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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
28.08.2026journal-article

Frontiers in Medicine

Clinical efficacy of Masquelet technique in the treatment of tibial and fibular bone defects caused by severe gunshot wounds

Qiming Sun, Yingjie Cong, Wei Sun, Xinwei Liu, Baolei Guo, Chunli Zhao, Baoxian Hou, Ye Liu, Dapeng Zhou

Objective To explore the clinical efficacy of the Masquelet technique in the treatment of tibial and fibular bone defects resulting from severe gunshot wounds. Methods A retrospective analysis was conducted on six male patients (mean age, 23 ± 5 years; range, 18 to 33 years) with tibial and fibular bone defects resulting from gunshot wounds, treated with the Masquelet technique between January 2022 and January 2024. In Stage 1, blood transfusions and fluid resuscitation were administered to manage shock. Wound debr …

28.08.2026journal-article

Global Health Cases

Strengthening Tobacco Control through Multi-Stakeholder Engagement: The Uttarakhand Tobacco-Free Coalition (UTFC) for Protecting Youth and Communities

Awadhesh Kumar, Mamta Thappa, Manish Kumar Singh, Prema Taneja, Sonu Goel

Abstract Tobacco use remains a significant public health concern in Uttarakhand, with 26.5% of adults reported to use tobacco (Global Adult Tobacco Survey [GATS] 2016–17). Although national frameworks such as the Cigarettes and Other Tobacco Products Act (COTPA), 2003 and the National Tobacco Control Programme (NTCP) provide a clear policy direction, implementation at the state level continues to face practical challenges. These include difficult terrain, dispersed populations, and high population movement in pilgr …

28.08.2026journal-article

EDUTECH : Jurnal Inovasi Pendidikan Berbantuan Teknologi

STRATEGI GURU DALAM MEMANFAATKAN TEKNOLOGI ARTIFICIAL INTELLIGENCE (AI) PADA PEMBELAJARAN BAHASA INDONESIA DI SD ISLAM WACHID HASYIM

Devi Nurrochmah Aprilia, Mohammad Setyo Wardono, Novaria Lailatul Jannah, Hikmah Luqiyah Kartikasari, Rikke Kurniawati

The use of Artificial Intelligence (AI) in Indonesian language learning at the elementary school level is increasingly developing. However, its success depends not only on the availability of technology but also on teachers’ strategies for integrating AI into pedagogically appropriate learning activities. This study aims to describe teachers’ strategies for utilizing AI technology in Indonesian language learning at SD Islam Wachid Hasyim. The study employed a qualitative approach with a case study design. Data were …

28.08.2026journal-article

Humanities and Social Sciences Communications

Radical populist parties receive greater audience support on social media: a cross-platform monitoring of digital campaigning for the 2024 European Parliament election

Philipp Darius, Wiebke Drews, Andreas Neumeier, Jasmin Riedl

Abstract Social media platforms play an increasingly important role in political campaigning, enabling parties to bypass traditional media and mobilize support directly. While prior research highlights the online prominence of far-right and radical populist actors, most studies are limited to single platforms or national contexts. This study presents a cross-platform analysis of digital campaign communication by 401 parties across all 27 European Union member states during the 2024 European Parliament election. Usi …

28.08.2026journal-article

Frontiers in Immunology

Recognition and management of early complications in CAR-T cell therapy and virus-specific T-lymphocyte therapy: a practical clinical reference

Marek Ussowicz, Ewa Jakubczyk, Tomasz Wróbel, Anna Czyż

Background Cellular immunotherapies—including chimeric antigen receptor T-cell (CAR-T) therapies and adoptive transfer of virus-specific T lymphocytes (VSTs) — have transformed the treatment of refractory hematological malignancies and post-transplant infectious complications. Eight products are currently authorized by the European Medicines Agency, encompassing seven autologous CAR-T products targeting CD19 or BCMA and tabelecleucel (Ebvallo), the first approved allogeneic off-the-shelf EBV-specific T-cell product …

28.08.2026journal-article

Journal of Clinical Immunology

Three Decades of Outcomes in Pediatric Inborn Errors of Immunity in a Middle-Income Setting: Survival by IUIS Class and the Role of HSCT

Chanunchida Watcharaporn, Usanarat Anurathapan, Suradej Hongeng, Samart Pakakasama, Wasu Kamchaisatian, Watcharoot Kanchongkittiphon, Wiparat Manuyakorn

Abstract Inborn errors of immunity (IEI) comprise a heterogeneous group of inherited disorders associated with substantial morbidity and mortality, yet long-term outcome data from middle-income countries remain limited. We conducted a retrospective cohort study of 123 children diagnosed with IEI at a tertiary referral center in Thailand between 1991 and 2022 to characterize clinical features, treatment, and survival. Patients were retrospectively classified according to the 2022 International Union of Immunological …

