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Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
10.08.2026journal-article

JAMA Network Open

Physical Fitness and All-Cause Mortality in Older Adults

Min-Chen Wu, Chen-Te Hsu, Hsiu-Tao Hsu, Chien-Chang Ho, Deng-Yau Shy, Lien-Hsi Lin, Chao-Chin Hung, Yu-Ling Chen, Che-Hsiu Chen, Yung-Po Liaw, Li-Lin Liang

Importance Regular physical activity promotes healthy aging, yet clinical risk stratification in older adults relies largely on comorbidity burden, often overlooking functional capacity. Objective fitness assessment may serve as a clinically relevant indicator of physiological reserve, but evidence from large cohorts evaluating multiple fitness domains remains limited. Objective To evaluate associations between objectively measured physical fitness across multiple domains and all-cause mortality in older adults. De …

10.08.2026journal-article

Vaccines

Association Between Herpes Zoster Vaccination and Dementia Risk: A Systematic Review and Meta-Analysis

Qing Zhang, Quanman Hu, Yaming Wei, Jun Li, Shuaiyin Chen

Background/Objectives: Dementia represents a major global health challenge, and preventive strategies remain limited. Observational studies have suggested a possible association between herpes zoster vaccination (HZV) and dementia risk, although the influence of vaccine type and dose regimen remains unclear. Methods: PubMed, Embase, and Web of Science were searched through January 2026. The primary random-effects meta-analysis included one adjusted estimate per independent study or data-source cluster. Quasi-experi …

10.08.2026journal-article

Healthcare

Power-Based Multicomponent Training, Pelvic Floor Muscle Activation Instructions, and Psychoeducation for Urinary Incontinence, Balance and Fear of Falling in Older Women (FIRE-WOMEN): Study Protocol for a Randomized Controlled Trial

Esther Ramos-Castellano, Teresa Mayordomo-Rodriguez, Ivan Chulvi-Medrano, Carlos Guillamo-Minguez, Pedro Gargallo-Bayo

Background/Objectives: Urinary incontinence (UI) and impaired balance are common geriatric syndromes that negatively affect health and quality of life in older women. However, the combined effects of power-based multicomponent training (PMT), pelvic floor muscle (PFM) activation instructions, and psychoeducational (PSY) support remain unclear. This study aims to evaluate the effects of a PMT, alone or progressively combined with PFM activation instructions and PSY support, on PFM function, UI symptoms, balance, fea …

10.08.2026journal-article

BMC Public Health

Longitudinal association between the hearing level and quality of life among older adults in south Korea: ascertaining the mediating effect of instrumental activities of daily living using latent growth and autoregressive cross-lagged models

Su Jeong Yang, Jee-Won Kim, Mina Park

Abstract Background Hearing loss is increasingly recognized as an important public health concern among older adults and is associated with decreased functional independence and quality of life. However, most previous studies have used cross-sectional designs, limiting understanding of longitudinal relationships and mediating mechanisms. This study examined the longitudinal associations among hearing level, instrumental activities of daily living, and quality of life in older adults and investigated whether instrum …

10.08.2026journal-article

Frontiers in Nutrition

Nutrition-related clinical laboratory indicators in perioperative management of geriatric hip fractures: a narrative review from risk stratification to precision intervention

Xin Xu, Ying Pan, Xuehong Zheng, Junxiang Wang, Chengcheng Zhao, Lin Xiao, Junfei Guo

Geriatric hip fracture represents a major global public health crisis that extends far beyond acute skeletal trauma, reflecting and accelerating systemic physiological decline in older adults. Malnutrition, affecting up to 46% of these patients depending on diagnostic criteria, has been established as a pivotal modifiable determinant of adverse postoperative outcomes including complications, functional decline, and mortality. Against this backdrop, nutrition-related clinical laboratory indicators have gained increa …

10.08.2026journal-article

Israel Journal of Health Policy Research

Extending geriatric care beyond traditional settings: lessons from a mobile assessment program

Zorian Radomyslsky, Dor Atias, Bar Cohen, Ali Abu-Raya, Sara Kivity, Reuma Kurz, Eduardo Schejter, Jacob Segal, Ilan Yehoshua, Ori Liran, Miri Mizrahi Reuveni, Galit Kaufman, Daniela Rahamim-Cohen, Limor Adler

Abstract Background As populations age, changing living conditions and declining self-advocacy often create barriers to essential care. Mobile Geriatric Teams (MGTs) offer a potential solution by providing assessments within a patient’s regular environment, potentially reaching underdiagnosed and undertreated individuals who struggle to access routine healthcare. The aim of this study was to evaluate the clinical impact and reach of MGTs in the Northern District of Israel. Specifically, we aimed to assess the exten …

