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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
28.08.2026journal-article

Journal of Clinical Medicine

Development of a Multidomain Conceptual Framework for Frozen Shoulder: A Systematic Review Integrating Clinical, Biological, Psychological and Lifestyle-Related Contributors

Santiago Navarro-Ledesma, José Javier Pérez-Montilla, Dina Hamed-Hamed, Fabrizio Brindisino, Filip Struyf

Background/Objectives: Frozen shoulder (FS) is increasingly recognised as a heterogeneous condition in which clinical presentation, metabolic/endocrine burden, imaging phenotype, psychological factors, lifestyle-related contributors, and inflammatory biology may all contribute to disease expression and outcome. However, these contributors have not previously been integrated within a unified multidomain framework for whole-person phenotyping. To develop an evidence-derived multidomain conceptual framework for FS by …

28.08.2026journal-article

Lean Construction Journal

Beyond Data: Conceptualizing Human-Centric Digital Twins for the Future of Construction

Lynn Shehab, Gaang Lee, Farook Hamzeh

Research Question: How can Human-Centric Digital Twins (HCDTs) be conceptually structured and practically implemented in construction projects to integrate physiological, behavioral, cognitive, and environmental data for improving worker safety, well-being, and operational performance? Purpose: To propose a comprehensive HCDT framework for construction and to present a structured implementation roadmap that translates this conceptual framework into a practical and phased deployment strategy. Research Design/Method: …

28.08.2026journal-article

Management Decision

Exploring the influence of generative artificial intelligence on job satisfaction in SMEs: insights from managers

Maria Ijaz Baig, Elaheh Yadegaridehkordi

Purpose This study aims to investigate the impact of “generative artificial intelligence (GenAI)”on managerial job satisfaction in “small and medium-sized manufacturing enterprises (SMEs)”, with a specific focus on work quality and decision-making effectiveness. Design/methodology/approach Grounded in the “unified theory of acceptance and use of technology (UTAUT)” and the “expectation-confirmation model (ECM)”, this study also incorporates additional constructs such as ethical use, perceived GenAI value, and avail …

28.08.2026journal-article

Journal of Public Health in Africa

Admission haemoglobin and albumin as correlates of central nervous system inflammation in rhodesiense human African trypanosomiasis at Rumphi District Hospital, Malawi

Westain T. Nyirenda, Lovemore Mapahla, Bonheur Dounebaine, Nebiyu Dereje, Peter S. Nyasulu

Background: Rhodesiense human African trypanosomiasis (rHAT) is an acute zoonotic infection that can rapidly progress to central nervous system (CNS) disease. As lumbar puncture is no longer routinely required for treatment selection, district hospitals need accessible measures associated with CNS inflammatory burden. Aim: This study aimed to evaluate routine admission clinical and laboratory measures as correlates of cerebrospinal-fluid white-cell count and to describe changes in this count during early hospital c …

28.08.2026journal-article

Hacettepe University Faculty of Health Sciences Journal

Odyologların Demans, Bilişsel Tarama ve Demanslı Hastaya Odyolojik Yaklaşım Hakkındaki Bilgi ve Görüşlerinin İncelenmesi

Merve Deniz Sakarya

Amaç: Çalışmanın amacı odyologların, demans tanısı ya da şüphesi olan yaşlılarla çalışma deneyimlerini incelemek, bilişsel tarama hakkındaki bilgi ve görüşlerini saptamak ve demanstan şüphelenildiği durumlarda uygulamada yaptıkları değişiklikleri ortaya koymaktır.Gereç ve Yöntem: Çalışmaya 23-50 yaş arası, 112’si kadın (%74,2) ve 39’u erkek (%25,8) olmak üzere toplam 151 odyolog/odyoloji ve konuşma bozuklukları uzmanı katılmıştır. Çalışmanın verileri online anket formu ile toplanmıştır. Anket “odyologların demanslı …

