Frag' FlorenceEvidenz. Klar. Anwendbar.
Uhr 7/8Sources Journal Tree
Easy Demo

Florence Themenbrowser · Alle Themen · Seite 73

Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

Themen erkunden

Aktuelle Forschung nach Fachgebiet

23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
29.08.2026journal-article

West African Journal of Allied Health Sciences

Hepatoprotective Efficacy of Residual Aqueous Fraction of <i>Bombax costatum</i> Pellegr. Et Vuillet (Bombacacae) Stem Bark Against Carbon Tetrachloride<sub> </sub>Induced A<b>cute Liver Toxicity in Mice</b>

Nuhu Mohammed, Umar Abdullahi, Ahmadu Saleh, Umar Bala Ningi, Muhammad Rabiu Hamza

Introduction: Hepatic disease still remains a major public health problem due to vulnerability of the liver to a variety of metabolic, circulatory, neoplastic, xenobiotic and microbial insults. Liver injury is accompanied with derangement of vital body functions, hence the need to search for efficacious hepatoprotective agents with minimal side effect. This study aimed to evaluate the hepatoprotective efficacy of aqueous fraction of B. costatum stem bark (AFB) against carbon tetrachloride (CCl4) induced acute liver …

29.08.2026journal-article

Journal of Emergency Management

Developing and evaluating simulation-based pandemic preparedness training for prehospital emergency healthcare workers

Seval Çalışkan Pala, Selma Metintaş, Engin Özakın, Veli Görkem Pala

Objective: The primary objective of this study was to compare the effectiveness of computer-based simulation (CBS) and mannequin-based simulation (MBS) on post-training performance among prehospital emergency healthcare workers (PEHWs). Secondary objectives included evaluating within-group pre–post changes and assessing perceived training effectiveness. Methods: This quasi-experimental study was conducted in Türkiye between 2020 and 2021. After standardized online theoretical training, participants were allocated t …

29.08.2026journal-article

Experimental Physiology

Cardiometabolic effects of contrast therapy: A systematic review

Veerle de Haan, Guy Plasqui, Hannah Pallubinsky

Abstract The rising prevalence of overweight and obesity, together with associated cardiometabolic disorders, underscores the need for additional strategies alongside established interventions. The growing popularity of contrast therapy – alternating exposure to heat and cold, a practice common in traditional Finnish sauna bathing – has prompted interest in its potential cardiovascular and metabolic health benefits. This systematic review outlines the acute and chronic effects of contrast therapy on cardiometabolic …

29.08.2026journal-article

Translational Medicine

Algebra vitae: a manifesto for the new mathematics of biology

S. V. Kozyrev

This paper formulates the problem of developing a mathematical language intrinsically suited to the historicity and organized complexity of living systems. The challenge lies not in the insufficient expressive power of modern mathematics, but in its underlying ontological assumptions. The mathematical framework developed for describing inert physical systems encounters fundamental limitations when applied to living systems. Models formulated within this framework cannot adequately describe systems whose state space …

29.08.2026journal-article

Nutrients

Phase-Specific Nutritional Therapy in Critical Illness: When Protein May Help and When It May Harm, from Acute Metabolic Adaptation to Post-ICU Recovery

Mircea Stoian, Adina Stoian, Claudia Bănescu, Sergio Rares Bandilă, Alina Danilesco, Hajnal Finta, Leonard Azamfirei

Background: Nutritional support in critically ill patients remains one of the most debated aspects of intensive care medicine. Although international guidelines have long recomm.ended early nutritional support with progressive protein delivery, recent clinical evidence has questioned the benefit of aggressive early calorie and protein provision during the acute phase of critical illness, highlighting the need for phase-adapted nutritional strategies. Methods: This narrative review summarizes current evidence on ind …

29.08.2026journal-article

BMC Medicine

24h movement behaviours in university students compared to working age and older adults: wearable-based evidence and cardiometabolic health implications

Ju Lynn Ong, Shuo Qin, Tara H Martin, Xin Yu Chua, Chun Siong Soon, Gizem Yilmaz, Lieng Hsi Ling, Falk Müller-Riemenschneider, Woon-Puay Koh, Michael WL Chee

Abstract Background Physical inactivity, sedentary behaviour and inadequate sleep are established risk factors for non-communicable diseases. Although older adults are traditionally expected to be less active and more sedentary than young adults, contemporary social, occupational and educational environments may have changed this. Here, we characterised 24-hour movement behaviours (physical activity [PA], sedentary behaviour [SB], and sleep) across adulthood using wearable devices and examined their cardiometabolic …