28.08.2026journal-article

Human Psychopharmacology: Clinical and Experimental

Psychopharmacological Mechanisms of Antidepressant Withdrawal: Insights From Venlafaxine

Elliot McClure

ABSTRACT Antidepressant discontinuation syndrome (ADS) is widely reported yet often minimized by terminology that obscures its status as a withdrawal phenomenon. Roughly one‐third of patients using a monotherapy antidepressant develop withdrawal symptoms after discontinuation, with higher rates among patients taking venlafaxine (VEN) and those treated long‐term. VEN's dual transporter pharmacodynamics, its active metabolite, and its wide interindividual pharmacokinetic variability make it a useful model for how tha …

28.08.2026journal-article

ULAKES JOURNAL OF MEDICINE

E-learning as a Strategy to Qualify Health Professionals on the covid-19 Pandemic

Evelyn de Britto Dutra, François Isnaldo Dias Caldeira, Erica Tatiane Da Silva, Kellen Cristina da Silva Gasque

Abstract: This scoping review aimed to map and analyze the e-learning educational strategies developed worldwide to train and qualify health professionals in response to the COVID-19 pandemic, covering the period from the World Health Organization’s declaration of the pandemic on March 11, 2020, to March 2022, which marked two years since its declaration. A Scope Review, based on the Joanna Briggs Institute method, was conducted to identify educational strategies published from 2020 to March 2022. The databases sea …

28.08.2026journal-article

Medicina

Clinical and Dermoscopic Determinants of Surgical Decision-Making in Skin Cancer Screening: A Retrospective Analysis

Adrian Chwojnicki, Sebastian Makuch, Hanna Adamska, Michalina Świetlicka, Maja Hrynczyszyn, Inga Buława, Paulina Piesch, Jacek Polański, Wojciech Tański

Background and Objectives: Deciding which pigmented or non-pigmented skin lesions require surgical excision, as opposed to continued observation, is a common challenge in everyday dermatologic practice. Although dermoscopy is well established as a tool that improves melanoma detection accuracy compared with naked-eye examination, real-world evidence on how demographic profile, patient history, and dermoscopic impression jointly influence the surgical decision remains limited. This study examined the clinical and de …

28.08.2026journal-article

Odovtos - International Journal of Dental Sciences

Maternal Knowledge and Practices Concerning Infant Oral Health in a Group of Pregnant Women

Martha J. Arias-Mendoza, Emilia M. Ochoa-Acosta, Andrés A. Agudelo-Suárez

To identify factors associated with the knowledge and practices of pregnant women regarding their children’s oral health. A cross-sectional study was conducted with 269 pregnant women attending two healthcare institutions in the Santander-(Colombia). A questionnaire was carried out, consisting of 40 questions (nine sociodemographic, seven on the psychosocial dimension [D], thirteen on knowledge [K], and eleven on practices [P]). Scoring scales were established for all dimensions, based on the Median (Me) and Interq …

28.08.2026journal-article

GESTUS MULTIDISCIPLINAR

PRÁTICAS EDUCATIVAS EM NUTRIÇÃO NAS ESCOLAS: O PAPEL DO NUTRICIONISTA NA PROMOÇÃO DA SAÚDE INFANTOJUVENIL

Bruna Regina de Moura Cerquinho, Edjane da Silva Ferreira, Eloyza Evellyn de Lima Barros, Lívia Elizabeth Dias de Andrade, Micaelly Da Silva Nascimento, Rayane Kelly Soares de Lima, Sandrely Vitória Gonçalves da Silva, Isaias Felipe da Silva

O presente estudo teve como objetivo analisar o papel do nutricionista na implementação da Educação Alimentar e Nutricional (EAN) no ambiente escolar e sua articulação com o Programa Nacional de Alimentação Escolar (PNAE). Trata-se de uma revisão integrativa da literatura, realizada a partir de buscas nas bases SciELO, Google Acadêmico e PubMed. Foram identificadas 30 publicações, das quais 18 foram incluídas após a aplicação dos critérios de elegibilidade. Os estudos selecionados foram analisados por meio de sínte …

28.08.2026journal-article

Pharmaceutics

Food Effects, Pharmacokinetic Drug–Drug Interactions, and Clinical Optimization of Oral Anticancer Agents

Abdullah A. Assiri

Oral targeted therapies now constitute a substantial and growing proportion of anticancer drug therapy, shifting administration from the controlled intravenous setting to patient-managed oral therapy in the outpatient setting, where systemic exposure depends on factors that parenteral therapy largely bypasses. Food effects, gastric pH, first-pass metabolism, transporter activity, organ function, concomitant medications and adherence contribute to variability in exposure, and many oral anticancer agents have narrow …

