Frontiers in Veterinary Science
Clinical observations, environmental parameters, and gut microbiota alterations associated with gas bubble disease in the endangered Anji salamander (Hynobius amjiensis)
Gas bubble disease (GBD) is a non-infectious disease caused by the supersaturation of total dissolved gas (TDG) in aquatic environments, which can damage multiple tissues and organs in aquatic animals and be potentially fatal in severe cases. This study reports, for the first time, clinical symptoms resembling GBD in wild larvae of the endangered Anji salamander ( Hynobius amjiensis ). By combining clinical observations, habitat water quality testing, and 16S rRNA sequencing, we investigated the ecological drivers …