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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
27.08.2026journal-article

Otolaryngology–Head and Neck Surgery

Intraoperative PTH Monitoring in Primary Hyperparathyroidism: A Risk‐Stratified Approach

Sholem Hack, David Z Allen, Eric Remer, Eran E Alon, Gianna L Rosamilia, Ugur Nur Basmaci, Ron J Karni

Abstract Objective To evaluate whether routine intraoperative parathyroid hormone (ioPTH) monitoring is necessary in all cases of sporadic primary hyperparathyroidism (pHPT) in the era of advanced preoperative localization and to propose a conservative, risk‐stratified operative framework. Data Sources PubMed, Scopus, and Embase were searched for English‐language publications from January 2020 through January 2026, supplemented by key guidelines, consensus statements, and high‐impact reviews. Review Methods This na …

27.08.2026journal-article

Indian Journal of Plastic Surgery

The Use of Reverse Flow Free Radial Forearm Flap in Head and Neck Reconstruction

Gautam Biswas, Karnav Bharat Panchal

Abstract The free radial forearm flap (RAFF) is one of the most common flaps used in head and neck reconstruction. Exposure of tendons, limited skin volume, and graft loss are its known drawbacks. The reverse flow RAFF (RF-RAFF) where the skin island is designed over the proximal forearm offers many advantages over the conventional radial forearm free flap. A larger volume of skin is available with the bed being covered with muscle suitable for split-thickness skin graft. Though the use of RF pedicled RAFF is routi …

27.08.2026journal-article

Journal of Neurological Surgery Reports

Side-to-Side versus Traditional End-to-Side Approach to STA-MCA Bypass in Moyamoya Disease: A Comparative Meta-Analysis

David Cho, Gerardo Duran, Cory Greer, Abdurrahman F Kharbat, Michael Feldman, Andrew Bauer, Christopher Salvatore Graffeo

Background Superficial temporal artery to middle cerebral artery (STA-MCA) bypass is a standard-of-care treatment for adult patients with moyamoya disease (MMD). Although the classical technique is end-to-side (E-S) bypass, the side-to-side (S-S) construct has emerged as an alternative strategy with potentially reduced risk of postoperative cerebral hyperperfusion syndrome (CHS). Methods A PRISMA-compliant systematic review of MEDLINE and Embase databases was performed from inception to May 2026 identifying 72 stud …

27.08.2026journal-article

ANZ Journal of Surgery

Electric Scooter‐Related Deaths in Queensland, Australia

Nathan Milne, Jack Garland, Rexson Tse, Beng Beng Ong

ABSTRACT Background The use of electric scooters (e‐scooters) has become an increasingly common means of transport in various parts of the world, as an affordable form of short distance transport. However, there are associated problems related to limitations of pre‐existing infrastructure, legislative considerations, and injuries and deaths resulting from their use. There have been numerous studies regarding non‐fatal e‐scooter injuries, but few studies of fatalities. Methods This paper reviews all e‐scooter‐relate …

27.08.2026journal-article

Medicina

Predictors of Postoperative Morbidity in Hepatic Hemangioma Surgery: A Single-Center Experience

Ioana Teodora Ciortan (Popa), Catalin-Bogdan Satala, Robert Daniel Ciortan, Irina Balescu, Emanuela Sevastian, Raul Mihailov, Traian Dumitrascu, Nicolae Bacalbasa, Aurel Nechita, Irinel Popescu

Background and Objectives: Hepatic hemangioma is the most common benign liver tumor and is usually managed conservatively. When surgical treatment is indicated, accurate preoperative risk assessment is important because surgery is elective and aims to relieve symptoms while minimizing postoperative morbidity. This study aimed to identify preoperative predictors of postoperative morbidity following hepatic hemangioma resection. Materials and Methods: This retrospective cohort study included 274 consecutive patients …

27.08.2026journal-article

Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi

A Hybrid Approach to the Surgical Treatment of a Large Prolapsed Pedunculated Submucous (Nascent) Leiomyoma: Transvaginal Myomectomy Followed by Operative Hysteroscopy

Bekir Sıtkı İsenlik, Orkun Han, Zeynep Ozturk Inal, Hasan İnal

Uterine leiomyomas are the most common benign pelvic tumors in women. In rare cases, submucous leiomyomas may prolapse through the cervical canal into the vagina; these are referred to as nascent leiomyomas. The standard surgical treatment is transvaginal myomectomy, although hysteroscopic management may be required when complete removal of the pedicle base cannot be safely achieved by the vaginal route alone. We report the case of a 36-year-old nulligravid woman presenting with hypermenorrhea, pelvic pain, and fat …

27.08.2026journal-article

Gastric Cancer

Phase II study of mFOLFOX6 in advanced gastric cancer patients with severe peritoneal metastases (WJOG10517G), including an individual patient data comparison with JCOG1108/WJOG7312G

