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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
27.08.2026journal-article

BMC Medical Education

Impact of clinical case discussions in anatomy on national exam performance: a 10-year longitudinal cohort study

Fang Fang, Lan Yu, Yetao Ou, Si Zhou, Jun Ma, Yuntao Peng, Fang Liu, Junfeng Wang, Chunbo Xia, Houzhong Li, Weishan Zhang, Tan Cheng, Yu Chen, Yi Huang, Xin Li, Heng Guan

Abstract Background Traditional anatomy instruction often prioritizes structural memorization over clinical application. Although case-based learning is widely endorsed to bridge this theory-practice gap, longitudinal evidence regarding its sustained impact in foundational sciences remains limited, particularly concerning its performance over a decade amid massive enrollment expansion. Methods This 10-year longitudinal retrospective cohort study tracked seven clinical medicine cohorts (2015-2021). To maintain teach …

27.08.2026journal-article

Frontiers in Neurology

Clinical features associated with cerebrospinal fluid Epstein–Barr virus positivity in autoimmune GFAP astrocytopathy: a multicenter retrospective cohort study

Xing Mao, Qianqian Qu, Chao Quan, Haidong Lyu, Jingzi Zhangbao, Xuan Wang, Hongmei Tan, Xiang Li

Background Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP-A) is an inflammatory disorder of the central nervous system. The clinical implications of Epstein–Barr virus (EBV) sequences detected in cerebrospinal fluid (CSF) by metagenomic next-generation sequencing (mNGS) remain uncertain. Methods This multicenter retrospective cohort study enrolled 60 patients with GFAP-A screened from electronic medical records of two hospitals (Jan 2019–Dec 2025). Patients were stratified into CSF EBV-positive ( n …

27.08.2026journal-article

International Journal of Applied Chemistry

Concentrations and Health Implications of PM2.5, PM10, and Gaseous Pollutants in Communities near Ibom Power Company, Ikot Abasi, Nigeria

Ioryue Ijah Silas, Augustine Uche Abel, Idongesit Sunday Ambrose, Akpanuko Mary Emmanuel, Abah Enuwa Bridget, Macdougal Nsikak Saddie, Ekpenyong Ofofonini Ukofia

Particulate Matter (PM) exposure from ambient air has been linked to a number of ailments, and monitoring is necessary in every industrial areas or centers to identify overexposure early. This study's assessed the concentrations of PM2.5, PM10, and related gaseous pollutants in Ibom Power Company, Ikot Abasi, Nigeria, including carbon monoxide (CO), ozone (O3), and nitrogen dioxide (NO2). The concentrations of PM2.5, PM10, NO2, CO, and O3 at three chosen towns surrounding Ibom Power Company were measured using an a …

27.08.2026journal-article

Frontiers in Pediatrics

Risk factors for abnormal bone mineral density in Duchenne muscular dystrophy and the association of regular rehabilitation with bone health

Yi Chen, Shaowei Dong, Meihuan Huang, Guixiang Liu, Turong Chen, Chunming Zhou, Mingsheng Zhang

Background We investigated the prevalence and risk factors of abnormal bone mineral density (BMD) in Duchenne muscular dystrophy (DMD) and explored the potential association of regular rehabilitation with BMD. Methods A cross-sectional study including 215 boys with DMD was conducted. Multivariate logistic regression was used to identify independent predictors, and mediation analysis was performed to explore the pathway linking rehabilitation and BMD. Results Abnormal BMD was found in 62 patients (28.8%). Age was th …

27.08.2026journal-article

Frontiers in Public Health

Association of meteorological exposures with major cancer mortality in Minhang District, Shanghai: a time series study based on distributed lag non-linear models

Jiaqi Guo, Junhui Huang, Chao Xu, Shuili Xuan, Jingyi Ni, Wei Liu, Linli Chen, Yibin Zhou

Objective This study examined the associations between meteorological exposures and major cancer mortality, with a focus on exposure-lag relationships. Methods We collected daily cancer death records and weather data from Minhang District, Shanghai, 2014 to 2023. Joinpoint regression estimated annual percent changes in age-standardized cancer mortality rates. Spearman's rank correlation was employed to explore how meteorological factors related to cancer death. Finally, a distributed lag non-linear model (DLNM) eva …

27.08.2026journal-article

Frontiers in Public Health

Assessment of awareness, usage, and attitudes toward nicotine pouches in Saudi Arabia: a cross-sectional study

Hussain Khalifa Aljumah, Hassan Ali Alradhi, Mujtaba Abbas Alzuwayr, Manal Yousef Alturaifi, Maryam Ali Alamer, Mohammed Naji Albannay, Abdullah Almaqhawi

