Therapie & Reha: neue Gesundheitspublikationen – Seite 71

18.08.2026journal-article

International Journal of Ophthalmology

Guidelines for visual cognitive rehabilitation of visual information processing disorders (2025)

Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Eye Diseases, Shanghai 200080, China, Yi Shao, Chun-Nan Zhang, Southeast Vision and Ophthalmology Institute, Fuzhou Southeast Eye Hospital, Fuzhou 350004, Fujian Province, China

Visual information processing (VIP) is essential for perception and cognition. It enables the brain to acquire and integrate visual stimuli into coherent representations. Visual information processing disorder (VIPD) is characterized by impairments in visuospatial ability, visual analysis, and visuomotor integration. These deficits significantly affect daily activities, learning, and occupational performance. The etiology of these disorders is multifaceted, including developmental anomalies, traumatic brain injurie …

18.08.2026journal-article

International Journal of Ophthalmology

Medium-dose intravenous methylprednisolone pulse therapy for thyroid-associated orbitopathy

Bangladesh Eye Hospital, Zigatola Ltd., Dhaka 1209, Bangladesh, Ashfaque Rahman Khan, Riffat Rashid, Department of Oculoplasty, Ispahani Islamia Eye Institute and Hospital, Dhaka 1215, Bangladesh, Farzana Afzal, Syeed Mehbub Ul Kadir, Department of Oculoplasty, National Institute of Ophthalmology & Hospital, Dhaka 1207, Bangladesh

AIM: To evaluate the efficacy and safety of a medium-dose intravenous methylprednisolone (IVMP) pulse regimen for moderate-to-severe active thyroid-associated orbitopathy (TAO), with change in clinical activity score (CAS) as the primary outcome. METHODS: This prospective interventional study was conducted at a tertiary eye care center in Bangladesh between February and November 2022. Patients with active moderate-to-severe TAO (CAS≥3) received IVMP totaling 4.0 g (500 mg daily for 3 consecutive days, followed by 5 …

18.08.2026journal-article

Frontiers in Medicine

Systematic review and meta-analysis of physical rehabilitation on functional recovery in critically ill patients

Gang Wang, Xinghua Li, Linlin Fan, Li Lin, Zhiguo Yu, Qing Fang, Weihua Lu

Purpose Survivors of critical illness frequently experience persistent physical impairment, particularly ICU-acquired weakness (ICU-AW), which contributes to prolonged disability after intensive care. We conducted a systematic review and meta-analysis to evaluate the effects of physical rehabilitation on muscle strength, physical function, health-related quality of life, and clinical outcomes in critically ill adults. Methods Four electronic databases were searched from inception to March 2026. Randomized controlle …

18.08.2026journal-article

Neurology, Neuropsychiatry, Psychosomatics

The effect of cyclobenzaprine therapy on the recovery of daily activities and work capacity in patients with non-specific back and neck pain in real-world clinical practice

D. O. Rozhkov, P. M. Asadullaeva, O. V. Burenkova, Yu. M. Vorontsova, V. V. Galkin, M. N. Dadasheva, I. A. Zhukova, N. G. Zhukova, K. S. Manko, D. V. Milchakov, E. B. Natarova, D. V. Semenchenko, V. Yu. Sokolova, A. P. Solovyov, V. V. Sharykin

Objective: to assess the impact of cyclobenzaprine therapy in real-world clinical practice on the severity of pain, functional capacity and the time taken to return to work in patients with non-specific back and neck pain, as well as to evaluate the drug's safety profile. Material and methods. The multicentre study included 997 patients (full analysis set, FAS) aged 18 years or older, of whom 976 completed the study according to protocol – per-protocol (PP) population. Patients received Reloprim (cyclobenzaprine) a …

18.08.2026journal-article

Advances in Computer and Materials Scienc Research

Research on the Objective and Subjective Evaluation Methods of Speech Quality Driven by Feature Fusion

