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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
29.08.2026journal-article

African Journal of Pharmacy and Alternative Medicine

Knowledge and Attitudes Toward Cervical Cancer and Human Papilloma Virus Vaccination in Rafiki Area, Rongai Sub-County, Nakuru County, Kenya: A Cross-sectional Study

Mercy M. MICHIRA, Dinah L. SANGURA, Mercy K. JEPCHIRCHIR, Nahashon G. AKUNGA, Wairimu KARAIHIRA, James O. MEROKA, Jim AMISI

The human papillomavirus (HPV) has been proven to be a primary driver in the development of cervical cancer. Despite increasing awareness efforts, Human Papillomavirus (HPV) vaccine uptake remains low in many low-resource settings. This study assessed knowledge and attitudes towards cervical cancer and human papillomavirus vaccination, and predictors of HPV vaccine uptake among individuals aged 15-49 years in Rafiki area, Rongai sub-county, Nakuru County, Kenya. A cross-sectional survey was conducted with 328 parti …

29.08.2026journal-article

Journal of Robotic Surgery

Impact of robotic platform transition on short term outcomes in colorectal cancer surgeries

Rebeca Hara Nahime, Paulo Roberto Stevanato Filho, Tiago Santoro Bezerra, Tomás Mansur Duarte Miranda Marques, Renata Mayumi Takahashi, Bruna Elisa Catin Kupper, Wilson Toshihiko Nakagawa, Ademar Lopes, Samuel Aguiar

Abstract Robotic colorectal surgery is increasingly complex, expanding from pelvic to multiquadrant procedures. Reports on the impact of institutional robotic platform transition remain limited. This study evaluated the challenges and effects of transitioning from the da Vinci Si (dV Si) to the da Vinci X/Xi (dV X/Xi) platform. A prospective observational cohort with historical comparison describing an institutional experience that included consecutive elective robotic colorectal cancer resections performed in 2023 …

29.08.2026journal-article

BMC Surgery

Preoperative biliary stenting is associated with increased bacterial contamination and postoperative inflammation in pancreatic head resections

Sara Al-Madhi, Aristotelis Perrakis, Sara Acciuffi, Fuad Al-Qahom, Maximilian Dölling, Seong Jeong, Peter Lemmer, Maksym Boruta, Mohammad Othman Alhomsi, Mihailo Andric, Frank Meyer, Roland S. Croner, Mirhasan Rahimli

Abstract Background The role of preoperative biliary drainage (PBD) in patients with resectable pancreatic head cancer remains controversial. Although traditionally used to reduce hyperbilirubinemia, increasing evidence suggests an association with higher postoperative morbidity. This study evaluated the impact of preoperative biliary stenting on microbial contamination, postoperative inflammatory response, and clinical outcomes. Methods This retrospective single-center study included 102 patients with preoperative …

29.08.2026journal-article

Journal of the Pediatric Infectious Diseases Society

Beyond the Grain: Correlating Imaging Findings with Mycetoma Pathogens to Optimize Timely diagnosis and Therapy

Mohammed Fadul, Mustaphaa Bahar, Mohamaed Mustfa, Ahmed Fahal, Amel Omer

Abstract Background Mycetoma is a devastating, progressively destructive neglected tropical disease highly endemic in Sudan, which holds the highest documented global case count (prevalence of 14.5/100,000). Clinically, it presents as a painless subcutaneous mass with sinuses and grain discharge. Frequent delayed presentation leads to high morbidity, disability, and often necessitates amputation. Advanced cases present a diagnostic challenge as their radiological appearance mimics osteosarcoma and other severe bone …

29.08.2026journal-article

Quality of Life Research

Deciding on thresholds for clinical relevance of PROMIS-upper extremity v2.0 in patients with upper extremity injury

Suus G. J. van Bruggen, Lore E. de Vreeze, Charlotte M. Lameijer, Frank W. Bloemers, Caroline B. Terwee

