Frag' FlorenceEvidenz. Klar. Anwendbar.
Uhr 7/8Sources Journal Tree
Easy Demo

Florence Themenbrowser · Medizin · Seite 44

Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

Themen erkunden

Aktuelle Forschung nach Fachgebiet

24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
27.08.2026journal-article

Visualization in Medicine

Галерея истории лучевой диагностики

Татьяна Николаевна Трофимова, Наталия Александровна Карлова, Марина Геннадьевна Бойцова, Ярослав Петрович Зорин, Ирина Григорьевна Камышанская

Первая в мире виртуальная Галерея истории лучевой диагностики открылась в октябре 2025 г. в Санкт-Петербургском государственном университете (СПбГУ). Мультимедийный ресурс посвящен развитию рентгенологии в России и охватывает все направления лучевой визуализации от момента открытия рентгеновского излучения до наших дней. В основу виртуальной Галереи истории лучевой диагностики была положена концепция сохранения исторических материалов, фотографий, воспоминаний врачей, ученых, персонала отделений лучевой диагностики …

27.08.2026journal-article

Clinical Journal of Health Sciences

The Role of Anima-Animus Balance in Relationships and Its Psychopathological Reflections: A Review within the Framework of Analytical and Clinical Psychology

Gamze Küçükaslan, Reşat Güven, Buse Odabaşı, Deniz Ergün

This study is a systematic review examining the role of anima and animus archetypes in the spiritual integration processes of individuals, their effects on interpersonal relationships, and their psychopathological manifestations within the framework of Carl Gustav Jung’s analytical psychology theory. Anima and animus are defined as opposite-sex archetypes located in the unconscious of the individual and play a decisive role in the individuation process. In this context, the effects of anima and animus on the indivi …

27.08.2026journal-article

Medical Sciences

Clinical Remission Trajectories Beyond 12 Months in Severe Asthma Patients Continuing a Single Biologic: A Real-World Single SANI Center Cohort

Simone Negrini, Stefania Nicola, Francesco Sardanapoli, Rocco Francesco Rinaldo, Marco Russo, Iuliana Badiu, Anna Quinternetto, Luca Lo Sardo, Francesco Blasi, Pierluigi Paggiaro, Enrico Heffler, Giovanni Rolla, Caterina Bucca, Giorgio Walter Canonica, Fulvia Ribolla, Paolo Solidoro, Luisa Brussino

Background: Clinical remission is an emerging therapeutic goal in severe asthma treated with biologics. However, remission may evolve beyond the conventional 12-month assessment, and limited real-world data are available on patients who continue the same biologic after incomplete remission at 12 months. We evaluated longitudinal remission trajectories in patients with severe T2-high asthma continuing the same biologic therapy. Methods: This retrospective real-world single-center SANI cohort included adults with sev …

27.08.2026journal-article

Archiv Euromedica

SOCIAL MEDIA AND MENTAL HEALTH SELF-DIAGNOSIS: RISKS, BENEFITS, AND CLINICAL IMPLICATIONS FOR ADOLESCENTS AND YOUNG PEOPLE

Bogna Błachowska, Wojciech Frączyk, Agata Świątek, Kamil Andruszkiewicz, Bartosz Machnio, Natalia Jasińska, Mateusz Krysiak, Natalia Turzyńska, Katarzyna Mania, Julia Bąk, Agnieszka Stankowska

Background Adolescents increasingly use social media platforms, including TikTok, Instagram, and Reddit, to obtain information about mental health and psychiatric disorders. Such content may facilitate mental health literacy, validation, and help seeking, but may also expose users to misinformation, oversimplified diagnostic narratives, and algorithmically reinforced content. Aim To examine the potential benefits and risks of mental health self-diagnosis through social media among adolescents and young people, with …

27.08.2026journal-article

Journal of Medical Internet Research

Stigmatizing Language in Gender-Expansive Patient Records: Corpus Development, Disparity Analysis, and Natural Language Processing–Based Detection Study