28.08.2026journal-article

Nutrients

Plant Protein-Derived Bioactive Peptides: From Mechanistic Promise to Health-Promoting Functional Foods

Maria Czernicka, Patrycja Sowa-Borowiec, Anna Wondołowska-Grabowska

Plant protein-derived bioactive peptides have attracted increasing interest as potential ingredients for health-promoting functional foods because of their reported cardiometabolic, antioxidant, anti-inflammatory, immunomodulatory, antimicrobial, gastrointestinal, and satiety-related activities. However, the field remains dominated by peptide discovery, in silico prediction, enzyme-inhibition assays, simulated digestion, and preclinical models, whereas successful translation into clinically supported and technologi …

28.08.2026journal-article

Diagnostics

Stratified Analysis of Patients Within the PSA Gray Zone (4–10 ng/mL) and Its Clinical Application Value: Development of a Predictive Model for Clinically Significant Prostate Cancer Using Quantitative Indicators of PSA, ADC, and Relative T2 Value

Pan Hao, Tong Zhu, Ruiqiang Xin, Xiaoyong Lv

Objective: Patients with prostate-specific antigen (PSA) levels in the 4–10 ng/mL gray zone present a diagnostic challenge, as PSA alone cannot reliably distinguish clinically significant prostate cancer (csPCa) from benign conditions or indolent disease, potentially leading to unnecessary biopsies or missed clinically significant disease. This study aimed to develop a risk prediction model for csPCa in this population using clinical indicators and magnetic resonance imaging (MRI) quantitative data, and to evaluate …

28.08.2026journal-article

Revista Científica SOL21 - Standard Open Literature

<b>ECONOMIA DA ATENÇÃO E TRANSFORMAÇÃO DO COMPORTAMENTO DO CONSUMIDOR NA ERA DOS CONTEÚDOS DIGITAIS DE CURTA DURAÇÃO: UMA ANÁLISE DE ESTADO DA ARTE</b>

Michel Souza Silva

A consolidação de plataformas de vídeos de curta duração, como TikTok, Instagram Reels, YouTube Shorts e Douyin, intensificou a disputa pela atenção e modificou a relação entre entretenimento, publicidade e consumo. Este artigo analisa o estado da arte da literatura sobre economia da atenção e comportamento do consumidor em plataformas digitais entre 2020 e 2026. Adota-se abordagem qualitativa, exploratória e bibliográfica, estruturada como State-of-the-Art Review, com busca realizada na plataforma Consensus. O cor …

28.08.2026journal-article

International Journal of Public Health and Medical Research

Study on the Effect of Scaffold Carriers on Tissue Repair and Rehabilitation in Cellular Environment

Yuwei Jiang

Scaffold carriers are three dimensional porous biomaterial structures that provide structural support, metabolic signalling and an appropriate cellular environment for tissue regeneration. This article covers the effects of scaffold carrier mechanisms on tissue healing and rehabilitation in three key tissue systems: bone and cartilage, skin and soft tissue and neural tissue. This review integrates principles of extracellular matrix (ECM) biomimicry, scaffold material classification frameworks and cell-scaffold mech …

28.08.2026journal-article

Applied Artificial Intelligence Research

A Closed-Loop Digital Twin Framework for Sustainable and Resilient Post-Disaster Urban Recovery: Integrating Environmental Assessment, Risk Prediction, and Adaptive Resource Management

Jinghan Li

Natural disasters, climate change, and rapid urbanization have increased the complexity of post-disaster urban recovery, creating challenges in environmental management, risk mitigation, and resource allocation. Conventional recovery approaches often rely on fragmented information and relatively fixed decisions, limiting their ability to respond to changing environmental and recovery conditions. This study proposes a Digital Twin Framework for Sustainable and Resilient Post-Disaster Urban Recovery (DT-SRUR) that in …

28.08.2026journal-article

The British Journal of Psychiatry

Evaluation of the efficacy of support groups in the metaverse for Ukrainian refugees: randomised clinical trial

Cezar Giosan, Catalina M. Popoviciu, Saltanat Zhamaliyeva, Iuliana Zaborot, George Deac, Albert Skip Rizzo

Background Millions of Ukrainians displaced since 2022 experience high rates of depression, anxiety and distress, with major barriers to in-person mental healthcare. Immersive avatar-based virtual reality environments may offer scalable psychosocial support while preserving key therapeutic elements. Aims To evaluate the efficacy of avatar-based virtual reality support groups versus in-person support groups and a waitlist control among Ukrainian refugees in Romania. Method In this 3-arm randomised controlled trial, …