29.08.2026journal-article

Journal of Pure and Applied Microbiology

Molecular Docking Analysis of Coumarin and Indole Derivatives Targeting the MexB and GyrB in Multidrug-resistant Pseudomonas aeruginosa Clinical Isolates

Hawraa Natiq Kabroot AL-Fatlawy

Multidrug-resistant (MDR) Pseudomonas aeruginosa has emerged as a significant clinical threat due to its high resistance to multiple antibiotic classes and the limited effectiveness of current therapeutic options. This study aimed to evaluate selected coumarin and indole derivatives targeting the MexB and GyrB proteins of MDR P. aeruginosa using an integrated in silico approach, supported by molecular characterization of clinical isolates. A total of 44 clinical P. aeruginosa isolates recovered from sputum, urine, …

29.08.2026journal-article

Indonesian Journal of Electronics, Electromedical Engineering, and Medical Informatics

An Explainable XGBoost Framework for Mortality Prediction in People Living with HIV Receiving Antiretroviral Therapy

Ni Putu Likayuni Viona, Ngakan Nyoman Kutha Krisnawijaya, Desak Nyoman Widyanthini

Mortality remains an important concern among people living with HIV (PLHIV) receiving antiretroviral therapy (ART), particularly when high-risk patients are not identified early. This study presents an explainable mortality prediction approach based on an optimized Extreme Gradient Boosting (XGBoost) classifier. A retrospective dataset containing 393 clinical records was analyzed. Before model training, duplicate entries were removed, missing values were imputed, categorical variables were encoded, and class imbala …

29.08.2026journal-article

Constellations

The Contested Grounds of Democracy's Noninstrumental Value: Deliberative Democracy Versus Public Equality

Vittorio Gerosa

ABSTRACT Disagreement about democracy's noninstrumental value often sees the opposition between two competing approaches. Liberty‐based arguments assign normative priority to a principle of liberty, thereby focusing on democratic self‐government as the core principle through which political authority can be reconciled with individual liberty. Equality‐based arguments fundamentally appeal to equality instead, thus commending democratic procedures for treating citizens as equals in the decision‐making process. This p …

29.08.2026journal-article

International "Journal of Academic Research for Humanities"

Informal Governance, Community Resilience, and the Making of Public Space

Masooma Mohib Shakir, Samia Sarfaraz

Public spaces in informally developed Global South settlements are frequently studied through a lens of deprivation and institutional neglect, yet research on community-managed public space in marginalized settlements remains limited. Actively used public spaces in such settlements offer critical insight into community-led spatial governance under minimal administrative control. This paper examines how community organization, cultural identity, historical attachment, informal governance, and spatial networks sustai …

29.08.2026journal-article

Journal of Immigrant and Minority Health

Are Group Interventions Effective at Improving Health Outcomes in Culturally And Linguistically Diverse (CALD) Populations With Chronic Conditions? An Umbrella Review

Karma Phuentsho, Emma L. Karran, Ruth P. Appiah, Marinelle Fernandez, Kristin Graham, Saravana Kumar, Saurab Sharma, Amanda C de C Williams, Aparnadas Amritha, G. Lorimer Moseley

Abstract Culturally and linguistically diverse (CALD) populations experience disproportionate burdens of chronic disease compared to the general population; previous research demonstrated group-based interventions improve health outcomes across various chronic conditions. This umbrella review aims to summarise the available evidence concerning group-based interventions for CALD populations with chronic conditions. We conducted this umbrella review in accordance with the Cochrane Handbook for Systematic Reviews of I …

29.08.2026journal-article

PKLI Journal of Health Sciences

Three-year Experience of Antimicrobial Stewardship in a Tertiary Care Hospital in Pakistan: Successes and Challenges

Naseem Salahuddin, Quratulain Shaikh, Samreen Sarfaraz, Aneela Hussain, Aamir Sikander Kazi, Muhammad Hamid Hanif, Mujahid Hussain

Background: Antimicrobial resistance (AMR) is on the rise globally. One strategy proposed by WHO to curtail AMR includes establishing antimicrobial stewardship (AS) programs. The objective of this study was to describe the practices of antimicrobial use at the Indus Hospital and Health Network (IHHN) and share their experience of establishing an AS program. Methods: The Infectious Diseases (ID) department at IHHN, Korangi Campus, established an AS program in 2020. In the first phase (2020-2022), pharmacist-led revi …

29.08.2026journal-article

Diagnostics

Clinical Outcomes and Device-Related Complications Following Flow Diverter Stent Treatment of Unruptured Intracranial Aneurysms: A Single-Center Retrospective Study

