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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
17.08.2026journal-article

Revista Ibero-Americana de Humanidades, Ciências e Educação

ADAPTAÇÕES NEUROMECÂNICAS E FISIOLÓGICAS AO EXERCÍCIO RESISTIDO NA REABILITAÇÃO DE LESÕES ARTICULARES: IMPLICAÇÕES PARA A PRESCRIÇÃO CLÍNICA

Raphael Pinto dos Santos, Marckson da Silva Paula, Ronaldo Lins Meira, Alexandra Frederico Corrêa, Laís Barbosa de Castro Delgado, Maryah Christina dos Santos Senna Nilo, Tatiane da Costa Thedim, Carlos Eduardo das Neves, Luciano Lima dos Santos, Jani Cleria Pereira Bezerra

Objetivo: sintetizar e quantificar as adaptações neuromecânicas, morfológicas e funcionais ao exercício resistido na reabilitação de lesões articulares e traduzir os achados para a prescrição clínica Métodos: revisão sistemática conforme PRISMA 2020, com buscas no PubMed/MEDLINE e PEDro até 30 de julho de 2026. Foram elegíveis ensaios controlados com pessoas a partir de 14 anos, lesão articular traumática ou condição pós-operatória e programa resistido progressivo por pelo menos quatro semanas. O risco de viés foi …

17.08.2026journal-article

Sensors

Adaptive Control of Lower-Limb Assistive Exoskeleton for Rehabilitation Using Deep Reinforcement Learning

Ali Foroutannia, Masoud Mohammadian, Kumudu Munasinghe

Lower-limb rehabilitation exoskeletons have the potential to improve gait recovery after stroke by providing intensive and repetitive training. However, conventional control strategies often rely on fixed control parameters and exhibit limited adaptability to patient-specific characteristics, sensor noise, and dynamic uncertainties. This paper proposes an adaptive control framework that combines deep reinforcement learning (RL) with model-based impedance control for personalised lower-limb exoskeleton assistance. P …

17.08.2026journal-article

International Journal of Molecular Sciences

Placental Growth Factor in Diabetic Retinopathy: Disease-Selective Signaling and Mechanistic Rationale for Targeted Therapy

Jongmin Kim, Won-Kyu Ju, Jae Yon Won

Chronic hyperglycemia disrupts the retinal neurovascular unit, making diabetic retinopathy (DR) the leading cause of adult vision loss. The hallmarks of DR include pathological angiogenesis, vascular leakage, and neurodegeneration. Although vascular endothelial growth factor A (VEGF-A) is a key mediator of these abnormalities and anti-VEGF therapies remain the standard treatment, many patients exhibit incomplete responses, and these therapies do not adequately address inflammation or fibrosis. Placental growth fact …

17.08.2026journal-article

Frontiers in Oncology

Effects of an intensive pulmonary rehabilitation program on postoperative pulmonary complications in frail elderly patients undergoing hepatobiliary and pancreatic surgery: a randomized controlled trial

Jinhua Feng, Fuyu Li, Huan Feng, Hui Ye, Min Gao, Yuanchun Ling, Haijie Hu, Qiang Han, Bairong Shen, Ka Li

Background Frail elderly patients undergoing hepatobiliary-pancreatic (HBP) surgery face a substantially elevated risk of postoperative pulmonary complications (PPCs), which are associated with increased mortality, extended morbidity, and greater healthcare costs. Although the “I Cough” pulmonary rehabilitation program is a well-established preventive strategy for PPCs, its clinical effectiveness is often limited by suboptimal patient adherence. This randomized controlled trial was therefore conducted to determine …

17.08.2026journal-article

Frontiers in Immunology

Chimeric antigen receptor T-cell therapy for rheumatic diseases: from B-cell depletion to immune reset and beyond

Yiqing Zhan, Chao Hu, Keyao Xiao

Rheumatic and autoimmune diseases have long relied on glucocorticoids and immunosuppressants for disease control, yet a true cure remains elusive; patients oscillate between remission and relapse and progressively accumulate irreversible organ damage. Chimeric antigen receptor (CAR) T cells targeting CD19 or B-cell maturation antigen (BCMA) achieve deep depletion of pathogenic B-lineage cells, enabling a subset of patients with systemic lupus erythematosus, idiopathic inflammatory myopathy, and systemic sclerosis t …

17.08.2026journal-article

Advanced Materials

A Wearable Electrochemical Patch for Sustained Local Oxygen Therapy of Chronic Wounds

Jichen Zhao, Xuewei Kan, Xin Tang, Xin Huang, Shuo Li, Shiyu Ji, Yimin Li, Xuyan Zhao, Yi Tan, Ting Si, Guiqiang Li, Chunyu Zhao, Jun Tang, Yu Zhang, Yuen Wu

