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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
29.08.2026journal-article

Journal of Neuro-Oncology

Radiological response of primary central nervous system lymphoma after corticosteroid therapy and its predictive value on overall survival: a multicenter study

Florian Scheichel, D. Pinggera, T. Rossmann, B. Popadic, S. Aspalter, V. Schön, A. Woehrer, M. M. Dorostkar, C. Dorfer, C. F. Freyschlag, F. Marhold

Abstract Background Primary Large-B-Cell Lymphoma of the CNS (PCNS-LBCL) is a rare, aggressive tumor often sensitive to corticosteroid therapy (CST). This multicenter study investigated the spectrum of radiological responses to routine CST and evaluated its impact on patient prognosis. Methods The researchers utilized a prospective cohort of 18 patients for volumetric MRI analysis and a combined prospective-retrospective cohort of 31 patients for 2D tumor analysis. Patients received CST post-biopsy, with follow-up …

29.08.2026journal-article

Pharmaceuticals

Dopaminergic Radiopharmaceutical Imaging in Parkinsonian Syndromes: From Molecular Targets to Clinical Decision-Making

Wael Jalloul, Cristina Mariana Uritu, Despina Jalloul, Vlad Ghizdovat, Andreia Vranceanu Ciobanu, Bogdan Ionel Tamba, Cipriana Stefanescu, Irena Cristina Grierosu

Parkinsonian syndromes comprise overlapping neurodegenerative and non-degenerative disorders, making aetiological diagnosis difficult, while existing procedural guidance does not fully integrate tracer-specific biology with clinical decision-making, multimodal strategies, and emerging quantitative and pathology-directed biomarkers. This review synthesises evidence on the molecular targets, radiopharmaceutical characteristics, biological interpretation, and clinical applications of dopaminergic single-photon emissio …

29.08.2026journal-article

Journal of Human Lactation

Exploring the Efficacy and Safety of a Nursing Gel Formulation in Pregnant and Lactating Women With Cracked and Painful Nipples: An Open-Label, Single-Arm Clinical Study

Trupti Patel, Ramesh Prajapati, Virendra Narkhede M., Rutu Bhimani, Tejas Vyas, Mrityunjay Tiwari

Background: Breastfeeding women often experience nipple pain, usually caused by incorrect newborn positioning in the first 10 days after childbirth. Aim: To explore the efficacy and safety of a novel gel-based formulation in healthy pregnant and lactating women with cracked and painful nipples. Method: Sixty participants were instructed to gently apply approximately 0.5 g of test product onto the nipples and surrounding area for 14 days (an open-label, single-arm study). Nipple pain, nipple skin physical parameters …

29.08.2026journal-article

Clocks & Sleep

Associations Between Sleep Quality, Mental Health, and Vitality in Professional Drivers: A Cross-Sectional Study

Gabriela Roxana Louisse Neacşu, Agripina Rașcu

Professional drivers are exposed to work conditions that may affect sleep quality. Although poor sleep quality has been associated with lower mental health (MH) and vitality (VT), its relationship with these outcomes in professional drivers remains unclear. This cross-sectional study examined the association between sleep quality and selected health-related quality-of-life (HRQoL) domains among 399 professional drivers. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI). At the same time, HR …

29.08.2026journal-article

Genes

Clinical Insights into RELA-Associated Disease: From Genotype to Phenotype and Exploring Treatment

Chun Pan, Cuifang Zheng, Yuhuan Wang, Jieru Shi, Lin Wang, Ying Huang

Background/Objectives: RELA encodes the p65 subunit of NF-κB and plays a critical role in immune regulation, epithelial protection, and anti-apoptotic signaling. Pathogenic RELA variants cause monogenic immune dysregulation with heterogeneous clinical manifestations. However, genotype–phenotype relationships and optimal treatment strategies remain incompletely defined. Methods: We conducted a comprehensive literature-based analysis of reported individuals with RELA variants and additionally described a family carry …

29.08.2026journal-article

Denta: Jurnal Kedokteran Gigi

Effect of Low-Level Laser Therapy on The Number of Lymphocytes in Oral Ulcer Healing of Immunosuppressed Rats

Reiska Kumala Bakti, Desiana Radithia, Nurina Febriyanti Ayuningtyas, Fatma Yasmin Mahdani, Ghinaya Shaliha Nursaida Nisa

Background: Glucocorticoid-induced immunosuppression disrupts cellular immune responses, including lymphocyte function, and delays oral traumatic ulcer healing. Low-Level Laser Therapy (LLLT) offers an alternative for healing traumatic oral ulcers in immunosuppressed patients. Objective: To analyze the effect of 650 nm LLLT on the number of lymphocytes in traumatic ulcer tissue of immunosuppressed Wistar rats. Materials and Methods: Experimental laboratory study with a randomized post-test-only control group design …

