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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
28.08.2026journal-article

Journal of Biological Research - Bollettino della Società Italiana di Biologia Sperimentale

17 | The empirical use of antibiotics in hospital and territorial settings: guidelines from a Provincial Health Authority in Calabria as a tool for antimicrobial stewarship

I. Lazzaro, M. Cannataro, S. A. Mirarchi

Background. Antimicrobial stewardship implements initiatives to promote the appropriate and informed use of antibiotics, including in cases of empirical therapy, to fight multidrug-resistant pathogens. The Medical Directorate of a Provincial Health Authority in Calabria in operational collaboration with the Pharmaceutical Area, issues corporate guidelines on the empirical use of antibiotics combining hospital protocols based on microbial epidemiology (DCA N. 72/2020, Calabria Region) with territorial protocols for …

28.08.2026journal-article

Journal of Clinical Medicine

Validity, Reliability, and Responsiveness of a New Device for Measuring Pressure Pain Thresholds

Rodrigo Martín-San Agustín, Javier Guerra-Armas, Alberto Gadea-Blázquez, Elena Millán-Magariños, Borja Tronchoni-Crespo, Iván José Fuentes-Abolafio, Adrian Escriche-Escuder

Background/Objectives The evaluation of treatment effectiveness largely depends on the outcome measures used in the study. Patient-reported outcome measures (PROMs), such as the visual analog scale (VAS), and more objective measures, such as pressure pain thresholds (PPT), are commonly employed to capture pain-sensory profiles and hypoalgesic effects. The NOD is a novel digital algometer designed to assess the PPT. This study aimed to evaluate the validity, reliability, and responsiveness of the NOD algometer using …

28.08.2026journal-article

JAMA Health Forum

Administrative Burden Documented in Medicaid Care Coordination

Sanjay Basu, Aaron Baum, Kiiera Robinson, Rajaie Batniji

Importance Administrative burdens, the time, effort, and stress of navigating bureaucratic requirements, impede Medicaid beneficiaries and persist even when care is obtained, yet their frequency and patient time costs are largely invisible in claims data. Objective To measure administrative burdens documented in Medicaid care coordination notes by type, quantify the patient time costs they entail at multiple wage valuations, and characterize differences by race and ethnicity. Design, Setting, and Participants Retro …

28.08.2026journal-article

European Journal of Dental Education

Peer‐to‐Peer Education in First‐Year Dentistry: A Reciprocal Benefit for Oral Health Knowledge and Early Dental Education

Ahmet Mert Nalbantoğlu, Beyza Ballı Akgöl, R. Gözde Kırzıoğlu Ercan, Deniz Yanık Nalbantoglu, Şule Bulut, Nil Altay

ABSTRACT Introduction The study aims to evaluate the effect of peer‐to‐peer oral health education performed by dental students using three different teaching materials. Materials and Methods Seventy‐four first year students at the university, faculty of dentistry, who took part as peer educators, were divided into three groups according to the teaching material; Group I: teaching with 2D‐material (brochure), Group II: teaching with 2D‐dynamic material (video), and Group III: teaching with 3D‐material (dental model) …

28.08.2026journal-article

Geriatrics & Gerontology International

Repeated Gastrointestinal Disease Reporting and Subsequent Multidomain Health Deterioration: Longitudinal Analyses in CHARLS and ELSA

Ding Peng, Huihong Zhai

ABSTRACT Aim To examine whether repeated gastrointestinal disease reporting was associated with subsequent multidomain health deterioration and whether the direction of association was consistent across two national aging cohorts. Methods CHARLS was the primary longitudinal cohort. Participants with at least two gastrointestinal exposure assessments across waves 1–3 were classified as never, intermittent/low, or persistent/high reporting. The primary composite comprised cognitive, ADL, IADL, or depressive‐symptom d …

28.08.2026journal-article

Cochrane Evidence Synthesis and Methods

Evidence on the Relationships Between Total Fat Intake and Health Outcomes Other Than Unhealthy Weight Gain in Adults and Children: A Scoping Review

Marianne Visser, Sarah Gordon, Amanda Brand, Anel Schoonees, Celeste Naude

ABSTRACT Introduction Global guidance provides evidence‐informed recommendations on total fat intake to prevent unhealthy weight gain in adults and children, however, evidence regarding total fat intake and other health outcomes, particularly non‐communicable diseases (NCDs), also exists. This scoping review aimed to map and identify gaps in this body of evidence. Methods Four databases were searched from 2014 to 2024 for published systematic reviews (SRs), in any population, assessing the effects or associations o …