Liyang Xue, Mary Chayko, Vivek Kumar Singh

Background Stigmatizing language (SL) in electronic health records (EHRs) can influence clinical decision-making, propagate bias across care encounters, and undermine patient trust. Gender-expansive patients (GEPs) may be particularly vulnerable to documentation-based stigma; however, large-scale quantitative evidence and fairness-aware evaluation of automated SL detection methods remain limited. Objective This study aims to construct a gender-expansive-inclusive EHR corpus, quantify demographic disparities in SL u …

27.08.2026journal-article

International Journal of Sports Medicine

Post-Exercise Circulatory Occlusion Differently Affects Soleus Spinal/Supraspinal Excitability

André D. Gonçalves, Andréia Terra, Rodrigo Marques, Pedro Pezarat-Correia, Carolina Vila-Chã, Goncalo V Mendonca

Abstract Post-exercise circulatory occlusion allows the investigation of the effects of group III/IV muscle afferent feedback on central nervous system responsiveness. This study explored the effects of post-exercise circulatory occlusion on soleus H- and V-wave excitability. Following a randomized-crossover design, in 1 day, 16 healthy men (24.6±3.5 y) completed a 3-minute sustained plantar-flexion contraction at 40% of maximal voluntary isometric contraction. Then, for testing, a cuff was inflated around the ipsi …

27.08.2026journal-article

Frontiers in Medicine

Treatment and clinical outcomes among stage II–IVA nasopharyngeal carcinoma patients with undetectable pretreatment Epstein-Barr viral DNA

Ci-ming Sun, Zhen Xu, Cheng-hao Li, Jun-xiang Chen, Xin-yi Su, Jing-xia Song, Shuang-hong Song, Qing-qing Xu, Yan-Ling Wu

Background This study analyzed the efficacy of multiple combined chemotherapy modalities on the long-term survival outcomes in stage II–IVA nasopharyngeal carcinoma (NPC) patients with undetectable pretreatment Epstein-Barr viral DNA (pre-DNA). Patients and methods We retrospectively analyzed 2,440 patients with stage II–IVA NPC with undetectable pre-DNA. Patients received any of the following treatment modalities: intensity-modulated radiotherapy (IMRT) alone; concurrent chemoradiotherapy (CCRT); induction chemoth …

27.08.2026journal-article

Basic & Clinical Pharmacology & Toxicology

Plant‐Derived Heterocyclic Compounds: A Promising Review on Natural Remedies for Rheumatoid Arthritis Management and Their Mechanistic Insights in Inflammation and Joint Protection

Jindong Dai, Xue Xia, Xincheng Hu, Thangamani Kanagaraj, Kanagaraj Rajalakshmi, Mangirish Deshpande, Natarajan Kiruthiga, Dongwei Zhu, Yisun Fan

ABSTRACT Rheumatoid arthritis (RA) represents a persistent autoimmune disease that causes continuous joint inflammation and results in synovial tissue overgrowth and worsening cartilage breakdown together with degeneration of bones. The existing pharmaceutical treatments provide symptom management although they create important adverse effects and raise ongoing security concerns. Plant‐derived heterocyclic compounds present themselves as promising pharmaceutical substitution options because they demonstrate a wide …

27.08.2026journal-article

Magnetic Resonance Materials in Physics, Biology and Medicine

Recent advances in arterial spin labeling MRI for imaging brain tumors

Gabriel Hoffmann, Matthias J. P. van Osch

Abstract Perfusion MRI plays an important role in brain tumor assessment, especially for tumor grading and differentiation of tumor progression from pseudoprogression. Arterial spin labeling (ASL) MRI is a non-invasive method for measuring cerebral blood flow (CBF) using blood water as an endogenous tracer, which has great clinical potential for brain tumor imaging and might help to lower the use of gadolinium-based contrast agents. In this review, we discuss recent advances of the ASL method with a special focus o …

27.08.2026journal-article

Journal of Applied Clinical Medical Physics

Fast fourier transform based spectral features for machine learning prediction of gamma passing rates in virtual VMAT PSQA: A feasibility study