28.08.2026journal-article

PLOS One

Prevalence of mental health, mental well-being, and school connectedness in UK secondary school students in 2021/2022: Results from the South West - School Health Research Network pilot study

Patricia N. Albers, Emily Widnall, Lorna Hatch, Georgina Hopkins, Catherine Sharp, Judi Kidger, Frank de Vocht, Eileen Kaner, Esther M. F. van Sluijs, Hannah Fairbrother, Russell Jago, Rona Campbell

Background Young people are experiencing more mental health challenges, and connection to school can improve this. This study aimed to investigate adverse mental health, mental well-being, and school connectedness among secondary school students according to gender, academic year group, and socioeconomic status to identify areas for intervention. Methods Self-report questionnaire data from 5193 Year 8 and 10 students (12−15 years) in the UK South West – School Health Research Network (SW-SHRN) were analysed. Weight …

28.08.2026journal-article

Journal of Health Psychology

Neighborhood effects on Black adolescents’ obesity risk: The mediating role of family experiences

Olivenne D. Skinner, Vanessa V. Volpe, Juan Del Toro, April R. Vollmer, Joanna Adamusik

We examined longitudinal associations between neighborhood environments (walkability, area deprivation, and traffic volume) and obesity risk, tested sex differences, and evaluated family experiences as mediators. Participants were 1325 Black youth (52% male; M age = 9.5) and caregivers from the first 3 years of the Adolescent Brain Cognitive Development (ABCD) Study. We used participants’ survey responses and measures of neighborhood context from publicly available sources. Greater neighborhood walkability predicte …

28.08.2026journal-article

JMIR Medical Informatics

A Conceptual Model for Ambient AI Adoption: Perspectives From Academia and Industry

Joshua Biro, Jesse M Pines, Sudha Jayaraman, Vamsi Chagari, Raj Ratwani

Abstract Ambient AI technologies are increasingly marketed as solutions to reduce clinician burden and improve care efficiency; however, real-world performance varies widely across clinical settings. Health care provider organizations face challenges in determining which aspects of ambient AI performance matter most and how to obtain meaningful information about those aspects from vendors or through internal evaluation. This article presents a shared mental model to guide health system leaders in conceptualizing am …

28.08.2026journal-article

REMUNOM

A APLICAÇÃO DO PENSAMENTO COMPLEXO DE EDGAR MORIN NA MEDICINA E EDUCAÇÃO EM SAÚDE: UMA REVISÃO DE LITERATURA

Renato Faria da Gama, Lilian Coelho Heringer Diniz, Peterson Gonçalves Teixeira, Rodolfo Moura Pereira, Crisóstomo Lima do Nascimento

O modelo biomédico cartesiano, consolidado pelo Relatório Flexner no início do século XX, impôs uma trajetória de hiperespecialização e fragmentação do conhecimento na medicina. Embora tenha propiciado inegáveis avanços tecnológicos, essa abordagem reducionista limitou a capacidade dos profissionais de compreender o paciente em sua totalidade existencial e biopsicossocial. O presente artigo de revisão narrativa analisa as contribuições do Pensamento Complexo de Edgar Morin (1921–2026) como alternativa epistemológic …

28.08.2026journal-article

Russian Journal of Clinical Dermatology and Venereology

Optimization of systemic isotretinoin dosing in patients with acne at high risk of recurrence

I.M. Khismatulina

Objective. To develop a model for predicting the likelihood of acne recurrence and to compare the efficacy and safety of systemic isotretinoin therapy at doses of 0.5 and 1 mg/kg body mass in patients with a high risk of recurrence. Materials and methods. At the first stage, a predictive model was constructed using logistic regression based on an analysis of clinical, anamnestic, laboratory, and instrumental data from 511 patients. At the second stage, 72 patients with moderate to severe acne and a high risk of rec …

28.08.2026journal-article

Arthritis & Rheumatology

Cancer in systemic sclerosis: clinical associations and prognostic impact from the EUSTAR registry

