Frag' FlorenceEvidenz. Klar. Anwendbar.
Uhr 7/8Sources Journal Tree
Easy Demo

Florence Themenbrowser · Therapie & Reha · Seite 81

Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

Themen erkunden

Aktuelle Forschung nach Fachgebiet

24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
17.08.2026journal-article

Minerva

Refractory Multisystem Gorham-Stout Syndrome: Robotic Approach, Vascular Microsurgery, and Immunological Therapy

Kerly Lilibeth Cabezas Estrada, Paula Estefania Gaibor Ramos, Diego Freddy Garcia Rivera, Giovanna Estefania Ramos Onate

Gorham-Stout syndrome (GSS) is a rare lymphatic malformation with fewer than 400 documented cases, characterized by progressive osteolysis and multisystem involvement. Its refractory management to conventional therapies represents a significant clinical challenge. This systematic review, following PRISMA 2020, synthesizes current evidence on pathophysiological mechanisms, diagnosis, and emerging therapeutic strategies for refractory multisystem GSS, with emphasis on robotic surgery, vascular microsurgery, and immun …

17.08.2026journal-article

Frontiers in Public Health

Patients’ perspectives on pulmonary rehabilitation for pulmonary hypertension in high-altitude areas: a mixed-methods study

Wenrui Li, Xiangqun Ke, Jinpeng Ma, Rui Jin, Haiyu Zhao, Yu Zheng, Xiaozhou Wang, Yaping Zeng, Mingwei Chen, Tinghua Hu

Background Chronic hypoxia at high altitudes worsens pulmonary hypertension (PH), leading to earlier symptom onset, more frequent exacerbations, and diminished quality of life. While pulmonary rehabilitation (PR) is known to enhance exercise capacity and ease breathlessness, implementing it in high-altitude settings presents a range of multifaceted challenges. Research capturing patients’ firsthand experiences with PR in these settings is largely absent. This study explored how PH patients in high-altitude areas cu …

17.08.2026journal-article

World Journal of Surgery

Effect of Prophylactic Incisional Negative Pressure Wound Therapy on Surgical Site Infection After Emergency Laparotomy: An Updated Meta‐Analysis With Trial Sequential Analysis

Ana Luíza Rocha Soares Menegat, Brenda Luana Rocha Soares Menegat, Sara Bravin, Jacopo Lin, Henrique Wiederkehr

ABSTRACT Introduction Patients undergoing emergency laparotomy are at high risk of surgical site infections (SSI), which contribute substantially to postoperative morbidity. Incisional negative pressure wound therapy (iNPWT) has been shown to reduce the incidence of SSI following elective surgery, however, its effectiveness in the emergency setting remains uncertain. Therefore, we conducted a systematic review and meta‐analysis to evaluate the effectiveness of iNPWT in reducing SSI after emergency laparotomy. Metho …

17.08.2026journal-article

Catheterization and Cardiovascular Interventions

A Staged Revascularization Strategy for Chronic Limb‐Threatening Ischemia With GLASS Stage IMP2 Disease: Distal Bypass Following Infrapopliteal/Pedal Endovascular Therapy

Yoshihiko Tsuji, Taku Toyoshima, Osamu Iida, Ikuro Kitano

ABSTRACT Patients with chronic limb‐threatening ischemia (CLTI) and Global Limb Anatomic Staging System (GLASS) stage IMP2 disease often lack suitable inframalleolar target arteries for distal bypass on conventional imaging, rendering them technically ungraftable. We adopted a staged revascularization strategy consisting of initial infrapopliteal/pedal endovascular therapy (EVT) to establish graftable pedal arteries, followed by distal bypass using autologous saphenous vein grafts before restenosis or reocclusion o …

17.08.2026journal-article

PLOS One

EMPATH protocol: Randomized, double-blind trial of an Engaging and Mobile Prism Adaptation Treatment for spatial neglect in Home and rehabilitation settings

