Scientific Reports
Surgical resection and survival in second primary intrahepatic cholangiocarcinoma: a population-based cohort study
Abstract Second primary intrahepatic cholangiocarcinoma (SP-ICC) represents a growing clinical challenge in the era of improved cancer survivorship. The survival impact of formal surgical resection in this population remains unclear. This study aimed to evaluate the association between surgical resection and survival outcomes in patients with SP-ICC. We conducted a population-based cohort study using the Surveillance, Epidemiology, and End Results database (2000–2022). Patients with SP-ICC were stratified by cancer …