28.08.2026journal-article

International Journal of Interactive Multimedia and Artificial Intelligence

Real-time monitoring of progress on a smart learning platform

Faraon Llorens-Largo, Alberto Real-Fernandez, Patricia Compañ-Rosique, Juan Luis López-Javaloyes, Rafael Molina-Carmona

In the context of Smart Education, real-time monitoring of learning is consolidating as a key tool for both teachers and students. This approach allows teachers to early detect both high-achieving students and those facing difficulties, favoring timely pedagogical interventions that address these situations. On the other hand, the possibility for learners to visualize their progress encourages autonomous learning, as having a clear representation of their progress helps them to set personal goals and take a more ac …

28.08.2026journal-article

Pharmaceuticals

Artificial Intelligence-Guided Prioritization and Experimental Evaluation of Synergistic Target Combinations for Breast Cancer Therapy

Chunlai Feng, Qiuqi Feng, Shengnan She, Ruojing Yang, Mengru Li, Lu Gong, Mengjie Rui

Background/Objectives: Breast cancer exhibits substantial molecular heterogeneity, resulting in diverse therapeutic vulnerabilities and limiting the efficacy of single-agent therapies. Although multi-target strategies may offer improved therapeutic benefit, the systematic identification of synergistic higher-order target combinations remains challenging. This study aimed to identify and validate effective higher-order target combinations for heterogeneous breast cancer. Methods: DeepMDS, a previously developed deep …

28.08.2026journal-article

Journal of Clinical Medicine

Long-Term Mortality Following Transvenous Lead Extraction: Data from EXTRACT Registry

Sylwia Gładysz-Wańha, Michał Joniec, Wojciech Wańha, Eugeniusz Piłat, Anna Drzewiecka, Rafał Gardas, Jolanta Biernat, Andrzej Węglarzy, Danuta Łoboda, Joanna Stachańczyk, Krzysztof Stanisław Gołba

Background/Objective: The EXTRACT registry cohort of 504 patients undergoing transvenous lead extraction (TLE) has been previously reported in terms of periprocedural safety and short-term outcomes. Data on long-term mortality and its predictors in this population remain limited. The study aimed to identify risk factors for overall mortality at three years following TLE. Methods: This is a secondary, long-term follow-up analysis of the previously published EXTRACT registry cohort of 504 consecutive patients who und …

28.08.2026journal-article

Yassawi Journal of Health Sciences

CLINICAL AND DIAGNOSTIC EVALUATION OF THE INAPPROPRIATENESS OF CHEST RADIOGRAPHY WITHIN THE FIRST 24 HOURS IN CHILDREN WITH SUSPECTED PNEUMONIA

N. Shapambayev, T. Muratalieva, D. Nurbekova, B. Seitkhanova, Zh. Bagdaulet, G. Kakar, A. Zharylhan, N. Serik

Pneumonia in children remains one of the most significant problems in modern pediatrics due to its high prevalence and the risk of complications associated with delayed diagnosis. Chest radiography is widely used as a standard imaging method for confirming the diagnosis; however, its use in the early stage of the disease may have limited diagnostic value and contribute to unnecessary radiation exposure. Classically, four stages of lobar pneumonia are distinguished: congestion, red hepatization, gray hepatization, a …

28.08.2026journal-article

Yassawi Journal of Health Sciences

CIRCULAR RESECTION OF THE CENTRAL PART OF THE LARGE DIAGNOSE WITH ONCOLOGICAL STENOSIS (clinical case)

S. Ismailov, T. Akpanbetov, B. Abetayev, M. Zhanteyev, A. Aripbek

Because laryngeal stenosis leads to progressive respiratory failure, most patients with this condition require surgical treatment. Tracheal stenosis can be caused by injuries, infectious diseases, cicatricial strictures developing after tracheostomy or intubation, as well as tracheal tumors. The issue calls for improving surgical treatment methods for tracheal stenosis and refining anesthesiological intervention techniques. To improve the level of surgical treatment for tracheal stenosis by taking into account the …

28.08.2026journal-article

Current Pharmaceutical Design

Microbial Metabolites as Systemic Signaling Molecules: Integrating Metabolism, Immunity, and Organ Crosstalk in Health and Disease

Amit Kumar, Phool Chandra, Prakhar Varshney, Neetu Sachan, Mudit Kumar

Abstract: The gut microbiota produces a wide variety of metabolites that are essential for host–microbe communication and play a critical role in regulating host physiology, metabolism, and immunity. Among the most important of these metabolites are Short-Chain Fatty Acids (SCFAs), bile acid derivatives, tryptophan metabolites, polyamines, vitamins, and polyphenol-derived compounds. These bioactive metabolites regulate energy homeostasis, glucose and lipid metabolism, intestinal barrier integrity, immune signaling, …