ABSTRACT Wearable bioelectronics are dominated by low‐power sensing, whereas effective therapy requires sustained molecular fluxes that conventional soft devices rarely support. A central challenge is simultaneously maintaining solid–solid charge transport, hydration‐dependent ionic conduction, and biofluid resistance within a lightweight, fixture‐free architecture. Here, we report a vapor‐fed electrochemical materials architecture for skin‐conformal oxygen delivery. The system integrates a mechanically interlockin …

17.08.2026journal-article

Communications of International Proceedings

Contemporary Determinants of Occupational Burnout Among Accountants: A Narrative Literature Review

Joanna SZWAJCAR

Contemporary organizational environments have led to a systematic increase in the demands placed on accounting professionals, driven by the ongoing digital transformation of accounting processes, the growing complexity of legal regulations, and increasing stakeholder expectations regarding the quality and reliability of financial information. These developments intensify occupational demands and may contribute to the emergence of job burnout. Despite growing scholarly interest in this issue, burnout among accountin …

17.08.2026journal-article

The Journal of ECT

Living With Electroconvulsive Therapy—A Qualitative Study of the Subjective Experiences of Patients Having Continuation or Maintenance Electroconvulsive Therapy

Prashanth Mayur, Nyan Du, Anthony Harris, Venkat Ramakrishnan, Jagadeesh Andepalli, Beatriz López-Portillo

Objective: To explore the subjective experience of patients receiving continuation/maintenance electroconvulsive therapy (C/M-ECT) for severe, recurrent mental illnesses, addressing a literature gap in this unique cohort whose perspective remains unexplored. Methods: An exploratory qualitative study was conducted on 10 voluntary adult patients (aged 32 to 66 y) from outpatient C/M-ECT services in Western Sydney Local Health District and St John of God Richmond Hospital, Sydney, Australia. Participants, primarily wi …

17.08.2026journal-article

Adolescência e Saúde

Effect Of Intranasal Therapy On Serum Periostin Levels In Allergic Rhinitis: A Comparative Study

Dr. Dhanya Boopathe, Dr Jitesh Kumar Baskaran

Background: Allergic rhinitis (AR) is a chronic inflammatory disease driven by Type 2 immune responses. Periostin, an IL-4/IL-13–induced matricellular protein, has emerged as a biomarker of allergic inflammation. This study evaluated the effect of intranasal therapy on serum periostin levels and correlated these changes with clinical outcomes, comparing TriVital Mix with standard therapy. Methods: Thirty patients with AR were randomized into two groups: standard therapy and TriVital Mix. Clinical scores (SNOT-22, N …

17.08.2026journal-article

Europace

Management of Recurrent Atrial Fibrillation After Catheter Ablation: Five-Year Outcomes of Repeat Catheter Ablation Versus Antiarrhythmic Therapy

Yong Hao Yeo, Hermon Kha Kin Wong, Aravinthan Vignarajah, Min Choon Tan, Nishanthi Vigneswaramoorthy, Justin Lee, Luis Scott, Kamala P Tamirisa, Dan Sorajja, Christopher DeSimone

Abstract Background Recurrence of symptomatic atrial fibrillation (AF) after catheter ablation (CA) is not uncommon. However, real-world long-term data on clinical outcomes of rhythm control strategies in patients with recurrent AF after CA remain limited. Methods Using the TriNetX database, we identified adult patients (≥18 years) with recurrent AF after index CA. A 3-month blanking period was applied, during which no rhythm-control therapy was received. Patients were classified into two groups: repeat CA or initi …

17.08.2026journal-article

Modern Rheumatology Journal

Resolution of the Expert Council “Reproductive health of patients with rheumatic diseases during targeted therapy: from preconception preparation to postpartum follow-up”

E. L. Nasonov, A. M. Lila, T. V. Dubinina, P. A. Shesternya, E. A. Trofimov, G. V. Lukina, A. I. Zagrebneva, N. M. Kosheleva, N. I. Klimenchenko, Yu. A. Koloda, I. P. Nikishina, P. I. Novikov, S. P. Yakupova, L. P. Evstigneeva, I. M. Patrikeeva, L. V. Ivanova, O. N. Anoshenkova, I. A. Cherentsova, A. Yu. Skripkin

On June 19, 2026, a meeting of the Expert Council was held to discuss reproductive health issues in patients with immune-mediated inflammatory rheumatic diseases and the safety of antirheumatic therapy. Rheumatologists, obstetrician-gynecologists, reproductive medicine specialists, and other experts participated in the discussion.

