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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
29.08.2026journal-article

Public Health Journal

Multivariate Analysis of Determinants of Mothers’ Willingness to Provide BCG Immunization to Children as an Effort to Prevent Tuberculosis in the Working Area of Paya Bakong Health Center

Mhd. Hidayatullah, Nurmakiah Nurmakiah, Rosalia Putri, Hafni Zahara

BCG immunization is one of the essential basic immunizations that provides protection against severe forms of tuberculosis in children. Mothers’ willingness to provide BCG immunization is an important aspect in achieving optimal immunization coverage. This study aimed to analyze the determinants associated with mothers’ willingness to provide BCG immunization in the working area of Paya Bakong Public Health Center. This study employed a quantitative analytical design with a cross-sectional approach. The study was c …

29.08.2026journal-article

Journal of the Pediatric Infectious Diseases Society

Corynebacterium urealyticum Urinary Tract Infections in Pediatric Renal Transplant Recipients: Clinical Spectrum and Management Strategies

Guyu Li, Alicia Morales, Elizabeth Ristagno, Anna Huppler, Nipunie Rajapakse

Abstract Background Pediatric renal transplant recipients are at increased risk for Corynebacterium urealyticum urinary tract infections (UTIs), which can range from simple nephritis to encrusted pyelitis and infected nephrolithiasis. Limited data exist regarding clinical spectrum and standardized management strategies, contributing to variability in treatment and prognosis. We describe two pediatric renal transplant recipients with C. urealyticum-associated encrusted pyelitis and infected nephrolithiasis and outli …

29.08.2026journal-article

Archiv Euromedica

SOTATERCEPT AS A POTENTIAL DISEASE-MODIFYING THERAPY IN PULMONARY ARTERIAL HYPERTENSION: A NARRATIVE REVIEW

Aleksandra Kamińska, Maria Miller, Aleksandra Pakulska, Aleksandra Błoch, Natalia Rządzińska

Background Pulmonary arterial hypertension (PAH) is a progressive and potentially fatal disease characterized by increased pulmonary vascular resistance, pulmonary vascular remodeling, and right ventricular failure. To date, therapy has relied mainly on vasodilatory action and has not sufficiently improved patients' long-term prognosis. There is therefore a need for therapies targeting pathways involved in disease progression and pulmonary vascular remodeling. Aims To summarize current data on the mechanism of acti …

29.08.2026journal-article

Journal of Nephrology

Burden of diagnosed and undetected hyperkalemia in Spain: Clinical characteristics, management, healthcare resource utilization, and costs

José Luis Gorriz, Roberto Alcázar, Patricia de Sequera, Enrique Morales, Miquel Blasco, Marco Montomoli, Alberto Ortiz

Abstract Background Management of hyperkalemia (HK) is challenging and suboptimal. This study analyzed the prevalence of HK and undetected HK, as well as management, clinical outcomes, healthcare resource utilization (HCRU), and costs. Methods Observational study comprising cross-sectional and retrospective analyses using secondary data from electronic health records (608,514 adults) from BIG-PAC database. The population comprised adults (n=7006) with a diagnostic code for HK, potassium >5.0 mmol/L and/or treatm …

29.08.2026journal-article

Journal of Clinical Psychology in Medical Settings

“I’m afraid to eat a piece of toast”: The Lived Experience of Balancing Eating and Health Behaviors in Adults with Chronic Pain

Lindsay Flegge, Susan Glassburn, Amanda Wakefield, Kristina Bogdan, Crystal Tracy, Michelle Miller

Abstract Chronic pain affects millions and is frequently comorbid with disordered eating behaviors; however, standard eating disorder screening tools often fail to capture the full scope of eating-related difficulties in this population. The purpose of this project was to explore the lived experience of eating problems among adults with complex chronic pain. Sixteen participants (15 women, age range 21–69, all White, non-Hispanic, cisgender) were interviewed by a member of the interprofessional research team, and d …

