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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
11.08.2026journal-article

Psychogeriatrics

Individual and Institutional Factors Associated With the Quality of Life of Portuguese Older Adults Living in Nursing Homes

Bartolomeu Alves, Micaela Gonçalves, Ana Rute Costa, Rui Passadouro, Alexandra Lopes, Ana Henriques

ABSTRACT Purpose To identify individual and institutional characteristics that are associated with the quality of life (QoL) of institutionalized older adults aged 60 and above in Portuguese nursing homes. Methods This cross‐sectional study involved 22 nursing homes from the central region of Portugal and a total of 213 institutionalized older adults aged 60 or older without cognitive impairment, selected through random cluster sampling. Participants were interviewed using a structured questionnaire to collect data …

11.08.2026journal-article

International Journal of Behavioral Development

Older Adults’ Everyday Perceptions of Ageism: The Role of Television and Social Media

Juhyeong Lee, Yoonseok Choi, Klaus Rothermund, Christiane A. Hoppmann

While ageism experiences are associated with reduced well-being among older adults, the contexts in which they encounter ageism remain underexamined. This study investigated everyday contexts of perceived ageism among older adults in Canada, with a particular focus on TV and social media usage. We analyzed up to 14 days of evening diaries from 111 individuals aged 50 and above living in Canada (Age: M = 71.27 years, SD = 9.02; 75% female). Participants reported their daily TV viewing, social media screen time, purp …

11.08.2026journal-article

Journal of Laparoendoscopic & Advanced Surgical Techniques

Age-Stratified Outcomes of Off-Clamp Robot-Assisted Partial Nephrectomy: A Comparison of Patients Younger Than 65 Years and Those Aged 65 Years or Older

Oh Jun Yun, Jun-Koo Kang, Sang Hyub Lee, Yun-Sok Ha, Seock Hwan Choi, Bum Soo Kim, Hyun Tae Kim, Tae-Hwan Kim, Eun Sang Yoo, Tae Gyun Kwon, Jae-Wook Chung

Background: Evidence for completely off-clamp robot-assisted partial nephrectomy (RAPN) in older patients is limited. We compared age-stratified short-term outcomes. Methods: We reviewed 146 consecutive patients who underwent off-clamp RAPN between June 2022 and March 2026: 99 were aged <65 years and 47 were aged ≥65 years. Outcomes included perioperative measures, 90-day major complications, postoperative day 1 (POD1) hemoglobin (Hb) decline, estimated glomerular filtration rate (eGFR) change, and surgical margin …

11.08.2026journal-article

Journal of Speech, Language, and Hearing Research

Relationship Between Dynamic Pitch Sensitivity and Vocal Emotion Recognition in Different Listening Conditions in Older Listeners

Benjamin T. Amartey, Monita Chatterjee, Pamela Souza

Purpose: This study examined the relationship between sensitivity to dynamic pitch (i.e., perception of intonation) and vocal emotion recognition in older adults under different listening conditions. We hypothesized that better dynamic pitch sensitivity would be positively associated with accurate recognition of vocal emotions, regardless of age or listening context. Method: We conducted two related studies. In Study 1, 32 listeners (ages 55–88 years) completed a pitch direction identification task assessing dynami …

11.08.2026journal-article

International Journal of Molecular Sciences

Theranostic Innovative Strategies for Brain Diseases: New Insights on Neurovascular Unit-Associated Pathological Changes in Neurodegenerative Disorders and Aging

Giulia Terribile, Matilda Pedrinazzi, Irene Frigerio, Giulio Sancini, Romina Combi

Central nervous system (CNS) disorders represent a significant healthcare challenge, with aging as the primary risk factor. Current clinical management remains predominantly symptomatic, as late-stage diagnosis and the blood–brain barrier (BBB) limit therapeutic efficacy. This review synthesizes emerging innovations in neurotheranostics—integrated diagnostic and therapeutic platforms—focusing on the neurovascular unit (NVU) as a central pathogenic driver and target. Evidence indicates that NVU and BBB dysfunction a …

11.08.2026journal-article

Research and Theory for Nursing Practice

Supporting Youth Aging Out of Foster Care: A Theory-Guided Integrative Review Using Meleis’s Transition Theory

Faith A. Tissot

Background: Annually, approximately 170,000 persons in the United States transition from foster care to independent adulthood, often with an abrupt discontinuation of essential support services. The immediate loss of vital supports often triggers a cascade of instability that flows into the financial, guardianship, and safety sectors. Purpose: The purpose of this review was to examine the small body of literature that explicitly applies Meleis’s Transition Theory to the experiences of individuals aging out of foste …