17.08.2026journal-article

Research Connections

Radiologically Suspected Locally Recurrent Rectal Cancer Presenting with Rectal Perforation and Rectocutaneous Fistula Years After Multimodal Therapy: A Case Report

Donia Zarzour, Philippe Attieh, Antonio Al Hazzouri, Tya Youssef, Rim Moubayed, Lamia Azizi, Karam Karam

Abstract Background Local recurrence of rectal cancer after multimodal therapy may be difficult to distinguish from post-radiation changes and can lead to severe complications if diagnosis is delayed. Case Presentation We report the case of a 62-year-old woman with previously treated rectal adenocarcinoma who developed PET/CT findings suspicious for local recurrence despite benign colonoscopic biopsy showing post-radiation changes. Subsequent imaging demonstrated disease progression, and the patient presented with …

17.08.2026journal-article

Revista Ibero-Americana de Humanidades, Ciências e Educação

POLÍTICAS PÚBLICAS PARA ENFRENTAMENTO AO DISCURSO DE ÓDIO E PREVENÇÃO DE LITÍGIOS

Camilo Onoda Luiz Caldas

No presente artigo desenvolvemos uma análise do discurso de ódio como fenômeno jurídico e social, examinando os fundamentos normativos — nacionais e internacionais — que o repudiam, bem como as políticas públicas disponíveis para seu enfrentamento e para a consequente prevenção de litígios. A pesquisa parte da premissa de que a resposta estatal ao discurso de ódio não pode ser reduzida à via punitiva, demandando uma arquitetura intersetorial de políticas preventivas, educativas e reparatórias. Do ponto de vista met …

17.08.2026journal-article

Journal of Medicine and Health Research

Artificial Intelligence in the Optimisation of Glucagon-Like Peptide-1 Receptor agonist Therapy for Obesity and Type 2 Diabetes: A Critical Narrative Review of Treatment Monitoring and Clinical Decision Support

Mirembe Katabaazi Lillian, Anyebe Daniel Ameh, Jacob Miracle Godswill, Nana Ama Aduma Amankwah

Glucagon-like peptide-1 receptor agonists have changed what can be achieved pharmacologically in obesity and type 2 diabetes, yet the average effects reported in registration trials conceal wide interindividual variation in weight and glycaemic response, high rates of early discontinuation, incomplete dose escalation in routine care, and pronounced inequity in who receives treatment. These features have prompted the claim that artificial intelligence, and machine learning in particular, can improve candidate select …

17.08.2026journal-article

Clinical and Experimental Dermatology

Localized bullous pemphigoid arising within sites of radiation in the context of immune checkpoint inhibitor therapy

W Austin Wyant, Lara Drake, Antonio Ji-Xu, Dhruv Singhal, Anupam M Desai, Christopher Iriarte

There is minimal literature on the development of localized bullous pemphigoid exclusively in previously irradiated skin. We report two patients with bullous pemphigoid strikingly localized to areas of previous radiation therapy that occurred in the setting of concomitant immune checkpoint inhibitor therapy.

1 Zitationen
17.08.2026journal-article

WORK: A Journal of Prevention, Assessment & Rehabilitation

Driven or drained? How addiction to work shapes the effects of need satisfaction on well-being at community-based work

Marta P Alves, Vítor Costa, Ana I Cunha, Ludovina Ramos

Background The theoretical framework of the study draws on Self-Determination Theory (SDT), Job Demands–Resources (JD-R) theory, and Conservation of Resources (COR) theory. Objective The study explores the association between the satisfaction of basic psychological needs at work and psychological well-being, and the role of work addiction as a moderator of that relationship, distinguishing between the effects of excessive and compulsive work. Methods Participants were 204 employees involved in community-based work …

17.08.2026journal-article

Child Language Teaching and Therapy

What is a good outcome in speech and language therapy and how can this be achieved? Exploring the views of school-aged children and parents

Caroline Tiong, Jane McCormack, Anna Cronin

Speech and language therapists are guided by standards and frameworks that emphasise client contributions to decision-making and holistic outcomes. Currently, there is little known about the preferences of school-aged children with speech, language and communication needs (SLCN) for speech and language therapy services. This study explored the perspectives of five primary school-aged children with SLCN and their parents about their preferred experiences of speech and language therapy and what they identified as suc …

17.08.2026journal-article

Frontiers in Oncology

Associations between pretreatment composite inflammatory indices and pathological response to neoadjuvant therapy in breast cancer: a retrospective cohort study

Yuhong Zhang, Cailing Tong

Background Pretreatment inflammatory indices may reflect the host immune-inflammatory status in breast cancer. Evidence comparing multiple composite indices across pathological response endpoints after neoadjuvant therapy remains limited. This study evaluated the associations between pretreatment composite inflammatory indices and pathological response in breast cancer. Methods This retrospective study included 280 patients with breast cancer who underwent neoadjuvant therapy followed by surgery. Baseline neutrophi …

17.08.2026journal-article

Journal of Clinical Medicine

Biologic Therapy Is Associated with Reduced Pleural-Line Thickness in Severe Asthma: A Prospective Transthoracic Ultrasound Study

