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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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22 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
27.08.2026journal-article

Journal of Public Health in Africa

Signal integration challenges in African epidemic intelligence: Lessons from the 2026 Bundibugyo virus disease outbreak and application of the PREIS framework

Hyacinthe R. Zabre

On 17 May 2026, the Director-General of the World Health Organization determined that Ebola disease caused by Bundibugyo virus in the Democratic Republic of the Congo (DRC) and Uganda constituted a Public Health Emergency of International Concern. Ten days separated the initial alert (05 May) from laboratory confirmation (15 May) although multiple non-laboratory signals were already active. Using this outbreak, we argue that Africa’s principal detection challenge is often not signal availability but the timely inte …

27.08.2026journal-article

Clinical Science

Combined 31P and 1H MRS show that impaired muscle O2 supply limits ATP synthesis during exercise in systemic sclerosis

Graham J. Kemp

Abstract Muscle weakness and fatigue feature in many diseases, but the underlying pathophysiology can be difficult to study in vivo. In patients with the chronic autoimmune disease systemic sclerosis (SSc), considerable disability results from small-vessel vasculopathy and progressive fibrosis. Alongside cardiopulmonary limitations on exercise capacity, there is increasing evidence of peripheral dysfunction. In a study reported in this issue, Layec and colleagues investigate this in exercising skeletal muscle in vi …

27.08.2026journal-article

Karya Journal of Health Science

ACUTE EFFECTS OF FOAM ROLLING AND PNF STRETCHING AS WARM-UP STRATEGIES ON MUSCLE FLEXIBILITY, STRENGTH, AND PRESSURE PAIN THRESHOLD IN AMATEUR ATHLETES

Elif Esma Bayraktar, Hayri Eren Yılmaz, Birce Beril Çelik, Mahmut Efe Bükülmez, Eren Çekiç

Objective: This study aimed to compare the acute effects of foam rolling (FR) and proprioceptive neuromuscular facilitation (PNF) stretching on hamstring flexibility, isometric knee flexion strength, vertical jump performance, and pressure pain threshold (PPT) in amateur athletes.Method: Seventy-six amateur athletes were randomly allocated to either the FR group (n=36) or the PNF stretching group (n=40). Following a standardized 5-minute aerobic cycling warm-up, participants received either 3×30 seconds of unilater …

27.08.2026journal-article

International Journal of Health and Pharmaceutical (IJHP)

Hypoglycemia Incidence Among Patients With Type 2 Diabetes Mellitus Receiving Antidiabetic Therapy: A Retrospective Hospital-Based Study in South Kalimantan, Indonesia

Nadiyah Wafa, Tyas Setia Nugraha, Herda Ariyani

Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disease with an increasing prevalence. Antidiabetic drugs (OAD) are necessary for glycemic control, but they carry the risk of causing hypoglycemia. Objective: This study aimed to assess patient characteristics, OAD usage patterns including drug type, dosage, and regimen, hypoglycemic complaints, and side effect categories using the Naranjo Algorithm. Method: A descriptive, observational quantitative study with a retrospective, non-experimental design was condu …

27.08.2026journal-article

Alzheimer's Research & Therapy

Association of self-reported hearing loss and tinnitus with brain structure and cognitive function: a population-based cross-sectional analysis from the Study of Health in Pomerania (SHIP)

Claudia Schwarz, Stefan Frenzel, Till Ittermann, Ulrike Grittner, Silke M Wortha, Tina Brzoska, Hans J Grabe, Agnes Flöel, Friedrich Ihler

Abstract Background Hearing loss has been reported as a major, potentially modifiable risk factor for dementia and often co-occurs with tinnitus. Both conditions are prevalent and have been linked to brain health and cognitive decline. However, evidence from studies containing the whole age span of adults remains limited. Therefore, this study investigated associations of hearing loss and tinnitus with brain structure and cognitive performance in a large population-based cohort from northeastern Germany. Methods Da …

27.08.2026journal-article

Sexual Health

Antimicrobial prescribing quality for sexually transmitted infections: a scoping review

Harlan Smith, Josephine Wen, Zohal Rashidzada, Jenna Maleki, Xin Fang, Karin Thursky, Rodney James, Courtney Ierano

Sexually transmitted infections (STIs) place a substantial burden on outpatient health care and are a key focus for antimicrobial stewardship due to rising antimicrobial resistance. Suboptimal treatment can result in ongoing transmission, reinfection and complications, such as pelvic inflammatory disease. Evaluating prescribing quality is essential to improve patient care and support stewardship efforts. This review synthesises evidence on antimicrobial prescribing quality for STIs and identifies gaps to inform tar …