Catrina MacPhee, Gail Eskes, Sean P. Mackinnon, Anne Sophie Champod

Background Spatial neglect is a common attentional condition post-stroke linked to poor rehabilitation outcomes. Prism adaptation, though a promising intervention, is not yet widely used clinically due to various barriers to its implementation, including limited accessibility, the repetitive nature of the therapy, and the need for specialized equipment. This protocol aims to examine the effectiveness, feasibility, and acceptability of an engaging, mobile, computerized prism adaptation procedure (Peg-the-Mole) for t …

17.08.2026journal-article

Anaesthesiology Intensive Therapy

Comparison of kinemyography and electromyography during onset of and recovery from non-depolarising neuromuscular blockade: prospective observational study

Michal Kalina, Jan Beneš, Olha Litvina, Vladimír Černý

Background Quantitative neuromuscular monitoring is essential for the safe management of neuromuscular blockade. Although electromyography (EMG) is increasingly regarded as a reference technique, kinemyography (KMG) remains widely used in clinical practice; however, clinically relevant differences between these modalities during onset and recovery of neuromuscular blockade are not fully understood. Methods In this prospective observational study, adult patients undergoing general anaesthesia with non-depolarising n …

17.08.2026journal-article

British Journal of Occupational Therapy

Factors influencing the level of creative participation of nursing home residents: An observational cohort study

Nicola Ann Plastow, Elzaan Blaauw, Kayla Burger, Tyla van Schalkwyk, Fatima Moos, Shivani Naidoo, Fiona Smith, Monique de Wit

Introduction: The Vona du Toit Model of Creative Ability (VdT MOCA) is a widely used theoretical framework that has the potential to improve meaningful participation among nursing home residents. No published research evidence supports its use in occupational therapy with older people. Method: We used a quantitative cross-sectional observational cohort study design to identify factors influencing the level of creative participation of 30 nursing home residents ( M age = 87.2, SD = 8.42) in South Africa, using the C …

17.08.2026journal-article

Journal of Computational and Cognitive Engineering

IoT-Controlled EEG Monitoring and Decision Support System for Autism Therapy Using Signal Analysis and Embedded Processing

Melinda Melinda, Nizam Albar, Yuwaldi Away, Karlisa Priandana, Prima Dewi Purnamasari, Muhammad Saifullah Nur, Nurlida Basir, Syahrul Gazali

Autism spectrum disorder (ASD) is associated with irregular neural activity that complicates therapy planning when based solely on behavioral observation. This study introduces an Internet of Things (IoT)-based electroencephalography (EEG) analysis system designed to support real-time therapy recommendations for children with ASD. EEG signals were processed using the fast Fourier transform for noise reduction and evaluated through power spectrum density (PSD) using Welch's method to characterize spectral patterns. …

17.08.2026journal-article

World Journal of Urology

Percussion, diuresis, and inversion therapy can facilitate lower renal pole stone passage after extracorporeal shock wave lithotripsy and retrograde intrarenal surgery? A systematic review and meta-analysis of randomized controlled trials

Luiz G. S. Gimenez, Giovanni S. Marchini, Fabio C. M. Torricelli, Alexandre Danilovic, Carlos A. Batagello, Fabio C. Vicentini, William C. Nahas, Eduardo Mazzucchi

Abstract Purpose Patients with lower pole stones (LPS) present a significant challenge for urologists because of the increased likelihood of residual fragments and recurrence following extracorporeal shockwave lithotripsy (ESWL) and retrograde intrarenal surgery (RIRS). Although percussion, diuresis, and inversion (PDI) therapy has demonstrated potential for enhancing the stone-free rate (SFR) in these patients, its application remains a topic of debate. Consequently, our objective was to conduct a systematic revie …

17.08.2026journal-article

Advanced Materials

Thermosensitive Liposome‐Loaded Hydrogels Enable Mechano‐Chemical Cascade Therapy for Promoting Angiogenesis

Meng Lei, Zhaoxinru Liu, Yizhou Xie, Xuewen Chen, Yaohui Wang, Jichang Wang, Feng Xu, Zhao Wei

