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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
31.08.2026journal-article

Archiv Euromedica

BIOLOGIC THERAPIES IN THYROID EYE DISEASE: FROM IMMUNOPATHOGENESIS TO CLINICAL PRACTICE

Filip Chodań, Krystian Domeracki, Dagmara Laufer, Olga Klimczak, Estera Sośniecka, Adam Miler

Background Thyroid Eye Disease is a complex autoimmune inflammatory disorder associated with Graves’ disease that may lead to orbital tissue remodeling, proptosis, diplopia and vision impairment. Although intravenous glucocorticoids remain the standard first-line therapy for active moderate-to-severe disease, their limited efficacy and adverse effects have stimulated the development of targeted biologic therapies. Aim This narrative review aims to summarize and critically evaluate current and emerging biologic ther …

31.08.2026journal-article

Journal of Korean Dental Association

Oral health status of elderly residents in long-term care facilities and oral care experiences and educational needs of caregivers: A mixed methods study

Min-Joo Shin, Jae-Hun Koh, Eun-Jae Choi, Hye-Jin Kwon, Seon-Jip Kim, Hyo-Jin Lee, Hyewon Suh, Jijun Lim, Jung-Ah Lee, Hyun-Jae Cho

Purpose: This mixed-methods study aimed to investigate the oral health status of elderly residents in long-term care facilities and to explore caregivers' experiences and educational needs regarding oral care.Materials and Methods: Quantitative data were collected from 132 elderly residents in four facilities in Seoul through oral examinations and surveys. Differences in oral health indicators across long-term care grades were analyzed using Kruskal-Wallis and chi-square tests. Qualitative data were gathered throug …

31.08.2026journal-article

Antonie van Leeuwenhoek

Porphyrin and photodynamic therapy as tools against Acinetobacter baumannii

Isabela Dadda dos Reis, Marcelle Oliveira Garcia, Suelen Lopes Lussanrriaga, Kamila Furtado da Cunha, Bernardo Almeida Iglesias, Daniela Fernandes Ramos

Abstract Since the 1990s, Acinetobacter baumannii has become a major global concern owing to its high incidence in hospital-acquired infections. Although antimicrobial resistance is a natural process, it has been enhanced by the widespread use of antimicrobials in human and animal healthcare and is considered a global priority in the development of new drugs. Therefore, antibacterial photodynamic therapy has gained prominence for treating infections caused by multidrug-resistant microorganisms. This involves the us …

31.08.2026journal-article

Frontiers in Public Health

Commentary on structural inequities in global health research funding and practice

Saralees Nadarajah, Samuel Manda, Queensley C. Chukwudum

The testimonies gathered from researchers across Africa present a damning portrait of persistent structural inequities in how international research partnerships are conceived, funded, and executed. These firsthand accounts, spanning multiple countries and decades of experience, reveal patterns of exploitation, marginalization, and systemic bias that undermine both the integrity of scientific inquiry and the dignity of African researchers. What emerges is not merely a collection of isolated grievances but evidence …

31.08.2026journal-article

Scientific Reports

Combined hydrogen and oxygen therapy attenuates vascular cognitive impairment in rats via gut microbiota-derived SCFA-GPR41/PI3K/Akt/Nrf2 signaling

Xinle Fu, Mengzhuo Ma, Yujie Zhang, Yanzhuo Gao, Yuan Li, Jing Luan, Yingying Fan, Yifei Wang, Xiaoya Xue, Ling Ma, Yizhuo Liu, Hao Xu

Abstract Vascular cognitive impairment (VCI), a consequence of chronic cerebral hypoperfusion (CCH), is characterized by neuroinflammation and neuronal apoptosis. Hydrogen-rich and hyperoxygenated solution (HHOS) may attenuate CCH-induced brain injury through antioxidant, anti-inflammatory, and gut microbiota-modulating mechanisms. This study investigated the neuroprotective effects of HHOS via the GPR41/PI3K/Nrf2 pathway, comparing its efficacy to hyperoxygenated solution (HOS) and hydrogen-rich solution (HRS) alo …

31.08.2026journal-article

Financial and credit activity problems of theory and practice

DIGITALIZATION OF PUBLIC-PRIVATE PARTNERSHIP AS A STRATEGIC IMPERATIVE FOR ENSURING THE STATE’S ECONOMIC SECURITY: A BIBLIOMETRIC ANALYSIS AND THE EVOLUTION OF SCIENTIFIC APPROACHES

Larysa Hrytsenko, Ihor Alieksieiev, Oleksandr Hrytsenko, Vitaliy Romanchukevych, Oksana Storozhenko, Iryna Kozhushko