Abstract Purpose In this study we focused on gaining better interpretation of the PROMIS-Upper-Extremity v2.0 (PROMIS-UE v2.0) T-score scale for measuring upper extremity function in patients with upper extremity injuries (UEIs). This is fundamental in order to clearly understand the clinical relevance of these outcomes. The aim of this study was to identify interpretive thresholds for mild, moderate and severe upper extremity function problems for PROMIS-UE v2.0 T-scores, in patients with UEIs, by performing a vig …

29.08.2026journal-article

Egyptian Journal of Radiology and Nuclear Medicine

Apparent diffusion coefficient metrics for adult-type diffuse gliomas classified according to WHO 2021: a systematic review

Dragos Gabriel Margalin, Razvan Stanciulescu, Didina-Catalina Barbalata, Corneliu Toader

Abstract Purpose This study aimed to determine the associations of apparent diffusion coefficient (ADC) values with the molecular and histological subtypes of adult-type diffuse gliomas classified in accordance with the 2021 World Health Organization (WHO) Classification of Tumors of the Central Nervous System, fifth edition (WHO CNS5). Methods PubMed, Scopus, Cochrane and Google Scholar were searched to identify relevant studies up to December 2025. The search and selection strategies followed the relevant items o …

29.08.2026journal-article

npj Genomic Medicine

aiDIVA – hybrid AI for rare disease diagnostics using evidence-based, machine learning and language models

Dominic Boceck, Lucia Laugwitz, Marc Sturm, Daniela Bezdan, Axel Gschwind, Tobias B. Haack, Stephan Ossowski

Abstract Genome sequencing enables accurate detection of genetic variants and is transforming rare disease diagnostics. While data generation is scalable, prioritization and clinical interpretation remain challenging, often requiring expert manual classification. AI-driven decision support systems are therefore needed to assist in causal variant identification or to fully automate large-scale re-analysis of unsolved cases. Existing tools often estimate variant impact on protein function, but few integrate genomic, …

29.08.2026journal-article

International Journal of Research in Medical Sciences

Impact of obesity on clinical and angiographic characteristics in patients with ST-elevation myocardial infarction

Sinhasana Pattalegedara Tharushika Promodini, Saththiyanathan Akilan, Liudmila Kalatsei

Background: Obesity is a well-established cardiovascular risk factor and is strongly associated with metabolic dysregulation, systemic inflammation, and accelerated atherosclerosis. However, its influence on clinical presentation, laboratory parameters, and coronary angiographic characteristics in patients with ST-elevation myocardial infarction (STEMI) remains controversial. Methods: The study included 75 patients with STEMI who were admitted to the Grodno Regional Cardiological Center (Belarus) for treatment from …

29.08.2026journal-article

Asian Journal of Medicine and Health

Virtual Reality-Based Interventions for Upper Limb Rehabilitation in Parkinson’s Disease: A Scoping Review and Critical Evidence Synthesis

Krishnendu P. G., Riyas Basheer K. B., Ismail Hazim, Athul Krishna K. R., Subhashchandra Rai, Femina Hameed V. A., Nishka S. Bolar, Mohammed Sanabin

Upper-limb dysfunction in Parkinson’s disease compromises dexterity, movement scaling, coordination and the performance of everyday tasks, yet rehabilitation research has historically prioritised gait and balance. Virtual reality (VR) can deliver repetitive, task-specific practice with augmented feedback, adaptable challenge and game-based engagement, but the clinical value of VR specifically for arm and hand rehabilitation remains uncertain. This scoping review mapped and critically synthesised evidence on VR-base …

29.08.2026journal-article

Translational Medicine

Data variability in rats depending on housing and breeding conditions. Acceptability criteria for biological test systems

A. E. Katelnikova, M. A. Akimova, M. N. Makarova, V. G. Makarov, M. A. Kovaleva, E. A. Shamray, A. Yu. Pereboeva, A. S. Ivkina, D. Yu. Ivkin