Pengzhen Yang, Tao Qi, Xin Lv

Aiming at the problem of inaccurate speech quality evaluation caused by the previous subjective evaluation-dominated and insufficient coverage of objective evaluation indicators in military communication equipment speech testing, this paper proposes a subjective and objective comprehensive evaluation method based on feature fusion. It focuses on extracting feature parameters such as range, variance, skewness, and kurtosis to characterize the transmission characteristics of speech signals. Through the automatic extr …

18.08.2026journal-article

British Journal of Occupational Therapy

A scoping review of bereavement interventions: Occupational therapy’s potential role

Bridget Kraus, Juliana Earwood

Background: Bereavement is an inevitable lifespan experience. Bereavement and grief have health and functional impacts, yet occupational therapy practitioners (OTPs) do not currently have an identifiable role in bereavement support. Objectives: To explore current bereavement grief interventions that reasonably fall within the scope of occupational therapy (OT). Methodology: Five databases were searched. Eligibility criteria included peer-reviewed journal quantitative research articles published between 2014 and 202 …

18.08.2026journal-article

WORK: A Journal of Prevention, Assessment & Rehabilitation

Sustainable workforce development: Examining work engagement through the Lens of green human capital and psychological ownership

Rashmi Kumari, Sujata Priyambada Dash, Rajeshwari Chatterjee

Background Organizations increasingly invest in Green Human Capital (GHC) to develop sustainability-oriented capabilities, yet evidence on how it enhances employee Work Engagement (WE) remains limited. Psychological Ownership (PO) rooted in motivation and responsibility research, may explain this relationship, but its mediating role in sustainability contexts remains underexplored. Objective This study examines the direct relationship between GHC and WE and the mediating role of PO, while also analyzing these relat …

18.08.2026journal-article

HAND

Self-Management Exercise Regimen Versus Supervised Hand Therapy in Patients With Dorsal Dislocation or Hyperextension Injury With a Volar Plate Avulsion of the Proximal Interphalangeal Joint: The Randomized Controlled PINOT Study

Dorien A. Salentijn, Priscilla Jawahier, Marit van Barreveld, Tosca Vrolijk-van Hengel, Niels Schep, Marcel G. W. Dijkgraaf, Mark van Heijl, Ruben N. van Veen

Background: Supervised hand therapy (SHT) with early mobilization is recommended for patients with a stable, congruent proximal interphalangeal (PIP) joint after dorsal dislocation or hyperextension injury with a volar plate avulsion. Early mobilization uses a dorsal block splint. A self-management exercise regimen (SMER) may offer a valuable alternative that reduces demand on therapists. We hypothesized that SMER is noninferior to SHT. Methods: Noninferiority was assessed in adult patients in a multicenter, open r …

18.08.2026journal-article

Cancers

Dendritic Cell Dysfunction Underlies Immune Escape After Adoptive Cellular Therapy in Glioblastoma

Dan Jin, Bayli DiVita, Alexandra Reid, Caitland Love, John W. Figg, Connor Francis, Laura Falceto Font, Kaytora Long-James, David Hilferty, Sofia Stansbury, Norman Morikawa, Mathew Sebastian, Steeve Boulant, Duane A. Mitchell, Catherine Flores

Background/Objectives: Glioblastoma (GBM) remains a lethal primary CNS malignancy with limited response to immunotherapy. Adoptive cellular therapy (ACT) improves survival in preclinical models, yet tumors ultimately recur. While T cell exhaustion is a common mechanism of resistance, the contribution of dendritic cell (DC) dysfunction remains unclear. We aimed to define mechanisms of immune escape following ACT, focusing on DC function and the role of hypoxia. Methods: Using a murine glioma model (KR158B-luc), mice …

18.08.2026journal-article

Futures: The Zimbabwe Ezekiel Guti University Journal of Leadership, Governance and Development