Toshiki Masuishi, Hiroki Hara, Takayuki Ando, Takeshi Kawakami, Yoshiyuki Yamamoto, Naotoshi Sugimoto, Kazuhiro Shiraishi, Taito Esaki, Yuji Negoro, Takao Tsuzuki, Hiroaki Sawai, Masato Nakamura, Takashi Inagaki, Yudai Shinohara, Kentaro Kawakami, Seiichiro Mitani, Kenji Tsuchihashi, Chihiro Kondoh, Hiroo Katsuya, Osamu Maeda, Yuriko Fujita, Kenichi Yoshimura, Masanori Terashima, Takako Eguchi Nakajima, Kei Muro

Abstract Background Advanced gastric cancer patients with severe peritoneal metastases, defined as massive ascites throughout the abdominal cavity and/or inadequate oral intake requiring intravenous infusion support, have been excluded from pivotal clinical trials. Methods This phase II trial evaluated mFOLFOX6 in HER2-negative, chemotherapy-naive advanced gastric cancer patients with severe peritoneal metastases. The primary endpoint was overall survival (OS); secondary endpoints included ascites response rate amo …

27.08.2026journal-article

Journal of Trauma Anaesthesia, Resuscitation and Critical Care

Airway Management in a Patient with Extensive Maxillofacial Trauma: A Case Report

S. Deepak Shanker, Abhishek Nagarajappa, Reshma Kalagara, Christopher Dass

Managing the airway in patients with severe maxillofacial trauma remains one of the most demanding challenges in trauma care. Facial fractures not only distort normal anatomy but can also lead to airway obstruction, bleeding, aspiration risk, and difficulty in ventilation and intubation. Effective airway management in these cases depends on rapid decision-making, readiness for alternative airway techniques, and close coordination between the anesthesiologist and surgeon. A well-planned, individualized approach is e …

27.08.2026journal-article

Journal of Clinical and Translational Research

Can hydrogen-rich water increase nitrite and nitric oxide in patients with central obesity?

Ram B. Singh, Monika Jankajova, Divyank Sharma, Sarthak Sharma, Mohammad Arif Niaz, Oleg Medvedev, Peter Stefanic, Alexander Tarnava, Duried Alwazeer, Emel Uçarer, Najah Hadi, Jagdish Prasad Sharma

Background: Inflammation and oxidative stress play important roles in the pathophysiology of cardiovascular diseases. Hydrogen therapy, due to its antioxidant activity, has become a supplementary treatment. Objective: This study aims to investigate whether hydrogen-rich water (HRW) affects nitrite levels, a precursor of nitric oxide. Methods: Of 71 patients who volunteered, only 60 were selected due to the presence of metabolic syndrome and were randomly divided into either an intervention (HRW; n = 30) or placebo …

27.08.2026journal-article

Arthritis & Rheumatology

Plasma proteome reflects tissue damage and clinical manifestations in patients with inflammatory myopathies

Yue‐Bei Luo, Josefin Kenrick, Angeles S Galindo‐Feria, Antonella Notarnicola, Ana Daniela Ulloa Navas, Irene Peralta‐Garcia, Orane Demuynck, Andrea Kemp, Valérie Leclair, Karin Lodin, Eveline Van Gompel, Lara Dani, Fabricio Espinosa‐Ortega, Maryam Dastmalchi, Leonid Padyukov, Charlotta Preger, María Bueno Álvez, Mathias Uhlén, Peter Nilsson, Fredrik Edfors, Lina‐Marcela Diaz‐Gallo, Elisa Pin, Ingrid E Lundberg, Begum Horuluoglu

Objective Tissue‐specific biomarkers that are reliable and associated with clinical manifestations of idiopathic inflammatory myopathy (IIM) are lacking. The blood circulation in individuals serves as a central conduit, allowing communication between tissues and facilitating clearance and recycling of tissue‐derived proteins. Thus, we applied a dual antibody‐based proximity extension assay to profile >1000 proteins in subtypes of patients with IIM. Methods Plasma samples from 201 patients diagnosed with IIM at Karo …

27.08.2026journal-article

International Journal of Economics and Financial Management

Diagnosis of Life and Non-Life Insurance Sector on Economic Growth in Nigeria: Impact and Feasibility

Sueneme Bobkime Ofoniofoni

The research focused its attention on life and non-life insurance activities independently regarding their economic impact in Nigeria from 1990 to 2024. The empirical study was conducted using descriptive statistics. The descriptive statistics indicate that both the dependent and independent variables exhibit a normal distribution, as evidenced by the Jarque-Bera probability value. The unit root analysis reveals that the series are integrated of order one (1), whereas the Johansen cointegration test confirms a long …

27.08.2026journal-article

Frontiers in Medicine

SOFA score in gas-forming pyogenic liver abscess: a case series of seven patients with exploratory analysis of severity and mortality