This article is devoted to the timely issues of digitization of public-private partnerships as a strategic tool for ensuring the state's economic security in the context of global instability and war threats. The relevance of the study is determined by the objective need to attract private capital for large-scale post-war economic recovery amidst a critical shortage of budgetary resources. In turn, securing a sufficient level of private investment is only possible through adherence to the principles of transparency …

31.08.2026journal-article

Pregnancy

Pregnancy and glycemic outcomes with hybrid closed‐loop insulin delivery versus sensor‐augmented pump therapy among women with type 1 diabetes

Annabeth Brewton, Radhika Pandit, Jiqiang Wu, Natasha Santhanam, Ellena Privitera, Shaylyn Vickers, Steven Gabbe, William A. Grobman, Mark B. Landon, Christine P. Field, Elizabeth O. Buschur, Kartik K. Venkatesh

Abstract Objective Pregnant women with type 1 diabetes (T1D) increasingly utilize hybrid closed‐loop (HCL) pumps, but pregnancy‐specific algorithms in many countries including the United States are not available. We compared pregnancy and glycemic outcomes between those intending to use off‐label automated HCL versus manual sensor‐augmented pump therapy (SAPT). Methods We conducted a single‐center retrospective study from 2022 to 2025. The exposure was intent to use HCL using non‐pregnancy algorithms versus SAPT (r …

31.08.2026journal-article

Journal of Clinical Medicine

Arterial Wall Compliance of the Lower Limb Arteries in Healthy Adults—A Systematic Review and Meta-Analysis

Cathryn Bassett, Bernhard Hruschka, Saurav Ranjan Mohapatra, Jelle Frankort, Pauline Riedl, Eva Kalkum, Christian Uhl, Alexander Gombert, Panagiotis Doukas

Background/Objectives: Arterial wall compliance is a key biomechanical property influencing local hemodynamics, vascular remodeling, and surgical performance. Despite its clinical relevance, reference values in lower limb arteries remain insufficiently characterized. This systematic review and meta-analysis aimed to synthesize existing evidence on cross-sectional compliance (CC) of the common femoral artery (CFA), superficial femoral artery (SFA), and popliteal artery (PA) in healthy adults. Methods: A systematic l …

31.08.2026journal-article

Journal of Public Health for Tropical and Coastal Region

High Prevalence of Hypercholesterolemia and Central Obesity among Medical Faculty Staff: A Cross-Sectional Study at Universitas Sebelas Maret

Victoria Husadani Permata Sari, Danang Wahansa Sugiarto, Arsita Eka Prasetyawati, Lukman Aryoseto

Introduction: Hypercholesterolemia and central obesity are major modifiable risk factors for cardiovascular disease. Underdiagnosis and low awareness persist regarding these conditions, even among populations with presumed high health literacy, such as staff at medical education institutions. This study aimed to determine the prevalence of hypercholesterolemia and central obesity in staff at the Faculty of Medicine, Universitas Sebelas Maret (FK UNS), and assess the level of individual awareness regarding these con …

31.08.2026journal-article

Diabetic Medicine

The role of sex and ethnicity in the variability of estimated glomerular filtration rate ( eGFR ) in people with type 1 diabetes

Salma Ayis, Murat Ozdede, Luigi Gnudi, Thamer Alobaid, Panagiotis Pavlou, Anastasios Mangelis, Nikolaos Fountoulakis, Aicha Goubar, Janaka Karalliedde

Abstract Aims To examine sex‐based differences in estimated glomerular filtration rate (eGFR) trajectories for people with type 1 diabetes (T1D) over 10 years and to test the hypothesis that sex and ethnicity interaction predicts eGFR decline. Methods A cohort of 1495 individuals, 48% men (81% White, 12% African‐Caribbean and 7% Other) and baseline eGFR ≥45 mL/min/1.73 m 2 was analysed. Group‐based trajectory modelling (GBTM) was used to identify eGFR sex‐specific trajectories, and linear mixed models were used to …

31.08.2026journal-article

Basic & Clinical Pharmacology & Toxicology

Hypotonicity‐Induced WNK1 Phosphorylation Prevents H 2 O 2 ‐Induced Apoptosis in Vascular Smooth Muscle Cells

Yajuan Zhang, Wei Lin, Fengting Lu, Zhujun Liang, Chengcui Huang, Ma mingming, Liang Sijia, Pang Ruiping, Jiaguo Zhou, Yongyuan Guan, Guozheng Liang, Xiaofei Lv