Necat Islamoglu, Ali Can Yalcin, Ilker Coven

Background/Objectives: Flow diverter stents are widely used for the treatment of complex, unruptured intracranial aneurysms. Nitinol-based devices offer improved flexibility and vessel conformability; however, real-world clinical outcome data remain limited. This study aimed to evaluate the safety and clinical outcomes of nitinol-based flow diverter stents in a single-center cohort. We hypothesized that these devices would demonstrate high technical success rates, low rates of device-related complications, and favo …

29.08.2026journal-article

EPRA International Journal of Multidisciplinary Research (IJMR)

A STUDY ON THE INCIDENCE OF NEEDLE STICK INJURY (NSI), ASSOCIATED DEMOGRAPHIC FACTORS AND INJURY-RELATED CHARACTERISTICS AMONG NURSING STUDENTS OF SELECTED NURSING INSTITUTIONS OF AIZAWL, MIZORAM

Laldingliani Sailo, Malsawmdawngkimi ., R. Lalruatkimi, Lalremmawii Ralte, Mufeez Ur Rahman

Needle Stick Injury (NSI) is a significant occupational hazard for healthcare workers, especially nursing students during clinical training. Inadequate awareness of standard precautions and post-exposure protocols, like Post-Exposure Prophylaxis (PEP), heightens the risk of serious infections such as Hepatitis B, C, and HIV. This study aimed to assess the incidence of NSI among nursing students in Aizawl, Mizoram, and explore its association with academic year. A total of 830 nursing students participated in a quan …

29.08.2026journal-article

BMC Health Services Research

National trends in inpatient rehabilitation utilization among patients with sepsis in Japan: a nationwide cohort study from 2010 to 2020 by the Japan Sepsis Alliance (JaSA) study group

Taro Imaeda, Yusuke Kawamura, Takehiko Oami, Tatsuro Yokoyama, Satoshi Nakagawa, Hiroshi Ogura, Nobuaki Shime, Yutaka Umemura, Asako Matsushima, Kiyohide Fushimi, Taka-aki Nakada

Abstract Background Rehabilitation is increasingly recognized as an essential component of recovery for patients with sepsis. However, the real-world delivery of rehabilitation services for sepsis has not been characterized at a national level. This study aimed to evaluate temporal trends and patterns in the utilization and delivery of inpatient rehabilitation among patients hospitalized with sepsis in Japan. Methods This nationwide retrospective cohort study used the Japanese Diagnosis Procedure Combination databa …

29.08.2026journal-article

Journal of the Pediatric Infectious Diseases Society

Proven Invasive Fungal Infections in Pediatric Hemato-Oncologic Patients: Clinical Characteristics and Epidemiological Challenges

Marcela Lizeth Morales López, Denisse Natalie Vaquera Aparicio, José Iván Castillo Bejarano, Abiel Homero Mascareñas de los Santos, Rogelio de Jesús Treviño Rangel, Paul Santiago Arcos Viscarra, Ana Sofia Guerrero Delgado

Abstract Background Invasive fungal infections (IFIs) represent a major cause of morbidity and mortality in pediatric hemato-oncologic patients, particularly during periods of profound immunosuppression. Although Candida spp. and Aspergillus spp. remain the most frequently identified pathogens, recent reports have shown an expanding spectrum of emerging molds. Despite improvements in diagnostic tools and antifungal therapy, delays in recognition and initiation of treatment continue to contribute to unfavorable clin …

29.08.2026journal-article

Journal of Clinical Monitoring and Computing

Stable tissue oxygen cerebral perfusion pressure (stoCPP): Proof of concept for a novel method for the assessment of optimum cerebral perfusion pressure in severe traumatic brain injury

Toby Jeffcote, Sung Wook Chung, Anis Chaba, Kuan-Ying Lu, Camila R. Battistuzzo, Jasmin Board, Emma-Leah Martin, D. James Cooper, Andrew A. Udy

Abstract To demonstrate a method for the identification of safe cerebral perfusion pressure (CPP) in patients with severe traumatic brain injury using brain tissue oxygen (PbtO₂) readings as a surrogate marker of cerebral blood flow. Retrospective analysis of prospectively collected data from patients with severe TBI (sTBI). A total of 9 patients with sTBI enrolled in the BONANZA-GT trial with continuous monitoring of mean arterial blood pressure (MAP), intracranial pressure (ICP), cerebral perfusion pressure (CPP) …

29.08.2026journal-article

Maltepe Tıp Dergisi

Association Between Blood Type Clinical Course and Sputum Microorganisms in Bronchiectasis

