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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
28.08.2026journal-article

Medicina

Clinical and Dermoscopic Determinants of Surgical Decision-Making in Skin Cancer Screening: A Retrospective Analysis

Adrian Chwojnicki, Sebastian Makuch, Hanna Adamska, Michalina Świetlicka, Maja Hrynczyszyn, Inga Buława, Paulina Piesch, Jacek Polański, Wojciech Tański

Background and Objectives: Deciding which pigmented or non-pigmented skin lesions require surgical excision, as opposed to continued observation, is a common challenge in everyday dermatologic practice. Although dermoscopy is well established as a tool that improves melanoma detection accuracy compared with naked-eye examination, real-world evidence on how demographic profile, patient history, and dermoscopic impression jointly influence the surgical decision remains limited. This study examined the clinical and de …

28.08.2026journal-article

Journal of Contemporary Decision Science

An Interval-Valued Fermatean Fuzzy SWOT-AHP-Based Model for Assessing Artificial Intelligence Adoption for Sustainable Development Goal 4

Mouhamed Bayane Bouraima

This study adopted an interval-valued Fermatean fuzzy analytical hierarchy process (IVFF-AHP)-based strategic approach to assess the strengths, weaknesses, opportunities, and threats (SWOT) related to the role of artificial intelligence (AI) in achieving quality education under Sustainable Development Goal 4 (SDG 4). First, 14 SWOT factors were identified based on a literature review. Data were then collected from three domain experts, and the IVFF-AHP approach was applied to determine the weights of the SWOT facto …

28.08.2026journal-article

Pharmaceutics

Food Effects, Pharmacokinetic Drug–Drug Interactions, and Clinical Optimization of Oral Anticancer Agents

Abdullah A. Assiri

Oral targeted therapies now constitute a substantial and growing proportion of anticancer drug therapy, shifting administration from the controlled intravenous setting to patient-managed oral therapy in the outpatient setting, where systemic exposure depends on factors that parenteral therapy largely bypasses. Food effects, gastric pH, first-pass metabolism, transporter activity, organ function, concomitant medications and adherence contribute to variability in exposure, and many oral anticancer agents have narrow …

28.08.2026journal-article

Nutrients

Plant Protein-Derived Bioactive Peptides: From Mechanistic Promise to Health-Promoting Functional Foods

Maria Czernicka, Patrycja Sowa-Borowiec, Anna Wondołowska-Grabowska

Plant protein-derived bioactive peptides have attracted increasing interest as potential ingredients for health-promoting functional foods because of their reported cardiometabolic, antioxidant, anti-inflammatory, immunomodulatory, antimicrobial, gastrointestinal, and satiety-related activities. However, the field remains dominated by peptide discovery, in silico prediction, enzyme-inhibition assays, simulated digestion, and preclinical models, whereas successful translation into clinically supported and technologi …

28.08.2026journal-article

Academic Visions

Project-Analytical Learning as a Pedagogical Condition for Developing the Digital Competence of Future Masters in Economics

Volodymyr Volodymyrovych Andrusiv

The purpose of the study is to theoretically substantiate project-analytical learning as a pedagogical condition for developing the digital competence of future masters in economics and to design a structural and content model for its implementation in the educational process. The object of the study is the professional training of future masters in economics at higher education institutions. The subject covers the content, organisational mechanisms, methods and tools of project-analytical learning aimed at develop …

28.08.2026journal-article

Journal of Clinical Medicine

Development of a Multidomain Conceptual Framework for Frozen Shoulder: A Systematic Review Integrating Clinical, Biological, Psychological and Lifestyle-Related Contributors

Santiago Navarro-Ledesma, José Javier Pérez-Montilla, Dina Hamed-Hamed, Fabrizio Brindisino, Filip Struyf

Background/Objectives: Frozen shoulder (FS) is increasingly recognised as a heterogeneous condition in which clinical presentation, metabolic/endocrine burden, imaging phenotype, psychological factors, lifestyle-related contributors, and inflammatory biology may all contribute to disease expression and outcome. However, these contributors have not previously been integrated within a unified multidomain framework for whole-person phenotyping. To develop an evidence-derived multidomain conceptual framework for FS by …

28.08.2026journal-article

Medicine

Comparison of artificial intelligence-assisted or CT-based 3-dimensional preoperative planning with conventional 2-dimensional templating in total hip arthroplasty