Background. The reliability and reproducibility of preclinical in vivo studies significantly depend on the quality of laboratory animals. Objective. To compare the variability of clinical laboratory and behavioral parameters, as well as the level of microbiological control, in rats obtained from four breeding facilities located in the Russian Federation. Materials and Methods. This paper presents coefficient of variation (CV %) values for complete blood count parameters, biochemical analysis parameters (alanine ami …

29.08.2026journal-article

Journal of Feline Medicine and Surgery Open Reports

EXPRESS: A Case of Portal Vein Thrombosis in a Cat with Partial Splenic Rotation and Intermittent Colonic Displacement

Hyuna Kim, YONGSUK JO, Joonghyun Song

Case Summary: A 4-year-old neutered male Turkish Angora cat presented with lethargy, mental dullness and lower urinary tract signs. Hematological and biochemical analyses confirmed hepatic dysfunction. Diagnostic imaging identified portal vein thrombosis (PVT), an extrahepatic portosystemic shunt and collateral vessels surrounding the PVT. Additionally, partial splenic rotation and intermittent colonic displacement were identified. Primary hepatic disease, a common cause of PVT, could not be excluded in this patien …

29.08.2026journal-article

Journal of Wasit for Science and Medicine

<b>Assessment of SHANK3, UBE3A, Dopamine Levels, and <i>CACNA1H</i> Gene Expression in Autism Spectrum Disorder: A Case-Control Study</b>

Hayder Atta Abdul-Jabbar Hasan, Muthana Ibrahim Maleek, Noor Hameed Hussein Hamdan

This study investigated dopamine levels and changes in UBE3A, SHANK3, and CACNA1H gene expression in children with autism spectrum disorder (ASD) to enhance understanding of the biological changes associated with the disorder. The study was conducted at Al-Zahra Teaching Hospital in Al-Kut, Iraq, involving 50 children with ASD (40 males and 10 females), aged 3–12 years, and 25 healthy controls. Blood samples were collected from all participants. Dopamine, SHANK3, and UBE3A levels were measured using ELISA, while CA …

29.08.2026journal-article

Journal of Clinical Nursing

Cultural Complexities in Conducting Research With Patients With Cancer: A Qualitative Study From the Perspective of Nurse Researchers

Ruishuang Zheng, Hanfei Cui, Yanhui Wang, Qiaohong Guo, Jun Wang, Jieqiong Xia, Ping Zhu, Melissa J. Bloomer

ABSTRACT Aim To explore the cultural challenges and complexities faced by researchers conducting studies with cancer patients in the Chinese cultural context. Design A descriptive qualitative study. Methods Semi‐structured interviews were conducted with 22 nurse researchers from tertiary hospitals, medical universities, and secondary nursing colleges from all six regions in China between April 2023 and December 2024. Data were analysed using inductive thematic analysis as described by Braun and Clarke. Results From …

29.08.2026journal-article

Journal of Clinical Medicine

Dextrose Injections Across Temporomandibular Joint Mobility Disorders: A Scoping Review

Julia Kasprzycka, Maciej Chęciński, Justyna Wilk, Wojciech Macek, Maja Kosińska, Amelia Hoppe, Oliwia Jagiełło, Karolina Grzybowska-Kowalczyk, Tomasz Horodniczy, Zuzanna Baniak, Izabella Chyży, Kamila Chęcińska, Maciej Sikora

Background/Objectives: Temporomandibular joint (TMJ) mobility disorders encompass opposing clinical problems, ranging from hypermobility, subluxation, and recurrent dislocation to restricted mandibular mobility caused by disc displacement without reduction (DDwoR). Dextrose-based injections have been investigated in both settings, although their therapeutic objectives may differ. This scoping review mapped the clinical indications, injection protocols, outcomes, safety findings, and evidence gaps. Methods: PubMed/M …

29.08.2026journal-article

Translational Medicine

Dynamics of bioimpedance parameters during cardioversion in patients with atrial fibrillation