The Impact of Occupational Safety and Health on the Performance of Small to Medium Enterprises (Smes) in Zimbabwe

Ileen Savo, Shame Mukoka

The study investigates the impact of health and safety on the performance of small to medium enterprises (SMEs) in Zimbabwe. In Zimbabwe, SMEs significantly contribute to the nation`s economy, helping to eradicate hunger and poverty, generating employment and boosting economic growth, hence the need to promote a healthy and safe environment for them. This study uses quantitative methods to collect and analyse data from 289 respondents, drawn from different respondents employed in SMEs in Zimbabwe. A structured onli …

18.08.2026journal-article

Turkish Journal of Gastroenterology

Lumen-Apposing Metal Stent as a Salvage Therapy for Corrosive-Induced Gastric Outlet Obstruction: A Case Report

Mucahit Ergul, Oguz Ozturk, Mehmet Rasit Ayte, Kadir Can Acun, Emir Tugrul Keskin, Ali Atay, Yavuz Cagir, Ilhami Yuksel

Cite this article as: Ergul M, Ozturk O, Ayte MR, et al. Lumen-apposing metal stent as a salvage therapy for corrosive-induced gastric outlet obstruction: A case report. Turk J Gastroenterol. Published online August 18, 2026. doi: 10.5152/tjg.2026.25719

18.08.2026journal-article

Healthcare

Risk-Adaptive Cardio-Oncology Rehabilitation: A Narrative Review of Exercise Prescription, Multimodal Monitoring, and Implementation Pathways

Min Luo, Xiangeng Hou, Yangguang Yu, Yingying Zheng, Xiang Xie

Background/Objectives: Cardiovascular toxicity and pre-existing cardiovascular disease can affect cancer-treatment tolerance, functional recovery, and survivorship. This narrative review aimed to summarize current evidence and propose an author-derived risk-adaptive clinical framework for adult cardio-oncology rehabilitation (CORE), organized around exercise prescription, multimodal monitoring, and implementation. Methods: PubMed/MEDLINE and the Web of Science Core Collection were searched from database inception t …

18.08.2026journal-article

Occupational Health

Mental Health Counselors’ Adaptive Functioning: Exploring Burnout, Occupational Well-Being, and Psychological Resources

Akorede A. Teriba, Amber M. Peterson, Alison C. Rollag, Ryan E. Flinn, Andrew C. Lenway, Zhihao Tang, Adewale Lukman

Mental health counselors routinely work in emotionally demanding environments that require sustained psychological and occupational functioning. Identifying psychological resources and occupational factors that support adaptive functioning may inform strategies to enhance counselor well-being and reduce burnout. This study examined the relationships among counselors’ clinical service context, emotion regulation, growth mindset, self-compassion, job satisfaction, and burnout. Participants were 152 individuals with g …

18.08.2026journal-article

Japanese Journal of Clinical Oncology

De-escalation of perioperative systemic therapy for early breast cancer

Makiko Ono, Yasuaki Sagara, Toshiyuki Ishiba, Yukinori Ozaki, Takehiko Sakai, Hideo Shigematsu, Akihiko Shimomura, Kazuki Sudo, Kaori Terata, Yoichi Naito, Kazuki Nozawa, Fumikata Hara, Tomomi Fujisawa, Tadahiko Shien

Abstract Breast cancer is the most common malignancy among women worldwide, and the number of survivors continues to increase owing to earlier detection and advances in treatment. As long-term survivorship becomes increasingly important, minimizing treatment-related toxicity without compromising oncologic outcomes has become a major goal in the management of early breast cancer. Treatment de-escalation strategies have therefore attracted considerable attention. In HER2-positive disease, several approaches have been …

18.08.2026journal-article

WORK: A Journal of Prevention, Assessment & Rehabilitation

Managing risk and reward: Exploring immigrant platform workers’ occupational safety and wellbeing through a sociotechnical lens