Antonio Tonutti, Francesca Motta, Liala Moschetti, Cosimo Bruni, Carina Mihai, Claudia Iannone, Maria Rosa Pellico, Stefano Stano, Stefano Erba, Claudia Barison, Eleonora Pazzi, Andrea Benini, Beatrice Moccaldi, Kurszán Jász Dávid, Ágnes Ágoston‐Szabó, Beatrice Gabrielli, Francesca Nava, Dóra Tari, Francesca Romana Di Ciommo, Yuri Sasaki, Gonçalo Boleto, Radim Bečvář, Alejandro Brigante, Britta Maurer, Massimiliano Limonta, Rahma A. Elziaty, Fabiola Atzeni, Lilian Maria López Núñez, Roberta Foti, Francesco Benvenuti, Brigitte Granel, Elena Rezus, Leila Caillault, Sophie Blaise, Cristiana Sieiro Santos, Fabio Cacciapaglia, Roberto Giacomelli, Rossella De Angelis, Serena Guiducci, Duygu Temiz Karadag

Background Cancer represents a major cause of mortality in systemic sclerosis (SSc). Established risk factors are limited to specific subsets, particularly early diffuse anti‐RNA polymerase III (POLR3)‐positive disease, needing further exploration. Methods We performed a nested case‐control study within EUSTAR: cases were SSc patients developing cancer at any timepoint; controls were cancer‐free SSc matched for age and disease duration. Malignancies were classified as synchronous to SSc onset (±3 years), subsequent …

28.08.2026journal-article

Oncology Reviews

Clinical value of combined SHOX2 and RASSF1A methylation in lung cancer diagnosis across tissue and liquid biopsy samples: a systematic review and meta-analysis

Ting Wang, Jianguo Zhang, Jiayang Wang, Xiaoqun Dong, Qiushi Lin, Leiming Guo, Bo Zhang, Yue Cao, Yining Zhai, Mathhew Hadfield, Khan Hina, Abbas E. Abbas, Hong Ge, Liang Cheng, Hang Xing, Yifei Liu

Lung cancer remains the leading cause of cancer-related mortality worldwide, with poor prognosis in advanced stage diseases. Although early diagnosis has the potential to improve patient outcomes, current diagnostic methods remain suboptimal, highlighting the need for accurate molecular biomarkers. We systematically reviewed 49 studies to evaluate the diagnostic performance of SHOX2 methylation, RASSF1A methylation, and their combined panel for lung cancer detection. The combined SHOX2/RASSF1A methylation panel dem …

28.08.2026journal-article

Frontiers in Medicine

Case Report: Reversible neurological involvement associated with Chlamydia psittaci infection: clinical, cerebrospinal fluid and neuroimaging features of three fully documented cases

Hao Zhang, Jia Zhou, Yong Chen, Xiuyan Wang, Xiaoping Luo, Guilan Yang, Zhenzhen Gui, Shuni Wang, Yanan Zhang, Juan Chen

Background Chlamydia psittaci infection presents mainly as severe pneumonia, but a subset of patients develop neurological symptoms. Previous reports are largely single cases and frequently lack cerebrospinal fluid (CSF) data, opening pressure and follow-up imaging, which makes the mechanism of neurological involvement difficult to determine. Methods We retrospectively analysed three patients with C. psittaci infection confirmed by metagenomic next-generation sequencing (mNGS), all of whom developed neurological ma …

28.08.2026journal-article

Education Sciences

Can Digital Technologies Promote Physical Activity in Rural Youth? A Systematic Review and Practical Recommendations

Amanda Camacho-Illana, Rosa Gómez-Martínez, Pablo Ramírez-Espejo, Alberto Ruiz-Ariza