F. F. Bayramova, S. A. Zenin

Background. Heart rate conversion during cardioversion has a mixed effect on the functional response of the cardiovascular system. According to impedance cardiography data, one month after electrical cardioversion, the most significant changes were in cardiac index, cardiac power index, total peripheral resistance, and total peripheral resistance index, exceeding echocardiographic parameters in sensitivity. These data suggest that bioimpedance cardiography is a useful and timely method for dynamically monitoring he …

29.08.2026journal-article

International Journal of Research in Medical Sciences

Effectiveness of autologous leukocyte platelet-rich fibrin on orthodontic tooth movement: a split-mouth clinical study

Prahlad Jha, Vaibhav Misra, Rajeshwar Singh, Sonal Attri

Background: Prolonged orthodontic treatment is associated with increased risk of enamel demineralization, root resorption, periodontal complications and reduced patient compliance. Leukocyte platelet-rich fibrin (L-PRF), an autologous platelet concentrate rich in growth factors and cytokines, has been proposed as a biological adjunct to accelerate orthodontic tooth movement. To evaluate the effectiveness of L-PRF in enhancing orthodontic canine retraction. Methods: A split-mouth clinico-experimental study was condu …

29.08.2026journal-article

International Journal of Research in Medical Sciences

Jejunojejunal intussusception caused by a jejunal lipoma in a 92-year old patient: CT diagnosis

Samia Obilat, Yahya El Harras, Lina Lasri, Kaoutar Imrani, Ittimade Nassar

Adult intussusception is an uncommon cause of bowel obstruction and is usually associated with an identifiable pathological lead point. Among benign etiologies, submucosal lipomas of the small bowel are rare but may induce intussusception when they reach a significant size. We report the case of a 92-year-old man who presented with acute abdominal pain and subocclusive syndrome. Because of his history of bilateral inguinal hernias, strangulated hernia was initially suspected. Contrast-enhanced CT instead demonstrat …

29.08.2026journal-article

Journal of Complementary and Alternative Medical Research

Laboratory Biomarker Changes Following Extracorporeal Blood Oxygenation and Ozonation (EBOO): A Retrospective Eight-Patient Case Series

Abhinit Gupta

Background: Extracorporeal blood oxygenation and ozonation (EBOO) is an extracorporeal procedure involving oxygen-ozone exposure and blood filtration. Clinical evidence remains limited, and EBOO is investigational in many settings. Objective: To describe paired laboratory changes available before and after EBOO in eight adults treated during routine clinical care. Methods: This uncontrolled retrospective case series included eight heterogeneous patients with comparable pre- and post-procedure laboratory reports. Re …

29.08.2026journal-article

Communications Medicine

Pooled two-cohort MRI body composition phenotyping with open-source deep learning

Christian J. Mertens, Hartmut Häntze, Sebastian Ziegelmayer, Jakob Nikolas Kather, Daniel Truhn, Su Hwan Kim, Felix Busch, Dominik Weller, Benedikt Wiestler, Markus Graf, Fabian Bamberg, Christopher L. Schlett, Jakob B. Weiss, Steffen Ringhof, Elif Can, Jeanette Schulz-Menger, Thoralf Niendorf, Jacqueline Lammert, Isabel Molwitz, Avan Kader, Alessa Hering, Aymen Meddeb, Jawed Nawabi, Matthias B. Schulze, Thomas Keil, Stefan N. Willich, Lilian Krist, Martin Hadamitzky, Anke Hannemann, Florian Bassermann, Daniel Rueckert, Tobias Pischon, Alexander Hapfelmeier, Marcus R. Makowski, Keno K. Bressem, Lisa C. Adams

Abstract Background Body mass index fails to capture variation in fat and muscle distribution that determines metabolic health and disease risk. MRI enables radiation-free quantification of regional body composition, yet scalable open-source tools applied in pooled cohorts with differing acquisition protocols have been lacking. Methods MRSegmentator, an open-source nnU-Net-based pipeline, was applied to quantify visceral adipose tissue (VAT), abdominal subcutaneous adipose tissue (ASAT), gluteofemoral adipose tissu …