10.08.2026journal-article

Bratislava Medical Journal

Effects of Proprioceptive Neuromuscular Facilitation-Based Reformer Pilates and Hatha Yoga on Functional Fitness, Balance, and Cognitive Performance in Older Women: A 16-Week Randomized Controlled Trial

İbrahim İhsan Arikan, Yunus Emre Yarayan, Mıhammed Özkan Turhan, Büşra Çetin, Erhan Şahin, Yusuf Buzdağli, Nouf H. Alkhamees, Sameer Badri Al-Mhanna, Marilyn Gilyana, Alexios Batrakoulis

Abstract Background Aging is associated with progressive declines in neuromuscular function, postural control, and cognitive performance, which may compromise functional independence. Mind–body exercise approaches such as Pilates and Yoga have been suggested as effective strategies to counteract these age-related changes; however, comparative evidence examining their multidimensional physiological effects remains limited. Purpose This randomized controlled trial aimed to compare the effects of PNF-supported Reforme …

10.08.2026journal-article

BMC Musculoskeletal Disorders

Incidence and risk factors for rotator cuff retear after arthroscopic rotator cuff repair in middle-aged and older patients: a systematic review and meta-analysis

Hongyu Wang, Zhiruo Jiang, Qingyun Xue, Lei Shi, Fei Wang, Haishi Zheng, Lin Wang

Abstract Background Rotator cuff retear remains a major challenge after arthroscopic rotator cuff repair (ARCR), particularly among middle-aged and older patients. This study aimed to investigate the incidence of retear and identify its associated risk factors in this patient population. Methods A single-arm proportion meta-analysis was conducted to pool the overall retear rate among studies reporting the number of retear events, total sample size, and enrollment of > 50 participants. Furthermore, meta-analyses wer …

10.08.2026journal-article

Frontiers in Aging Neuroscience

Triglyceride-glucose index is associated with cerebral small vessel disease-related motor impairment in Parkinson’s disease: a mediation analysis

Meimei Zhang, Wei Li, Yumei Zhang, Tao Feng

Background Cerebral small vessel disease (CSVD) may worsen motor and cognitive impairment in Parkinson’s disease (PD), yet whether peripheral metabolic inflammation mediates this link remains unclear. The triglyceride-glucose (TyG) index, a surrogate for insulin resistance, has been associated with CSVD and neurodegeneration. This study examined whether the TyG index statistically accounts for the association between CSVD burden and motor or cognitive deficits in PD. Methods This retrospective cross-sectional study …

10.08.2026journal-article

Materialwissenschaft und Werkstofftechnik

Influence of solution annealing and aging treatments on the electrochemical behavior of duplex stainless steel

H. N. Shridharmurthy, S. Channabasavaraj, V. Shamanth

Duplex stainless steels are broadly employed in harsh environments because of their excellent combination of mechanical strength and corrosion resistance. But, exposure to temperatures near 475 °C can trigger microstructural degradation within the ferritic phase, which results in development of chromium enriched and Iron enriched nanophases. This transformation is known to cause embrittlement and significantly diminish corrosion resistance, affecting the durability. In this experimental study, the electrochemical p …

10.08.2026journal-article

Journal of the American Geriatrics Society

A Video‐Based Support Tool to Enhance Code Status Discussions in Older Adults After Trauma: A Prospective Pilot Survey Study

Ashna S. Karpe, Mokunfayo O. Fajemisin, Stephanie Martinez Ugarte, Martin L. Blakely, Gina H. Khraish, Shreyans V. Sanghvi, Jacqueline Furbacher, Victoria E. Wagner, Kimberly A. Mankiewicz, Lillian S. Kao, Thaddeus J. Puzio

ABSTRACT Background Code status discussions (CSD) are recommended for injured older adults upon admission but often do not occur. Video‐based conversation aids can enhance these conversations, but data regarding their utility among older adults and surrogate decision makers after traumatic injury are limited. We hypothesized that a video‐based conversation aid would be perceived as acceptable and effective in improving understanding of cardiopulmonary resuscitation (CPR) among injured older adults and their surroga …

10.08.2026journal-article

Behavioral Sciences

Oral Health Status, Knowledge, Hygiene Behavior and Cognitive Function Among Older Adults in Shanghai, China