Bing Yan, Hu Peng, Xudong Xue, Chichao Zheng, Aidong Wu

Abstract Purpose This study aimed to evaluate the feasibility of fast Fourier transform (FFT) based spectral features for predicting volumetric modulated arc therapy (VMAT) gamma passing rates (GPRs) in virtual patient‐specific quality assurance (PSQA). Methods A total of 481 VMAT treatment plans were retrospectively collected. Multileaf collimator (MLC) trajectories and monitor units (MU) were extracted from control points (CPs) and interpolated onto a uniform gantry‐angle grid. FFT‐based power spectra were then c …

27.08.2026journal-article

World Journal of Gastrointestinal Surgery

Refined endoscopic technique combined with cold forceps polypectomy for diminutive colorectal polyps

Xue-Man Wang, Qin-Wei Xu, Yu-Zhen Bi, Quan Luo, Bo Lian, Jian Dong, Xin-Tong Jiang, Jun Zhang

BACKGROUND The most appropriate endoscopic management for small (≤ 5 mm) colorectal adenomas has not yet been well established. Although cold snare polypectomy (CSP) is recommended by the guidelines, cold forceps polypectomy (CFP) remains a popular technique because it is easy to perform. However, previous data have suggested that a modified CFP technique using jumbo biopsy forceps, post-resection narrow-band imaging (NBI), and submucosal injection can yield high en bloc resection rates. AIM To assess the performan …

27.08.2026journal-article

World Journal of Gastrointestinal Surgery

Endoscopic management of common bile duct stump fistula after choledochojejunostomy: A case report

Wen-Fei Wang, Zhen-Yu Qiao, Zhuang Li, Ke-Zhong Zheng, Deng-Qun Sun, Ming-Hui Sheng

BACKGROUND Common bile duct (CBD) stump fistula after choledochojejunostomy is an exceedingly rare phenomenon. We report a unique case suffering from pancreaticobiliary reflux. CASE SUMMARY A 73-year-old man underwent Roux-en-Y end-to-side choledochojejunostomy for recurrent CBD stones. Fourteen days after surgery, the patient presented with high-amylase bile drainage (3192 U/L). Imaging revealed a CBD stump fistula. Endoscopic retrograde cholangiopancreatography showed pancreaticobiliary maljunction and sphincter …

27.08.2026journal-article

Revista ft

Capacitação da equipe de clínica médica quanto às atualizações do manejo agudo hospitalar de fibrilação atrial de alta resposta ventricular

Victor Souza Nobre, Marilia Mendes de Saboya, Felipe de Araújo Lucena, Camila Amora Santos Albuquerque D’Alva, Natália Marinho Porto Lima, Luiza Targino Studart, José de Ribamar Barroso Jucá Neto

Atrial fibrillation with rapid ventricular response is a common condition in the hospital setting and requires prompt recognition, assessment of hemodynamic stability, and evidence-based therapeutic decision-making. Given the variability in clinical management and the need for professional updating, this study aims to train the Internal Medicine medical team on current recommendations for the acute hospital management of atrial fibrillation with rapid ventricular response, with the goal of standardizing clinical pr …

27.08.2026journal-article

Physics in Medicine & Biology

MGTP-Seg: A Mask Guidance and Text Prompting Network for Gross Tumor Volume Segmentation in Esophageal Cancer Radiotherapy

Chengwei Chen, Hongfei Sun, Yuxuan Yao, Yao Zheng, Yuefei Feng, Qifeng Wang, Wencheng Zhang, Yang Liu, Lina Zhao, Dong Huang

Abstract Accurate delineation of the gross tumor volume (GTV) is critical for determining the efficacy of radiotherapy in esophageal cancer. Conventional segmentation methods either rely solely on end-to-end learning from imaging features, which often struggle to address small tumor volumes and ambiguous boundaries, or incorporate coarse masks as spatial priors but fail to integrate the pathological semantics essential for clinical decision-making. This disconnect can lead to segmentation results that are poorly al …

27.08.2026journal-article

Developmental Medicine & Child Neurology

Deep brain stimulation outcomes and management of childhood‐onset dystonia and associated hyperkinetic movements disorders

Sinead Barkey, Laura Ainaga, Eva Maria Navarrete Muñoz, Verity McClelland, Keyoumars Ashkan, Richard Selway, Harutomo Hasegawa, Daniel E Lumsden, Jean‐Pierre Lin, Hortensia Gimeno