29.08.2026journal-article

West African Journal of Allied Health Sciences

Appraisal of Heavy Metals in Some Fruits Sold in Effurun Market

Matthew Eturhobore Adu, Maxwell Momah

Background: Heavy metal contamination of edible food has become rampant in our society and this has led to increase in the occurrence of terminal diseases in the society. Fruits are cultivated, harvested and sold without cooking thereby protecting the nutrients in them. Contamination of fruits by heavy metals have been reported in some parts of Nigeria. Aim: Hence, this study aims to appraise the heavy metals in some fruits sold in Effurun market. Methods: Five edible fruits of Orange (Citrus sinensis), Watermelon …

29.08.2026journal-article

BMC Oral Health

Oral health, oral follow-up and infectious risk management of rheumatoid arthritis patients on anti-TNF drugs: a survey of a French e-cohort

Loredana Radoi, Hubert Marotte, Adelyne Ruyssen-Witrand, Martin Soubrier, Sonia Trope, Naïma Hamamouche, Raphaele Seror, Marjolaine Gosset

Abstract Background As periodontitis is a recognized risk factor for rheumatoid arthritis (RA), it should be adequately treated before the initiation of biologic disease-modifying antirheumatic drugs (bDMARDs), along with any concomitant acute oral infection. bDMARDs remains a concern for patients, and can pose challenges for dentists, particularly regarding the management of invasive procedures. Our aim was to assess adherence to oral health recommendations, and perioperative management of invasive dental procedur …

29.08.2026journal-article

Eskisehir Medical Journal, Eskisehir City Hospital

EFFECTS OF CONSCIOUS CONNECTED BREATHING EXERCISES ON BURNOUT LEVELS, SELF-ESTEEM, AND SELF-COMPASSION AMONG FEMALE HEALTHCARE WORKERS

Gulsum Uysal, Gulhan Yuksel, Merthan Tunay, Azize Yilmaz Gumus

Introduction: Burnout is a public health issue due to its effects on patients and public funds. We aimed to determine the impact of breathing sessions on the levels of burnout, self-esteem, and self-compassion among healthcare workers. Methods: A total of 52 participants were enrolled. The Brief Resilience Scale (BRS), Maslach Burnout Inventory (MBI), Rosenberg Self-Esteem Scale (RSES), and Self-Compassion Scale (SCS) questionnaires were completed prior and after the breathing group sessions. The scores were analyz …

29.08.2026journal-article

Scientific Reports

Self-efficacy and antenatal depression mediate the relationship between third-trimester maternal health literacy and adverse pregnancy outcomes

Ling Zhang, Fengju Li, Ting Luo, Hong Yang, Guangxu Deng, Honghui Rong, Chuanfen Zheng, Lu Lu, Enyu Lei, Li Ren, Ji-an Chen

Abstract This study aims to investigate the mechanisms through which maternal health literacy (MHL) influences adverse pregnancy outcomes (APOs), and to examine the mediating roles of self-efficacy (SE) and pre-pregnancy depression (AD) within this relationship for the first time. This cross-sectional survey recruited 322 pregnant women in the third trimester using a two-stage sampling method. Standardized instruments were used to collect data, including the Edinburgh Postnatal Depression Scale (EPDS), the MHL ques …

29.08.2026journal-article

JAMA

Digital Outreach to Improve Statin Refills in Patients With Low Statin Adherence

Ankeet S. Bhatt, Vincent X. Liu, Baiyang Sun, Mirasol Apostol-Largeteau, Ben J. Marafino, Mariam Amiri, Duc (Lilly) Tran, Andrew P. Ambrosy, Howard H. Dinh, Lucy Finn, Payton Watt, Josephine Au, Jaya Nadella, Noreen Jesani, Jean C. Digitale, Tor Biering-Sørensen, Brian L. Claggett, Scott D. Solomon, Muthiah Vaduganathan, Alan S. Go, Ivy A. Ku, Gopi Manthripragada, Kevin Yee, Kristine Lee, Mehreen Khan, ADHERE-ASCVD Investigators, David Ouyang, Erin Wong, Julisa Carter, Gurjot Kaur, Marilena Newberry, Irina Komardenkova, Lindsey Burbage

Importance Statin nonadherence is a leading, addressable driver of preventable cardiovascular events. Although health systems routinely use outreach to promote preventive care, most strategies are static and lack evidence from randomized clinical trials. Objective To determine whether an adaptive, sequential digital outreach strategy improves short-term statin refill vs usual communication among adults with established atherosclerotic cardiovascular disease (ASCVD) or high ASCVD risk and recent nonadherence within …