Fangzhou Ye, Xiaomin Qu, Renhao Li, Yiran Wan, Jiangyao Zhu, Junwen Yu, Xiang Qi

Cognitive impairment is a growing concern in rapidly aging societies, including China, and oral health has been proposed as a modifiable correlate of cognitive aging; however, few studies compare distinct oral health domains within the same older population or identify the subgroups in which associations are strongest. We analyzed data from 1707 community-dwelling adults aged 55+ in the 2022 Lifelong Learning and Productive Aging Survey of Shanghai (LEAP-SH) study. Cognitive problems were measured with the Ascertai …

10.08.2026journal-article

FUDMA Journal of Sciences

Prevalence and Predictors of Depression Among People Living with HIV Attending an Outpatient’s Clinic at the Nigerian Institute of Medical Research Yaba Lagos

Musa Sanni Ladan, Akeem Blessing Lateef, Ayodele Oyinlola, Imeh Christian

This study assessed the prevalence and predictors of depression among PLHIV attending the outpatient clinic of the Nigerian Institute of Medical Research (NIMR), Yaba, Lagos State. A cross-sectional research design was adopted for the study. A total of 371 adult PLHIV receiving antiretroviral therapy (ART) were selected using purposive sampling. Data were collected using a structured questionnaire which included socio-demographic characteristics, clinical and psychosocial factors, and the Patient Health Questionnai …

10.08.2026journal-article

Sexually Transmitted Infections

Trends of bacterial sexually transmitted infections with doxycycline post-exposure prophylaxis among people using pre-exposure prophylaxis for HIV

Yi-Ting Chen, Kuan-Yin Lin, Hsin-Yun Sun, Yu-Shan Huang, Wang-Da Liu, Yu-Chung Chuang, Aristine Cheng, Wang-Huei Sheng, Szu-Min Hsieh, Sung-Ching Pan, Un-In Wu, Li-Hsin Su, Yi-Ching Su, Wen-Chun Liu, Pei-Ying Wu, Yu-Zhen Luo, Hsi-Yen Chang, Ling-Ya Chen, Chien-Ching Hung

Background People using pre-exposure prophylaxis (PrEP) for HIV are at high risk of acquiring sexually transmitted infections (STIs). We aimed to assess the impact of doxycycline post-exposure prophylaxis (doxy-PEP) on the incidences of STIs among PrEP users in the real-world setting. Methods From February 2022 to November 2025, participants aged ≥18 years receiving HIV PrEP were prospectively enrolled. STI testing at baseline and follow-up included syphilis serology and multiplex real-time PCR assays for Chlamydia …

10.08.2026journal-article

Geriatrics Gerontology and Aging

Short-term, nudge-based strategies to promote physical activity in community-dwelling older adults: a pilot randomized crossover trial

Suguru Ando, Yoshihiro Yamashina, Masaki Iwamura, Yosuke Yamato, Emiko Morita, Yui Kikuchi, Wataru Nanikawa, Sho Kumabe, Yumi Fukuyama

Objective: Physical activity is essential for healthy aging. This pilot study preliminarily examined whether a short-term nudge-based behavioral intervention could influence objectively measured physical activity patterns and ensure psychological safety in community-dwelling older adults. Methods: A randomized, 2-period crossover trial was conducted with 23 community-dwelling older adults (final n = 22). Participants were assigned to intervention-control or control-intervention sequences (2 weeks each, with a 1-wee …

10.08.2026journal-article

Journal of Diabetes & Metabolic Disorders

Relationship between cardiometabolic alterations and frailty in Brazilian urban and rural older adults

Jérsica Martins Bittencourt, Sarah Aparecida Vieira Ribeiro, Débora Carvalho Ferreira, Andréia Queiroz Ribeiro

Abstract Background Frailty is a major public health concern among older adults due to its association with disability, hospitalization, and mortality. Cardiometabolic alterations are prevalent in this population and may be associated with frailty. However, evidence remains limited, particularly across different residential contexts. Objective Investigate the association between cardiometabolic alterations and pre-frailty and frailty among Brazilian older adults. Methods This cross-sectional study used data from th …

10.08.2026journal-article

International Journal of Integrated Care

The Challenges in Dementia Three-Level Prevention Services Through Integrated Care Theory: Insights from an Ethnographic Study

Taomei Zhang, Yueju Wang, Lili Li, Liping Tan, Lanshu Zhou, Huiling Li, Fengmei Tian

Background: The number of older adults living with dementia is increasing in China and worldwide. Three-level prevention is vital to delay the occurrence and development of dementia. However, the current state of these services remains suboptimal. This study aimed to explore the programs and challenges in providing dementia prevention services. Methods: A one-year ethnographic study, including semi-participatory observations and in-depth interviews, was conducted in nine settings in China from July 2022 to June 202 …