ABSTRACT Pharmacological activation of selective biophysical or chemical signaling pathways is known to regulate angiogenesis; however, whether these cues can be modulated in a temporally coordinated, cascade‐like manner to generate stable and functional vascular networks remains unclear, particularly in the ischemic microenvironment. Here, we demonstrate a mechanochemical cascade in which TRPV4 (transient receptor potential vanilloid 4)‐mediated mechanosensing initiates endothelial activation, followed by platelet …

17.08.2026journal-article

Multiple Sclerosis Journal

Automated speech analysis reveals progressive linguistic changes associated with subsequent gray matter loss in multiple sclerosis

Martin Šubert, Tereza Tykalová, Michal Novotný, Barbora Srpová, Jiří Motýl, Jan Krásenský, Matěj Kudrna, Manuela Vaněčková, Dana Horáková, Tomáš Uher, Jan Rusz

Background: The utility of high-level linguistic analysis for longitudinal monitoring of multiple sclerosis (MS) and its relationship with progressive brain volume loss remains largely unexplored. Objective: To characterize longitudinal changes in lexical and syntactic features in MS and determine whether linguistic alterations are associated with subsequent brain volume loss. Methods: Ninety-seven patients with MS and 80 age- and sex-matched healthy controls completed story narration tasks at baseline and 2-year f …

17.08.2026journal-article

Pediatrics

Early Antiviral Therapy in Pediatric Outpatients and Risk of Influenza-Related Hospitalization

Ya-Ning Huang, Chia-Jung Chang, Yu-Ling Dai, Yen-Hsin Kung, Ching-Ying Huang, Daniel Tsung-Ning Huang, Chien-Yu Lin, Lung Chang, Wan-Yu Lin, Luan-Yin Chang, Chi-Tai Fang, Hsin Chi, Nan-Chang Chiu, Fu-Yuan Huang

OBJECTIVES Evidence on the effectiveness of antiviral therapy in preventing influenza-related severe illness and hospitalization among children remains limited. We hypothesized that early administration of antiviral therapy within 48 hours of symptom onset would significantly reduce the risk of subsequent influenza-related severe illness and hospitalization. METHODS This multicenter, age- and season-matched, retrospective case-control study included all pediatric outpatients with laboratory-confirmed influenza who …

17.08.2026journal-article

World Journal of Otorhinolaryngology - Head and Neck Surgery

Speech Recognition Deficits in Presbyacusis: Links to Cortical Structural and Functional Alterations

Xiao‐Qian Ren, Lan Lan, Xiao‐Long Li, Xiang‐Bing Bian, Jin Li, Lan Yu, Dan‐Yang Li, Xin Lou, Qiu‐Ju Wang

ABSTRACT Objective To characterize speech recognition in presbyacusis and its associated neurophysiological and cortical structural features, and to explore structure‐function‐behavior relationships within the presbyacusis phenotype. Methods Thirty elderly patients with presbyacusis(HI) and thirty‐three healthy young controls(NH) completed a behavioral task involving Putonghua monosyllabic word recognition. Additionally, mismatch negativity (MMN) responses using the oddball paradigm to assess neurophysiological sen …

17.08.2026journal-article

Cells

A Novel Chorioallantoic Membrane (CAM) Setup to Investigate Angiogenic Effects of Extracorporeal Shock Wave Therapy (ESWT)

Lorenz Faihs, Jonas Flatscher, Cyrill Slezak, Bardia Firouz, Nassim Ghaffari Tabrizi-Wizsy, Kurt Schicho, Paul Slezak, Peter Dungel

Extracorporeal shock wave therapy (ESWT) is a well-known biophysical therapy that offers several beneficial effects, including a presumed increase in the growth of blood vessels. The chorioallantoic membrane (CAM) assay is a well-established in vivo model for studying angiogenesis. The aim of this study was to develop an experimental setup to apply ESWT to CAM in a three-step process and investigate the vascular response. First, we conducted virtual simulations of various shock-wave application setups to CAM and su …