29.08.2026journal-article

BMC Medicine

Bladder cancer precision-cut tumor slices (PCTS) preserve functional immune microenvironment enabling ex vivo drug evaluation

Sarah Richtmann, Maja Radak, Viktor Sincic, Jenny Hugoson, Nadja Werner, Valeriia Skoryk, Darcy Wagner, Fredrik Liedberg, Kristina Lundberg

Abstract Background The development of effective cancer immunotherapies is hindered by the lack of preclinical models that faithfully preserve tumor-immune interactions. Current approaches provide limited representation of immune components, creating a critical translational gap between laboratory findings and clinical outcomes. Precision Cut Tumor Slices (PCTS) offer a promising solution by maintaining complete tumor architecture including native immune cell populations and spatial organization. Methods We establi …

29.08.2026journal-article

Diagnostics

AI-Assisted Multilabel Diagnosis of 12-Lead Electrocardiograms Using an Interpretable Stacked Deep Learning Model with External Validation

Asifa Tassaddiq, Aiman Albarakati, Rabab Alharbi, Carlo Cattani, Dalal Khalid Almutairi, Ruhaila Md Kasmani

Background: Automated interpretation of 12-lead electrocardiograms (ECGs) remains challenging because multiple abnormalities may coexist and appear in selected leads or brief waveform segments. We developed a compact and interpretable framework for five-superclass multi-label ECG diagnosis. Methods: We evaluated PTB-XL records using the official fold protocol, with folds 1–8 for training, fold 9 for validation monitoring and class-specific threshold selection, and fold 10 for independent internal testing. We then e …

29.08.2026journal-article

Foot & Ankle International

Outcomes of Iliac Crest Bone-Block Arthrodesis After Failed First MTP Joint Surgery With Bone Loss

Nurettin Mantı, Melih Atalay, Nuri Koray Ülgen, Mehmet Orçun Akkurt, Sadık Emre Erginoğlu, Ali Öznur

Background: Failed first metatarsophalangeal (MTP) joint surgery with bone loss is a challenging revision problem. This study aimed to evaluate the radiographic and clinical outcomes of iliac crest bone-block arthrodesis in this setting. Methods: This retrospective cohort included 72 patients who underwent revision first MTP arthrodesis with tricortical iliac crest autograft between 2018 and 2022. All patients had at least 2 years of clinical and radiographic follow-up, and 83.3% had at least 3 years of follow-up. …

29.08.2026journal-article

Polymers

Effects of Heat Treatment on the Mechanical Properties and Thermal Stability of Bamboo

Zilu Liang, Haiyun Jiang, Yimin Tan

Bamboo contains abundant hydrophilic components such as hemicellulose which result in poor interfacial compatibility with epoxy resin and, consequently, limit its application in bamboo–epoxy composite packaging materials. In this study, we subjected bamboo (aged 3–4 years) to vacuum heat treatment to investigate the effects of treatment temperature (140, 160, and 180 °C) and holding time (4 and 6 h) and systematically evaluated the resulting changes in density, surface color, microstructure, mechanical behavior, an …

29.08.2026journal-article

Review of Primary Care Practice and Education (Kajian Praktik dan Pendidikan Layanan Primer)

From Screen to Care: Physician Approaches to Overcoming Communication Challenges in Telemedicine

Imelda Ritunga, Mora Claramita, Sandra Widaty, Hardyanto Soebono

Background: The growth of telemedicine has encouraged physicians to adapt their communication techniques for remote consultations. Even though telemedicine enhances access and continuity of care, it also presents barriers to effective doctor–patient interaction. Aims: This study explores the communication challenges faced by physicians in telemedicine consultations and identifies the strategies they use to ensure effective and high-quality virtual care. Methods: A qualitative descriptive study was conducted through …