27.08.2026journal-article

BMC Public Health

Neonatal admissions in a conflict-affected setting: an eight-year multi-center retrospective cohort study from Taiz, Yemen (2018–2025)

Galal Faisal Albani, Khalil A. Saleh, Mokhtar Abdu Almoliky, Naif Taleb Ali, Mujeeb A. Sultan, Eman Shaker Mohammed, Doaa Sadeq Abdullah, Marwa Sadeq, Seham Gameel Mohammed, Angham Mohammed, Abrar Razzaz Mohammed

Abstract Background Neonatal mortality in conflict-affected regions is a critical and under-documented public health issue. This study aimed to characterize admission patterns, diagnoses, and outcomes of neonates in Taiz, Yemen, over an eight-year period. Methods We conducted a multi-center retrospective cohort study. All neonates ( N = 1,936) admitted to five major hospitals in Taiz governorate between January 1, 2018, and December 31, 2025, were included. Data were extracted from hospital registries. Primary outc …

27.08.2026journal-article

Psychiatric Quarterly

Longitudinal association between concurrent changes in social support and mental health symptoms among low-income U.S. veterans: a 2-year follow-up study

Jack Tsai, Bijeta Pradhan, Md Faruk Hossain, Vahed Maroufy

Abstract Social support is known to be able to buffer against psychological stressors, but further study is needed on how different types of social support and mental health change together over time, especially in special populations like U.S. veterans. Social support can also be divided into four types: Emotional Support/Informational Support, Positive Social Interaction, Tangible Support, and Affectionate Support. Using a longitudinal, nationally representative sample of 735 low-income U.S. veterans over 2 years …

27.08.2026journal-article

Journal of Clinical and Translational Research

Can hydrogen-rich water increase nitrite and nitric oxide in patients with central obesity?

Ram B. Singh, Monika Jankajova, Divyank Sharma, Sarthak Sharma, Mohammad Arif Niaz, Oleg Medvedev, Peter Stefanic, Alexander Tarnava, Duried Alwazeer, Emel Uçarer, Najah Hadi, Jagdish Prasad Sharma

Background: Inflammation and oxidative stress play important roles in the pathophysiology of cardiovascular diseases. Hydrogen therapy, due to its antioxidant activity, has become a supplementary treatment. Objective: This study aims to investigate whether hydrogen-rich water (HRW) affects nitrite levels, a precursor of nitric oxide. Methods: Of 71 patients who volunteered, only 60 were selected due to the presence of metabolic syndrome and were randomly divided into either an intervention (HRW; n = 30) or placebo …

27.08.2026journal-article

Arthritis & Rheumatology

Plasma proteome reflects tissue damage and clinical manifestations in patients with inflammatory myopathies

Yue‐Bei Luo, Josefin Kenrick, Angeles S Galindo‐Feria, Antonella Notarnicola, Ana Daniela Ulloa Navas, Irene Peralta‐Garcia, Orane Demuynck, Andrea Kemp, Valérie Leclair, Karin Lodin, Eveline Van Gompel, Lara Dani, Fabricio Espinosa‐Ortega, Maryam Dastmalchi, Leonid Padyukov, Charlotta Preger, María Bueno Álvez, Mathias Uhlén, Peter Nilsson, Fredrik Edfors, Lina‐Marcela Diaz‐Gallo, Elisa Pin, Ingrid E Lundberg, Begum Horuluoglu

Objective Tissue‐specific biomarkers that are reliable and associated with clinical manifestations of idiopathic inflammatory myopathy (IIM) are lacking. The blood circulation in individuals serves as a central conduit, allowing communication between tissues and facilitating clearance and recycling of tissue‐derived proteins. Thus, we applied a dual antibody‐based proximity extension assay to profile >1000 proteins in subtypes of patients with IIM. Methods Plasma samples from 201 patients diagnosed with IIM at Karo …

27.08.2026journal-article

One Health Advances

Comparative genomics of the streptococcal mobilome reveals class-specific integration, mobility and antimicrobial resistance cargo

Kaiwei Nie, Xingyang Dai, Jiaqi Zhao, Mengjie Qi, Cai Yin, Xiaoming Wang, Liping Wang, Jinhu Huang