Liyan Yang, Mingxing Tang, Wenjie Chen, Li Yang

Background: Implant planning is essential for prosthesis matching in total hip arthroplasty (THA). Conventional 2-dimensional (2D) templating has limitations in predicting implant size. Recently, artificial intelligence (AI)-assisted 3-dimensional (3D) planning and computed tomography (CT)-based 3D planning have been increasingly applied clinically. However, 3D planning methods remain heterogeneous, making the evidence difficult to interpret. This study aimed to systematically evaluate AI-assisted or CT-based 3D pr …

28.08.2026journal-article

Clinical EEG and Neuroscience

Early Frontal qEEG Markers Predict Delayed Cognitive Recovery After Mild-to-Moderate Ischemic Stroke: A Prospective Cohort Study

Vy Tuong Nguyen, Trang Ho Thu Quach, Hiep Do, Kien Trung Duong, Khoa Nhat Bui, An Gia Pham, Huong Ha, Thang Cong Tran

Background and Objective Post-stroke cognitive impairment affects 30%–60% of survivors, yet predicting which patients will demonstrate delayed recovery remains challenging. We investigated whether early quantitative electroencephalography (qEEG) markers can identify patients with cognitive recovery potential during the critical 3–6 month post-stroke period. Methods This prospective cohort study enrolled patients with first-time supratentorial ischemic stroke (NIHSS <15). Resting-state EEG was recorded at 8 ± 1 days …

28.08.2026journal-article

Interdisciplinary Social Studies

Implementation of A Web-Based Multi-Role Business Intelligence Dashboard for Retail Sales Monitoring at Astra Honda Cooperative

Arya Dimas Cakraningrat, Yustika Erliani

The rapid advancement of information technology has encouraged organizations to utilize data as a strategic asset to support business operations and decision-making. Retail sales management in cooperative organizations often faces challenges in monitoring sales performance due to fragmented data sources and limited access to timely information. This study aims to implement a web-based multi-role Business Intelligence dashboard for retail sales monitoring at Astra Honda Cooperative. The system was developed using th …

28.08.2026journal-article

American Journal of Health Promotion

The Impact of Prenatal Dental Care Education on Oral Health Knowledge and Practices Among Pregnant Women in Cuiabá, Mato Grosso, Brazil

João Guilherme Medeiros, Aurélio Rosa da Silva Júnior, Victoria Giovana Campos, Lorena Souza Castro Altoé, Matheus Correia Casotti, Elizeu Fagundes de Carvalho, Raman Bedi, Iúri Drumond Louro, Débora Dummer Meira, Sonia Groisman

Purpose To evaluate the effect of an educational intervention based on the Oral Health and Your Pregnancy booklet on the knowledge, attitudes, and behaviors of pregnant women in primary care in Cuiabá, Brazil. Design Quantitative pre-post intervention study without a control group. Setting A primary healthcare unit in Cuiabá, Mato Grosso, Brazil. Sample 374 pregnant women in the first to third trimester. Intervention A 30-minute lecture and practical demonstration of oral hygiene. Measures Sociodemographic question …

28.08.2026journal-article

Journal of Health Psychology

Lived experiences, adherence, and transformation in patients with treatment-resistant depression undergoing transcranial magnetic stimulation (TMS): An interpretative phenomenological study

Margit Julia Guerra Ayala, Marcelo Pablo Aramayo Zamalloa, María del Rosario Ccahuana Ranilla, Lucero Isabel Vílchez Herencia, Miguel David Sánchez Fernández

Treatment-resistant depression (TRD) poses a critical challenge, particularly where conventional treatments fail. Transcranial magnetic stimulation (TMS) has shown clinical efficacy, yet little is known about how patients in Peruvian contexts perceive this intervention. This study explored patients’ lived experiences of TMS, emphasising how adherence, acceptance, and perceived efficacy were shaped by subjective, relational, and contextual factors. Using Interpretative Phenomenological Analysis (IPA), five women age …

28.08.2026journal-article

International Journal of Interactive Multimedia and Artificial Intelligence

Water Distribution System Leakage Detection andLocalization Using Water Demand Automated MeterReading: An Underexplored and Advantageous Technique

Matheus Pilotto Figueiredo, Lizandro de Souza Oliveira, Giancarlo Lucca, Adenauer Correa Yamin, Tiago Da Rosa Lopes