Background Nicotine pouches (NPs) are emerging smokeless nicotine products marketed as tobacco-free alternatives to traditional smokeless tobacco products. Despite their growing popularity, particularly among youth, limited research exists on their awareness, usage, and attitudes in Saudi Arabia. Objectives This study aimed to assess awareness, usage patterns, and attitudes toward NPs among adults in Saudi Arabia. Methods A cross-sectional, online survey targeting Arabic-speaking adults was conducted between 6 Marc …

27.08.2026journal-article

TEM Journal

Predictors of the Effective Implementation of Artificial Intelligence Tools in Mathematics Education of Pre-Service Primary Teachers

Dušana Babicová, Štefan Tkačik, Zlatica Huľová, Štefan Tkačik Jr, Peter Tokoš

Previous research suggests that math anxiety is common among prospective teachers, is associated with less positive attitudes toward math, and may later affect their students. At the same time, AI tools and educational podcasts appear promising for personalized support of self-study in mathematics education. The aim of this study is to establish a baseline profile of selected predictors prior to the planned implementation of an AI assistant for self-study in mathematics. Five research questions examined the relatio …

27.08.2026journal-article

Australian Health Review

Understanding Australian community members’ knowledge of concussion: a cross-sectional nationwide survey

Sara L. Whittaker, Aleksandra K. Gozt, Lisa Licciardi, Naomi Fuller, Melinda Fitzgerald, Shenane Hogg, Natasha K. Brusco

Objective This study aimed to establish current Australian community knowledge of: (i) mechanisms of concussion injury; (ii) concussion signs and symptoms; (iii) concussion response and management; (iv) pathways of seeking help for a suspected concussion; (v) recovery journey after sustaining a concussion; and (vi) community misbeliefs about concussion. Methods An online survey measured current knowledge of concussion held by the Australian community (≥18 years). Convenience sampling was used for national data coll …

27.08.2026journal-article

Wellcome Open Research

The genome sequence of the Orange Ripple Bryozoan, Schizoporella japonica Ortmann, 1890 (Cheilostomatida: Schizoporellidae)

John Bishop, Marine Biological Association Genome Acquisition Lab, Darwin Tree of Life Barcoding Collective, Wellcome Sanger Institute Tree of Life Management, Samples and Laboratory team, Wellcome Sanger Institute Scientific Operations: Sequencing Operations, Wellcome Sanger Institute Tree of Life Core Informatics team, Tree of Life Core Informatics collective, Darwin Tree of Life Consortium

We present a genome assembly from a specimen of Schizoporella japonica (Orange Ripple Bryozoan; Bryozoa; Gymnolaemata; Cheilostomatida; Schizoporellidae). The genome sequence has a total length of 255.53 megabases. Most of the assembly (99.03%) is scaffolded into 19 chromosomal pseudomolecules. The mitochondrial genome has also been assembled, with a length of 18.45 kilobases. This assembly was generated as part of the Darwin Tree of Life project, which produces genomes for eukaryotic species found in Britain and I …

27.08.2026journal-article

مجلة بيت المشورة

Beyond Infrastructure: Mapping the Gap between Digital Capability and Consumer Trust in Travel Intermediaries (2016-2025)

Doğuş Kılıçarslan

This study maps the thematic structure of the literature on digitalization in travel businesses and traces how that structure changed over a ten-year period. The aim is not only to summarize publication activity but to read the meaning patterns in study abstracts and to describe the field at the level of content. A corpus of 391 studies published between 2016 and 2025 was drawn from the Web of Science and Scopus databases. The corpus was examined with a mixed design that combines a descriptive performance analysis …

27.08.2026journal-article

Frontiers in Global Women's Health

Abdominopelvic hydatid disease during pregnancy: a systematic review of the literature

Evangelos Chinis, Kyriakos Tzanakis, George Lockett, Laura Burney Ellis, Stergios Bobotis, Georgios Geropoulos, Maria Kyrgiou, Konstantinos S. Kechagias

Objective To review the available literature on abdominopelvic cystic echinococcosis (CE) during pregnancy, focusing on clinical presentation, diagnostic approaches, management strategies, and maternal and foetal outcomes. Methods A systematic review was conducted in accordance with PRISMA guidelines. Studies reporting abdominopelvic hydatid disease in pregnant women were included without restrictions on study design or geography. Results Fifty-one studies (45 case reports and 6 case series) including 79 patients w …

27.08.2026journal-article

Clinical and Translational Medicine

PRAME promotes invasion and metastasis of salivary adenoid cystic carcinoma by regulating RARα stability via the cullin2 ubiquitin‐proteasome system

Xudong Wang, Tingyao Ma, Yixin Jing, Tianyi Li, Xi Zhao, Guohan Zhao, Ran Gao, Lu Kong, Xiaohong Chen