11.08.2026journal-article

North American Journal of Aquaculture

Multiple, low-dose copper sulfate pentahydrate treatment effects on water quality and bacterial, phytoplankton, and zooplankton communities in catfish aquaculture ponds

Bradley M Richardson, Charles C Mischke, Caitlin E Older, Monica L Wood, Cynthia Ware, Ambika Tiwari, Manoj Chandy Koshy, John W Lowe, Geoffrey C Waldbieser, Matt J Griffin, David J Wise

Abstract Objective In U.S. catfish aquaculture, copper sulfate pentahydrate (CSP; CuSO4·5H2O) is used for a wide variety of applications, including the control of blue-green algae, pathogenic bacteria, and parasite hosts. However, information on the pondwide effects of multiple low-dose treatments is lacking. Herein, the influence of repeated, low CSP doses (0.5, 1.0, and 1.5 mg/L) on water quality, phytoplankton, zooplankton, microbial populations, and fish production were evaluated. Methods In March 2022, experim …

11.08.2026journal-article

Journal of Health Services Research & Policy

From healthcare encounters to policy: Patient and stakeholder perspectives on how stigma undermines care for people with substance use disorders and multiple disadvantages

Nikolaos Mylonas, Stephen J. Kaar

Objectives Stigma is a well-documented barrier to care for people with substance use disorders (SUDs), but little is known about how it affects individuals with SUDs who also experience multiple disadvantages such as homelessness, poverty and unmet health care needs. This article explores how stigma is experienced by service users, staff, and system-level stakeholders of outreach services tailored to this cohort, and how it shapes interactions with health care services, treatment engagement, and service implementat …

11.08.2026journal-article

Evaluation & the Health Professions

Development and Validation of the ReTos Scale as a Support Tool for Fall Risk Assessment in a Large Sample of Older Italian Inpatients

Laura Rasero, Paolo Iovino, Angela Brandi, Monica Simonetti, Riccardo Tartaglia, Tommaso Bellandi

Aim of this study was to develop and evaluate the validity and reliability of the ReTos (Regione Toscana) scale for identifying older inpatients at risk of falls. 15,159 inpatients aged ≥65 years from 41 Italian hospitals were enrolled with six-month follow-up. Items were generated through literature review and expert consensus. Content validity was assessed by a multidisciplinary panel. Exploratory factor analysis (EFA) examined dimensionality. Internal consistency was estimated using McDonald’s Omega. Criterion-r …

11.08.2026journal-article

Quality in Sport

Resistance Training and Dementia Risk: A Narrative Review

Mikołaj Brzusek, Anna Mazur, Natalia Zięba, Dominik Tarczyński, Mateusz Czech, Miłosz Cisłak, Michał Chojęta, Jakub Czmok, Dominika Ciesielska, Katarzyna Kociuba

Background: One of the key challenges of modern public health is the progressive aging of populations, which consequently leads to an increase in the prevalence of numerous conditions, including dementia. These diseases pose a major social problem, driving the search for effective methods to prevent them or mitigate their severity. One preventive measure recommended by the WHO is resistance training. Research indicates that it exerts a multi-level positive effect on dementia risk factors, thereby reducing the overa …

11.08.2026journal-article

Transportation Research Record: Journal of the Transportation Research Board

Evaluation of Practical Asphalt Mixtures Long-Term Aging Protocols for Balanced Mix Design in Quality Assurance Specifications

Ahmed Hemida, Louay N. Mohammad, Samuel B. Cooper, M. Mojammel Hoque

The Louisiana Department of Transportation and Development (LDOTD) incorporated laboratory performance testing in a balanced mix design (BMD) framework in its 2016 Standard Specifications for Roads and Bridges for all travel-lane mixtures. BMD procedures include loaded wheel tracking (LWT, AASHTO T 324) and semicircular bend (SCB, ASTM D8044) tests for job mix formula approval. However, the 85°C/5 days long-term aging (LTA) requirement for SCB specimens has limited BMD use in quality assurance (QA). Here, practical …

11.08.2026journal-article

Journal of Parkinson’s Disease

Cognitive-behavioral therapy in people with Parkinson's disease and caregivers: A mixed method systematic review on clinical applications and therapeutic outcomes

Francesca Proietti, Simone Migliore, Chiara Longo, Francesca Lea Saibene, Giuseppe Curcio, Maria Chiara Malaguti, Mario Meloni, Edoardo Bianchini, Massimo Marano