10.08.2026journal-article

Archives of Clinical Neuropsychology

57. Concussion in Older Adults: Patient Characteristics and Key Clinical Considerations for Neuropsychologists

K Courtwright, S Jennings, G Hill, M N Womble, C Dollar, P Schatz, R J Elbin

Abstract Purpose To describe the characteristics and clinical presentation of a large sample of concussed older adults, and to outline key considerations for providing specialty concussion care to this population. Method An EMR review was conducted of older adult patients (65-95years) treated between 2020 and 2026. Results A total of 196 patients presented for their first clinical visit 40.0 days following injury (SD=73.5, Range=2-736). Their average age was 72 years (SD=5.83), 69% were female, and most of the samp …

10.08.2026journal-article

Estonian Journal of Archaeology

People from Pskov in Estonian towns in the 13th century according to archaeological evidence

Andres Tvauri

The earliest towns in the territory of Estonia were founded in the 13th century. Their populations were multi-ethnic: in addition to the German merchants and artisans who dominated urban life, these towns were also inhabited by people of local origin as well as Scandinavians. The results of archaeological excavations indicate that in the second and third quarters of the 13th century, settlers of Rus’ origin from Pskov took up residence in the towns of Tartu, Viljandi, and Tallinn. In all of these towns, the Pskov …

10.08.2026journal-article

Diabetology International

Association between HbA1c status relative to individualized targets and estimated 28-day diabetes-related cost in older outpatients with diabetes: a single-center cross-sectional study

Takuya Omura, Takahiro Kamihara

Abstract Background and aims In older adults with diabetes, HbA1c below the lower limit of individualized targets may reflect intensive or potentially excessive treatment rather than favorable glycemic control. The association between this status and diabetes-related cost remains unclear. We examined the association between HbA1c status relative to individualized targets and estimated 28-day diabetes-related cost. Methods This single-center cross-sectional study included 117 outpatients aged ≥ 65 years. Patients we …

10.08.2026journal-article

European Geriatric Medicine

Development of an interprofessional education program for aspiration pneumonia care: an action research study

Tadayuki Hashimoto, Yuki Yoshimatsu, Shinichi Matsumoto, Takayuki Ando, Kiichi Enomoto, Yasuhisa Fukuzoe, Keiko Hirose, Haruki Imura, Tomohiro Matsumoto, Taiju Miyagami, Yoichi Ohtake, Mamiko Ukai, Toru Morikawa

Abstract Introduction/aim Aspiration pneumonia has evolved, with demographics shifting to predominantly frail older adults. However, despite the high healthcare impact, there is no established guideline or curriculum for the education and training of healthcare professionals in managing aspiration pneumonia in older adults. This study aimed to explore optimal educational interventions to improve holistic management of aspiration pneumonia in older adults, and to identify barriers and facilitators towards developing …

10.08.2026journal-article

ChemMedChem

Rational Design of Multifunctional Tacrine Derivatives as Candidates for the Treatment of Alzheimer and Parkinson Diseases

Eugenia Dzib, Luis Felipe Hernández‐Ayala, Silvana Silva‐Aguirre, Annia Galano

Alzheimer disease (AD) and Parkinson disease (PD) are multifactorial neurodegenerative disorders for which there is currently no therapy that prevents or slows their progress. Some drugs used to treat AD are inhibitors of acetylcholinesterase (AChE) and antagonists of N‐methyl‐D‐aspartate receptor (NMDAr), while inhibitors of catechol‐ O ‐methyltransferase (COMT) and monoamine oxidase B (MAO‐B) are used for PD. Tacrine was the first FDA (Food and Drug Administration) approved drug against AD. Although later withdra …

10.08.2026journal-article

BMC Public Health

Increasing mobility limitations among older adults in Finland: time trends and projections during 2013–2040

Marja Eliisa Holm, Jaakko Reinikainen, Päivi Sainio, Katri Sääksjärvi, Annamari Lundqvist, Jouni Lahti, Seppo Koskinen, Suvi Parikka

Abstract Background In an ageing population, physical functioning is a major public health issue. Limited information exists on how mobility limitations will change as the population ages. We assessed past and future trends in mobility limitations among the population aged 55 and older in Finland from 2013 to 2040 by age group and educational level. Methods We analyzed seven representative cross-sectional surveys in 2013, 2014, 2015, 2018, 2020, 2022, and 2024 ( n = 132,427, aged 55+). Self-reported mobility limita …