International Journal of Contemporary Pediatrics
Balanced crystalloids versus normal saline for fluid therapy in pediatrics diabetic ketoacidosis: a systematic review
Fluid therapy is a cornerstone of management in paediatric diabetic ketoacidosis (DKA). Although normal saline has traditionally been the preferred resuscitation fluid, concerns regarding hyperchloremic metabolic acidosis have led to increasing interest in balanced crystalloids such as Ringer’s lactate and Plasma-lyte. However, evidence regarding their efficacy and safety in children with DKA remains limited and has not been comprehensively synthesized. A systematic review of the literature was conducted to evaluat …