28.08.2026journal-article

Health Research Journal of Indonesia

Upaya Peningkatan Pengetahuan Tentang Asi Ekslusif Terhadap Ibu Hamil Melalui Media Video Animasi

Windy Salsa Brilianti, Ira Titisari, Koekoeh Hardjito, Susanti Pratamaningtyas

Pemberian Air Susu Ibu (ASI) eksklusif pada bayi usia 0–6 bulan penting untuk mendukung pertumbuhan, perkembangan, dan kesehatan bayi. Rendahnya pengetahuan ibu tentang ASI eksklusif masih menjadi salah satu faktor yang memengaruhi keberhasilan pemberiannya. Penelitian ini bertujuan mengetahui pengaruh edukasi menggunakan video animasi terhadap pengetahuan ibu hamil trimester III tentang ASI eksklusif. Penelitian ini menggunakan desain pre-experimental dengan pendekatan one group pretest-posttest. Sampel berjumlah …

28.08.2026journal-article

BMC Oral Health

Effects of bone-quality configuration, effective peri-implant interface stiffness, and loading configuration on stress distribution in an ultrashort implant system: a three-dimensional finite element analysis

Betül Sümeyra Akça, Sercan Küçükkurt

Abstract Background Ultrashort implants may reduce vertical augmentation needs when residual bone height is limited, but reduced intraosseous support may increase sensitivity to eccentric loading. This full-factorial study evaluated the effects of bone-quality configuration, effective peri-implant interface stiffness, and loading configuration in a restored ultrashort implant. Methods A three-dimensional linear static finite element model included a 4.1 × 4.0-mm tissue-level implant, separate abutment and connectio …

28.08.2026journal-article

Psychological Injury and Law

Long-Term Clinical Outcomes of Symptom Overreporting and Cognitive Underperformance in Adult ADHD Assessments

Emily Raasch, Hanna Christiansen, Johanna Kneidinger, Björn Albrecht, Anselm B. M. Fuermaier

Abstract Invalid responding can bias clinical judgement, particularly in adult attention-deficit/hyperactivity disorder (ADHD), where rates of symptom overreporting and cognitive underperformance are elevated. Performance validity tests (PVTs) and symptom validity tests (SVTs) are commonly used to assess response credibility, yet their relevance for long-term clinical outcomes in ADHD remains unclear. The present study examined whether PVT and SVT scores obtained during diagnostic assessment are associated with lon …

28.08.2026journal-article

Clinical Medicine and Pharmacology

OLEOGRANULOMA OF THE BREAST AFTER SECTOR RESECTION: DIAGNOSIS PRINCIPLES AND MANAGEMENT TACTICS

Arif Guseynov, V. Fedorischev, M. D'yakov

The article discusses the problem of mammary glands (MG) oleogranulomas after sectoral resection for benign lesions. The aim of the study is to examine the statistics of postoperative MG after sectoral resection, to assess the current state of their diagnostics and management tactics.154 patients with various focal lesions of the breast were operated on. During the ultrasound of the MG 3 months after surgery, focal formations in the surgical intervention zone were revealed in 26 (16.9%) patients. Among them, oleogr …

28.08.2026journal-article

BMC Public Health

Oral HPV prevalence and its associations with HIV, oral health, immune function, and behavioral factors among youth and mothers in Nigeria: a cross-sectional study

Anil Kumar, Oluwaseun Peter, Esosa Osagie, Jianhong Chen, Paul Akhigbe, Jia Liu, Nosakhare Lawrence Idemudia, Peter Kavecky, Ozoemene Obuekwe, Fidelis Ewenitie Eki Udoko, Nicholas F. Schlecht, Yana Bromberg, Nosayaba Osazuwa-Peters, Modupe O. Coker

Abstract Background People living with HIV (PLWH) are more susceptible to human papilloma virus (HPV) infection; however, data on the oral HPV burden among youth with or without perinatal HIV exposure or infection in sub-Saharan Africa remain scarce. This study described the distribution of oral HPV and examined demographic, dental, immune and behavioral characteristics of youth and mothers across HIV exposure groups in Nigeria and explored characteristics that co-occurred with oral HPV DNA detection. Methods This …