29.08.2026journal-article

Public Health Journal

The Effect Of Baby Massage On Weight Gain In Infants Aged 1-6 Months At The Sumartini Maternity And Child Health Clinic In 2026

Ika Wijaya, Nova Rati Lova, Maulida Lathifah

The 1- to 6 month age period is a phase of rapid growth for infants, making it necessary to monitor their weight changes regularly. Weight can serve as one parameter for assessing an infant’s growth and overall condition. Weight gain does not always proceed optimally for every infant, so stimulation is needed to support the growth process. One form of stimulation that can be applied to infants is baby massage. Massage through touch can help create a comfortable environment while supporting physiological processes r …

29.08.2026journal-article

Journal of Creative Power and Ambition (JCPA)

Design and Development of a Web-Based DMS for Community Health Center Accreditation and Self-Assessment Using Extreme Programming

Muhammad Jonni, Hengki Nurhuda

Accreditation document management is one of the essential components in supporting the accreditation process of Community Health Centers (Puskesmas). However, document management is still commonly performed manually using physical archives and digital files stored across multiple storage media. This condition leads to several issues, including difficulties in document retrieval, data duplication, lack of document version control, and the absence of integration between the self-assessment process and supporting accr …

29.08.2026journal-article

West African Journal of Allied Health Sciences

Predictors of Self-Reported Hearing Problems Among Commercial Transport Workers Using Personal Listening Devices in Kano State, Nigeria: A Cross-Sectional Study

Abbas Muhammad Sani, Mamuda Alhaji Sabo, Alhassan Muhammad Baba, Umar Shuaibu, Aisha Aliyu Ibrahim, Faiza Mukhtar Uba Abubakar, Shafa'atu Kani Fago, Saminu Zakari Chiroma, Adamu Alhaji, Sani Abdullahi Giade, Ibrahim Shehu Aliyu, Aisha Mahmoud Ibrahim

ABSTRACT Background Noise-induced hearing loss is one of the most common preventable occupational health problems worldwide. Commercial transport workers are routinely exposed to environmental and traffic noise and may experience additional auditory exposure through the use of personal listening devices. This study determined the prevalence of self-reported hearing problems and identified factors associated with hearing-related symptoms among commercial transport workers in Kano State, Nigeria. Methods A descriptiv …

29.08.2026journal-article

Current Neurovascular Research

Circadian Rhythm Disruption in Alzheimer’s Disease: Molecular Mechanisms, Clinical Implications, and Therapeutic Approaches

Romi Rajput, Anjali Sharma, Vishnu Mittal, Devkant Sharma

Introduction:: Alzheimer's Disease (AD) is a progressive neurological disorder characterized by unusual behavior, memory deterioration, and a decline in cognitive abilities. A growing body of research indicates that circadian rhythm disturbances play a crucial role in the pathophysiology of AD, impacting both molecular processes and clinical outcomes. This review critically evaluates the molecular interplay between circadian rhythm disruption and AD pathology, explores its impact on clinical manifestations and dise …

29.08.2026journal-article

BMC Oral Health

Oral health, oral follow-up and infectious risk management of rheumatoid arthritis patients on anti-TNF drugs: a survey of a French e-cohort

Loredana Radoi, Hubert Marotte, Adelyne Ruyssen-Witrand, Martin Soubrier, Sonia Trope, Naïma Hamamouche, Raphaele Seror, Marjolaine Gosset

Abstract Background As periodontitis is a recognized risk factor for rheumatoid arthritis (RA), it should be adequately treated before the initiation of biologic disease-modifying antirheumatic drugs (bDMARDs), along with any concomitant acute oral infection. bDMARDs remains a concern for patients, and can pose challenges for dentists, particularly regarding the management of invasive procedures. Our aim was to assess adherence to oral health recommendations, and perioperative management of invasive dental procedur …

29.08.2026journal-article

Scientific Reports

Self-efficacy and antenatal depression mediate the relationship between third-trimester maternal health literacy and adverse pregnancy outcomes