28.08.2026journal-article

Journal of Contemporary Decision Science

An Interval-Valued Fermatean Fuzzy SWOT-AHP-Based Model for Assessing Artificial Intelligence Adoption for Sustainable Development Goal 4

Mouhamed Bayane Bouraima

This study adopted an interval-valued Fermatean fuzzy analytical hierarchy process (IVFF-AHP)-based strategic approach to assess the strengths, weaknesses, opportunities, and threats (SWOT) related to the role of artificial intelligence (AI) in achieving quality education under Sustainable Development Goal 4 (SDG 4). First, 14 SWOT factors were identified based on a literature review. Data were then collected from three domain experts, and the IVFF-AHP approach was applied to determine the weights of the SWOT facto …

28.08.2026journal-article

International Journal of Interactive Multimedia and Artificial Intelligence

Water Distribution System Leakage Detection andLocalization Using Water Demand Automated MeterReading: An Underexplored and Advantageous Technique

Matheus Pilotto Figueiredo, Lizandro de Souza Oliveira, Giancarlo Lucca, Adenauer Correa Yamin, Tiago Da Rosa Lopes

Leakage Detection and Localization (LDL) is one of the greatest challenges to achieving sustainable management in Water Distribution Systems (WDS). As an essential element for the evaluation of LDL approaches, we recently developed LeakG3PD, a simulated dataset that represents WDS behavior in various leakage scenarios, providing all variables and network structure data. Unlike most works in the literature, this article explores the feasibility and advantages of using water demand Automated Meter Reading (AMR) devic …

28.08.2026journal-article

Measurement Science and Technology

DIC-Gel: a digital image correlation-enhanced neural network-based tactile sensor for multi-parameter contact estimation

Jindian Song, Shuang Mei, Xin He, Weijia Wu, Siyi Cheng

Abstract Vision-based tactile sensors (VBTS), widely adopted in robotic end-effectors for tactile cues to support environmental perception and interaction, have attracted significant attention due to their structural simplicity, high spatial resolution, and robustness. However, state-of-the-art VBTS over-rely on complex optical configurations and cumbersome traditional markers, limiting their miniaturization, integration, and practical deployment. To address these limitations, this work proposes a novel VBTS design …

28.08.2026journal-article

Bolu Abant Izzet Baysal Universitesi Tip Fakultesi Abant Tip Dergisi

Distribution of Pain Phenotypes and Their Associations with Clinical, Psychological, and Quality-of-Life Outcomes in Plantar Fasciitis: A Cross-Sectional Study

Bilal Uysal, Ender Salbaş, Nilay Şahin

Background: Plantar fasciitis is traditionally considered a predominantly nociceptive disorder; however, chronic plantar heel pain may include neuropathic-like and nociplastic features that influence clinical presentation and outcomes. This study aimed to describe the distribution of pain phenotypes in patients with plantar fasciitis and to compare clinical, psychological, functional, and quality-of-life outcomes across phenotypes. Methods: In this prospectively recruited cross-sectional study, 100 adults with clin …

28.08.2026journal-article

European Heart Journal - Quality of Care and Clinical Outcomes

The effect of integrated lifestyle modification on quality of life and cost-effectiveness in atrial fibrillation ablation – results from the POP-AF RCT

Jasper Vermeer, Gijs van Steenbergen, Fabienne Vervaat, Sabine Grimm, Dennis van Veghel, Lukas Dekker

Abstract Objectives To evaluate the impact of an integrated lifestyle intervention on quality of life and cost-effectiveness in patients undergoing catheter ablation for atrial fibrillation (AF), compared with usual care. Methods The POP-AF trial randomized patients for their first AF ablation who had at least one modifiable lifestyle-related risk factor between lifestyle intervention and usual care. Quality of life was assessed throughout the trial using the Atrial Fibrillation Effect on Quality of Life (AFEQT) qu …

28.08.2026journal-article

Frontiers in Medicine

The application of artificial intelligence in systemic lupus erythematosus: a bibliometric analysis of current trends and future directions

Ziyi Liu, Wenqian Yu, Xinxin Meng, Jiaying Yan, Qiang Fu

Background Systemic lupus erythematosus (SLE) poses significant clinical challenges due to its heterogeneity and unpredictable relapses. Artificial intelligence (AI) is driving a paradigm shift in SLE management through molecular subtyping and prognostic modeling. However, a comprehensive quantitative analysis of this rapidly growing field is lacking. This study employs bibliometric and visualization methods to systematically map the development, collaboration patterns, and research frontiers of AI in SLE. Methods …