Abstract Aim To examine longitudinal changes in self‐selected goals and dystonia severity over 1 year, 2 years, and 5 years after deep brain stimulation (DBS) in children and young people (CYP) with dystonia and other hyperkinetic movement disorders, using CYP and caregiver reports. Method The retrospective cohort study included follow‐up to 5 years after DBS, with the number of participants varying across time points. In the CYP group, 62 participants were included at the 1‐year follow‐up, 50 at 2 years, and 17 at …

27.08.2026journal-article

JAMA Network Open

A Multilevel Intervention to Identify Individuals for Genetic Testing and Treatment

Kirsten A. Jorgensen, Nuria Agusti, Tara Coffin, Karla Barajas, Maria D. Iniesta, Erica M. Bednar, Alexa Kanbergs, Roni Nitecki Wilke, Isabel Beshar, Sara Pirzadeh-Miller, Sayoni Lahiri, Kathy Pratt, Kristofer Jennings, Heidy Bosch, Charles A. Leath, Beth Karlan, Melissa Frey, Ravi Sharaf, Karen Lu, J. Alejandro Rauh-Hain

Importance Cascade genetic testing (CGT) is a key strategy for cancer prevention in families with hereditary breast and ovarian cancer syndrome (HBOC) and Lynch syndrome (LS), yet uptake among at-risk relatives remains persistently low, particularly in medically underserved populations where structural and informational barriers limit access to genetic services. Objective To evaluate the feasibility and preliminary effects of IGNITE-TX (Identifying Individuals for Genetic Testing and Treatment), a scalable, bilingu …

27.08.2026journal-article

Clinical and Translational Gastroenterology

Diagnostic Performance of Six Tests for Helicobacter pylori Infection in Peptic Ulcer Bleeding: A Prospective Head-to-Head Comparison

Tanawat Geeratragool, Thanapat Atthakitmongkol, Supathep Tansirichaiya, Pubet Weeranawin, Somchai Leelakusolvong, Monthira Maneerattanaporn

Background: Rapid urease test (RUT) is widely used for diagnosing Helicobacter pylori (HP) because it is inexpensive and practical. However, its accuracy is reduced in peptic ulcer bleeding (PUB). We prospectively performed a head-to-head comparison of diagnostic tests in the same patients to evaluate their performance in this setting. Methods: After endoscopic hemostasis, gastric biopsies were obtained for RUT, histology, and PCR. Blood samples were collected for current infection marker (CIM) and anti-urease anti …

27.08.2026journal-article

Arthroscopy, Sports Medicine, and Rehabilitation

Availability and Pricing of Orthobiologic Knee Injections Vary by Practice Type but Not by Community Socioeconomic Vulnerability in Suburban New York

Tracy M. Tauro, Benjamin Hershfeld, Katharine Chen, Ran Lampert, Adam D. Bitterman, Randy M. Cohn, Nicholas A. Sgaglione

Purpose To assess the availability, price transparency, and pricing of platelet‐rich plasma (PRP), bone marrow aspirate concentration, and stem cell injections for knee osteoarthritis (OA) among orthopaedic sports medicine (OSM) practices and alternative clinics in suburban New York and to evaluate the impact of the economic status of a population on the availability and pricing of biologic injections. Methods Between July and September 2025, OSM practices and alternative clinics offering PRP, bone marrow aspirate …

27.08.2026journal-article

World Journal of Otorhinolaryngology - Head and Neck Surgery

Safety, Efficacy, and Mechanism of Action of Budesonide in Rhinitis and Rhinosinusitis: A Systematic Review

David W. Kennedy, Lei Cheng, De‐Yun Wang

ABSTRACT Objective Budesonide is a corticosteroid with unique pharmacokinetic and pharmacodynamic properties that has been a frontline treatment for patients with allergic rhinitis (AR) and chronic rhinosinusitis (CRS) since the 1990s. As research on budesonide continues to produce new insights, our aim was to synthesize recent investigations and provide up‐to‐date information on safety, clinical, and mechanism of action (MOA) outcomes. Data Sources Searches were restricted to PubMed from 2014/01/01 to 2025/02/26. …