Leakage Detection and Localization (LDL) is one of the greatest challenges to achieving sustainable management in Water Distribution Systems (WDS). As an essential element for the evaluation of LDL approaches, we recently developed LeakG3PD, a simulated dataset that represents WDS behavior in various leakage scenarios, providing all variables and network structure data. Unlike most works in the literature, this article explores the feasibility and advantages of using water demand Automated Meter Reading (AMR) devic …

28.08.2026journal-article

Journal of Public Health in Africa

Admission haemoglobin and albumin as correlates of central nervous system inflammation in rhodesiense human African trypanosomiasis at Rumphi District Hospital, Malawi

Westain T. Nyirenda, Lovemore Mapahla, Bonheur Dounebaine, Nebiyu Dereje, Peter S. Nyasulu

Background: Rhodesiense human African trypanosomiasis (rHAT) is an acute zoonotic infection that can rapidly progress to central nervous system (CNS) disease. As lumbar puncture is no longer routinely required for treatment selection, district hospitals need accessible measures associated with CNS inflammatory burden. Aim: This study aimed to evaluate routine admission clinical and laboratory measures as correlates of cerebrospinal-fluid white-cell count and to describe changes in this count during early hospital c …

28.08.2026journal-article

Lean Construction Journal

Beyond Data: Conceptualizing Human-Centric Digital Twins for the Future of Construction

Lynn Shehab, Gaang Lee, Farook Hamzeh

Research Question: How can Human-Centric Digital Twins (HCDTs) be conceptually structured and practically implemented in construction projects to integrate physiological, behavioral, cognitive, and environmental data for improving worker safety, well-being, and operational performance? Purpose: To propose a comprehensive HCDT framework for construction and to present a structured implementation roadmap that translates this conceptual framework into a practical and phased deployment strategy. Research Design/Method: …

28.08.2026journal-article

Management Decision

Exploring the influence of generative artificial intelligence on job satisfaction in SMEs: insights from managers

Maria Ijaz Baig, Elaheh Yadegaridehkordi

Purpose This study aims to investigate the impact of “generative artificial intelligence (GenAI)”on managerial job satisfaction in “small and medium-sized manufacturing enterprises (SMEs)”, with a specific focus on work quality and decision-making effectiveness. Design/methodology/approach Grounded in the “unified theory of acceptance and use of technology (UTAUT)” and the “expectation-confirmation model (ECM)”, this study also incorporates additional constructs such as ethical use, perceived GenAI value, and avail …

28.08.2026journal-article

Discover Artificial Intelligence

A responsible artificial intelligence framework for translational readiness of machine learning biomarker models in clinical decision support

Vahid Habibzadehomran

Abstract Machine learning (ML) has expanded biomarker modelling across molecular, imaging, laboratory, electronic health record, and multimodal data, yet strong retrospective performance does not by itself establish clinical readiness. This structured narrative review examines the evidence required to translate ML-based biomarker models into clinical decision-support systems. PubMed, Scopus, Web of Science, and Google Scholar were searched for peer-reviewed literature addressing biomarker validation, external valid …

28.08.2026journal-article

Clinical Cancer Research

Weight Loss Responses to Pharmacotherapy in Breast Cancer Survivors: Results from the Adaptive Nutrition and Exercise Weight Loss (A-NEW) Study

Jennifer Y. Sheng, Marianna L. Zahurak, Faith Too, Amanda Montanari, Jennifer Trost, Mengyang Lu, Young Lee, Sheetal Parida, Amanda L. Blackford, Dipali Sharma, Marci Laudenslager, Claire Snyder, Janelle W. Coughlin, Vered Stearns

Abstract Purpose: Behavioral weight loss (BWL) interventions consisting of remote coaching and self-monitoring have limited effectiveness in breast cancer survivors. We conducted a single-arm phase II study evaluating the addition of Contrave for &lt;5% weight loss (%WL) after 2 months of BWL. Patients and Methods: Women with prior stage 0 to III breast cancer and a body mass index ≥27 kg/m2 were eligible and initiated BWL. We collected weight, patient-reported outcomes, and labs at baseline, 2 months, and 6 months …

28.08.2026journal-article

Neurological Research and Practice

Clinical outcomes and unmet therapeutic needs in new-onset refractory status epilepticus: evidence from a retrospective cohort

Clara Jünemann, Meike Menche, Marc Philipp Bergmann, Sascha Strehlau, Panagiota-Eleni Tsalouchidou, Joane Winkel, Ole J. Simon, Lena Habermehl, Katja Menzler, Patrick Schramm, Lars Timmermann, Susanne Knake, Leona Möller