28.08.2026journal-article

International Journal of Public Health and Medical Research

Advances in Indocyanine Green Fluorescence Imaging for Laparoscopic Hepatectomy

Hongzheng Li, Tengmeng Zhong

Indocyanine green (ICG) near-infrared fluorescence imaging enables real-time, repeatable, and radiation-free navigation during laparoscopic hepatectomy. Its applications have expanded from tumor localization to segmental staining, delineation of anatomical resection planes, margin assessment, biliary visualization, and evaluation of parenchymal perfusion. Current evidence indicates that ICG-guided surgery is associated with improved detection of small or superficial lesions, higher R0 resection rates, and improveme …

28.08.2026journal-article

Frontiers in Artificial Intelligence

An optimized block-based intuitionistic fuzzy framework for multi-focus image fusion

Ragavendirane M.S, J. Reegan Jebadass, S. Dhanasekar, S. Lakshmanan

Introduction Multi-focus image fusion aims to generate a single all-in-focus image by combining multiple images captured at different focal depths. However, accurately identifying focused and blurred regions remains challenging due to real-world focus transitions and the uncertainties inherent between sharp and defocused areas. Methods To address these limitations, this article presents a new multi-focus image fusion method employing a novel intuitionistic fuzzy generator. In the proposed framework, an input image …

28.08.2026journal-article

Bolu Abant Izzet Baysal Universitesi Tip Fakultesi Abant Tip Dergisi

Guideline Concordance of Large Language Models in the Management of Ureteral Stones: A Clinical Vignette-Based Comparative Study

Engin Denizhan Demirkıran

ObjectiveLarge language models (LLMs) are increasingly used to answer medical questions, but their reliability in guideline-based urological decisions remains uncertain. This study aimed to evaluate the concordance of three widely used LLMs with the European Association of Urology (EAU) 2026 guideline recommendations for the active management of ureteral stones.Materials and MethodsIn this cross-sectional, vignette-based comparative study, the EAU 2026 ureteral-stone treatment algorithm was converted into 40 standa …

28.08.2026journal-article

International Journal of Public Health

The dominance of leisure-time physical activity research: implications for health inequalities

Ragna Stalsberg

Physical activity research has substantially advanced our understanding of health benefits, yet it remains dominated by a narrow focus on leisure-time physical activity. This focus overlooks diverse physical activity practices in other domains and systematically misrepresents the experiences of low socioeconomic status groups. Methodological biases, including participant selection and physical activity assessment tools, further limit representativeness and weaken external validity, which contribute to epistemic inj …

28.08.2026journal-article

ISPRS International Journal of Geo-Information

A Study on the Development and Future Directions of the National Digital Twin: A Case Study of Korea

Byeongsun Kim

The rapid advancement of digital twin technologies has increased the importance of establishing interoperable geospatial information standards for national-scale Digital Twin implementation. The Republic of Korea has developed the National Digital Twin (NDT) standard framework based primarily on OGC CityGML 3.0. This study presents a case-study-based analysis of the development and application of the Korean NDT standards, focusing on how a geospatial standard framework can be structured and extended to support a na …

28.08.2026journal-article

Journal of Clinical Medicine

Lipoprotein(a) in Personalized Cardiovascular Prevention: Risk Stratification, Coronary Artery Calcium, and Emerging Lp(a)-Lowering Therapies

Alveena Batool Syed, Samuel Michalak, Indra Kiran Reddy Potulapati, Aravinthan Vignarajah, Gautam V. Shah

Lipoprotein(a) [Lp(a)] is an independent and causal risk factor for atherosclerotic cardiovascular disease (ASCVD) and calcific aortic valve stenosis (CAVS), with plasma levels largely genetically determined and minimally influenced by lifestyle. Contemporary dyslipidemia guidelines now recommend at least one lifetime measurement and increasingly incorporate Lp(a) into personalized cardiovascular risk evaluation. Recent guideline updates integrate traditional risk estimation with risk-enhancing factors and coronary …

28.08.2026journal-article

Frontiers in Global Women's Health

Evaluation of the relationship between the Desire to Avoid Pregnancy Scale and contraceptive use among women living with HIV in western Kenya

Briend Donanty Kilone, Surya Sruthi Bhamidipalli, Caroline Kerich, Sammy Changwony, John Humphrey, Mercy Maina, Julie Thorne, Shukri A. Hassan, Mehar Maju, Kara Wools-Kaloustian, Beatrice Jakait, Rena C. Patel, Caitlin Bernard

Background Unintended pregnancies place women living with HIV (WLHIV) at risk for maternal and neonatal adverse outcomes. Counseling around pregnancy preferences is important but complex, and there is insufficient evidence around best practices to assess and respond to reproductive health needs. Objective This study aimed to compare responses to the Desire to Avoid Pregnancy (DAP) scale to assess pregnancy preferences, with the dichotomous traditional question “Are you trying to become pregnant within the next one …