Ling Zhang, Fengju Li, Ting Luo, Hong Yang, Guangxu Deng, Honghui Rong, Chuanfen Zheng, Lu Lu, Enyu Lei, Li Ren, Ji-an Chen

Abstract This study aims to investigate the mechanisms through which maternal health literacy (MHL) influences adverse pregnancy outcomes (APOs), and to examine the mediating roles of self-efficacy (SE) and pre-pregnancy depression (AD) within this relationship for the first time. This cross-sectional survey recruited 322 pregnant women in the third trimester using a two-stage sampling method. Standardized instruments were used to collect data, including the Edinburgh Postnatal Depression Scale (EPDS), the MHL ques …

29.08.2026journal-article

JAMA

Digital Outreach to Improve Statin Refills in Patients With Low Statin Adherence

Ankeet S. Bhatt, Vincent X. Liu, Baiyang Sun, Mirasol Apostol-Largeteau, Ben J. Marafino, Mariam Amiri, Duc (Lilly) Tran, Andrew P. Ambrosy, Howard H. Dinh, Lucy Finn, Payton Watt, Josephine Au, Jaya Nadella, Noreen Jesani, Jean C. Digitale, Tor Biering-Sørensen, Brian L. Claggett, Scott D. Solomon, Muthiah Vaduganathan, Alan S. Go, Ivy A. Ku, Gopi Manthripragada, Kevin Yee, Kristine Lee, Mehreen Khan, ADHERE-ASCVD Investigators, David Ouyang, Erin Wong, Julisa Carter, Gurjot Kaur, Marilena Newberry, Irina Komardenkova, Lindsey Burbage

Importance Statin nonadherence is a leading, addressable driver of preventable cardiovascular events. Although health systems routinely use outreach to promote preventive care, most strategies are static and lack evidence from randomized clinical trials. Objective To determine whether an adaptive, sequential digital outreach strategy improves short-term statin refill vs usual communication among adults with established atherosclerotic cardiovascular disease (ASCVD) or high ASCVD risk and recent nonadherence within …

29.08.2026journal-article

Homœopathic Links

Effectiveness of Individualized Homoeopathic Medicine in LM Potencies in Pediatric Patients: A Single-Group Pretest-Posttest Interventional Study

Vignesh Kumar S., Shishir Kumar Singh, K. Vijay Ananth, Rajib Purkait, Kumaravel V., Tapan Kumar Behera

Abstract Scabies or seven years itch is a parasitic infestation on skin, by itch mite Sarcoptes scabiei var. hominis. Approximately 30 crore people are annually affected worldwide. In India, the incidence ranges from 18 to 42% in rural and urban areas. This study attempts to know the response of pediatric scabies to individualized homoeopathic medicines by LM potencies. Patients satisfying the criteria for confirmed scabies and clinical scabies in the International Alliance for the Control of Scabies consensus (201 …

29.08.2026journal-article

Journal of Neuro-Oncology

Radiological response of primary central nervous system lymphoma after corticosteroid therapy and its predictive value on overall survival: a multicenter study

Florian Scheichel, D. Pinggera, T. Rossmann, B. Popadic, S. Aspalter, V. Schön, A. Woehrer, M. M. Dorostkar, C. Dorfer, C. F. Freyschlag, F. Marhold

Abstract Background Primary Large-B-Cell Lymphoma of the CNS (PCNS-LBCL) is a rare, aggressive tumor often sensitive to corticosteroid therapy (CST). This multicenter study investigated the spectrum of radiological responses to routine CST and evaluated its impact on patient prognosis. Methods The researchers utilized a prospective cohort of 18 patients for volumetric MRI analysis and a combined prospective-retrospective cohort of 31 patients for 2D tumor analysis. Patients received CST post-biopsy, with follow-up …