Abstract Background New-onset refractory status epilepticus (NORSE) is a rare, life-threatening condition occurring in individuals without prior epilepsy or acute structural, toxic, or metabolic causes. Its etiology often remains cryptogenic, and inconsistent terminology hampers early recognition and treatment. This study aims to better characterize NORSE to support faster clinical diagnosis and management. Methods We retrospectively identified all adult patients with status epilepticus (SE) admitted to the Departm …

28.08.2026journal-article

Journal of Prevention

Temporal Data Structure Is Not Causal Identification: A Practical Framework for Appraising Causal Claims in Prevention and Population Health Research

Sunday Azagba, Galappaththige S. R. de Silva

Abstract Temporal data structure is not an identification strategy. In manuscript review and reporting, cross-sectional and longitudinal labels are sometimes used as shorthand for judging whether causal claims are appropriate. Whether a causal claim is credible depends on the effect being considered, what makes the comparison informative, what assumptions are required, and whether the analysis and supporting evidence address the main threats. We define temporal data structure as the temporal and sampling organizati …

28.08.2026journal-article

Frontiers in Immunology

Clinical characteristics and differential diagnosis model of IgAV with gastrointestinal symptoms and acute abdominal disease: an observational controlled study

Yu Zhang, Yang Liu, Zhiling Li, Wenzhong Niu, Zhixin Zheng, Yuhan Gu

Background Gastrointestinal symptoms of IgA vasculitis (IgAV) patients are relatively common. These symptoms are similar to those of acute abdomen, coupled with the poor expressive ability of young children and children, which leads to the possibility of misdiagnosis and delayed diagnosis. Methods This is a retrospective observational controlled study. All the patients were treated in Nanyang Central Hospital. The demographic, medical history and laboratory tests data were collected from medical records. The charac …

28.08.2026journal-article

Oncology Reviews

Clinical value of combined SHOX2 and RASSF1A methylation in lung cancer diagnosis across tissue and liquid biopsy samples: a systematic review and meta-analysis

Ting Wang, Jianguo Zhang, Jiayang Wang, Xiaoqun Dong, Qiushi Lin, Leiming Guo, Bo Zhang, Yue Cao, Yining Zhai, Mathhew Hadfield, Khan Hina, Abbas E. Abbas, Hong Ge, Liang Cheng, Hang Xing, Yifei Liu

Lung cancer remains the leading cause of cancer-related mortality worldwide, with poor prognosis in advanced stage diseases. Although early diagnosis has the potential to improve patient outcomes, current diagnostic methods remain suboptimal, highlighting the need for accurate molecular biomarkers. We systematically reviewed 49 studies to evaluate the diagnostic performance of SHOX2 methylation, RASSF1A methylation, and their combined panel for lung cancer detection. The combined SHOX2/RASSF1A methylation panel dem …

28.08.2026journal-article

Frontiers in Medicine

Case Report: Reversible neurological involvement associated with Chlamydia psittaci infection: clinical, cerebrospinal fluid and neuroimaging features of three fully documented cases

Hao Zhang, Jia Zhou, Yong Chen, Xiuyan Wang, Xiaoping Luo, Guilan Yang, Zhenzhen Gui, Shuni Wang, Yanan Zhang, Juan Chen

Background Chlamydia psittaci infection presents mainly as severe pneumonia, but a subset of patients develop neurological symptoms. Previous reports are largely single cases and frequently lack cerebrospinal fluid (CSF) data, opening pressure and follow-up imaging, which makes the mechanism of neurological involvement difficult to determine. Methods We retrospectively analysed three patients with C. psittaci infection confirmed by metagenomic next-generation sequencing (mNGS), all of whom developed neurological ma …

28.08.2026journal-article

Education Sciences

Can Digital Technologies Promote Physical Activity in Rural Youth? A Systematic Review and Practical Recommendations

Amanda Camacho-Illana, Rosa Gómez-Martínez, Pablo Ramírez-Espejo, Alberto Ruiz-Ariza

This systematic review analysed the role, opportunities and challenges of digital technologies in promoting physical activity among rural children and adolescents aged 10–18. By identifying and analyzing 10 eligible studies across four major databases between June 2016 and June 2026, the research classified the tools used into five categories: behaviour-monitoring technologies (like wearable activity trackers), educational technologies (digital learning platforms), communication and social media technologies, immer …