Atieh Razavi Yekta, Suzanne Huot, Heather O'Brien, Christopher McLeod

Background The rise of digital platforms and algorithmically-managed labour is reshaping traditional understandings of job quality, safety, and wellbeing. Objective This study examines how human and non-human factors shape immigrant workers’ perceptions and experiences of safety and wellbeing in the platform economy of Metro Vancouver, Canada. Methods Guided by a sociotechnical lens, the study employed a focused ethnographic design, drawing on content analysis of twenty-one policy-relevant documents and thirty semi …

18.08.2026journal-article

Cosmetics

Localized Topical Melatonin Therapy Promotes Hair Regrowth in C57BL/6 Mice in Association with Wnt/β-Catenin Pathway Activation

Min-Wei Lee, Sheng-Chien Lin, Wen-Ying Chen, Chun-Jung Chen, Yu-Hsiang Kuan, Ming-Kun Hsieh

Melatonin, a methoxyindole synthesized by the pineal gland, is secreted in response to photoperiodic cues relayed from the retina through an endogenous circadian oscillator within the suprachiasmatic nucleus. Consequently, melatonin secretion regulates the circadian rhythm. Melatonin has been reported to have antioxidant, photoprotective, anti-inflammatory, anticancer, and wound-healing properties. It has also been reported to promote hair growth, although the underlying mechanisms remain unclear. In this study, we …

18.08.2026journal-article

The Journal of ECT

Accidental Sugammadex Administration Before Rocuronium During Electroconvulsive Therapy

Tumay Uludag Yanaral, Ayse Ince, Elif Beyza Kucukcingoz

Electroconvulsive therapy (ECT) performed with rocuronium-sugammadex requires both agents to be prepared before each session, creating a persistent syringe-swap risk that compounds with repetition. A 48-year-old woman scheduled for her sixth ECT session received sugammadex 200 mg instead of rocuronium due to syringe misidentification driven by task automaticity accumulated over 5 uneventful preceding sessions. Because the entire sugammadex dose remained unbound in plasma (a state we term “zero-complexation”), subse …

18.08.2026journal-article

Jurnal Keperawatan Profesional

Implementation of 3% Hypertonic Saline Inhalation Therapy and Chest Physiotherapy for Managing Ineffective Airway Clearance in Pediatric Bronchopneumonia: A Case Study

Rizma Amalia, Ai Mardhiyah, Fanny Adistie

Bronchopneumonia remains a leading cause of morbidity and mortality among children. Airway secretion retention may result in ineffective airway clearance. The combination of 3% NaCl inhalation therapy and chest physiotherapy provides complementary mechanisms to liquefy, mobilize, and facilitate the removal of airway secretions. This study aimed to describe changes in airway clearance following the implementation of combined 3% NaCl inhalation therapy and chest physiotherapy in a child with bronchopneumonia. A singl …

18.08.2026journal-article

Blood Cancer Discovery

Outcomes of CAR T-cell Therapy and Bispecific Antibodies as Single-Modality and Sequential Strategies in Relapsed/Refractory Multiple Myeloma

Maximilian Merz, Tomas Jelinek, Thomas Pabst, Raphael Teipel, Anca-Maria Albici, Bastian von Tresckow, Marcel Teichert, Uta Margareta Demel, Antonia Busse, Marie Christine Wesener, Tobias A.W. Holderried, Friederike Schmitz, Friedrich-Linus Rößiger, Fabian Müller, Michele Hoffmann, Friedrich Stölzel, Natalia Tovar, Ben-Niklas Baermann, Martin Stork, Alexandra Jungova, Jiri Minarik, Jakub Radocha, Ivan Spicka, Ludek Pour, Polona Novak, Klara Slajpah, Karla Rener, Ulrich Keller, Stephan Bohl, David Fandrei, Patrick Born, Vladan Vučinić, Nicolaus Kröger, Irene Strassl, Natalie Schub, Roman Hájek, Matjaž Sever, Carlos Fernández de Larrea, Nico Gagelmann