17.08.2026journal-article

Frontiers in Psychology

Sustaining physical activity following participation in a joint pain exercise and education rehabilitation programme; a qualitative longitudinal study

Panayiotis Michael, Sheree A. McCormick, Jenny Alexanders, Aidan Quinn Innes, Amy Elizabeth Harwood, Francis Fatoye, Patrick Doherty, Nigel Timothy Cable, Davina Deniszczyc, Gillian Yeowell

Background Musculoskeletal conditions are leading contributors to global disability and place a significant economic burden on health systems. Optimal physical activity is a key recommended strategy for managing musculoskeletal conditions, yet many individuals struggle to sustain activity levels following the completion of exercise rehabilitation programmes. Identifying and understanding the factors that influence sustained physical activity may aid intervention design and benefit future patients. The aim of the st …

17.08.2026journal-article

Journal of Public Health and Primary Care

Tuberculosis Preventive Therapy in the Era of Primary Drug Resistance: A Primum Non Nocere Reappraisal

Sunil Kumar Raina

Abstract The assumption that anti-TB drugs function purely as bactericidal agents, with immune function as a passive benefit, reflects neither the known pharmacology of these compounds nor the dynamic biology of the latent state. Together, these realities invoke the oldest and most fundamental principle of medical ethics: primum non nocere; first, do no harm. It is the argument of this paper that TPT, as currently deployed in high-resistance settings, may, in a biologically definable and clinically significant subs …

17.08.2026journal-article

American Journal of Physiology-Cell Physiology

Combination therapy of RAS inhibition and glucagon-like peptide-1 receptor agonist improves a marker of kidney fibrosis in people with type 2 diabetes

Alexandra L. Møller, Stefanie Thöni, Felix Keller, Samir Sharifli, Federica Genovese, Morten Karsdal, Daniel G. K. Rasmussen, Gert Mayer

In type 2 diabetes (T2D), kidney fibrosis drives the progression of chronic kidney disease (CKD) and kidney failure. Lower urinary levels of collagen type III degradation (C3M), a biomarker of extracellular matrix (ECM) turnover, have been associated with CKD progression. We investigated the effect of combination therapy with renin-angiotensin system inhibition (RASi) and glucagon-like peptide-1 receptor agonist (GLP-1 RA) on urinary C3M levels in people with T2D. Urinary C3M was measured using the nordicC3M™ ELISA …

17.08.2026journal-article

National Science Review

Muco-infiltrating prodrug coacervates with prolonged colonic retention enhance IBD-associated depression therapy

Fengming Tan, Bo Yi, Lizhi Wang, Kaixin Guan, Jinhong Qin, Mingxin Lin, Weitong Huang, Sirong Chen, Xiayi Xu, Pengchao Zhao, Liming Bian

Abstract Oral delivery of small-molecule drugs to the distal intestine is often hindered by short colonic retention, a key requirement for ensuring sustained colonic drug availability. Herein, we developed a library of minimalist, muco-infiltrating prodrug coacervates by exploiting the interfacial physics of liquid–liquid phase separation (LLPS). By systematically tuning the length of poly(ethylene glycol) (PEG) spacer and the hydrophobicity of drug stickers in PEG–drug conjugates, we precisely modulated the molecu …

17.08.2026journal-article

Russian Journal of Skin and Venereal Diseases

Skin Microbiome in Hidradenitis Suppurativa: Current Concepts and Perspectives of Personalized Therapy

S. Alferova, Natalia P. Teplyuk, Nune O. Vartanova, Elena O. Kravtsova, Oxana A. Svitich, E. Chelobanova

Hidradenitis suppurativa (HS) is a chronic, relapsing inflammatory skin disease characterized by the formation of painful inflammatory nodules, abscesses, infiltrates, and sinus tracts, predominantly affecting intertriginous areas, including the axillary, inguinal, and anogenital regions. The disease is associated with a marked impairment in patients’ quality of life, chronic pain syndrome, the development of scarring, and frequently leads to significant social and psychological maladaptation. Despite substantial p …