Ning-Bo Xiao, Xiao-dong Zhang, Ze Yu, Jin-Liang Dong

Gas-forming pyogenic liver abscess (GFPLA) is a rare and highly fatal subtype of bacterial liver abscess, closely related to diabetes and hypervirulent Klebsiella pneumoniae infection. This case series analyzed seven patients diagnosed with GFPLA by CT, aiming to explore their clinical characteristics and prognosis. Among the patients, four died, with a total mortality rate of 57.1%, significantly higher than the 27.7%−37.1% reported in the literature. The sequential organ failure assessment (SOFA) scores of the de …

27.08.2026journal-article

Bioinformatics

Finetuning Foundation Models for Temporal Clinical Transcriptomics Data

Sachin Mathur, Alexander Kagan, Peyman Passban, Hamid Mattoo, Euxhen Hasanaj, Ziv Bar-Joseph

Abstract Background Timeseries clinical transcriptomic datasets offer the opportunity to gain insights into the dynamics of disease mechanisms/treatment responses. However, their utility in uncovering temporal patterns is often limited by high noise levels and small sample sizes. Leveraging foundational gene embeddings and incorporating interaction information can help address these challenges, improve gene network analysis, and enable the detection of subtle changes that drive disease progression or drug response. …

27.08.2026journal-article

Life

Recent Advances in Biomarkers of Systemic Sclerosis-Associated Interstitial Lung Disease: Clinical Relevance and Therapeutic Perspectives

Rasha-Ioana Rămoiu-Shehada, Anca Emanuela Mușetescu, Lucian-Mihai Florescu, Alesandra Florescu, Paulina-Lucia Ciurea

Systemic sclerosis-associated interstitial lung disease (SSc-ILD) is the leading cause of mortality in patients with systemic sclerosis and a major clinical challenge due to its heterogeneous presentation and variable disease course. Reliable biomarkers may improve disease assessment, risk stratification, and therapeutic decision-making. This narrative review summarizes current evidence on established and emerging serum and molecular biomarkers in SSc-ILD and their potential clinical applications. Recent advances h …

27.08.2026journal-article

World Journal of Gastrointestinal Surgery

Effect of enhanced recovery after surgery-based early mobilization on gastrointestinal recovery after intestinal tuberculosis surgery

Xia-Nan Li, Cai-Xia Zhang, Qian He, Juan-Min Xue

BACKGROUND Intestinal tuberculosis is the most common form of abdominal tuberculosis, and surgical intervention is required when complications arise or conservative treatment fails. Postoperative gastrointestinal function recovery in these patients is often delayed, increasing complication rates and hospital stays. Early mobilization based on enhanced recovery after surgery (ERAS) principles has shown benefits in various gastrointestinal surgeries, yet its application in intestinal tuberculosis surgery remains insu …

27.08.2026journal-article

World Journal of Gastrointestinal Surgery

Transumbilical three-port vs conventional laparoscopic appendectomy: A single-center retrospective comparative study

Hai-Bo Yu, Yi-Bing Jin

BACKGROUND Laparoscopic appendectomy (LA) is a widely accepted treatment for acute appendicitis. Conventional three-port techniques require additional abdominal incisions that may affect cosmetic outcomes, whereas transumbilical approaches may improve scar concealment. However, direct comparative evidence remains limited. AIM To evaluate the safety and perioperative outcomes of transumbilical three-port LA compared with conventional LA. METHODS This retrospective single-center comparative study included 77 patients …

27.08.2026journal-article

Anaesthesiology Intensive Therapy

Disrupted thyroid hormone homeostasis in critical illness: clinical correlates and associations with hormone supplementation in a single-center retrospective observational study

Alicja Filipczyk, Szymon Zdanowski, Jan Kasprzyk, Karolina Niedzielska, Artur Rakhatsevich, Magdalena Anna Wujtewicz, Tomasz J. Stefaniak, Karol P. Steckiewicz

Background Thyroid hormone disturbances are a hallmark of critical illness and are commonly attributed to non-thyroidal illness syndrome. The clinical relevance of thyroid hormone supplementation in the intensive care unit (ICU) remains uncertain. This study aimed to characterize thyroid hormone concentrations in relation to disease severity in critically ill patients receiving thyroid hormone supplementation. Methods In this single-center retrospective study, data from 98 ICU patients receiving thyroid hormone sup …

27.08.2026journal-article

Frontiers in Oncology

Feasibility, reliability, and clinical value of genomic assay on pre-therapeutic biopsy for endocrine receptor-positive HER2-negative early breast cancer

Gilles Houvenaeghel, Maxime Souquet Bressand, Valérie Juhan Duguet, Monique Cohen, Catherine Bouteille, Laura Sabiani, Julien Barrou, Loic Juquel, Véronique Brunel, Olivia Quilichini

