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Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
14.08.2026journal-article

Frontiers in Aging Neuroscience

Plasma α-synuclein and QSM-derived susceptibility in Parkinson’s disease: associations with clinical features

Xingjun Li, Tianfei Luo, Jing Bai

Background The pathological interplay between α-synuclein aggregation and iron dysregulation is central to the neurodegenerative process in Parkinson’s disease (PD). Quantitative susceptibility mapping (QSM) allows in vivo assessment of regional brain iron burden, and blood assays enable measurement of plasma α-synuclein; however, their clinical relevance and mutual relationship remain insufficiently defined. Objective To evaluate plasma α-synuclein as a diagnostic biomarker (against controls) and to explore whethe …

14.08.2026journal-article

Medicine

Vitamin D deficiency and dementia risk in patients with chronic kidney disease

I-Wen Chen, Li-Chen Chang, Yi-Chen Lai, Chun-Ning Ho, Jheng-Yan Wu, Kuo-Chuan Hung

Patients with chronic kidney disease (CKD) face elevated dementia risk, and vitamin D deficiency (VDD) has emerged as a potential contributor to cognitive decline. This study investigated the association between VDD and dementia development in patients with CKD using real-world data. We conducted a retrospective cohort study using the TriNetX database, analyzing patients with CKD aged ≥50 years from January 2010 to December 2022. Patients were stratified by serum 25-hydroxyvitamin D levels as follows: VDD group (<2 …

14.08.2026journal-article

International Journal of Environmental Research and Public Health

Association Between Changes in Perceived Neighborhood and Cognitive Performance Within Healthy Aging in Neighborhoods of Diversity Across the Life Span (HANDLS) Black Adults

Alexa C. Allan, Alyssa A. Gamaldo, Roland J. Thorpe, Jennifer D. Roberts, Michele K. Evans, Alan B. Zonderman

Perceived neighborhood characteristics are related to cognitive performance. However, limited studies have examined how changes in neighborhood characteristics relate to cognitive performance, particularly among Black adults who are likely to experience changes in their residential social and physical environments. This study examined the association between changes in perceived neighborhood quality and concurrent, cross-sectional cognitive performance. An analytic sample of 592 Black adults (Mage = 56.22; 58% fema …

14.08.2026journal-article

Prosthesis

How Well Do the Sample Populations in Microprocessor-Controlled Prosthetic Knee Technology Research Represent People with Limb Absence? A Systematic Review

Omar A. Alharbi, Alex Dickinson, Chantel Ostler, Maggie Donovan-Hall

Background/Objectives: Studies consistently demonstrate that microprocessor-controlled prosthetic knees (MPKs) improve mobility and quality of life for people with lower limb loss or absence by enhancing balance and reducing falls. However, the extent to which these benefits apply across demographic groups remains unclear. Therefore, we conducted a literature review to evaluate how representative and transferable research on MPKs is across different populations, and which factors influence this. Methods: Using syst …

14.08.2026journal-article

Online Brazilian Journal of Nursing

Associação entre sexo, grupos etários e cuidados com a saúde de pessoas idosas no Brasil

Emily da Silva Eberhardt, Eliane Pinheiro de Morais, Jack Roberto Silva Fhon, Idiane Rosset

Objective: To analyze the association between sex, age groups, and health care among older adults in Brazil in the years 2013 and 2019. Method: A cross-sectional study using public data from the National Health Survey (PNS), which included 11,177 people aged 60 years or older in 2013 and 22,728 in 2019. The Chi-square test was used for the association analysis according to sex and age groups (60 to 69 years, 70 to 79 years, and 80 years or older). Results: Blood pressure and blood glucose monitoring, as well as med …

13.08.2026journal-article

European Review of Aging and Physical Activity

Distribution of device-measured 24-hour movement behaviours across the cognitive spectrum in older adults: the HUNT study

Karen Sverdrup, Paul Jarle Mork, Eling D. de Bruin, Linda Ernstsen, Gill Livingston, Kushang V. Patel, Geir Selbæk, Bjørn Heine Strand, Beatrix Vereijken, Gro Gujord Tangen

Abstract Background Key daily physical activities (e.g., standing and walking), postures (sitting and lying), and sleep constitute the 24-h day and have distinct health effects and functional implications. Traditionally studied separately, the distribution of these movement behaviours and sleep across the cognitive spectrum remains insufficiently characterised. We aimed to describe and compare the distribution of 24-h movement behaviours and sleep across the cognitive spectrum. Methods We analysed cross-sectional, …