17.08.2026journal-article

Journal of Civil, Construction and Environmental Engineering

Comparison of Field Tests and Methods of Rehabilitation for Flexible and Rigid Pavement Infrastructures in Egypt and Saudi Arabia: A Comprehensive Review

Mostafa Hassan

Roads are a vital infrastructure that links cities and countries and facilitates trade between countries. The impact of severe climate change is increasing significantly all over the world and influences its effect on vital roads with respect to changes in temperature that induce significant thermal stresses, relative humidity, and extreme floods these days. Different mix designs, field tests, and materials utilized for flexible (Asphalt) and rigid pavement (Concrete) in Egypt and Saudi Arabia will be discussed in …

17.08.2026journal-article

Teaching and Learning in Communication Sciences & Disorders

Targeted Interprofessional Education (IPE) Curriculum for First-Year Speech-Language Pathology (SLP) Graduate Students

Cody Marie Busch

ASHA requires that SLP graduate programs facilitate opportunities for interprofessional collaborative practice (IPCP). Research suggests that IPCP initiatives should be integrated throughout the curriculum, rather than isolated interprofessional education (IPE) experiences. 15 first-year SLP graduate students participated in a year-long IPE curriculum focused on the IPEC Core Competencies. Quantitative and qualitative data revealed improved perception of IPCP and appreciation of opportunities to interact with other …

17.08.2026journal-article

Journal of Applied Microbiology

Evaluation of Sequential Phage-Antibiotic Therapy Reveals Enhanced Biofilm Control with Meropenem and Colistin in Clinical MDR Hypervirulent Klebsiella pneumoniae Strain

Ramya Juliet, Madhumathi Irulappan, Balaji Veeraraghavan, Ramesh Nachimuthu

Abstract Aims The convergence of multidrug resistance and hypervirulence in Klebsiella pneumoniae (MDR-HvKp) has narrowed treatment options. Despite growing interest in phage-antibiotic synergy (PAS), this study evaluates the underexplored combinatorial effects of phage and antibiotics, including drug-specific interactions and sequence dependency, against the biofilm-forming MDR-HvKp clinical strain. Methods and Results A T5-like Klebsiella bacteriophage, Round, within the genus Webervirus, was therapeutically and …

17.08.2026journal-article

Journal of Oral Rehabilitation

Eccentric Occlusal Loads Remodel the Dentoalveolar and Temporomandibular Biomechanical Unit in Rats

Haochen Ci, Umama Ali, Zhiyuan Yang, Ayush Bakandi, Nhu Huynh, Christine Nguyen, Brandon Lee, Youngho Seo, Robert Flavell, Alireza Hatamifar, Rishi J. Gupta, Rebeka Silva, Yongmei Wang, Bo Wang, Sunita P. Ho

ABSTRACT Background Altered occlusal mechanics are critical regulators of the structure and function of the dentoalveolar and temporomandibular joints (DAJ, TMJ); however, the multiscale biological and mechanical consequences of sustained occlusal rise on the TMJ are not understood. Objective This study establishes a proof‐of‐concept for using an occlusal rise (OR) to investigate how the resulting chronic eccentric loading influences the DAJ and TMJ across mechanical, structural, and metabolic domains. Methods Rats …

17.08.2026journal-article

PLOS One

Occupational safety and health risks among plumbers: A qualitative study of workplace hazards, safety practices, and system-level gaps in Texas

Mary Conger, Avishek Choudhury

Background The plumbing trade exposes workers to ongoing workplace hazards that pose significant health risks. This issue is well known but remains unresolved. A key question remains: why have current safety measures, such as training programs, regulatory standards, and personal protective equipment (PPE) requirements, failed to reduce injury rates or significantly improve safety in the plumbing field. Objectives Despite well-documented hazards in plumbing work, qualitative research examining why existing safety me …