27.08.2026journal-article

Neuro-Oncology

98 Barriers and opportunities in the integrated histopathological-molecular diagnosis of adult diffuse gliomas: a national survey of neuropathology units in UK&I

Vassili Crispi, Ute Pohl, Federico Roncaroli, Kathereena Kurian, Ashiward Merve, Peter Auguste, Arabella Scantlebury, Colin Watts, Victoria Wykes

Abstract Introduction Integrated histopathological–molecular diagnosis is central to the contemporary classification and management of adult diffuse gliomas. The delivery of timely integrated diagnosis remains operationally complex, resource-intensive, and variably implemented across healthcare systems. Methods We conducted an online cross-sectional national survey of all 23 neuropathology units covering 34 adult neurosurgical units across the United Kingdom and Ireland to characterise current diagnostic pathways f …

27.08.2026journal-article

Clinical Journal of Health Sciences

Investigation of the Relationship Between Psychopathological Symptoms, Acculturation, and University Adjustment Among Students from Eastern and Western Türkiye Studying in the TRNC

Merve Nehir Kurt, Mehmet Çakıcı, Atakan Taşkıran

The aim of this study was to compare the acculturation attitudes, university adjustment levels, and psychopathological symptoms of university students from the eastern and western regions of Türkiye studying in the Turkish Republic of Northern Cyprus (TRNC), and to examine the relationships among these variables. This descriptive cross-sectional study included a total of 100 university students enrolled at Near East University, comprising 50 students from the eastern regions and 50 students from the western regions …

27.08.2026journal-article

Tijdschrift voor Urologie

Klinische kenmerken en chirurgische behandeling van urogenitale endometriose: een retrospectief cohortonderzoek

Hanzhe Dong, Eefje Oude Lohuis, Johanna M. A de Bruin, Bob Theodoor Merks

Samenvatting Endometriose kan verscheidene orgaansystemen aantasten. Urogenitale endometriose (UGE) is een zeldzame vorm van diepe endometriose met betrokkenheid van blaas en/of ureters. In dit retrospectieve cohortonderzoek werden 80 vrouwen met UGE geïdentificeerd onder 1.568 geopereerde patiënten met diepe endometriose (2018–2024), overeenkomend met een prevalentie van 5,1 %. Blaasendometriose kwam voor bij 34 patiënten, ureterbetrokkenheid bij 32 en gecombineerde ziekte bij 14. Dysurie trad vaker op bij blaasbe …

27.08.2026journal-article

Frontiers in Medicine

Day-4 antipseudomonal and anti-MRSA de-escalation was not associated with higher mortality in critically ill patients with sepsis

Yuhang Zhang, Guoying Liao, Jianli Song, Yinsheng Liao, Lulu Zhang

Background Broad empiric antibiotics are often appropriate at the start of intensive care unit (ICU) sepsis care; however, continued antipseudomonal or anti-methicillin-resistant Staphylococcus aureus (MRSA) coverage may no longer be justified by the day-4 reassessment. We examined antibiotic de-escalation at this clinical decision point. Materials and methods We emulated two parallel target trials in Medical Information Mart for Intensive Care IV (MIMIC-IV) v3.1 and conducted a supportive multicenter analysis in t …

27.08.2026journal-article

Recycling

Life Cycle Assessment of Anaerobic Digestion Pathways for Winery Residues: Influence of Functional Unit Selection on Wastewater Treatment and Grape Pomace Valorization

Mara Silva, Vitor Coelho Barroso, José Pereira, Ana Catarina Faria

Winery activities generate large amounts of residues requiring sustainable management. Anaerobic digestion offers opportunities for resource recovery while reducing the environmental burdens associated with these residues. This study presents a gate-to-gate Life Cycle Assessment (LCA) of two anaerobic digestion pathways: winery wastewater treatment (Scenario A) and grape pomace valorization (Scenario B). Inventory data were obtained from pilot-scale operation and complemented with the Ecoinvent 3.10 database. Envir …