Abstract We explored single or consecutive chimeric antigen receptor (CAR) T and bispecific antibody (BsAb) treatment modalities as correlates of clinical outcomes, by complementary bias-correction analysis of a retrospective multicenter study of 640 patients with relapsed/refractory multiple myeloma. The sequential use of both modalities seemed to yield the most favorable survival trajectories. Initiating treatment with CAR T [idecabtagene vicleucel (ide-cel), ciltacabtagene autoleucel (cilta-cel), cesnicabtagene …

18.08.2026journal-article

Spanish in Context

Frequency and phonological effects on variable noun-adjective order in a spontaneous-speech corpus of Venezuelan Spanish

Juan Berríos, Matthew Kanwit

Abstract Adjective position in Spanish offers a window into how multiple levels of the grammar interact in shaping variable structures. Using a corpus of spontaneous Venezuelan speech, we extracted all noun-adjective pairings for 10 adjectives that permitted variation between pre- and post-position in prior research, yielding 928 variable tokens. Tokens were coded for differences in the syllable length and lexical frequency of the adjective relative to the noun, in addition to the adjective’s semantic class. Result …

18.08.2026journal-article

Terapevticheskii arkhiv

Efficacy and safety of <i>H. pylori</i> eradication therapy in real-world clinical practice: results of the «PAMIR» observational program

Nikolay Yu. Alexeev, Tatyana O. Astaf’eva, Vanda V. Vishnevskaya, Natalia D. Donchenko, Valeria V. Zhuravleva, Polina A. Kruglova, Anastasia A. Kurbatova, Victoria M. Pakhomova, Liyudmila G. Ugay, Irina A. Filipenkova, Irina R. Shigapova, Tatiana L. Lapina, Vladimir T. Ivashkin

Aim. To evaluate the efficacy, safety and impact on gastrointestinal symptoms of Helicobacter pylori eradication therapy with a ready-to-use set of tablets and capsules [omeprazole 20 mg × 2, clarithromycin 500 mg × 2, amoxicillin 500 mg × 4] (Pylobact® AM) in duodenal ulcer patients within the framework of an observational program. Materials and methods. 912 H. pylori-positive patients were included (404 men and 508 women, average age – 43.8 years (43.82±11.39; 18–64 years). Symptoms were assessed using the Gastro …

18.08.2026journal-article

Russian Annals of Ophthalmology

The effect of angiogenesis inhibitor therapy on the risk of fibrosis formation in neovascular age-related macular degeneration and potential strategies for its prevention

A.Zh. Fursova, M.A. Vasilyeva, A.S. Derbeneva, I.M. Amir, M.S. Tarasov, I.F. Nikulich, Yu.A. Karlash, E.R. Agamian

Numerous randomized clinical trials and real-world clinical practice have demonstrated the effect of angiogenesis inhibitors (anti-VEGF agents) on the activity and growth of neovascular complexes in neovascular age-related macular degeneration (nAMD), with a proven reduction in the risk of macular fibrosis, the incidence of which decreased from 39—100% in the “pre-antiangiogenic era” to 20.4—61.4% after introduction of anti-VEGF therapy. The main factors determining the risk of subretinal fibrosis are disease activ …

18.08.2026journal-article

Journal of Discovery Core

<b>Research on Rehabilitation Training Movement Recognition and Real-time Feedback Model Based on Computer Vision</b>

Mingxiang Yang

Aiming at the key problems such as the separation of action recognition and quality assessment tasks, coarse feedback granularity and high labeling cost in the automatic evaluation of rehabilitation training, this paper proposes PDDS‑Net. The framework takes human skeleton sequence as input and realizes action classification and location-level deviation location synchronously through the collaborative architecture of a global action recognition stream and a local part evaluation stream. In the local flow, the joint …