This systematic review analysed the role, opportunities and challenges of digital technologies in promoting physical activity among rural children and adolescents aged 10–18. By identifying and analyzing 10 eligible studies across four major databases between June 2016 and June 2026, the research classified the tools used into five categories: behaviour-monitoring technologies (like wearable activity trackers), educational technologies (digital learning platforms), communication and social media technologies, immer …

28.08.2026journal-article

Journal of Clinical Medicine

Association Between the Number of Metabolic Syndrome Components and Markers of Subclinical Vascular Damage: A Retrospective Cross-Sectional Study

Monika Starzak, Grzegorz K. Jakubiak, Natalia Pawlas, Grzegorz Cieślar, Agata Stanek

Background: Metabolic syndrome (MetS) refers to the coexistence of cardiometabolic disorders, such as hyperglycemia, elevated blood pressure, visceral obesity, or features of atherogenic dyslipidemia. A diagnosis of MetS significantly increases the risk of cardiovascular disease (CVD). However, the exact relationship between the number of MetS components, regardless of their constellation, and features of subclinical cardiovascular dysfunction remains unclear. This study aimed to explore the relationship between th …

28.08.2026journal-article

Education in Medicine Journal

Evaluating the Perceived Quality of Educational Services Among Clinical Pathology Residents in Hasanuddin University Using the SERVQUAL Instrument

Kartika Paramita, Andi Alfian Zainuddin, Berti Nelwan, Budu, Irfan Idris, Agussalim Bukhari

The SERVQUAL instrument is widely used to assess service quality across various sectors; however, its application in specialist medical education remains limited. This study evaluated the educational service quality of the Clinical Pathology Specialist Programme at Hasanuddin University, Indonesia, from the residents’ perspective using the SERVQUAL model. Out of 84 residents, 64 completed thestandardised questionnaire measuring five service dimensions: reliability, assurance, tangibles, responsiveness, and empathy. …

28.08.2026journal-article

Clinical and Experimental Dermatology

Effectiveness, safety and tolerability of Ozenoxacin 2% lotion vs Clindamycin 1% lotion in mild to moderate truncal acne: An open label randomized controlled clinical trial

Anupam Das, Sambit Chatterjee, Saikat Banerjee, Sujata Sengupta

Abstract Background Truncal acne is a frequently encountered but relatively understudied manifestation of acne vulgaris and is often associated with significant physical discomfort and psychosocial impact. Topical clindamycin has been extensively used in mild to moderate acne, however, there are concerns regarding antimicrobial resistance which has prompted interest in alternative topical agents. Ozenoxacin, a non-fluorinated quinolone, offers broad-spectrum antibacterial activity with minimal systemic absorption. …

28.08.2026journal-article

Discover Artificial Intelligence

A responsible artificial intelligence framework for translational readiness of machine learning biomarker models in clinical decision support

Vahid Habibzadehomran

Abstract Machine learning (ML) has expanded biomarker modelling across molecular, imaging, laboratory, electronic health record, and multimodal data, yet strong retrospective performance does not by itself establish clinical readiness. This structured narrative review examines the evidence required to translate ML-based biomarker models into clinical decision-support systems. PubMed, Scopus, Web of Science, and Google Scholar were searched for peer-reviewed literature addressing biomarker validation, external valid …

28.08.2026journal-article

Journal of Prevention

Temporal Data Structure Is Not Causal Identification: A Practical Framework for Appraising Causal Claims in Prevention and Population Health Research

Sunday Azagba, Galappaththige S. R. de Silva

Abstract Temporal data structure is not an identification strategy. In manuscript review and reporting, cross-sectional and longitudinal labels are sometimes used as shorthand for judging whether causal claims are appropriate. Whether a causal claim is credible depends on the effect being considered, what makes the comparison informative, what assumptions are required, and whether the analysis and supporting evidence address the main threats. We define temporal data structure as the temporal and sampling organizati …

28.08.2026journal-article

Interactive Journal of Medical Research

How Many Instruments Do We Need? Strengths, Weaknesses, and Potentials for Further Developments of Digital Health Literacy Measurement Instruments: Narrative Overview of Reviews and Content Analysis