ABSTRACT Vascular smooth muscle cells (VSMCs) are essential for maintaining arterial wall integrity, with their associated apoptosis critically involved in cardiovascular diseases. Intracellular chloride anion (Cl − ) dysregulation is closely linked to apoptosis. However, the underlying mechanism via chloride‐sensitive kinases remains unclear. Here, we show that hypotonic stimulation activates volume‐regulated chloride channels (VRCCs) and induces the phosphorylation of the chloride‐sensitive kinase WNK1. Activated …

31.08.2026journal-article

Pakistan Journal of Health Sciences

Comparative Efficacy of Microneedling with and without Topical Vitamin D3 in Localized Alopecia areata

Rameen Masood, Faria Asad, Hira Tariq, Uzma Amin, Abrar Ul Haq

Alopecia areata represents a T-cell-mediated autoimmune disorder causing non-scarring hair loss. While microneedling demonstrates therapeutic potential, adjunctive strategies to enhance efficacy remain underexplored. Objectives: To compare the efficacy and safety of microneedling combined with topical vitamin D3 versus microneedling monotherapy in localized alopecia areata. Methods: An open-label randomized controlled trial enrolled 80 participants (April–October 2025) with localized patchy alopecia areata affectin …

31.08.2026journal-article

The Journal of Korean Academic Society of Nursing Education

Effects of nursing students’ attitudes toward artificial intelligence on self-directed learning: Analysis of the mediating effects of digital literacy sub-dimensions

Younghye Go, Jeong Miri

Purpose: This study aimed to identify the mediating effects of digital literacy sub-dimensions on the relationship between nursing students’ attitudes toward artificial intelligence (AI) and self-directed learning.Methods: Two hundred nursing students from three universities participated in the study. Data were collected through an online survey conducted from October to November 2025. Analyses were performed using IBM SPSS version 27.0 and PROCESS macro version 4.2.Results: Digital ethics competency mediated the r …

31.08.2026journal-article

Journal of Women's Health

Women’s Health Tracks for Internal Medicine Residency Programs: Current State and Best Practices

Rebeca Ortiz Worthington, Jennifer Rusiecki, Molly Fisher, Jaya Mehta, Swati Shroff, Mindy Sobota, Sarah Tilstra, Melissa A. McNeil

Background: Women’s health (WH) is recognized as a core competency in internal medicine (IM) residency programs, yet residents report inadequate training and low comfort across WH topics. Some IM residencies have established tracks to meet this need, but no comprehensive review of their implementation and structure exists. We describe the current state and best practices for WH tracks in IM residency programs. Methods: We reviewed current WH tracks within U.S. categorical IM residency programs. Program websites wer …

31.08.2026journal-article

Journal of Psychosexual Health

Environmental Pollution Exposure and Its Impact on Mental and Reproductive Health: A Review

Abhinav Sahay, Arundhati Sharma, Upanshu Mishra, Badshah Alam, Rashmi Shekhar, Umesh Kumar

Objective: Environmental pollution is a growing global public health threat and is not limited to classic cardiopulmonary effects, impeding numerous physiological systems. Evidence of an association between environmental contaminant exposures and poor mental health, neurodevelopmental, reproductive, and pregnancy outcomes is increasing. The current evidence on main pollution sources, such as atmospheric pollution, endocrine-disrupting chemicals, heavy metals, persistent organic pollutants, pesticides, per- and poly …

31.08.2026journal-article

Revista Brasileira em Promoção da Saúde

Saúde Mental e Qualidade de Vida no Contexto das Universidades Promotoras de Saúde no Brasil: Revisão Integrativa

Isabelle Rittes Nass de Souza, Samara Silva dos Santos

Objetivo: Identificar estratégias, práticas e desafios descritos na literatura sobre as ações das universidades pertencentes à Rede Brasileira de Universidades Promotoras de Saúde e à Rede Ibero-americana de Universidades Promotoras da Saúde, com foco na saúde mental e na qualidade de vida de estudantes universitários. Método: Trata-se de uma revisão integrativa da literatura. A busca foi realizada em agosto de 2025 nas bases Google Scholar, SciELO e PubMed, na BDTD/CAPES e em repositórios institucionais, utilizand …

31.08.2026journal-article

Australian Review of Applied Linguistics

Political economy and language education

M. Maksud Ali

Abstract Contemporary political economy has redefined relationships between most nation-states and citizens based on neoliberalism, whereby individuals’ dependency on the state is minimised and self-reliance is emphasised. How such a framing of the relationships relates to language education policy has not received notable attention in developing societies. Using a political economy frame and drawing on Bourdieu’s concept of field and his analytical framework of field analysis, together with Lingard and Rawolle’s t …

31.08.2026journal-article

Transactions of The Royal Society of Tropical Medicine and Hygiene

Entomological surveillance in Caribbean wetlands of Colombia reveals Madariaga virus Lineage III in mosquito populations