13.08.2026journal-article

Frontiers in Cellular and Infection Microbiology

Probiotic supplementation as a nutritional strategy for the prevention and management of sarcopenia in older adults

De’en Wang, Wei Yang, Xiaofang Qin

Introduction Sarcopenia, defined as the loss of skeletal muscle mass, strength, and functional capacity over time, poses a significant health burden among older adults. A growing body of evidence indicates that the gut microbiota contributes to inflammation and metabolic regulation, mitochondrial function, and anabolic signaling, thereby shaping the gut–muscle axis. Probiotic supplementation has gained traction as a nutritional approach for the regulation of microbiome-derived metabolites. The present study aims to …

13.08.2026journal-article

Working with Older People

Enhancing acceptance of retirement villages in later life: a strategy-based dimensional analysis

Phui Fung Wong, Xin Yu Ling, Hong Kok Wang, Li Ping Yow, Pei Sin Lay

Purpose Population ageing is reshaping how older adults evaluate and make decisions about later-life living arrangements. Retirement villages (RVs) have emerged as a viable housing option that promotes independence, well-being and community engagement; however, their acceptance remains limited in many emerging ageing societies, particularly in developing countries where retirement living markets are constrained by financial, institutional and socio-cultural challenges. This study aims to examine strategies that enh …

13.08.2026journal-article

Revista de Neuro-Psiquiatría

Asociación entre las actividades de la vida diaria según el estatus de demencia en personas adultas mayores durante el aislamiento por COVID-19 en Lima: un análisis secundario

Pou K. Choy-Chura, Jorge L. Marin-Paredes, Yzavo S. Gutierrez-Campos, Katherine L. Marin-Pimentel, Fernando M. Runzer-Colmenares

Objetivo: Determinar la asociación entre las actividades básicas e instrumentales de la vida diaria según el estatus de demencia y problemas de memoria en adultos mayores durante el aislamiento por COVID-19 en Lima. Materiales y métodos: Análisis secundario, retrospectivo y de tipo cohorte. La población del estudio proviene del análisis secundario de la base de datos del estudio «Comprendiendo cómo el grado de fragilidad afectó a la evolución de COVID-19». Resultados: Se observó que la edad promedio de los adultos …

13.08.2026journal-article

Journal of Organizational Effectiveness: People and Performance

From goodwill to systems: HR professionals' perspectives on AI and neurodiverse workplace inclusion

Ichraq Fahim, Reda Tamanine, Fatima Elkansoussi, Asmae El Gharbaoui, Hasnaa Alami

Purpose This study explores how human resource (HR) professionals perceive the role of artificial intelligence (AI) in fostering workplace inclusivity for neurodiverse employees. It addresses the persistent gap between the neurodiversity paradigm, which reframes cognitive differences as strengths and organizational practices that remain fragmented, disclosure-dependent and inconsistently implemented. Design/methodology/approach A qualitative, exploratory approach was adopted using semi-structured interviews with 12 …

13.08.2026journal-article

The Journals of Gerontology, Series B: Psychological Sciences and Social Sciences

Examining loneliness and purpose in life as mediators between discrimination and changes in episodic memory in midlife and older adults

Heather R Farmer, Elizabeth Wroten, Logan Szelestei, Mina Sajjadi, Jeffrey E Stokes

Abstract Objectives Discrimination is a stressor associated with worse cognition, but the pathways underlying this association are unclear. Moreover, discrimination may lead to exclusion and a reduced sense of belonging, which could increase loneliness and reduce purpose in life. We assess whether loneliness and purpose in life are mediators in the relationship between discrimination and episodic memory over an 8-year span. Methods Data were drawn from 6,155 respondents aged 51+ in the Health and Retirement Study ( …

13.08.2026journal-article

Buildings

Beyond Diversity: Gender-Specific Associations Between Community Leisure Facilities, Social Networks, and Mental Health of Chinese Older Adults

Qi Yang

Background/Objectives: Empirical research exploring the linkages between community leisure facility diversity, distinct facility categories, and mental health outcomes among older populations remains scarce, especially regarding gender-specific variations. Methods: Grounded in social capital theory, this study establishes an analytical framework to unpack the underlying mechanisms of these relationships. Based on a sample of 10,270 adults aged 60 and older drawn from the 2023 CLASS, structural equation modeling is …

13.08.2026journal-article

Wellcome Open Research

What is the impact of metabolic dysfunction-associated steatotic liver disease (MASLD) on outcomes in people living with chronic hepatitis B (CHB)? An umbrella review protocol