Abstract Background All‐trans retinoic acid (ATRA) exerts its biological functions primarily through nuclear receptors, but its therapeutic efficacy in solid tumours remains limited. This study aimed to elucidate the regulatory role of the cancer‐testis antigen PRAME in posttranslational modifications (PTMs) of the ATRA receptor RARα, and to assess its consequent impact on tumour progression in salivary adenoid cystic carcinoma (SACC). Methods Transcriptome sequencing was performed on public datasets from the Gene …

27.08.2026journal-article

Big Data & Society

Commodifying compassion in the digital age: The promise and perils of tech for good

Maha Rafi Atal, Sofie Elbæk Henriksen, Lisa Ann Richey

Digital and data-driven technologies are transforming the humanitarian and development sectors. With the promise of faster, more efficient and accurate aid delivery, these technologies are often designed and implemented in partnerships between aid organizations and private technology firms. Consequently, “Tech for Good” has emerged as a significant humanitarian domain, where Big Tech companies aspire to create innovative technological solutions to humanitarian problems and link their business interests and strategi …

27.08.2026journal-article

Responsible Enterprise Pedagogy

Fair and equitable digital literacy and technology education: addressing the education gap through social entrepreneurship

Amy Abdou, Irene van Driel, Dadi Chen

Purpose This study examines two small social enterprises – a social business and a non-profit – founded by the same entrepreneur that provide digital literacy and technology education in the Netherlands. By comparing two distinct social enterprise models and their approaches to equitable supplemental education, the paper explores the relationships among entrepreneurial logics, organizational practices and external stakeholder involvement, including the role of government. Design/methodology/approach Drawing on thre …

27.08.2026journal-article

Journal of Fish Health

Growth Performance and Pathological Responses of Tissue Culture and Local <i>Kappaphycus alvarezii</i> Seedlings in Marine Waters of Punti Village, Bima Bay, Indonesia

Alis Mukhlis, Nadirah Karimatul Ilmi, Sanca Rahmatullah, Anita Prihatini Ilyas, Ardyen Saputra

Kappaphycus alvarezii is an economically important carrageenan-producing red alga, and tissue culture has been promoted as a means of improving seedling quality and field growth performance in Indonesian seaweed farming; however, field-based evidence comparing tissue-culture and conventional (local) seedlings under commercial cultivation conditions remains limited. This study therefore compared the growth performance and disease susceptibility of tissue-culture-derived and local Kappaphycus alvarezii seedlings cult …

27.08.2026journal-article

Al Qodiri : Jurnal Pendidikan, Sosial dan Keagamaan

Mental Health from the Perspective of Positive Psychology and the Concept of Patience and Gratitude in Islam

Rudi Herianto

Mental health is increasingly understood as a multidimensional condition involving psychological functioning, meaningful relationships, positive emotions, and the ability to respond constructively to life challenges. Positive psychology provides an important framework for understanding these dimensions through human strengths, flourishing, meaning, and well-being. However, psychological perspectives alone may not fully capture the spiritual dimensions of mental health within Muslim communities. This study examines …

27.08.2026journal-article

Pilot and Feasibility Studies

The Mother Nature Programme: a single-arm mixed-methods feasibility study of a group nature-based intervention for mothers experiencing postnatal mental health difficulties and their infants

Katherine Hall, Rosa Roberts, Katrina Turner, Lucinda Stanton, Sherien Elsheikh, Christopher Barnes, Beverly Shirkey, Lucy Duggan, Paul Moran, Jonathan Evans

Abstract Background Postnatal mental health difficulties are common and often under-treated. Nature-based interventions have potential mental health benefits, but little research has focussed on their applicability postnatally. This study examined the acceptability and feasibility of delivering a co-designed, 5-week group nature-based intervention, The Mother Nature Programme (MNP), for mothers experiencing postnatal mental health difficulties and their infants, in preparation for a future trial. Methods A single-a …

27.08.2026journal-article

BMC Oral Health

Oral findings and antiresorptive therapy exposure duration in postmenopausal women with osteoporosis: a cross-sectional cohort study

Safiyye Süslü, Håvard J Haugen, Tormod Bjartveit Krüger, Bente B. Herlofson, Janne Elin Reseland, Erik Fink Eriksen

Abstract Background Oral findings are common among older adults, but it is unclear whether they vary with the duration of antiresorptive therapy (ART) exposure or relate to the severity of osteoporosis in postmenopausal women. Methods In this cross-sectional cohort ( n = 129), postmenopausal women undergoing osteoporosis assessment/follow-up were stratified by ART exposure duration: no current ART control (G1, n = 50), short ART (G2, 3–5 years; n = 39), and long ART (G3, > 5 years; n = 40). The prespecified primary …

