibitors (ICIs) are promising for leptomeningeal disease (LMD), but systemic delivery is limited by poor cerebrospinal fluid penetration and treatment-related toxicity. This study evaluates the safety and efficacy of adjunctive intrathecal (IT) ICI therapy compared with systemic ICI alone. We report two institutional cases of melanoma-associated LMD treated with IT ICI alongside systemic therapy. Following PRISMA guidelines, PubMed, Embase, and Scopus were systematically reviewed, ident …

21.08.2026journal-article

EAS Journal of Orthopaedic and Physiotherapy

Functional Outcome of Open Latarjet Procedure for Recurrent Anterior Shoulder Instability with Hill-Sachs Lesion Following Sports Injury

Mohammad Lockman, Md. Zahir-Ul Islam, Mobinul Hoque, Muhammad Ariful Islam, Muhammad Rafiqul Islam, Suraiya Siddika, G.M. Jahangir Hossain

Background: The anatomical and biomechanical factors render shoulder joint the most unstable and frequently dislocated joint. Anterior instability is common and glenoidal bony defect result in recurrence. Effective surgical treatment is crucial to restore the normal functioning shoulder and return to the preinjury state The aims of this study were to assess the functional outcome of recurrent anterior shoulder instability with Hill-Sachs lesion following Latarjet procedure by ROWE score and report complications if …

21.08.2026journal-article

Frontiers in Cell and Developmental Biology

The role of molecular profiling for castration-resistant prostate cancer treatment and therapy development

Timothy J. Mann, Therese M. Becker, Tara L. Roberts, Paul de Souza, John G. Lock

Early-stage prostate cancer (PCa) is overwhelmingly driven by aberrant androgen receptor (AR) signalling. Accordingly, standard-of-care treatments include androgen deprivation therapy (ADT) and AR pathway inhibitors (ARPIs), with disease detection and therapy-response monitoring relying on blood-borne PSA, a product of AR transcriptional programs. Crucially, resistance to these therapies is inevitable but heterogeneous in nature; potentially driven by a diverse array of alternate signalling pathways and differentia …