Richard Onalbi Hoyos-López, María Claudia Atencia-Pineda, Salim Mattar

Abstract Objectives Madariaga virus (MADV) is an emerging arboviral pathogen in Central and South America, but systematic entomological surveillance data remain limited in Colombia. We investigated MADV circulation in mosquitoes from the Alto Cotocá wetlands, Córdoba department, Colombia. Methods Adult mosquitoes were collected during November-December 2017 and February-March 2018 using CDC light traps, Shannon traps, and manual aspiration. A total of 2984 mosquitoes were processed in 136 pools of 1-20 specimens an …

31.08.2026journal-article

Journal of Applied Toxicology

Saccharin Revisited: Chemistry, Metabolism, Toxicology and Human Health Risk Assessment in the Era of Evidence‐Based Food Safety

Amjad Mahmood Qadir, Azad Mohammed Aziz Ahmed, Musa M. Zorab, Rebaz Anwar Omer

ABSTRACT Saccharin is one of the oldest and most extensively used nonnutritive sweeteners, valued for its intense sweetness, chemical stability and negligible caloric contribution. Since its discovery in 1879, it has been widely incorporated into foods, beverages, pharmaceuticals and personal care products, while its safety has remained the subject of considerable scientific and regulatory debate. Early experimental studies linking saccharin to bladder tumour formation in rodents raised concerns regarding its carci …

31.08.2026journal-article

İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi

Artificial Intelligence Addiction, Technostress, and Work-Life Balance Among Academics: An Employee Health Perspective

Raife Aşık, Nida Efetürk, Fatoş Tozak

Aim: This study aims to examine the relationships between artificial intelligence addiction tendencies, technostress levels, and work-life balance among academics within the framework employee health.Method: This study was designed using a correlational survey model within the framework of quantitative research methods. The population of the study consisted of academics working at universities in Türkiye. Data were collected using a sociodemographic information form, the Artificial Intelligence Addiction Scale, the …

31.08.2026journal-article

İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi

Association of Embryology Education with Infertility Knowledge and Attitudes among Medical and Health Sciences Students

Emrah Zayman, Feyza İnceoğlu

Aim: The aim of this study is to compare infertility-related knowledge and attitudes among students from the Faculty of Medicine (basic and clinical phases) and the Faculty of Health Sciences (midwifery and nursing programs), and to investigate the association between embryology education and students' knowledge and attitudes toward infertility.Method: This cross-sectional study included 228 undergraduate students from the Faculties of Medicine and Health Sciences. The sample size was determined by power analysis a …

31.08.2026journal-article

Journal of Sleep Medicine

Changes in Sleep Quality Before and During the COVID-19 Pandemic: The Role of Psychosocial Vulnerability

Jun-Sang Sunwoo

Objectives: The coronavirus disease 2019 (COVID-19) pandemic significantly disrupted daily life and sleep habits. In this study, we aimed to investigate changes in sleep quality before and during the COVID-19 pandemic using a large prospective cohort and identify factors associated with deterioration in sleep quality.Methods: We analyzed 60,056 participants (age, 41.32±6.64 years; female, 23.5%) who completed the Pittsburgh Sleep Quality Index (PSQI) before and during the COVID-19 pandemic. Poor sleep quality was d …

31.08.2026journal-article

Intercontinental Journal of Internal Medicine

Assessment of nutritional parameters in elderly hemodialysis patients

Muhammed Faruk Aşkın, Yener Koç

Aims: Malnutrition is a common and important condition in hemodialysis patients, associated with increased mortality and morbidity. This study aimed to identify parameters that may be associated with the level of malnutrition in elderly hemodialysis patients and to determine the most reliable parameter for detecting malnutrition in the elderly hemodialysis patient population. Methods: This cross-sectional study included 136 patients aged 65 years and older undergoing hemodialysis at four centers. We evaluated socio …

31.08.2026journal-article

International Journal Of Community Medicine And Public Health

Knowledge, attitude, practices and awareness of cervical cancer among female medical students at Faculty of Indigenous Medicine, University of Colombo: a cross-sectional study

Gunaseelan Savithri Sanjeewani, Mohammed Umar Ziard Noorul Farzana, Hasan Ali Afeefa Masha

Background: Cervical cancer, major health problem particularly in South Asia. While it is preventable via vaccination and screening, even were knowledge and practice gaps, among future health care providers. Study aimed to determine the knowledge, attitude, practice and awareness (KAP) regarding cervical cancer among the female medical students at faculty of indigenous medicine (FIM), University of Colombo (UoC). Methods: A descriptive cross-sectional study was conducted among 100 indigenous medical students at Fac …