Background Cognitive behavioral therapy (CBT) has emerged as a promising intervention in Parkinson's disease (PD), although the available evidence remains heterogeneous in design and quality. Objective The present mixed method systematic review aims to synthesize the evidence on CBT in people with PD (PwPD) and caregivers, focusing on clinical applications and therapeutic outcomes across symptom domains. Methods A systematic search of PubMed, Web of Science, Scopus and Cochrane databases was conducted for studies p …

11.08.2026journal-article

Journal of Proteome Research

Urine and Serum Proteome and Lipidome Analysis of Naturally Aging Feline Species

Punyatoya Panda, Rodrigo Mohallem, Rita de Kassia Rodrigues Bezerra Filgueira, Niwako Ogata, Uma K. Aryal

Abstract Aging in companion animals such as cats closely relates to human aging in environmental exposures and disease manifestation, providing a valuable model for identifying biomarkers of age-associated decline. This study provides a combined proteomic and lipidomic analysis of serum and urine from naturally aging domestic cats aged 3.8–16 years, grouped as adult, old, and senior, to identify age-related molecular changes across biofluids. Label-free quantitative proteomics identified 901 urinary and 238 serum p …

11.08.2026journal-article

Journal of Health Psychology

A comparative study of vape, pouch, and cigarette related beliefs and behaviors and their determinants in young Finnish people

Daniel J. Phipps, Keegan Knittle, Martin S. Hagger, Kyra Hamilton

Youth vaping and nicotine pouch use have risen as cigarette smoking declines, yet comparative evidence on their determinants remains limited. This study examined how socio-structural factors and an extended theory of planned behavior model predict nicotine vaping, nicotine pouch use, and cigarette smoking among Finnish youth. A survey of 1194 youth aged 15–25 assessed socioeconomic status, health literacy, theory of planned behavior belief-based constructs, intentions, behavior, and addiction. Nicotine pouches were …

11.08.2026journal-article

Frontiers in Aging Neuroscience

Plasma multi-miRNA models classify Alzheimer’s, Parkinson’s, and Lewy body dementia

Ursula S. Sandau, Jack T. Wiedrick, Trevor J. McFarland, Dora Yearout, Cyrus P. Zabetian, Shu-Ching Hu, Debby W. Tsuang, Joseph F. Quinn, Julie A. Saugstad

Introduction Differentiating Alzheimer’s disease (AD) from both Parkinson’s disease (PD) and Lewy body dementia (DLB) is difficult due to their clinical similarities. Plasma biomarkers offer an alternative to neuroimaging and cerebrospinal fluid analysis; however, there are limitations with respect to differential diagnosis of AD, PD, and DLB with current clinical assays. Methods Here we used machine learning to assess plasma miRNAs for their specificity in diagnosing AD vs. PD, and DLB. Our multi-center study assa …

11.08.2026journal-article

The British Journal of Social Work

‘I wasn’t aware what it was I was suffering from’: An evaluation of the impacts of the ‘empty nest’ on older adults and the potential implications for social work

Denise Turner

Abstract This article reports findings from a pilot study exploring the experiences of the ‘empty nest’ or ‘post-parental life phase’ among older adults in the UK, which highlight implications for social work practice. Drawing on a survey of fifty-three respondents, predominantly aged 60 and over, the study situates the empty nest within a life course framework, recognizing how midlife transitions may shape wellbeing in later life. The research is located within the context of a rapidly ageing UK population and inc …

11.08.2026journal-article

Buildings

Environmental Factors, Spatial Behavior, and Unit-Based Design in Dementia Care: A Case Study of Three Long-Term Care Facilities in Xi’an, China

Dian Zhou, Pengwen Wang

Older adults with dementia in long-term care facilities often become lost, enter unintended rooms, and develop greater dependence on care staff as a result of visuospatial impairment. However, existing dementia-friendly design studies have rarely distinguished among residents with different cognitive impairment characteristics. This exploratory cross-sectional study investigated 76 older adults with dementia and visuospatial impairment in three long-term care facilities in Xi’an, China. Neuropsychological assessmen …

11.08.2026journal-article

npj Aging

Social experiences and mortality risk: mediating roles of epigenetic aging, allostatic load, and health status

Holly G. Prigerson, Abigail J. Maciejewski, Paul K. Maciejewski, David Russell

Abstract Social environments affect health and longevity, yet biological pathways remain incompletely understood. Data from Midlife in the United States (MIDUS) study were used to examine whether social experiences predicted mortality and whether effects were mediated by epigenetic aging, allostatic load, and health status. Outcomes included epigenetic clocks (e.g., GrimAgeV2), allostatic load (e.g., immune/inflammatory biomarkers), health status, and all-cause mortality. Among 1309 participants, positive social ex …