Müge Erbay, Selçuk Akkaya, Funda Öztuna, Hatice Tayar

Background/Objectives: Tissue-level markers of treatment response are lacking in severe asthma. Transthoracic ultrasound (TUS) non-invasively detects pleural-line and subpleural abnormalities that have been linked to small-airway disease, but it has not been evaluated as a marker of response to biologic therapy. The primary objective was to determine whether mean pleural-line thickness in the right and left hemithoraces changed between baseline and week 16 of biologic therapy. The secondary objectives were to descr …

17.08.2026journal-article

Wiener Medizinische Wochenschrift

Extracorporeal shockwave therapy as a key component of interdisciplinary wound management in diabetic foot syndrome

Richard Crevenna, Zoltan Vass, Michael Mickel, Michael Leutner, Shuren Li, Mohammad Keilani

Summary Background A 57-year-old male patient presented with the first manifestation of severe type 2 diabetes mellitus in the setting of diabetic foot syndrome complicated by osteomyelitis. Methods The patient was treated conservatively within a multimodal interdisciplinary approach. In addition, focused extracorporeal shockwave therapy (fESWT) was performed according to International Society for Medical Shockwave Treatment (ISMST)-oriented principles. Results After five sessions of fESWT, local wound management r …

17.08.2026journal-article

Archivos en Medicina Familiar

Calidad de vida en pacientes con nefropatía diabética y terapia sustitutiva renal

Yanet Flores Morales, Itzia I. Corona Candelas, Citlalli Orizaga de la Cruz, Anel Gómez García, María P. Rodríguez Correa

Objetivo: Comparar la calidad de vida en pacientes con nefropatía diabética sometidos a diálisis continúa ambulatoria y hemodiálisis. Métodos: Estudio observacional, transversal y prospectivo realizado en la Unidad Médica de Atención Ambulatoria 254 de Morelia Michoacán, México del Instituto Mexicano del Seguro Social. Se efectuó de diciembre 2023 a abril 2024, fueron incluidos 136 pacientes con nefropatía diabética en diálisis peritoneal continua ambulatoria y hemodiálisis. Para evaluar la calidad de vida se aplic …

17.08.2026journal-article

Biomolecules

Two Faces of the Right Ventricle in Fabry Cardiomyopathy: Septal-Coupled and Atrial-Coupled Strain Patterns and Their Differential Associations with Enzyme Replacement Therapy

Kuo-Tzu Sung, Dau-Ming Niu, Shu-Fen Hsu, Ming-En Liu, Po-Lin Lin, Yau-Huei Lai, Hsiang-Wei Yang, Yung-Hsiu Lu, Cheng-Ting Tsai, Ta-Chuan Hung, Po-Sheng Chen, Chung-Lieh Hung

Right ventricular global longitudinal strain (RVGLS) and right ventricular free-wall longitudinal strain (RVFWLS) are both used to assess right ventricular involvement, but they include different myocardial components. We examined their cross-sectional correlates and longitudinal changes associated with enzyme replacement therapy (ERT) in 100 patients with genetically confirmed Fabry disease, including 69 with serial echocardiography. RVGLS was independently associated with left ventricular global longitudinal stra …

17.08.2026journal-article

International Journal of Molecular Sciences

Recent Advances in Therapy for the Neurodegenerative Disorder Ataxia-Telangiectasia

Sam Nayler, Simon Foster, Martin Lavin, David Coman

At present, there is no cure for the human genetic disorder ataxia-telangiectasia (A-T), which is managed by supportive care. This disorder arises due to mutations in the ATM (ataxia-telangiectasia mutated) gene and is characterised by a defect in the response to DNA damage, oxidative stress, mitochondrial dysfunction and immune deficiency. The ATM protein is activated by DNA damage, reactive oxygen species (ROS), and a variety of other stimuli, which leads to the phosphorylation or altered cellular localisation of …

17.08.2026journal-article

Journal of Clinical Medicine

Occupational Contact Dermatitis in the Post-COVID Era: From Barrier Dysfunction and Microbiome Dysbiosis to Prevention and Precision Management

Laura Maghiar, Andrada Iftode, Teodor-Andrei Maghiar, Raul Chioibas, Titus Grecu, Carmen Neamțu, Sandor Mircea Ioan, Cristina-Adriana Dehelean, Cristina Dumitrescu, Andreea-Adriana Neamțu

Background/Objectives: Occupational contact dermatitis (OCD) is the most common work-related skin disease, accounting for roughly 90–95% of occupational dermatoses and falling predominantly on the hands. It is rarely dangerous yet imposes a substantial burden through impaired quality of life, lost productivity, and premature exit from affected trades. The COVID-19 pandemic intensified this burden among healthcare workers, in whom the pooled one-year prevalence of self-reported hand eczema reaches around 27%; meta-a …