29.08.2026journal-article

Journal of Life Science and Public Health

Integrated Behavioral-Health and Social-Needs Care Coordination Following Nonfatal Firearm Injury: A Critical Narrative Review and Framework for Longitudinal Recovery

Kassim Nimotalai Olusola, Deborah Ave Okon, Atoyebi Oluwapelumi Diadem

Survival after a nonfatal firearm injury does not mark the end of the health consequences of that injury. A substantial share of survivors experience persistent post-traumatic stress, depression, chronic pain, and disrupted housing, employment, and transportation, and these domains interact to shape recovery. This narrative review synthesizes evidence on behavioral-health and social-needs care following nonfatal firearm injury, critically examines why conventional post-trauma systems are structurally poorly suited …

29.08.2026journal-article

Homœopathic Links

Effectiveness of Individualized Homoeopathic Medicine in LM Potencies in Pediatric Patients: A Single-Group Pretest-Posttest Interventional Study

Vignesh Kumar S., Shishir Kumar Singh, K. Vijay Ananth, Rajib Purkait, Kumaravel V., Tapan Kumar Behera

Abstract Scabies or seven years itch is a parasitic infestation on skin, by itch mite Sarcoptes scabiei var. hominis. Approximately 30 crore people are annually affected worldwide. In India, the incidence ranges from 18 to 42% in rural and urban areas. This study attempts to know the response of pediatric scabies to individualized homoeopathic medicines by LM potencies. Patients satisfying the criteria for confirmed scabies and clinical scabies in the International Alliance for the Control of Scabies consensus (201 …

29.08.2026journal-article

Journal of Emergency Management

Developing and evaluating simulation-based pandemic preparedness training for prehospital emergency healthcare workers

Seval Çalışkan Pala, Selma Metintaş, Engin Özakın, Veli Görkem Pala

Objective: The primary objective of this study was to compare the effectiveness of computer-based simulation (CBS) and mannequin-based simulation (MBS) on post-training performance among prehospital emergency healthcare workers (PEHWs). Secondary objectives included evaluating within-group pre–post changes and assessing perceived training effectiveness. Methods: This quasi-experimental study was conducted in Türkiye between 2020 and 2021. After standardized online theoretical training, participants were allocated t …

29.08.2026journal-article

Experimental Physiology

Cardiometabolic effects of contrast therapy: A systematic review

Veerle de Haan, Guy Plasqui, Hannah Pallubinsky

Abstract The rising prevalence of overweight and obesity, together with associated cardiometabolic disorders, underscores the need for additional strategies alongside established interventions. The growing popularity of contrast therapy – alternating exposure to heat and cold, a practice common in traditional Finnish sauna bathing – has prompted interest in its potential cardiovascular and metabolic health benefits. This systematic review outlines the acute and chronic effects of contrast therapy on cardiometabolic …

29.08.2026journal-article

West African Journal of Allied Health Sciences

Hepatoprotective Efficacy of Residual Aqueous Fraction of <i>Bombax costatum</i> Pellegr. Et Vuillet (Bombacacae) Stem Bark Against Carbon Tetrachloride<sub> </sub>Induced A<b>cute Liver Toxicity in Mice</b>

Nuhu Mohammed, Umar Abdullahi, Ahmadu Saleh, Umar Bala Ningi, Muhammad Rabiu Hamza

Introduction: Hepatic disease still remains a major public health problem due to vulnerability of the liver to a variety of metabolic, circulatory, neoplastic, xenobiotic and microbial insults. Liver injury is accompanied with derangement of vital body functions, hence the need to search for efficacious hepatoprotective agents with minimal side effect. This study aimed to evaluate the hepatoprotective efficacy of aqueous fraction of B. costatum stem bark (AFB) against carbon tetrachloride (CCl4) induced acute liver …

29.08.2026journal-article

Translational Medicine

Algebra vitae: a manifesto for the new mathematics of biology

S. V. Kozyrev

This paper formulates the problem of developing a mathematical language intrinsically suited to the historicity and organized complexity of living systems. The challenge lies not in the insufficient expressive power of modern mathematics, but in its underlying ontological assumptions. The mathematical framework developed for describing inert physical systems encounters fundamental limitations when applied to living systems. Models formulated within this framework cannot adequately describe systems whose state space …

29.08.2026journal-article

Nutrients

Phase-Specific Nutritional Therapy in Critical Illness: When Protein May Help and When It May Harm, from Acute Metabolic Adaptation to Post-ICU Recovery

Mircea Stoian, Adina Stoian, Claudia Bănescu, Sergio Rares Bandilă, Alina Danilesco, Hajnal Finta, Leonard Azamfirei