27.08.2026journal-article

Biosensors

Artificial Intelligence in Electrochemical Sensing: A Network Evidence Map of Translational Barriers and Pathways to Point-of-Care Deployment

Muhammad Saqib, Elena I. Korotkova, Kunquan Li, Neda Firoz, Mrinal Vashisth, Amrit L. Hui, Olga I. Lipskikh, Pradip Kumar Kar

The integration of artificial intelligence (AI) and machine learning (ML) with electrochemical sensing has revolutionized analytical diagnostics by overcoming traditional limitations such as signal drift, peak overlapping, and matrix interference. However, despite the exponential growth of this field, a unified framework evaluating translational feasibility remains absent. This review critically analyzes AI/ML architectures applied to electrochemical sensors and biosensors from 2016 to 2025. To the best of our know …

27.08.2026journal-article

Materials

Antibacterial Interventions for Orthodontic Appliances; Surface Modifications, Coatings and Bulk-Incorporated Antibacterial Agents: Materials, Mechanisms and Clinical Application—A Scoping Review

Berta Furió-Alonso, Javier Gil, Danica Nikolic Jovanovic, Andreu Puigdollers-Pérez

Biofilm accumulation on orthodontic appliances is a recognized risk factor for white spot lesion formation and caries during treatment. Antibacterial surface modifications and coating strategies have been proposed as appliance-level preventive approaches. Studied interventions in the literature span true thin-film surface coatings, plasma-based and ion-implantation surface modifications, and bulk-incorporated antibacterial agents in appliance matrix materials. Yet the extent to which in vitro efficacy translates to …

27.08.2026journal-article

Journal of Plastic Surgery and Hand Surgery

Clinical outcomes of a defect-adapted strategy for free fibular great toe flaps in finger reconstruction: a retrospective series of 35 cases

Yangyang Liu, Huajian Zhou, Haoran Jiang, Jun Zhu, Renjie Li, Mingyu Jia

Background: To evaluate the clinical outcomes of a personalized surgical strategy for small-to-medium finger defects, utilizing either free dorsal toe or plantar proper digital artery flaps. Methods: We retrospectively analyzed 35 patients with finger defects (March 2021–January 2025). Patients were assigned by defect characteristics to Group A (pulp defects, n = 21; plantar proper digital artery flap) or Group B (dorsal/lateral defects, n = 14; modified dorsal toe artery flap preserving the plantar proper neurovas …

27.08.2026journal-article

Journal of the National Comprehensive Cancer Network

Fostering Improvements in Equitable Care Delivery: Insights From the Health Equity Report Card (HERC) Pilot in Academic Cancer Centers

Ashley Orr, Taneal D. Carter, Mallory Stubblebine, Heather McKee Hurwitz, Tiffany Go, Leticia Mercado, Darryl Outlaw, Elizabeth Bouchard, Levent Dumenci, Crystal S. Denlinger, Alyssa A. Schatz

Background: The Health Equity Report Card (HERC) was developed to support institutions in measuring equitable care practices and implementing improvement efforts. An objective of this study was to determine whether academic cancer centers can use their baseline HERC scores to identify institution-specific strategies to improve equitable care delivery. Methods: This quality improvement study collected quantitative and qualitative data from 5 NCCN Member Institutions about their quality improvement efforts in respons …

27.08.2026journal-article

Clinical Cancer Research

Focused Ultrasound-Enhanced Drug Delivery to Brain Tumors: Quantitative and Translational Insights from CNS Physiologically Based Pharmacokinetic Modeling

Andrew Wu, Charuka Wickramasinghe, Yuanyuan Jiang, Xun Bao, Jing Li

Abstract Purpose: Successful clinical translation of focused ultrasound (FUS)-induced blood-brain barrier (BBB) opening strategy to brain cancer therapy has been hindered by limited quantitative understanding of CNS pharmacokinetics. Using a physiologically based pharmacokinetic (PBPK) modeling framework, this study aimed to quantitatively characterize FUS-modulated CNS pharmacokinetics and identify key determinants of potential clinical benefits. Experimental Design: A previously validated 9-compartment CNS PBPK m …

27.08.2026journal-article

Ege Eğitim Dergisi

In-Service English Teachers' Attitudes toward Artificial Intelligence in Education

Pelin Derinalp

The rapid advancement of technology requires teachers to adapt to this change. Artificial intelligence (AI) is increasingly being used in education and is gaining influence. Therefore, examining teachers' attitudes toward AI is important for the effective integration of technology. This study investigates the attitudes of English teachers in Türkiye toward AI. Using qualitative descriptive research design, participants were first asked to provide written definitions of AI. Subsequently, four focus group discussions …