Güzide Tomas, Ayşe Çapar, Aslı Mezide Dulkadiroğlu, Şeyma Başlılar

Amaç: ABO kan gruplarının çeşitli enfeksiyonlara yatkınlık ile ilişkili olduğu gösterilmiştir. Bronşektazi hastaları sık enfeksiyonlar geçirebilmekte ve bu durum kötü klinik seyir ve olumsuz sonuçlara yol açabilmektedir. Bu çalışmada, kistik fibrozis dışı bronşektazisi olan erişkin hastalarda ABO kan grubu ile klinik seyir ve balgam kültüründe üreyen mikroorganizmalar arasındaki ilişkinin değerlendirilmesi amaçlandı. Materiyal ve metod: Ocak 2016 – Ekim 2024 tarihleri arasında izlenen bronşektazi hastalarının balga …

29.08.2026journal-article

International Journal of Research in Medical Sciences

Touchless monitoring in medical-surgical nursing: clinical applications of radar, camera-based and contact-free vital sign technologies: a narrative review

Sonia Das, K. Gomathi Jaganathan, Divya Upreti, Sufiya Salim Inamdar, Poonam Jadhav, Shubhangi Malavade, P. Vanaja, Tamilselvan, Jaivin Jaisingh J., N. Prabha, Nilesh Surendra Londhe, Mohammed Umar

Touchless monitoring technologies have emerged as an innovative approach to continuous physiological surveillance in medical-surgical nursing by enabling the assessment of vital signs without direct physical contact. Conventional contact-based monitoring systems, although reliable, are associated with limitations such as patient discomfort, skin injury, sensor displacement, false alarms and increased risk of infection transmission. Recent advances in radar-based sensing, camera-based monitoring, remote photoplethys …

29.08.2026journal-article

EMBO Molecular Medicine

A cavity-reduced prefusion RSV F bivalent vaccine elicits durable and protective immunity

Lijie Liu, Mengrong Yan, Ruoxu Liang, Qingxin Wu, Changbin Qu, Huiqi Wu, Zhi Liao, Huiyu Chen, Jingjing Zou, Zeyun Sun, Dongyu Niu, Liyuan Wu, Li Zhao, Jialing Dai, Jialun Shen, Long Zhang, Wei Zhang, Wei Peng

Abstract Respiratory syncytial virus (RSV) remains a major cause of severe respiratory disease, and stabilization of the prefusion (preF) conformation of the F glycoprotein is central for vaccine development. Here, we report a structure-guided engineering strategy that enhances preF stability by reducing the hydrophobic cavity within the trimeric F protein. Targeted modifications at metastability-associated sites generated RVF-88, a disulfide-free stabilized preF immunogen that preserves key neutralizing epitopes, …

29.08.2026journal-article

Archives of Current Research International

Herbal Therapy in the Management of Polycystic Ovary Syndrome: A Critical Narrative Review of Mechanistic Claims, Clinical Evidence and Translational Barriers

Ayushi Masih, V. Paul

Polycystic ovary syndrome, still widely described as polycystic ovarian disease in parts of South Asia, is the most common endocrine and metabolic disorder affecting women of reproductive age. Its management remains symptom directed, and dissatisfaction with conventional pharmacotherapy has helped make herbal preparations one of the most frequently self-administered adjuncts in this population. The purpose of this critical narrative review is to evaluate what the accessible literature can and cannot establish about …

29.08.2026journal-article

Review of Primary Care Practice and Education (Kajian Praktik dan Pendidikan Layanan Primer)

Holistic Approach on Early-Onset Type 2 Diabetes Mellitus Patient with Suspected Mental Retardation and Family History of Metabolic Disease: A Case Report

I Gede Aswin Parisya Sasmana, Made Ayu Kurniati Atmaja, Lorena Samanta Adelina, Wayan Citra Wulan Sucipta Putri, Putu Aryani, Ida Ayu Diah Pramita Kurnia Dewanti, Ida Bagus Made Candra

A 46-year-old unmarried male, Mr. IMAP, presented to a primary health center (Puskesmas) in Bangli Regency accompanied by his father due to persistent fatigue and blurred vision for the past month. The patient has a history of mental retardation since childhood, making communication difficult and necessitating constant support from his father. He was diagnosed with early-onset type 2 diabetes mellitus (T2DM) at the age of 15 and has been attending regular follow-ups at the health center. His recent random blood glu …

29.08.2026journal-article

Issues in Law & Medicine

Beyond Genetic Discrimination: Emerging Challenges in the Age of Artificial Intelligence

Li Li Zhenkang

With the deep integration of artificial intelligence and biotechnology, the paradigm of genetic discrimination is undergoing a fundamental transformation. Rather than relying on specific genetic markers, AI systems may infer individuals’ underlying biological risks through proxy data. This emerging form of discrimination, conceptualized in this article as “Algorithmic Proxy Genetic Discrimination” (APGD), is predictive, opaque, and structural. However, China’s existing Personal Information Protection Law and fragme …