Abstract Mobile genetic elements (MGEs) drive genome plasticity, horizontal gene transfer, and antimicrobial resistance (AMR) dissemination in Streptococcus , yet genus-wide comparisons across major MGE classes remain limited. Here, we analyzed 1961 complete chromosomes from 60 Streptococcus species together with 225 plasmids, and compared integrative and conjugative elements (ICEs), integrative and mobilizable elements (IMEs), prophages, and plasmids with respect to host distribution, boundary-supported integratio …

27.08.2026journal-article

Bioinformatics

Finetuning Foundation Models for Temporal Clinical Transcriptomics Data

Sachin Mathur, Alexander Kagan, Peyman Passban, Hamid Mattoo, Euxhen Hasanaj, Ziv Bar-Joseph

Abstract Background Timeseries clinical transcriptomic datasets offer the opportunity to gain insights into the dynamics of disease mechanisms/treatment responses. However, their utility in uncovering temporal patterns is often limited by high noise levels and small sample sizes. Leveraging foundational gene embeddings and incorporating interaction information can help address these challenges, improve gene network analysis, and enable the detection of subtle changes that drive disease progression or drug response. …

27.08.2026journal-article

Life

Recent Advances in Biomarkers of Systemic Sclerosis-Associated Interstitial Lung Disease: Clinical Relevance and Therapeutic Perspectives

Rasha-Ioana Rămoiu-Shehada, Anca Emanuela Mușetescu, Lucian-Mihai Florescu, Alesandra Florescu, Paulina-Lucia Ciurea

Systemic sclerosis-associated interstitial lung disease (SSc-ILD) is the leading cause of mortality in patients with systemic sclerosis and a major clinical challenge due to its heterogeneous presentation and variable disease course. Reliable biomarkers may improve disease assessment, risk stratification, and therapeutic decision-making. This narrative review summarizes current evidence on established and emerging serum and molecular biomarkers in SSc-ILD and their potential clinical applications. Recent advances h …

27.08.2026journal-article

Diversity

Early Biodiversity Responses to Underwater Marble Sculptures Deployed as Artificial Reefs: First Scientific Assessment of a Conservation Initiative in the Northern Tyrrhenian Sea

Guia Consales, Francesca Capanni, Lorenzo Minoia, Enrica Franchi, Piergiorgio Stipa, Bianca Bencini, Massimiliano Maschio, Giovanni Contardi, Letizia Marsili

Marine coastal ecosystems are increasingly affected by habitat degradation and loss of structural complexity, with negative consequences for biodiversity, particularly in the Mediterranean Sea. In the Talamone coastal area (Northern Tyrrhenian Sea), additional local pressures include episodes of illegal bottom trawling; however, anti-trawling mitigation actions in the area have been implemented through the deployment of concrete blocks along the coast, whereas underwater artistic installations were conceived primar …

27.08.2026journal-article

Inquiry@Queen's Undergraduate Research Conference Proceedings

Integrating Anti-Racism in Health Education

Bisola Olaseni

Systemic racism embedded within health education contributes to persistent health inequities, yet anti-racism training remains inconsistently integrated into undergraduate health sciences curricula in North American contexts. In response to identified gaps, Queen’s University developed GLPH 281: Racism and Health in Canada, a semester-long, credit-bearing course co-designed by faculty, students, and teaching assistants and embedded within the Bachelor of Health Sciences program. This study documents the implementat …

27.08.2026journal-article

Clinical and Translational Science

Hematological Malignancy Trials in Chinese Mainland, 2013–2022: A Landscape Analysis with Exploratory Macro‐Level Temporal Correlations

Jianwei Qi, Jiajia Gao, Zhenxiao Huang, Bingxuan Li, Yi Yue, Lijun Liu, Meimei Xu, Liang Huang, Shuo Chen, Qing Ji, Zhen Song, Qiujin Shen, Shihui Ma, Shuhua Yi, Xiaochen Wang, Tao Cheng, Lihong Shi, Lei Zhang

ABSTRACT Given the increasing disease burden of hematological malignancies in Chinese Mainland, a systematic analysis of clinical trials is essential to advancing translational medicine, as these trials serve as the critical nexus between laboratory discoveries and clinical applications. This study integrated registration data from the Center for Drug Evaluation, Chinese Clinical Trial Registry, and ClinicalTrials.gov for trials recorded between 2013 and 2022. Using joinpoint regression and descriptive temporal‐cor …

27.08.2026journal-article

Contemporary School Psychology

Universal Mental Health Screening in California School Settings: Current Practices, Barriers, and Opportunities