18.08.2026journal-article

Discover Applied Sciences

Multifunctional chitosan/carbon nanotube nanocomposites for programable drug and gene delivery in cancer therapy, wound healing and antimicrobial applications

Hawzhin Hashemi, Aref Zahiri Ghareh Mosa, Ketevan Tavamaishvili, Fariborz Sharifianjazi, Seyed Morteza Naghib, Fatemeh Sadat Fateminia

Abstract Chitosan/carbon nanotube (CS/CNT) nanocomposites have emerged as next-generation multifunctional drug delivery platforms by bridging the gap between material science and precision medicine. These systems combine the high surface area, tensile strength and photothermal conversion ability of carbon nanotubes with the biocompatibility, mucoadhesion and functional versatility of CS to provide a synergistic solution to long-standing limitations of conventional nanocarriers. Stimulus-responsive drug release, cus …

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Aktuelle Forschung nach Fachgebiet

Guidelines for visual cognitive rehabilitation of visual information processing disorders (2025)

Medium-dose intravenous methylprednisolone pulse therapy for thyroid-associated orbitopathy

Systematic review and meta-analysis of physical rehabilitation on functional recovery in critically ill patients

The effect of cyclobenzaprine therapy on the recovery of daily activities and work capacity in patients with non-specific back and neck pain in real-world clinical practice

Research on the Objective and Subjective Evaluation Methods of Speech Quality Driven by Feature Fusion

A scoping review of bereavement interventions: Occupational therapy’s potential role

Sustainable workforce development: Examining work engagement through the Lens of green human capital and psychological ownership

Self-Management Exercise Regimen Versus Supervised Hand Therapy in Patients With Dorsal Dislocation or Hyperextension Injury With a Volar Plate Avulsion of the Proximal Interphalangeal Joint: The Randomized Controlled PINOT Study

Dendritic Cell Dysfunction Underlies Immune Escape After Adoptive Cellular Therapy in Glioblastoma

The Impact of Occupational Safety and Health on the Performance of Small to Medium Enterprises (Smes) in Zimbabwe

Lumen-Apposing Metal Stent as a Salvage Therapy for Corrosive-Induced Gastric Outlet Obstruction: A Case Report

Risk-Adaptive Cardio-Oncology Rehabilitation: A Narrative Review of Exercise Prescription, Multimodal Monitoring, and Implementation Pathways

Mental Health Counselors’ Adaptive Functioning: Exploring Burnout, Occupational Well-Being, and Psychological Resources

De-escalation of perioperative systemic therapy for early breast cancer

Managing risk and reward: Exploring immigrant platform workers’ occupational safety and wellbeing through a sociotechnical lens

Localized Topical Melatonin Therapy Promotes Hair Regrowth in C57BL/6 Mice in Association with Wnt/β-Catenin Pathway Activation

Accidental Sugammadex Administration Before Rocuronium During Electroconvulsive Therapy

Implementation of 3% Hypertonic Saline Inhalation Therapy and Chest Physiotherapy for Managing Ineffective Airway Clearance in Pediatric Bronchopneumonia: A Case Study

Outcomes of CAR T-cell Therapy and Bispecific Antibodies as Single-Modality and Sequential Strategies in Relapsed/Refractory Multiple Myeloma

Frequency and phonological effects on variable noun-adjective order in a spontaneous-speech corpus of Venezuelan Spanish

Efficacy and safety of <i>H. pylori</i> eradication therapy in real-world clinical practice: results of the «PAMIR» observational program

The effect of angiogenesis inhibitor therapy on the risk of fibrosis formation in neovascular age-related macular degeneration and potential strategies for its prevention

<b>Research on Rehabilitation Training Movement Recognition and Real-time Feedback Model Based on Computer Vision</b>

Multifunctional chitosan/carbon nanotube nanocomposites for programable drug and gene delivery in cancer therapy, wound healing and antimicrobial applications