29.08.2026journal-article

West African Journal of Allied Health Sciences

Appraisal of Heavy Metals in Some Fruits Sold in Effurun Market

Matthew Eturhobore Adu, Maxwell Momah

Background: Heavy metal contamination of edible food has become rampant in our society and this has led to increase in the occurrence of terminal diseases in the society. Fruits are cultivated, harvested and sold without cooking thereby protecting the nutrients in them. Contamination of fruits by heavy metals have been reported in some parts of Nigeria. Aim: Hence, this study aims to appraise the heavy metals in some fruits sold in Effurun market. Methods: Five edible fruits of Orange (Citrus sinensis), Watermelon …

29.08.2026journal-article

Journal of Life Science and Public Health

Integrated Behavioral-Health and Social-Needs Care Coordination Following Nonfatal Firearm Injury: A Critical Narrative Review and Framework for Longitudinal Recovery

Kassim Nimotalai Olusola, Deborah Ave Okon, Atoyebi Oluwapelumi Diadem

Survival after a nonfatal firearm injury does not mark the end of the health consequences of that injury. A substantial share of survivors experience persistent post-traumatic stress, depression, chronic pain, and disrupted housing, employment, and transportation, and these domains interact to shape recovery. This narrative review synthesizes evidence on behavioral-health and social-needs care following nonfatal firearm injury, critically examines why conventional post-trauma systems are structurally poorly suited …

29.08.2026journal-article

Journal of Neuropsychology

Enhancing social and linguistic skills in children with autism: A semi‐randomized controlled clinical trial of a virtual reality‐based communicative rehabilitation programme

Hassnaa O. Mohammed, Ehab M. Eid, Enas Rady Younes

Abstract Autism spectrum disorder (ASD) is characterized by persistent deficits in social communication, and conventional therapies often struggle to facilitate the generalization of these skills to real‐world settings. This study aimed to determine the effectiveness of a virtual reality (VR)‐based communication rehabilitation intervention as a supplement to conventional treatment for improving the linguistic and social communication skills of Arabic‐speaking Egyptian children with ASD. A clinical trial with a pret …

29.08.2026journal-article

Oral and Maxillofacial Surgery

Programmed Death-Ligand 1 (PD-L1) expression and clinical outcomes in oral squamous cell carcinoma: evidence from a large clinical cohort

Michael Alfertshofer, Maximilian Richter, Konrad Klinghammer, Christian Doll, Steffen Koerdt, Max Heiland, Friedrich Mrosk

Abstract Background Despite the recognized biological relevance of the PD-1/PD-L1 axis in immune evasion, the prognostic significance of PD-L1 expression in surgically treated oral squamous cell cancer (OSCC) patients remains largely unclear. Objective To investigate the prognostic significance of PD-L1 expression in a large cohort of OSCC patients primarily treated surgically in a single center. Methods This analysis included 156 consecutive OSCC patients treated with curative-intent surgery with their clinicopath …

29.08.2026journal-article

Journal of Clinical Immunology

NLRP1 Inflammasome is Associated to IL-18 in Familial Mediterranean Fever and MEFV Variants

Juan Miguel Suarez-Rivero, Inés Muela-Zarzuela, Daniel Boy-Ruiz, Raquel de la Varga-Martínez, Daniel García-Cuesta, Elisabet Alcocer-Gómez, Mario D. Cordero

Abstract “Familial Mediterranean Fever (FMF) (OMIM #249,100) is the most prevalent hereditary autoinflammatory disease globally, though it remains rare outside Mediterranean populations. FMF is caused by gain-of-function mutations in the MEFV gene, which encodes the immune regulatory protein pyrin. Recent studies suggest that multiple inflammasomes, including the pyrin inflammasome, may work synergistically to enhance their activity. In this study, we focused on NLRP1, and IL-18, an interleukin found at elevated le …

29.08.2026journal-article

British Journal of Clinical Pharmacology

Clinical relevance of pharmacogenomic information for improving prescribing practices in acutely admitted older medical patients

Louise Westberg Strejby Christensen, Anne Kirstine Boas, Emilie Clausen, Nicoline Elers Koch, Anne Byriel Walls, Lotte Stig Nørgaard, Michael Asger Andersen, Anissa Aharaz, Rikke Lundsgaard Nielsen, Olivia Bornæs, Juliette Tavenier, Baker Nawfal Jawad, Helle Gybel Juul‐Larsen, Esben Iversen, Ove Andersen, Lona Louring Christrup, Kim Peder Dalhoff, Morten Baltzer Houlind