Background: Nutritional support in critically ill patients remains one of the most debated aspects of intensive care medicine. Although international guidelines have long recomm.ended early nutritional support with progressive protein delivery, recent clinical evidence has questioned the benefit of aggressive early calorie and protein provision during the acute phase of critical illness, highlighting the need for phase-adapted nutritional strategies. Methods: This narrative review summarizes current evidence on ind …

29.08.2026journal-article

BMC Medicine

24h movement behaviours in university students compared to working age and older adults: wearable-based evidence and cardiometabolic health implications

Ju Lynn Ong, Shuo Qin, Tara H Martin, Xin Yu Chua, Chun Siong Soon, Gizem Yilmaz, Lieng Hsi Ling, Falk Müller-Riemenschneider, Woon-Puay Koh, Michael WL Chee

Abstract Background Physical inactivity, sedentary behaviour and inadequate sleep are established risk factors for non-communicable diseases. Although older adults are traditionally expected to be less active and more sedentary than young adults, contemporary social, occupational and educational environments may have changed this. Here, we characterised 24-hour movement behaviours (physical activity [PA], sedentary behaviour [SB], and sleep) across adulthood using wearable devices and examined their cardiometabolic …

29.08.2026journal-article

Journal of Pure and Applied Microbiology

Molecular Docking Analysis of Coumarin and Indole Derivatives Targeting the MexB and GyrB in Multidrug-resistant Pseudomonas aeruginosa Clinical Isolates

Hawraa Natiq Kabroot AL-Fatlawy

Multidrug-resistant (MDR) Pseudomonas aeruginosa has emerged as a significant clinical threat due to its high resistance to multiple antibiotic classes and the limited effectiveness of current therapeutic options. This study aimed to evaluate selected coumarin and indole derivatives targeting the MexB and GyrB proteins of MDR P. aeruginosa using an integrated in silico approach, supported by molecular characterization of clinical isolates. A total of 44 clinical P. aeruginosa isolates recovered from sputum, urine, …

29.08.2026journal-article

Indonesian Journal of Electronics, Electromedical Engineering, and Medical Informatics

An Explainable XGBoost Framework for Mortality Prediction in People Living with HIV Receiving Antiretroviral Therapy

Ni Putu Likayuni Viona, Ngakan Nyoman Kutha Krisnawijaya, Desak Nyoman Widyanthini

Mortality remains an important concern among people living with HIV (PLHIV) receiving antiretroviral therapy (ART), particularly when high-risk patients are not identified early. This study presents an explainable mortality prediction approach based on an optimized Extreme Gradient Boosting (XGBoost) classifier. A retrospective dataset containing 393 clinical records was analyzed. Before model training, duplicate entries were removed, missing values were imputed, categorical variables were encoded, and class imbala …

29.08.2026journal-article

Constellations

The Contested Grounds of Democracy's Noninstrumental Value: Deliberative Democracy Versus Public Equality

Vittorio Gerosa

ABSTRACT Disagreement about democracy's noninstrumental value often sees the opposition between two competing approaches. Liberty‐based arguments assign normative priority to a principle of liberty, thereby focusing on democratic self‐government as the core principle through which political authority can be reconciled with individual liberty. Equality‐based arguments fundamentally appeal to equality instead, thus commending democratic procedures for treating citizens as equals in the decision‐making process. This p …

29.08.2026journal-article

International "Journal of Academic Research for Humanities"

Informal Governance, Community Resilience, and the Making of Public Space

Masooma Mohib Shakir, Samia Sarfaraz

Public spaces in informally developed Global South settlements are frequently studied through a lens of deprivation and institutional neglect, yet research on community-managed public space in marginalized settlements remains limited. Actively used public spaces in such settlements offer critical insight into community-led spatial governance under minimal administrative control. This paper examines how community organization, cultural identity, historical attachment, informal governance, and spatial networks sustai …

29.08.2026journal-article

Journal of Immigrant and Minority Health

Are Group Interventions Effective at Improving Health Outcomes in Culturally And Linguistically Diverse (CALD) Populations With Chronic Conditions? An Umbrella Review

Karma Phuentsho, Emma L. Karran, Ruth P. Appiah, Marinelle Fernandez, Kristin Graham, Saravana Kumar, Saurab Sharma, Amanda C de C Williams, Aparnadas Amritha, G. Lorimer Moseley

Abstract Culturally and linguistically diverse (CALD) populations experience disproportionate burdens of chronic disease compared to the general population; previous research demonstrated group-based interventions improve health outcomes across various chronic conditions. This umbrella review aims to summarise the available evidence concerning group-based interventions for CALD populations with chronic conditions. We conducted this umbrella review in accordance with the Cochrane Handbook for Systematic Reviews of I …