Stephanie A. Moore, Samira Soleimanpour, Sara Geierstanger, Jessica Yu, Eric M. Davidson, Kali Patterson

Abstract When implemented as part of a multi-tiered system of support, universal mental health screening (UMHS) can facilitate early identification and data-based decision-making in support of students’ social, emotional, behavioral, and mental health needs. Despite increasing interest in school-based UMHS, its widespread uptake has historically been stagnant. Recent national estimates indicate that rates of UMHS implementation are increasing; however, the information available about current practices, as well as t …

27.08.2026journal-article

Blood Pressure Monitoring

Effects of home-based isometric handgrip or aerobic training on blood pressure variability and vascular health in older adults with elevated blood pressure and hypertension: secondary results from The HoldAge Trial

Diogo Pinto, Nuno Dias Rato, Catarina Garcia, Manuel Teixeira, Maria J. Marques, Teresa Amaral, Leonor Amaral, Ricardo Abreu, Cristiana Carneiro, Ana P. Oliveira, Daniela Figueiredo, Jorge Polónia, José Mesquita-Bastos, João L. Viana, Linda S. Pescatello, Fernando Ribeiro, Alberto J. Alves

Background Hypertension is a multifactorial condition that is likely to affect older adults. We evaluated the effects of home-based isometric handgrip training (IHT) or aerobic exercise training (AET) on vascular health of older adults with elevated blood pressure (BP) and hypertension. Methods The HoldAge trial (NCT04275032) was a two-center prospective randomized controlled trial. Eighty-four participants (46 women, 71.1 ± 3.6 years, BP: 137.1 ± 13.8/80.8 ± 8.3 mmHg) were randomized into IHT, AET, or usual medica …

27.08.2026journal-article

Systems Engineering

What Is the Return on Investment of Digital Engineering for Complex Systems Development Schedules? Findings From a Mixed‐Methods Case Study on the Post‐Production Design Change Processes of Navy Assets

Jannatul Shefa, Taylan G. Topcu

ABSTRACT Complex engineered systems routinely face schedule and cost overruns, along with poor post‐deployment performance. Both INCOSE and the U.S. Department of Defense (DoD) have championed Digital Engineering (DE) as a potential remedy, yet most of DE's purported benefits remain anecdotal, and its return on investment (ROI) remains poorly understood. Addressing this gap, this research presents findings from a case study of a Systems Engineering (SE) team conducting the preliminary design process for post‐produc …

27.08.2026journal-article

Artificial Intelligence Review

Agi-powered affective computing in cyber-physical-social-thinking space: framework, techniques, applications and future directions

Feifei Shi, Jingyi Yang, Zita Lifelo, Jianguo Ding, Huansheng Ning

Abstract The advent of Artificial General Intelligence (AGI) promises to revolutionize affective computing. However, current research lacks a systematic framework that accounts for the inherently cross-space nature of human emotion, where physiological states (physical space), cultural norms (social space), cognitive processes (thinking space), and digital data (cyberspace) continuously interact and shape each other. To address this gap, this paper starts by repositioning affective computing within the theory of Cy …

27.08.2026journal-article

IIARD International Journal of Banking and Finance Research

Estimated Effect of Digital Finance and Liquidity Management of Commercial Banks in Nigeria

Charles Ibebi (PhD)

The study was motivated to examine the effect of digital finance on the liquidity management of commercial banks in Nigeria. The objective was to examine the effect of digital finance on liquidity of commercial banks. Time series data were source from Central Bank of Nigeria Statistical Bulletin. Liquidity management proxy by loan to deposit ratio was used as dependent variable while Automated Teller Machine as percentage of money supply, Digital fund transfer as percentage of money supply, Mobile banking as percen …

27.08.2026journal-article

International Journal of Management, Knowledge and Learning

Citizen Science Engagement Initiatives in Kenya and Tanzania: Fostering Digital Transformation and Inclusive Knowledge Ecosystems

Kevin Muriithi Ndereba, Ukaiko Bitrus-Ojiambo, Paul Ruto, Grace Kinyanjui

This research presents the initial findings and strategic frameworks of the FOSTER Project (Fostering Digital Transformation of Science in Kenya and Tanzania), an EU-funded initiative (Erasmus+ CBHE) aimed at modernizing the research ecosystem in East Africa. The paper focuses on the promotion of Citizen Science (CS) in Sub-Saharan Africa through the Science Shop 2.0 model across Higher Education Institutions in Kenya and Tanzania. This research used a multi-phase case study and purposive sampling approach, primari …