Aims Safe prescribing and effective medication review during acute hospitalization depends on accurate information about liver and kidney function because these organs are responsible for the elimination of most medications. While estimates for kidney function are widely used, comparable markers of hepatic drug‐metabolizing capacity are not routinely available. We evaluated the clinical relevance of pharmacogenomic (PGx) information for key pharmacogenes implicated in medication elimination in older adults presenti …

29.08.2026journal-article

Lung

Optimizing Inhaled Corticosteroid Prescribing in COPD: Evaluating the Impact of Eosinophil Testing on Clinical Outcomes

Jared Hester, David Whipkey, James Ferrell

Abstract Purpose Inhaled corticosteroids (ICS) are recommended for select patients with chronic obstructive pulmonary disease (COPD) based on exacerbation history and blood eosinophil counts. Prior studies suggest that ICS are frequently prescribed outside of guideline-based criteria, and eosinophil testing is inconsistently performed in clinical practice. This study evaluated adherence to Global Initiative for Chronic Obstructive Lung Disease (GOLD) eosinophil criteria for ICS prescribing and associated clinical o …

29.08.2026journal-article

Eskisehir Medical Journal, Eskisehir City Hospital

EFFECTS OF CONSCIOUS CONNECTED BREATHING EXERCISES ON BURNOUT LEVELS, SELF-ESTEEM, AND SELF-COMPASSION AMONG FEMALE HEALTHCARE WORKERS

Gulsum Uysal, Gulhan Yuksel, Merthan Tunay, Azize Yilmaz Gumus

Introduction: Burnout is a public health issue due to its effects on patients and public funds. We aimed to determine the impact of breathing sessions on the levels of burnout, self-esteem, and self-compassion among healthcare workers. Methods: A total of 52 participants were enrolled. The Brief Resilience Scale (BRS), Maslach Burnout Inventory (MBI), Rosenberg Self-Esteem Scale (RSES), and Self-Compassion Scale (SCS) questionnaires were completed prior and after the breathing group sessions. The scores were analyz …

29.08.2026journal-article

Pharmaceuticals

Dopaminergic Radiopharmaceutical Imaging in Parkinsonian Syndromes: From Molecular Targets to Clinical Decision-Making

Wael Jalloul, Cristina Mariana Uritu, Despina Jalloul, Vlad Ghizdovat, Andreia Vranceanu Ciobanu, Bogdan Ionel Tamba, Cipriana Stefanescu, Irena Cristina Grierosu

Parkinsonian syndromes comprise overlapping neurodegenerative and non-degenerative disorders, making aetiological diagnosis difficult, while existing procedural guidance does not fully integrate tracer-specific biology with clinical decision-making, multimodal strategies, and emerging quantitative and pathology-directed biomarkers. This review synthesises evidence on the molecular targets, radiopharmaceutical characteristics, biological interpretation, and clinical applications of dopaminergic single-photon emissio …

29.08.2026journal-article

Denta: Jurnal Kedokteran Gigi

Effect of Low-Level Laser Therapy on The Number of Lymphocytes in Oral Ulcer Healing of Immunosuppressed Rats

Reiska Kumala Bakti, Desiana Radithia, Nurina Febriyanti Ayuningtyas, Fatma Yasmin Mahdani, Ghinaya Shaliha Nursaida Nisa

Background: Glucocorticoid-induced immunosuppression disrupts cellular immune responses, including lymphocyte function, and delays oral traumatic ulcer healing. Low-Level Laser Therapy (LLLT) offers an alternative for healing traumatic oral ulcers in immunosuppressed patients. Objective: To analyze the effect of 650 nm LLLT on the number of lymphocytes in traumatic ulcer tissue of immunosuppressed Wistar rats. Materials and Methods: Experimental laboratory study with a randomized post-test-only control group design …