Pauline Kaboth, Lorenz Harst, Jochen Schmitt, Madlen Scheibe

Abstract Background With the ongoing digitalization of health care, digital health literacy (DHL) is becoming increasingly important, requiring appropriate measurement instruments (DHLMIs). However, the wide range of available DHLMIs makes selection difficult and raises questions about their suitability and comparability. Objective This review aimed to provide an overview of available DHLMIs for adult populations and to compare their dimensions, identifying overlaps and differences to determine which (key) dimensio …

28.08.2026journal-article

Measurement Science and Technology

Deep learning-based approach to mitigating reference pattern loss in Digital Image Correlation

Kim HyunSoo, Hyeon-Gyu Min, Dong-Joong Kang, Jun-Hyub Park

Abstract In this study, a deep learning-based Digital Image Correlation (Deep DIC) method is applied to mitigate some limitations of conventional DIC techniques. Traditional DIC suffers from a significant reduction in displacement measurement accuracy when the reference pattern within the region of interest is partially or completely lost due to deformation. The proposed method addresses this issue by enabling robust displacement estimation even when the reference pattern becomes partially degraded or moves outside …

28.08.2026journal-article

Public Health Journal

Penicillin G Acylase sebagai Biokatalis Dalam Sintesis Enzimatis Antibiotik Beta-Laktam

Wiwin Try Ayu Rombe, Iin Hardiyati, Susi Kusumaningrum, Ahmad Wibisana, Errol Rakhmad Noordam, Salma Hilmy Rusydi Hashim

Antibiotik $\beta$-laktam banyak digunakan dalam terapi infeksi bakteri, namun produksi kimiawinya menghasilkan limbah tinggi dan menggunakan bahan berbahaya. Penicillin G acylase (PGA) menjadi biokatalis kunci untuk hidrolisis penisilin G menjadi asam 6-aminopenisilanat (6-APA) serta sintesis antibiotik semisintetik seperti ampisilin dan amoksisilin. Kajian literatur ilmiah 2015–2025 ini bertujuan menganalisis karakteristik, mekanisme katalitik, dan strategi peningkatan kinerja PGA dalam sintesis enzimatis antibio …

28.08.2026journal-article

Frontiers in Immunology

Clinical characteristics and differential diagnosis model of IgAV with gastrointestinal symptoms and acute abdominal disease: an observational controlled study

Yu Zhang, Yang Liu, Zhiling Li, Wenzhong Niu, Zhixin Zheng, Yuhan Gu

Background Gastrointestinal symptoms of IgA vasculitis (IgAV) patients are relatively common. These symptoms are similar to those of acute abdomen, coupled with the poor expressive ability of young children and children, which leads to the possibility of misdiagnosis and delayed diagnosis. Methods This is a retrospective observational controlled study. All the patients were treated in Nanyang Central Hospital. The demographic, medical history and laboratory tests data were collected from medical records. The charac …

28.08.2026journal-article

Neurological Research and Practice

Clinical outcomes and unmet therapeutic needs in new-onset refractory status epilepticus: evidence from a retrospective cohort

Clara Jünemann, Meike Menche, Marc Philipp Bergmann, Sascha Strehlau, Panagiota-Eleni Tsalouchidou, Joane Winkel, Ole J. Simon, Lena Habermehl, Katja Menzler, Patrick Schramm, Lars Timmermann, Susanne Knake, Leona Möller

Abstract Background New-onset refractory status epilepticus (NORSE) is a rare, life-threatening condition occurring in individuals without prior epilepsy or acute structural, toxic, or metabolic causes. Its etiology often remains cryptogenic, and inconsistent terminology hampers early recognition and treatment. This study aims to better characterize NORSE to support faster clinical diagnosis and management. Methods We retrospectively identified all adult patients with status epilepticus (SE) admitted to the Departm …