Endocrine receptor-positive (ER+) and HER2-negative breast cancer (BC) represents approximately 80% of all BCs. Most patients are treated with upfront surgery; however, 15%–30% will develop late recurrences. Genomic assay indication is usually based on postoperative pathological data including histology subtype, tumor size, lymph node status, SBR grade, and Ki67. Performing genomic testing on core needle biopsy specimens prior to surgery may offer several advantages. In this manuscript, we assess the feasibility, r …

27.08.2026journal-article

Clinical Journal of Health Sciences

Vaginismus and Dyspareunia: A Comparative Review of Female Sexual Pain Disorders

Melike Çarıkçı, Ayhan Çakıcı

Vaginismus and dyspareunia are among the most prevalent female sexual pain disorders and have a substantial impact on sexual functioning, psychological well-being, and intimate relationships. Although these disorders were historically classified as separate diagnostic entities, they were unified under the diagnosis of Genito-Pelvic Pain/Penetration Disorder (GPPPD) in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). Nevertheless, this diagnostic integration has generated ongoing deb …

27.08.2026journal-article

Clinics and Practice

Scientific Clinical Trial Publication Productivity in Medical Oncology: A Comparative Analysis and Data Review of Northern and Southern Italy

Vittorio Gebbia, Sergio Rizzo, Dario Piazza, Daniela Sambataro, Giuseppa Scandurra, Maria Rosaria Valerio

Background: Italy exhibits a socioeconomic divide between its northern and southern regions, which extends into healthcare delivery and biomedical research. Medical oncology is particularly affected by this structural imbalance. This paper examines geographic disparities in clinical trial scientific publication output, citation impact, research funding, and collaboration networks in medical oncology between northern and southern Italy. Methods: A narrative bibliometric analysis was conducted using data from PubMed …

27.08.2026journal-article

Clinical Psychology & Psychotherapy

Imagery Interventions and Cognitive‐Behavioural Therapy for Psychological Complaints Related to Bullying: A Systematic Review and Meta‐Analysis

Meng Liang, Gerly Tamm, Olivia De Laere, Yannick Vander Zwalmen, Ernst H. W. Koster

ABSTRACT Bullying is associated with internalizing symptoms and impaired everyday functioning. Cognitive‐behavioural therapy (CBT) and imagery interventions have been studied as treatments to improve mental health after such experiences. This meta‐analysis aimed to evaluate the effects of individual CBT and imagery interventions in targeting internalizing symptoms (negative affect, depression, anxiety and post‐traumatic stress symptoms) and improving self‐perception and coping in bullying victims. Systematic search …

27.08.2026journal-article

Journal of Intensive Care Medicine

Correlation Study Between Inflammatory Markers and Pathogenic Characteristics in Patients with Severe Pneumonia in Intensive Care Units

Xiufang Lu, Yali Kang, Lin Liu, Jingping Liu, Qiuyue Zhang, Jinjing Tian, Chuntang Tong

Objective To determine pathogen-specific inflammatory biomarker profiles, develop predictive models for Gram-negative infections and evaluate the added value of serial biomarker monitoring in critically ill patients with severe pneumonia in intensive care units (ICUs). Methods This retrospective cohort study included 126 adults admitted to a tertiary ICU between 1 June 2021 and 31 May 2024. Procalcitonin (PCT), C-reactive protein (CRP) and interleukin-6 (IL-6) were measured at admission and on ICU days 3, 5 and 7. …

27.08.2026journal-article

Crystals

A Review of Fatigue Performance Research on Aluminum Alloy Forming, Heat Treatment, Additive Manufacturing and Surface Modification Technologies

Baicheng Liu, Hongliang Zhang, Shenghan Li, Yurii Luhovskyi, Zhisheng Nong

Aluminum alloy is a lightweight, high-strength material based on aluminum matrix with the addition of elements such as copper, magnesium, silicon, zinc, manganese, or lithium. Featuring low density, high specific strength, excellent formability, and outstanding corrosion resistance, it is widely applied in the fields of aerospace, rail transit, automotive lightweighting, and additive manufacturing. In the aerospace sector, fatigue failure constitutes the primary failure mode of load-bearing components. This paper r …

27.08.2026journal-article

Frontiers in Medicine

Between scientific capital and emotional capital: a cross-sectional study on the empathetic clinical gaze in Swedish medical education

Lena Halawi, Atika Khalaf

Introduction Clinical empathy was examined among Swedish medical students to understand how empathic engagement evolves during training. The study explored both quantitative patterns and qualitative reflections related to the Empathetic Clinical Gaze (ECG). Methods Clinical empathy was examined using a cross-sectional quantitative survey of 251 Swedish medical students with the Empathetic Clinical Gaze scale (ECG scale). To contextualize the quantitative findings, a secondary qualitative content analysis of brief t …