Emily Martyn, Jessica Carter, Maeve Barlow, Flora Olcott, Indrajit Ghosh, Elizabeth Waddilove, Alejandro Arenas-Pinto, Richard Gilson, Stuart Flanagan, WD Francois Venter, Jennifer Manne-Goehler, Sally Hargreaves, Emmanouil Tsochatizis, Douglas MacDonald, Philippa C Matthews

Introduction An estimated 254 million people are living with chronic hepatitis B virus (CHB) and 1.6 billion with metabolic dysfunction-associated steatotic liver disease (MASLD) worldwide. CHB remains a major global health challenge, despite a robust vaccine and suppressive antiviral treatment, and MASLD prevalence is increasing in line with a rise in cardiometabolic risk factors, such as obesity and type 2 diabetes. Thus, understanding the impact of concurrent CHB and MASLD on liver health is important to inform …

13.08.2026journal-article

REMUNOM

A Vivência da Gestação e Parto para Familiares de Pessoas com Transtorno do Espectro Autista (TEA)

Thalita Oliveira Santos, Anaisa de Carvalho Ribeiro, Debora Cristina Ferreira Ribeiro, Leandro Saldanha Nunes Mouzinho

Autism Spectrum Disorder (ASD) may have particular implications for the experience of pregnancy and childbirth, especially regarding sensory sensitivity, communication, emotional regulation, and the need for predictability. This study aimed to understand the experience of pregnancy and childbirth from the perspective of family members of people with ASD. This was an exploratory and descriptive field study with a qualitative approach. The study corpus consisted of two family members of women with ASD and four mother …

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13.08.2026journal-article

Studia Humanitatis Journal

Accesibilidad digital y participación social de las personas con discapacidad

Manuel Hernández Pedreño, Antonia Sánchez Alcoba

La digitalización se ha consolidado como un componente estructural del Estado de Bienestar contemporáneo y constituye un recurso esencial para el acceso a derechos, servicios y participación social. No obstante, sus beneficios no se distribuyen de manera equitativa y ciertos colectivos continúan quedando al margen de las oportunidades digitales. Entre ellos, las personas con discapacidad representan uno de los colectivos más afectados, ya que afrontan barreras de acceso, uso y aprovechamiento tecnológico, especialm …

13.08.2026journal-article

American Journal of Health Promotion

Associations of Restorative Sleep With Subjective Well-Being, Self-Rated Health, and Positive Lifestyle Factors in Adults and Older Adults: Proposals for Sleep-Promoting Behaviors

Kaori Yamaoka, Taro Matsuki, Hideki Tanaka

Purpose This study examined associations between restorative sleep and subjective well-being, self-rated health, and positive lifestyle factors among community-dwelling adults (20-64 years) and older adults (≥65 years) in Japan, and identified sleep-promoting behaviors related to restorative sleep. Design Cross-sectional study. Setting Community-based survey in Japan. Sample Stratified random sample of 5000 residents aged ≥20 years in City B, Prefecture A; 2371 valid responses analyzed (47.4%). Intervention Not app …

13.08.2026journal-article

Kidney and Blood Pressure Research

Nutritional Status as Predictor for Mortality in Older Adults With Acute Kidney Injury

María G. Zavala-Cerna, Alma L. Guzmán-Gurrola, Gabriela Asencio-del Real, José A. Novoa-Burquez, Julio A. Díaz-Ramos, Gerardo Oliva-Armas, David Leal-Mora, Evelyn Yared Villanueva-Muñoz, Andrea Alejandra Sánchez-Soto, Urima Alejandra Castañeda-Lara, Aranza Gabriela Montoya-González, Jonathan S. Chávez-Iñiguez

Older adults (OA) exhibit the highest incidence of acute kidney injury (AKI), with outcomes influenced by comorbidities, frailty, and malnutrition. Nutritional status, a potentially modifiable factor, has not been extensively evaluated as a mortality predictor in hospitalized OA with AKI. Our purpose was to report on the mortality risk provided by the nutritional status, comorbidities, and biochemical parameters in OA with AKI. Methods: In this prospective cohort study (July 2024–July 2025) conducted at a tertiary …

13.08.2026journal-article

Social Psychological and Personality Science

The Counterfactual Detective: People Think About What Could Have Been to Uncover Past Events

Jordan Bauman, Hailey Pawsey, Stephanie Denison, Ori Friedman

We reveal a way that people use counterfactual thinking: They use it to infer motives and solve mysteries about what happened in the unseen past. In three preregistered experiments, participants (total N = 1,242) were asked to determine which of two competitors in a contest had sabotaged a third competitor. Participants often succeeded in identifying the culprit when counterfactual reasoning could be used to judge whether each suspect profited from the sabotage. Participants had more difficulty, though, when the my …