11.08.2026journal-article

Affective Science

Amygdalar Pattern Similarity to Negative and Neutral Images, Ratings of the Images, and PET-Measured Amyloid and Tau Levels in Older Adults Without Dementia

Mingtong Liu, Lauren K. Gresham, Nikki A. Puccetti, Tobey J. Betthauser, Sterling C. Johnson, Stacey M. Schaefer

Abstract This study examines associations between brain levels of amyloid-β and tau with representational pattern similarity in amygdalar reactivity to negative and neutral images in older adults without dementia. 81 participants viewed affective images during functional magnetic resonance imaging (fMRI). Participants rated the images on valence and arousal outside the scanner. Amyloid-β and tau were measured with 11 C-Pittsburgh compound B and 18 F-MK-6240 positron emission tomography (PET) imaging. Representation …

11.08.2026journal-article

Innovation in Aging

Stepwise development of ACTIVE-AGE@home: A home-based functional exercise program for frail older adults

Emma De Keyser, Jade Tambeur, Timothy Moreels, Dimitri Vrancken, Elke De Smedt, Kathleen Willems, Wim Peersman, Dominique Van de Velde, David Beckwée, Patricia De Vriendt

Abstract Background and Objectives Older adults with frailty often experience limitations in activities of daily living (ADL), threatening independence and quality of life. Existing exercise interventions rarely balance therapeutic validity with program adherence, often lacking ADL-specific training, meaningful goal integration, and co-creation with frail older adults. This study developed and evaluated ACTIVE-AGE@home (AA@H), a home-based functional exercise program co-created with frail older adults to address th …

11.08.2026journal-article

Technology and Disability

Scoping review of home environment-person interaction theories relevant to evaluating technology for people with dementia

Catherine Henderson, Sarah Jasim, Linda Clare, Sylwia Gorska, Rachael Litherland, Martin Knapp

Background This scoping review explored theoretical frameworks that explain how assistive technology (AT), including assistive and electronic devices and home modifications, affects people with dementia and their unpaid caregivers. Objective The review aimed to identify models linking home environments to themes of independence, sense of independence, social connectedness, safety and caregiver stress. Methods We searched eight databases and Google Scholar, identifying 26 frameworks across 82 papers. The search stra …

01.09.2026journal-article

Otology & Neurotology Open

Access and Attrition Across Audiology and Cochlear Implant Care Among Older Adults with Bilateral Sensorineural Hearing Loss

Payal V. Patel, Varun Gopal, Divya Patel, Ryan G. Porter

Objective: To quantify progression through the hearing care pathway among US adults aged ≥65 years with bilateral sensorineural hearing loss (SNHL) and describe variation across geographic and community contexts. Study Design: Cross-sectional study. Setting: Epic Cosmos Database, January 1, 2021, through December 31, 2024. Patients: Adults aged ≥65 years with bilateral SNHL identified using International Classification of Diseases, Tenth Revision codes. Main Outcome(s) and Measure(s): Stage-specific unadjusted odds …

11.08.2026journal-article

Cancer Discovery

The Evolution of Polyclonal Competition in Aging Hematopoiesis

Nathaniel V. Mon Père, Francesco Terenzi, Benjamin Werner

Abstract Clonal hematopoiesis (CH)—the expansion of genetic variants in blood—is a prime example of somatic evolution. Although it often precedes malignant transformation, many aspects of this process remain unknown. We show that a model of polyclonal competition, in which selectively advantaged clones continually occur and compete, explains observed CH dynamics throughout human life. We quantify the fitness distribution and occurrence rate of clonal expansions using either variant trajectories or hematopoietic ste …

11.08.2026journal-article

Journal of Neurology

Association between mild action tremor and cognition in community dwelling older adults: results from the KORA-Age study

Gregor Kuhlenbäumer, Franziska Hopfner, Günther Deuschl, Karl-Heinz Ladwig, Birgit Linkohr, Annette Peters, Barbara Thorand, Marie-Theres Huemer

Abstract Background Essential tremor has been associated with cognitive impairment. Mild action tremor labelled physiological tremor is present in all humans. Tremor increases with age. It is unknown if mild action tremor is associated with cognitive performance in older people. Objective To test the hypothesis that mild—mostly non-pathological—action tremor is associated with reduced cognitive performance in community-dwelling older adults. Methods The Cooperative Health Research in the Region of Augsburg (KORA)-A …