13.08.2026journal-article

AIDS

Longitudinal trends in copy-years viremia associated with mpox acquisition but not mpox severity in people with HIV

Lauren O’Connor, Anne Monroe, Yun Ji, Anuja Baskaran, Amanda D. Castel, Angelo Elmi

Objectives: High viral load and low CD4 + cell count may be associated with increased risk of mpox acquisition. However, prior studies have not evaluated whether longitudinal trends in HIV lab measures, measured as the slope over time, are associated with mpox acquisition or severe mpox. Therefore, we evaluated whether longitudinal trends in CD4 + cell count (cells/μl), viral load (copies/ml), and copy-years viremia (CYV) (copies × years/ml) were associated with increased risk of mpox acquisition. Design: We conduc …

13.08.2026journal-article

Journal of Alzheimer’s Disease

Development and validation of an amyloid PET dementia of the Alzheimer's type (DAT) score

Mitchell Edema, Karteek Popuri, Hyunwoo Lee, Lei Wang, Mirza Faisal Beg, Alzheimer's Disease Neuroimaging Initiative

Background Alzheimer's disease (AD) can be debilitating if left untreated, but its progression may be altered through early detection. Objective To develop and evaluate a convolutional neural network (CNN) for detecting AD from amyloid PET brain images and to investigate the regions contributing to model predictions. Methods A 3D CNN with residual connections was developed to classify amyloid PET brain volumes. Amyloid PET data were obtained from the Alzheimer's Disease Neuroimaging Initiative (ADNI), with approxim …

13.08.2026journal-article

International Journal of Corpus Linguistics

“There’s a lot more Chinese people”

Qiao Gan

Abstract The variable realisation of there + be +plural arguments (e.g. there’s a lot more Chinese people ) is well-documented across English varieties, but little research has examined its use among ethnic minorities or how intersecting social factors shape its variation. This study addresses these gaps, analysing 1,549 tokens from 206 Australians of Anglo, Italian, Greek, and Chinese backgrounds, recorded in the 1970s and 2010s. The study finds an apparent-time increase in there’s during the 1970s, led by teenage …

13.08.2026journal-article

Journal of Palliative Medicine

Place of Death in Canada: An Analysis of the Decedent Questionnaire of the Canadian Longitudinal Study on Aging

Philip St. John, Robert Tate, Scott Nowicki, Genevieve Thompson, Cara Brown, Kerstin Roger, Shahin Shoostari, Lauren E. Griffith

Background: Understanding the factors associated with the place of death is important for planning individual care and health care services. Objectives: To determine the place of death of community-living Canadians in a cohort study; and to investigate the factors associated with the location of death. Design: The Canadian Longitudinal Study on Aging (CLSA) is a prospective cohort study of aging which commenced in 2010, with a sample of 51,338 community-living participants aged 45–85. There were 1287 participants w …

13.08.2026journal-article

PLANTS, PEOPLE, PLANET

Accidental plant poisonings in France: Lessons from a decade of national toxicovigilance

Gaël Le Roux, Adrien Maillot, Sylvie Michel, Jérôme Langrand, Sébastien Larréché, Christine Tournoud, David Boels, Magali Labadie, Nicolas Delcourt, Nathalie Paret, Luc de Haro, Sandra Sinno‐Tellier

Social Impact Statement Accidental plant poisonings reveal how modern societies are losing everyday botanical knowledge once central to food and health safety. By analyzing a decade of French toxicovigilance data, this study shows that most severe cases arise from plant misidentification or misguided self‐medication. These findings highlight the urgent need to reconnect people with plants through education, cultural transmission, and collaboration between health professionals and botanists. Preserving ethnobotanica …

13.08.2026journal-article

Healthcare

Lower Daily Walking Volume and Less Walking at Intermediate and Higher Cadences in Older Women with Clinician-Diagnosed Major Depressive Disorder: An Exploratory Cross-Sectional Study

Jungeun Lee, Mansoo Ko

Background/Objectives: Late-life depression is associated with reduced physical activity, but evidence is limited regarding objectively measured weekday walking volume and cadence distribution in older women with clinician-diagnosed major depressive disorder (MDD). This exploratory study compared daily walking between an MDD group and an age-comparable comparison group and examined the post hoc within-sample discrimination of two cadence-based ratios. Methods: Forty women aged 60–93 years (mean age, 71.8 ± 9.7 year …